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  • Fitness data for Rv0598c in Mycobacterium tuberculosis H37Rv

    Possible toxin VapC27. Contains PIN domain.
    SEED: Toxin 1, PIN domain

    Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.6)


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    group condition fitness t score  
    stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -0.9 -1.0 compare
    stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.7 -1.6 compare
    pH pH 4.5 -0.7 -1.1 compare
    stress 7H9 with Delamanid 0.236 ug/mL -0.7 -1.5 compare
    stress 7H9 with Spectinomycin 0.029 mM -0.6 -0.9 compare
    stress 7H9 with Irgasan 0.065 mM -0.6 -1.2 compare
    stress 7H9 with Chlorhexidine diacetate salt 0.0021 mM -0.6 -1.7 compare
    stress 7H9 with Bedaquiline 0.15 ug/mL +0.6 +2.5 compare
    no stress control no stress control +0.6 +1.2 compare
    carbon source D-Trehalose 10 mM (C) +0.6 +1.9 compare
    stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM +0.6 +0.8 compare
    stress 7H9 with Linezolid 0.44 ug/mL +0.6 +1.9 compare
    stress 7H9 with copper (II) chloride 0.08 mM +0.7 +1.3 compare
    stress 7H9 with methylglyoxal 1.2 mM +0.7 +1.6 compare
    carbon source D-Lactate 10 mM (C) +0.7 +2.4 compare
    carbon source propionate (C) +0.7 +1.7 compare
    carbon source cholesterol 100uM (C) +0.7 +1.9 compare
    nitrogen source L-Glutamine 10 mM (N) +0.8 +2.0 compare
    stress 7H9 with Clofazimine 0.45 ug/mL +0.8 +2.7 compare
    stress 7H9 with Norfloxacin 0.125 mM +0.9 +1.3 compare