Fitness data for Rv1144 in Mycobacterium tuberculosis H37Rv

Probable short-chain type dehydrogenase/reductase
SEED: 3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation] (EC 1.1.1.35)

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.4)


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group condition fitness t score  
stress 7H9 with Isoniazid 0.025 ug/mL -0.6 -1.4 compare
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -0.5 -1.2 compare
stress 7H9 with Amikacin di2 ug/mL -0.5 -1.6 compare
stress 7H9 with Tetracycline 0.0058 mM -0.4 -1.4 compare
carbon source D-Lactate 10 mM (C) +0.5 +2.0 compare
stress 7H9 with Erythromycin 0.016 mM +0.5 +1.5 compare
stress 7H9 with methylglyoxal 1.2 mM +0.5 +1.7 compare
stress 7H9 with Amikacin di2 ug/mL +0.5 +1.8 compare
carbon source casaminos 1 mg/mL (C) +0.5 +2.1 compare
stress 7H9 with Benzethonium chloride 0.068 mM +0.5 +1.8 compare
stress 7H9 with Meropenem 9.6 ug/mL +0.5 +1.7 compare
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM +0.5 +2.3 compare
no stress control no stress control +0.5 +1.9 compare
no stress control no stress control +0.6 +2.0 compare
stress 7H9 with Chlorpromazine 0.054 mM +0.6 +2.2 compare
no stress control no stress control +0.6 +1.9 compare
carbon source cholesterol 100uM (C) +0.6 +2.5 compare
stress 7H9 with methylglyoxal 1.2 mM +0.6 +2.9 compare
carbon source oleate 200uM (C) +0.7 +1.7 compare
stress 7H9 with Geneticin G418 0.35 mM +0.7 +1.8 compare