Fitness data for Rv0939 in Mycobacterium tuberculosis H37Rv

Possible bifunctional enzyme: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase) + cyclase/dehydrase
SEED: Fumarylacetoacetase (EC 3.7.1.2)

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 1.5)


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group condition fitness t score  
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM -3.3 -1.4 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -3.2 -1.4 compare
no stress control no stress control -2.5 -1.4 compare
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM -2.4 -1.4 compare
stress 7H9 with Antimycin A 0.0186 mM -2.2 -1.2 compare
stress 7H9 with nitrite 5 mM -1.9 -1.3 compare
nitrogen source Ammonium chloride 10mM (N) -1.8 -0.8 compare
stress 7H9 with Phenazine ethosulfate 0.0137 mM -1.8 -1.1 compare
no stress control no stress control -1.7 -0.7 compare
stress 7H9 with 8-hydroxy-nitroquinoline 0.03 mM -1.6 -0.6 compare
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -1.6 -1.1 compare
no stress control no stress control -1.6 -0.9 compare
pH pH 5.5 -1.5 -1.2 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL +1.5 +1.8 compare
stress 7H9 with Linezolid 0.3 ug/mL +1.5 +0.9 compare
nitrogen source L-Valine 10 mM (N) +1.5 +1.8 compare
stress 7H9 with Tetrazolium violet 0.065 mM +1.6 +1.3 compare
stress 7H9 with Menadione 0.005 mM +1.6 +1.8 compare
stress 7H9 with 8-hydroxy-nitroquinoline 0.03 mM +1.6 +1.6 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL +1.7 +1.6 compare