Fitness data for Rv1317c in Mycobacterium tuberculosis H37Rv

Probable bifunctional regulatory protein and DNA repair enzyme AlkA (regulatory protein of adaptative response) (methylphosphotriester-DNA--protein-cysteine S-methyltransferase)
SEED: Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63)
KEGG: AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.3)


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group condition fitness t score  
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.6 -2.7 compare
stress 7H9 with Econazole nitrate salt 0.0082 mM -0.5 -2.2 compare
stress 7H9 with Spectinomycin 0.029 mM -0.4 -1.6 compare
carbon source casaminos 1 mg/mL (C) -0.4 -1.9 compare
carbon source L-Lactate 10 mM (C) -0.4 -2.9 compare
stress 7H9 with Rifampicin 0.00045 ug/mL -0.4 -1.6 compare
no stress control no stress control -0.4 -2.5 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM -0.4 -1.4 compare
carbon source D-Lactate 10 mM (C) -0.4 -2.2 compare
stress 7H9 with Chlorpromazine 0.054 mM -0.4 -1.6 compare
stress 7H9 with Dimethyl Sulfoxide 1 vol% -0.3 -1.9 compare
pH pH 5.5 -0.3 -1.9 compare
stress 7H9 with para-aminosalicylic 0.086 ug/mL +0.4 +2.2 compare
stress 7H9 with Norfloxacin 0.125 mM +0.4 +1.7 compare
stress 7H9 with Sutezolid 0.12 ug/mL +0.4 +1.9 compare
stress 7H9 with Cumene hydroperoxide 0.05 mM +0.4 +1.1 compare
carbon source oleate 200uM (C) +0.4 +2.1 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 +0.4 +1.6 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.4 +1.5 compare
stress 7H9 with Levofloxacin 0.3 ug/mL +0.5 +1.4 compare