Fitness data for Rv0805 in Mycobacterium tuberculosis H37Rv

Class III cyclic nucleotide phosphodiesterase (cNMP PDE)
SEED: 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17)

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 1.7)


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group condition fitness t score  
stress 7H9 with Sisomicin 0.07 mM -2.7 -1.1 compare
carbon source casaminos 1 mg/mL (C) -2.4 -1.5 compare
carbon source Valeric 10 mM (C) -2.1 -1.5 compare
stress 7H9 with Doxycycline hyclate 0.0035 mM -2.1 -0.8 compare
stress 7H9 with Ethionamide 0.1 ug/mL -2.0 -1.0 compare
stress 7H9 with Hygromycin B 0.0095 mM -1.9 -1.5 compare
no stress control no stress control -1.8 -1.3 compare
carbon source propionate (C) -1.8 -1.1 compare
stress 7H9 with Pretomanid 0.213 ug/mL -1.8 -1.5 compare
stress 7H9 with Clarithromycin 0.967 ug/mL -1.7 -1.5 compare
stress 7H9 with Lomefloxacin 0.0035 mM +1.7 +1.5 compare
stress 7H9 with Lomefloxacin 0.0035 mM +1.7 +2.1 compare
stress 7H9 with Cloxacillin 0.0386 mM +1.7 +1.9 compare
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM +2.0 +2.4 compare
stress 7H9 with Antimycin A 0.0186 mM +2.0 +1.8 compare
no stress control no stress control +2.0 +1.8 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 +2.2 +2.5 compare
stress 7H9 with Linezolid 0.44 ug/mL +2.2 +3.6 compare
pH pH 5.5 +2.3 +3.3 compare
stress 7H9 with Cloxacillin 0.0386 mM +2.5 +2.8 compare