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  • Fitness data for Rv0470c in Mycobacterium tuberculosis H37Rv

    Mycolic acid synthase PcaA (cyclopropane synthase)
    KEGG: cyclopropane-fatty-acyl-phospholipid synthase

    Top 20 experiments with the strongest phenotypes (|fitness| ≥ 1.0)


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    group condition fitness t score  
    stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -2.0 -2.9 compare
    stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -1.6 -2.8 compare
    stress 7H9 with Irgasan 0.065 mM -1.5 -4.0 compare
    stress 7H9 with nitrite 3 mM; pH 5.5 -1.5 -2.4 compare
    carbon source cholesterol 100uM (C) -1.5 -3.3 compare
    stress 7H9 with Cumene hydroperoxide 0.05 mM -1.4 -2.8 compare
    stress 7H9 with Isoniazid 0.025 ug/mL -1.4 -2.4 compare
    stress 7H9 with Irgasan 0.065 mM -1.3 -2.9 compare
    pH pH 4.5 -1.3 -2.8 compare
    stress 7H9 with Nickel (II) chloride 0.6 mM -1.2 -1.8 compare
    stress 7H9 with 2,4-Dinitrophenol 0.1503 mM -1.2 -2.8 compare
    stress 7H9 with Ethionamide 0.1 ug/mL -1.1 -2.1 compare
    stress 7H9 with nitrate 4 mM -1.1 -1.5 compare
    stress 7H9 with nitrite 1.5 mM; pH 5.5 -1.1 -3.0 compare
    nitrogen source L-Asparagine 10 mM (N) -1.1 -2.2 compare
    stress 7H9 with Delamanid 0.236 ug/mL -1.1 -3.5 compare
    stress 7H9 with Dimethyl Sulfoxide 1 vol% -1.0 -2.4 compare
    nitrogen source Ammonium chloride 10mM (N) -1.0 -1.8 compare
    stress 7H9 with Rifampicin 0.014 ug/mL +1.8 +5.2 compare
    stress 7H9 with Rifampicin 0.014 ug/mL +1.9 +4.8 compare