Fitness data for Rv0570 in Mycobacterium tuberculosis H37Rv

Probable ribonucleoside-diphosphate reductase (large subunit) NrdZ (ribonucleotide reductase)
SEED: Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1)
KEGG: ribonucleoside-diphosphate reductase alpha chain

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.3)


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group condition fitness t score  
stress 7H9 with nitrite 2.5 mM -0.5 -2.2 compare
stress 7H9 with Ofloxacin 0.8 ug/mL -0.5 -2.1 compare
stress 7H9 with Cumene hydroperoxide 0.05 mM -0.4 -2.1 compare
stress 7H9 with Ofloxacin 0.8 ug/mL -0.4 -1.6 compare
no stress control no stress control -0.4 -2.0 compare
nitrogen source L-Glutamic 10 mM (N) -0.4 -1.2 compare
stress 7H9 with Tetrazolium violet 0.065 mM -0.4 -1.5 compare
nitrogen source L-Glutamine 10 mM (N) -0.4 -1.7 compare
no stress control no stress control -0.3 -1.3 compare
nitrogen source L-Alanine 10 mM (N) -0.3 -1.5 compare
stress 7H9 with Pretomanid 0.213 ug/mL +0.3 +1.3 compare
stress 7H9 with Clofazimine 0.45 ug/mL +0.4 +1.6 compare
stress 7H9 with hypochlorite 0.4 vol% +0.4 +1.6 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 +0.4 +1.7 compare
stress 7H9 with Doxycycline hyclate 0.0035 mM +0.4 +2.3 compare
no stress control no stress control +0.4 +1.8 compare
stress 7H9 with Tetracycline 0.0058 mM +0.4 +2.0 compare
stress 7H9 with Dodecyl Sulfate 0.02 vol% +0.5 +1.5 compare
stress 7H9 with Chlorpromazine 0.054 mM +0.5 +2.0 compare
pH pH 4.5 +0.6 +1.9 compare