Fitness data for Rv0971c in Mycobacterium tuberculosis H37Rv

Probable enoyl-CoA hydratase EchA7 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase)
SEED: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
KEGG: enoyl-CoA hydratase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.7)


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group condition fitness t score  
stress 7H9 with Cloxacillin 0.0386 mM -1.2 -3.2 compare
stress 7H9 with Delamanid 0.236 ug/mL -1.1 -2.9 compare
stress 7H9 with Clarithromycin 0.967 ug/mL -1.0 -2.3 compare
stress 7H9 with Delamanid 0.236 ug/mL -1.0 -3.2 compare
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM -0.9 -3.0 compare
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM -0.9 -1.7 compare
carbon source L-Lactate 10 mM (C) -0.8 -2.6 compare
carbon source D-Trehalose 10 mM (C) -0.8 -2.0 compare
carbon source L-Lactate 10 mM (C) -0.8 -1.8 compare
stress 7H9 with Clofazimine 0.45 ug/mL -0.8 -2.3 compare
carbon source casaminos 1 mg/mL (C) -0.8 -2.2 compare
stress 7H9 with Clarithromycin 0.967 ug/mL -0.8 -3.0 compare
stress 7H9 with Cumene hydroperoxide 0.05 mM -0.7 -3.4 compare
stress 7H9 with Cloxacillin 0.0386 mM -0.7 -1.5 compare
no stress control no stress control -0.7 -3.3 compare
stress 7H9 with Isoniazid 0.025 ug/mL +0.7 +1.4 compare
stress 7H9 with Isoniazid 0.025 ug/mL +0.7 +1.2 compare
pH pH 5.5 +0.8 +2.2 compare
pH pH 5.5 +0.8 +2.1 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 +1.1 +2.4 compare