Fitness data for Rv1731 in Mycobacterium tuberculosis H37Rv
Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2
SEED: Aldehyde dehydrogenase (EC 1.2.1.3)
KEGG: succinate-semialdehyde dehydrogenase (NADP+)
Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.2)
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| group | condition | fitness | t score | |
|---|---|---|---|---|
| no stress control | no stress control | -0.4 | -2.0 | compare |
| nitrogen source | L-Glutamic 10 mM (N) | -0.3 | -1.9 | compare |
| nitrogen source | L-Asparagine 10 mM (N) | -0.3 | -1.7 | compare |
| stress | 7H9 with Streptomycin 0.178 ug/mL | -0.3 | -1.4 | compare |
| nitrogen source | L-Serine 10 mM (N) | -0.3 | -1.8 | compare |
| stress | 7H9 with Moxifloxacin 0.121 ug/mL | -0.3 | -1.2 | compare |
| nitrogen source | L-Glutamine 10 mM (N) | -0.3 | -1.8 | compare |
| nitrogen source | L-Alanine 10 mM (N) | -0.3 | -1.8 | compare |
| carbon source | heptadecanoic 250 uM (C) | -0.2 | -1.1 | compare |
| stress | 7H9 with Pretomanid 0.213 ug/mL | -0.2 | -1.5 | compare |
| no stress control | no stress control | -0.2 | -1.3 | compare |
| carbon source | L-Asparagine (C) | -0.2 | -1.3 | compare |
| nitrogen source | Glycine 10 mM (N) | -0.2 | -1.1 | compare |
| no stress control | no stress control | -0.2 | -1.1 | compare |
| stress | 7H9 with Clarithromycin 0.967 ug/mL | +0.2 | +1.0 | compare |
| carbon source | D-Lactate 10 mM (C) | +0.2 | +1.1 | compare |
| stress | 7H9 with Clarithromycin 0.967 ug/mL | +0.2 | +1.3 | compare |
| stress | 7H9 with Dimethyl Sulfoxide 1 vol% | +0.3 | +1.4 | compare |
| carbon source | Stearic 100 uM (C) | +0.3 | +1.6 | compare |
| carbon source | Valeric 10 mM (C) | +0.3 | +1.7 | compare |