Fitness data for Rv1173 in Mycobacterium tuberculosis H37Rv

Probable F420 biosynthesis protein FbiC
SEED: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 1 / 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 2
KEGG: FO synthase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 1.1)


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group condition fitness t score  
stress 7H9 with Plumbagin 0.01 mM -3.5 -3.4 compare
stress 7H9 with Menadione 0.005 mM -2.4 -3.8 compare
stress 7H9 with methylglyoxal 1.2 mM -2.0 -3.1 compare
stress 7H9 with Chlorhexidine diacetate salt 0.0021 mM -2.0 -2.5 compare
stress 7H9 with Hydrogen peroxide 3.97 mM -1.9 -3.6 compare
stress 7H9 with 8-hydroxy-nitroquinoline 0.03 mM -1.9 -2.8 compare
no stress control no stress control -1.7 -2.8 compare
stress 7H9 with Menadione 0.005 mM -1.6 -3.3 compare
stress 7H9 with copper (II) chloride 0.08 mM -1.6 -2.3 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -1.6 -2.3 compare
stress 7H9 with Hydrogen peroxide 3.97 mM -1.5 -2.1 compare
stress 7H9 with Zinc Pyrithione 0.00072 mM -1.5 -3.0 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -1.5 -2.2 compare
stress 7H9 with Formaldehyde 0.23 mM -1.2 -2.1 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM -1.1 -2.4 compare
stress 7H9 with Clofazimine 0.072 ug/mL +1.3 +3.9 compare
stress 7H9 with Delamanid 0.236 ug/mL +1.4 +5.4 compare
stress 7H9 with Delamanid 0.236 ug/mL +1.6 +6.4 compare
stress 7H9 with Pretomanid 0.213 ug/mL +2.9 +8.2 compare
stress 7H9 with Pretomanid 0.213 ug/mL +3.5 +9.3 compare