Fitness data for Rv0468 in Mycobacterium tuberculosis H37Rv

3-hydroxybutyryl-CoA dehydrogenase FadB2 (beta-hydroxybutyryl-CoA dehydrogenase) (BHBD)
SEED: 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)
KEGG: 3-hydroxybutyryl-CoA dehydrogenase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.8)


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group condition fitness t score  
stress 7H9 with Cumene hydroperoxide 0.05 mM -1.2 -1.3 compare
stress 7H9 with Menadione 0.005 mM -1.1 -1.8 compare
stress 7H9 with Menadione 0.005 mM -1.1 -2.3 compare
stress 7H9 with Sisomicin 0.07 mM -1.0 -1.3 compare
stress 7H9 with Levofloxacin 0.3 ug/mL -1.0 -1.3 compare
stress 7H9 with Zinc Pyrithione 0.00072 mM -0.8 -1.5 compare
stress 7H9 with Dicloxacillin 0.0069 mM +0.8 +2.0 compare
stress 7H9 with Clofazimine 0.45 ug/mL +0.8 +1.6 compare
pH pH 4.5 +0.8 +1.1 compare
stress 7H9 with Norfloxacin 0.125 mM +0.9 +2.5 compare
no stress control no stress control +0.9 +2.0 compare
stress 7H9 with nitrite 2.5 mM +0.9 +1.8 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM +0.9 +1.9 compare
stress 7H9 with nitrite 5 mM +1.0 +3.0 compare
stress 7H9 with Ramoplanin 0.009 mM +1.0 +3.8 compare
stress 7H9 with Meropenem 9.6 ug/mL +1.0 +4.0 compare
stress 7H9 with Novobiocin 0.004 mM +1.1 +2.5 compare
stress 7H9 with Cloxacillin 0.0386 mM +1.1 +2.8 compare
stress 7H9 with Isoniazid 0.025 ug/mL +1.1 +2.2 compare
stress 7H9 with Rifampicin 0.00045 ug/mL +1.2 +2.5 compare