Fitness data for Rv1187 in Mycobacterium tuberculosis H37Rv

Probable pyrroline-5-carboxylate dehydrogenase RocA
SEED: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)
KEGG: 1-pyrroline-5-carboxylate dehydrogenase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.5)


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group condition fitness t score  
stress 7H9 with Norfloxacin 0.125 mM -0.7 -1.8 compare
stress 7H9 with Sisomicin 0.07 mM -0.7 -1.2 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -0.6 -1.5 compare
nitrogen source L-Asparagine 10 mM (N) -0.6 -1.9 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.6 -1.6 compare
carbon source D-Trehalose 10 mM (C) -0.6 -1.6 compare
nitrogen source L-Valine 10 mM (N) -0.5 -1.7 compare
carbon source D,L-Malic Acid 10 mM (C) -0.5 -1.4 compare
carbon source cholesterol 100uM (C) +0.5 +1.5 compare
stress 7H9 with Sutezolid 0.12 ug/mL +0.5 +1.6 compare
stress 7H9 with Linezolid 0.44 ug/mL +0.5 +1.5 compare
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 +0.5 +1.5 compare
no stress control no stress control +0.5 +1.6 compare
pH 7H9 pH 5.5 +0.5 +1.6 compare
nitrogen source Urea 10mM (N) +0.5 +1.6 compare
stress 7H9 with Cumene hydroperoxide 0.05 mM +0.6 +1.7 compare
stress 7H9 with Irgasan 0.065 mM +0.6 +1.7 compare
stress 7H9 with Levofloxacin 0.3 ug/mL +0.7 +2.3 compare
stress 7H9 with Amikacin di2 ug/mL +0.8 +2.8 compare
no stress control no stress control +0.8 +2.9 compare