Fitness data for Rv1187 in Mycobacterium tuberculosis H37Rv
Probable pyrroline-5-carboxylate dehydrogenase RocA
SEED: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)
KEGG: 1-pyrroline-5-carboxylate dehydrogenase
Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.3)
Or see all 101 experiments or choose conditions
| group | condition | fitness | t score | |
|---|---|---|---|---|
| nitrogen source | L-Asparagine 10 mM (N) | -0.6 | -1.9 | compare |
| carbon source | D-Trehalose 10 mM (C) | -0.6 | -1.6 | compare |
| nitrogen source | L-Valine 10 mM (N) | -0.5 | -1.7 | compare |
| carbon source | D,L-Malic Acid 10 mM (C) | -0.5 | -1.4 | compare |
| nitrogen source | L-Alanine 10 mM (N) | -0.5 | -1.6 | compare |
| carbon source | Valeric 10 mM (C) | -0.4 | -1.3 | compare |
| carbon source | L-Asparagine (C) | -0.3 | -1.3 | compare |
| carbon source | Palmitic 100 uM (C) | -0.3 | -1.1 | compare |
| carbon source | butyrate 10 mM (C) | -0.3 | -1.1 | compare |
| carbon source | Stearic 100 uM (C) | -0.3 | -1.0 | compare |
| stress | 7H9 with Moxifloxacin 0.121 ug/mL | +0.3 | +0.7 | compare |
| stress | 7H9 with Rifampicin 0.014 ug/mL | +0.3 | +0.9 | compare |
| carbon source | D-Lactate 10 mM (C) | +0.3 | +1.1 | compare |
| stress | 7H9 with Ofloxacin 0.8 ug/mL | +0.3 | +0.9 | compare |
| stress | 7H9 with Ethionamide 0.1 ug/mL | +0.3 | +0.8 | compare |
| stress | 7H9 with Clofazimine 0.45 ug/mL | +0.3 | +1.2 | compare |
| carbon source | propionate (C) | +0.4 | +1.5 | compare |
| stress | 7H9 with Moxifloxacin 0.121 ug/mL | +0.4 | +1.0 | compare |
| stress | 7H9 with Clofazimine 0.072 ug/mL | +0.4 | +1.5 | compare |
| no stress control | no stress control | +0.4 | +1.5 | compare |