Fitness data for Rv1446c in Mycobacterium tuberculosis H37Rv

Putative OXPP cycle protein OpcA
SEED: OpcA, an allosteric effector of glucose-6-phosphate dehydrogenase, actinobacterial

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.6)


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group condition fitness t score  
stress 7H9 with 2,4-Dinitrophenol 0.1503 mM -1.2 -4.0 compare
stress 7H9 with Sisomicin 0.07 mM -1.1 -2.2 compare
stress 7H9 with Levofloxacin 0.3 ug/mL -1.1 -2.4 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -0.9 -2.1 compare
carbon source D-Lactate 10 mM (C) -0.8 -2.1 compare
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -0.8 -1.6 compare
stress 7H9 with Sisomicin 0.07 mM -0.7 -1.8 compare
no stress control no stress control -0.7 -2.0 compare
stress 7H9 with 2,4-Dinitrophenol 0.1503 mM -0.7 -2.4 compare
stress 7H9 with Erythromycin 0.016 mM -0.7 -1.9 compare
pH pH 4.5 -0.7 -1.3 compare
nitrogen source Ammonium chloride 10mM (N) -0.6 -1.4 compare
nitrogen source L-Glutamic 10 mM (N) -0.6 -2.0 compare
stress 7H9 with Chloramphenicol 0.01 mM -0.6 -1.5 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.6 -1.5 compare
stress 7H9 with Hydrogen peroxide 3.97 mM -0.6 -1.9 compare
carbon source D,L-Malic Acid 10 mM (C) -0.6 -1.6 compare
nitrogen source L-Alanine 10 mM (N) -0.6 -1.7 compare
stress 7H9 with copper (II) chloride 0.08 mM -0.6 -1.7 compare
stress 7H9 with Zinc Pyrithione 0.00072 mM +0.6 +1.5 compare