Fitness data for Rv0764c in Mycobacterium tuberculosis H37Rv

Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM)
SEED: Lanosterol 14-alpha demethylase @ Cytochrome P450 51 (EC 1.14.13.70)
KEGG: cytochrome P450, family 51 (sterol 14-demethylase)

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.5)


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group condition fitness t score  
no stress control no stress control -0.8 -2.0 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.7 -1.7 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -0.7 -1.3 compare
pH pH 5.5 -0.6 -1.7 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -0.5 -2.0 compare
no stress control no stress control +0.5 +2.3 compare
stress 7H9 with Cumene hydroperoxide 0.05 mM +0.5 +1.2 compare
nitrogen source L-Glutamine 10 mM (N) +0.5 +2.2 compare
stress 7H9 with Dodecyl Sulfate 0.02 vol% +0.6 +1.7 compare
carbon source oleate 200uM (C) +0.6 +0.6 compare
nitrogen source Ammonium chloride 10mM (N) +0.6 +1.6 compare
nitrogen source L-Asparagine 10 mM (N) +0.6 +2.6 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM +0.6 +1.5 compare
nitrogen source Ammonium chloride 10mM (N) +0.6 +2.5 compare
stress 7H9 with Clofazimine 0.072 ug/mL +0.6 +2.9 compare
nitrogen source L-Alanine 10 mM (N) +0.7 +1.9 compare
stress 7H9 with Dimethyl Sulfoxide 1 vol% +0.7 +1.7 compare
pH 7H9 pH 5.5 +0.7 +2.0 compare
stress 7H9 with Streptomycin 0.178 ug/mL +0.7 +2.1 compare
stress 7H9 with Linezolid 0.44 ug/mL +0.8 +1.4 compare