Fitness data for Rv0949 in Mycobacterium tuberculosis H37Rv

Probable ATP-dependent DNA helicase II UvrD1
SEED: ATP-dependent DNA helicase UvrD/PcrA
KEGG: DNA helicase II / ATP-dependent DNA helicase PcrA

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 2.9)


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group condition fitness t score  
stress 7H9 with Doxycycline hyclate 0.0035 mM -4.4 -1.4 compare
stress 7H9 with Doxycycline hyclate 0.0035 mM -4.4 -1.3 compare
stress 7H9 with Cumene hydroperoxide 0.05 mM -4.4 -1.3 compare
stress 7H9 with Hygromycin B 0.0095 mM -4.3 -1.3 compare
stress 7H9 with nitrite 3 mM; pH 5.5 -4.1 -1.1 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL -4.0 -1.3 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -4.0 -1.1 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -3.9 -0.9 compare
stress 7H9 with Ethionamide 0.1 ug/mL -3.8 -1.4 compare
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM -3.8 -1.2 compare
stress 7H9 with Dodecyl Sulfate 0.02 vol% -3.8 -1.1 compare
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM -3.7 -1.1 compare
stress 7H9 with Levofloxacin 0.3 ug/mL -3.7 -1.4 compare
stress 7H9 with Ethionamide 0.1 ug/mL -3.7 -1.4 compare
stress 7H9 with Phenazine ethosulfate 0.0137 mM -3.7 -1.3 compare
stress 7H9 with hypochlorite 0.4 vol% -3.6 -1.0 compare
stress 7H9 with EDTA (disodium salt) 0.2 mM -3.5 -1.1 compare
stress 7H9 with methylglyoxal 1.2 mM -3.4 -1.0 compare
nitrogen source L-Serine 10 mM (N) -3.0 -1.4 compare
nitrogen source Glycine 10 mM (N) -2.9 -1.4 compare