Fitness data for Rv1145 in Mycobacterium tuberculosis H37Rv

Probable conserved transmembrane transport protein MmpL13a
SEED: Integral membrane protein
KEGG: putative drug exporter of the RND superfamily

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.4)


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group condition fitness t score  
pH pH 4.5 -0.7 -1.9 compare
stress 7H9 with Sulfamethizole 0.026 mM -0.6 -2.7 compare
stress 7H9 with Ethionamide 0.1 ug/mL -0.5 -2.2 compare
stress 7H9 with Econazole nitrate salt 0.0082 mM -0.5 -2.1 compare
stress 7H9 with nitrite 3 mM; pH 5.5 -0.5 -1.5 compare
stress 7H9 with Isoniazid 0.025 ug/mL -0.4 -1.8 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -0.4 -1.4 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.4 -1.7 compare
stress 7H9 with Isoniazid 0.025 ug/mL -0.4 -1.5 compare
stress 7H9 with Ethionamide 0.1 ug/mL -0.4 -1.3 compare
stress 7H9 with copper (II) chloride 0.08 mM -0.4 -1.1 compare
stress 7H9 with Tetracycline 0.0058 mM +0.4 +1.9 compare
carbon source oleate 200uM (C) +0.4 +1.3 compare
stress 7H9 with nitrate 4 mM +0.4 +1.5 compare
stress 7H9 with Dibucaine 0.21 mM +0.4 +1.8 compare
stress 7H9 with Sutezolid 0.12 ug/mL +0.5 +2.1 compare
no stress control no stress control +0.5 +2.2 compare
stress 7H9 with Doxycycline hyclate 0.0035 mM +0.5 +2.1 compare
no stress control no stress control +0.5 +2.0 compare
stress 7H9 with Phenazine methosulfate 0.0054 mM +0.6 +2.6 compare