Fitness data for Rv1743 in Mycobacterium tuberculosis H37Rv

Probable transmembrane serine/threonine-protein kinase E PknE (protein kinase E) (STPK E)
SEED: Serine/threonine-protein kinase PknE (EC 2.7.11.1)
KEGG: serine/threonine protein kinase, bacterial

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.2)


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group condition fitness t score  
stress 7H9 with Dibucaine 0.21 mM -0.3 -1.9 compare
nitrogen source L-Valine 10 mM (N) -0.3 -1.8 compare
stress 7H9 with Nickel (II) chloride 0.6 mM -0.2 -1.7 compare
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.2 -1.5 compare
stress 7H9 with Isoniazid 0.025 ug/mL -0.2 -1.6 compare
carbon source cholesterol 100uM (C) +0.2 +1.0 compare
no stress control no stress control +0.2 +1.1 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM +0.2 +1.0 compare
stress 7H9 with Lomefloxacin 0.0035 mM +0.2 +1.4 compare
carbon source Palmitic 100 uM (C) +0.2 +1.2 compare
nitrogen source Glycine 10 mM (N) +0.2 +1.3 compare
stress 7H9 with 2,4-Dinitrophenol 0.1503 mM +0.2 +1.4 compare
stress 7H9 with Irgasan 0.065 mM +0.2 +1.5 compare
carbon source D-Glucose (C) +0.3 +2.0 compare
stress 7H9 with Linezolid 0.3 ug/mL +0.3 +1.6 compare
stress 7H9 with Cumene hydroperoxide 0.05 mM +0.3 +1.2 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 +0.4 +2.4 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 +0.4 +1.5 compare
pH pH 4.5 +0.5 +3.4 compare
pH pH 4.5 +0.6 +3.9 compare