Fitness data for Rv0405 in Mycobacterium tuberculosis H37Rv
Probable membrane bound polyketide synthase Pks6
SEED: Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39)
Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.2)
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| group | condition | fitness | t score | |
|---|---|---|---|---|
| carbon source | heptadecanoic 250 uM (C) | -0.3 | -2.3 | compare |
| carbon source | Palmitic 100 uM (C) | -0.3 | -2.4 | compare |
| stress | 7H9 with Isoniazid 0.025 ug/mL | -0.3 | -1.7 | compare |
| no stress control | no stress control | -0.3 | -2.0 | compare |
| stress | 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 | -0.2 | -1.8 | compare |
| stress | 7H9 with Moxifloxacin 0.121 ug/mL | -0.2 | -1.3 | compare |
| stress | 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 | +0.2 | +1.2 | compare |
| nitrogen source | L-Aspartic Acid 10 mM (N) | +0.2 | +1.6 | compare |
| nitrogen source | L-Asparagine 10 mM (N) | +0.2 | +1.5 | compare |
| stress | 7H9 with Meropenem 9.6 ug/mL | +0.2 | +1.5 | compare |
| no stress control | no stress control | +0.2 | +1.7 | compare |
| nitrogen source | L-Glutamine 10 mM (N) | +0.2 | +1.5 | compare |
| nitrogen source | L-Asparagine 10 mM (N) | +0.3 | +1.6 | compare |
| nitrogen source | L-Valine 10 mM (N) | +0.3 | +1.8 | compare |
| nitrogen source | L-Valine 10 mM (N) | +0.3 | +1.9 | compare |
| nitrogen source | L-Aspartic Acid 10 mM (N) | +0.3 | +2.0 | compare |
| stress | 7H9 with Pretomanid 0.213 ug/mL | +0.3 | +1.7 | compare |
| nitrogen source | L-Alanine 10 mM (N) | +0.3 | +2.3 | compare |
| nitrogen source | Glycine 10 mM (N) | +0.3 | +2.3 | compare |
| stress | 7H9 with Geneticin G418 0.35 mM | +0.3 | +2.4 | compare |