Fitness data for Rv0938 in Mycobacterium tuberculosis H37Rv

ATP dependent DNA ligase LigD (ATP dependent polydeoxyribonucleotide synthase) (thermostable DNA ligase) (ATP dependent polynucleotide ligase) (sealase) (DNA repair enzyme) (DNA joinase)
SEED: ATP-dependent DNA ligase (EC 6.5.1.1) clustered with Ku protein, LigD
KEGG: DNA ligase (ATP)

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.5)


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group condition fitness t score  
stress 7H9 with copper (II) chloride 0.08 mM -0.7 -1.3 compare
no stress control no stress control -0.6 -1.9 compare
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.6 -1.6 compare
stress 7H9 with Streptomycin 0.178 ug/mL -0.5 -1.4 compare
stress 7H9 with Chloramphenicol 0.01 mM -0.5 -2.0 compare
carbon source D,L-Malic Acid 10 mM (C) -0.5 -1.3 compare
pH pH 5.5 -0.5 -1.8 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 +0.5 +2.2 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 +0.5 +1.4 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 +0.5 +1.8 compare
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +0.5 +0.9 compare
stress 7H9 with Tetrazolium violet 0.065 mM +0.5 +0.9 compare
stress 7H9 with Ofloxacin 0.8 ug/mL +0.5 +1.7 compare
stress 7H9 with Isoniazid 0.025 ug/mL +0.5 +1.8 compare
stress 7H9 with Irgasan 0.065 mM +0.5 +1.2 compare
stress 7H9 with nitrate 4 mM +0.7 +1.7 compare
stress 7H9 with Phenazine methosulfate 0.0054 mM +0.7 +1.3 compare
no stress control no stress control +0.9 +3.6 compare
stress 7H9 with Geneticin G418 0.35 mM +1.0 +2.8 compare
stress 7H9 with Nickel (II) chloride 0.6 mM +1.0 +1.7 compare