Fitness data for Rv1058 in Mycobacterium tuberculosis H37Rv
Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)
SEED: Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD14
KEGG: fatty-acyl-CoA synthase
Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.6)
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| group | condition | fitness | t score | |
|---|---|---|---|---|
| carbon source | propionate (C) | -1.4 | -6.0 | compare |
| carbon source | propionate (C) | -1.4 | -5.9 | compare |
| carbon source | butyrate 10 mM (C) | -1.2 | -4.8 | compare |
| stress | 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 | -0.9 | -2.2 | compare |
| nitrogen source | L-Glutamine 10 mM (N) | -0.8 | -2.9 | compare |
| carbon source | oleate 200uM (C) | -0.8 | -3.2 | compare |
| nitrogen source | L-Asparagine 10 mM (N) | -0.8 | -2.3 | compare |
| stress | 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM | -0.7 | -1.5 | compare |
| nitrogen source | Glycine 10 mM (N) | -0.7 | -3.2 | compare |
| carbon source | oleate 200uM (C) | -0.7 | -2.6 | compare |
| no stress control | no stress control | -0.6 | -2.0 | compare |
| carbon source | Stearic 100 uM (C) | -0.6 | -2.2 | compare |
| carbon source | butyrate 10 mM (C) | -0.6 | -2.9 | compare |
| carbon source | Valeric 10 mM (C) | -0.6 | -2.2 | compare |
| stress | 7H9 with Chlorpromazine 0.054 mM | -0.6 | -2.2 | compare |
| no stress control | no stress control | -0.6 | -1.6 | compare |
| nitrogen source | L-Asparagine 10 mM (N) | -0.6 | -2.1 | compare |
| stress | 7H9 with Doxycycline hyclate 0.0035 mM | -0.6 | -2.3 | compare |
| stress | 7H9 with Ramoplanin 0.009 mM | +0.6 | +1.8 | compare |
| pH | pH 4.5 | +0.7 | +1.8 | compare |