Fitness data for Rv1074c in Mycobacterium tuberculosis H37Rv

Probable beta-ketoacyl CoA thiolase FadA3
SEED: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9)
KEGG: acetyl-CoA C-acetyltransferase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.3)


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group condition fitness t score  
stress 7H9 with nitrite 1.5 mM; pH 5.5 -1.2 -6.4 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.7 -3.9 compare
pH pH 4.5 -0.3 -1.9 compare
stress 7H9 with Spectinomycin 0.029 mM +0.4 +2.2 compare
no stress control no stress control +0.4 +2.6 compare
stress 7H9 with para-aminosalicylic 0.086 ug/mL +0.4 +2.7 compare
stress 7H9 with Formaldehyde 0.23 mM +0.4 +2.5 compare
stress 7H9 with Isoniazid 0.025 ug/mL +0.4 +2.3 compare
no stress control no stress control +0.4 +2.6 compare
no stress control no stress control +0.4 +2.5 compare
no stress control no stress control +0.4 +2.5 compare
stress 7H9 with Ethionamide 0.1 ug/mL +0.4 +2.7 compare
stress 7H9 with Ethionamide 0.1 ug/mL +0.4 +2.9 compare
no stress control no stress control +0.5 +3.3 compare
stress 7H9 with Levofloxacin 0.3 ug/mL +0.5 +2.5 compare
stress 7H9 with Streptomycin 0.178 ug/mL +0.5 +3.5 compare
stress 7H9 with Dodecyl Sulfate 0.02 vol% +0.5 +3.1 compare
stress 7H9 with Isoniazid 0.025 ug/mL +0.5 +3.1 compare
stress 7H9 with Streptomycin 0.178 ug/mL +0.6 +4.2 compare
stress 7H9 with Dodecyl Sulfate 0.02 vol% +0.6 +4.3 compare