Fitness data for Rv0319 in Mycobacterium tuberculosis H37Rv

Probable pyrrolidone-carboxylate peptidase Pcp (5-oxoprolyl-peptidase) (pyroglutamyl-peptidase I) (PGP-I) (pyrase)
SEED: Pyrrolidone-carboxylate peptidase (EC 3.4.19.3)
KEGG: pyroglutamyl-peptidase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.5)


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group condition fitness t score  
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -0.8 -1.3 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.7 -2.1 compare
stress 7H9 with Isoniazid 0.025 ug/mL -0.7 -2.4 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -0.6 -1.7 compare
nitrogen source Ammonium chloride 10mM (N) -0.6 -2.0 compare
stress 7H9 with Nickel (II) chloride 0.6 mM -0.5 -1.4 compare
stress 7H9 with Levofloxacin 0.3 ug/mL -0.5 -1.6 compare
stress 7H9 with Ofloxacin 0.8 ug/mL -0.5 -2.0 compare
stress 7H9 with Phenazine ethosulfate 0.0137 mM -0.5 -1.5 compare
nitrogen source L-Asparagine 10 mM (N) -0.5 -1.2 compare
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.5 -1.4 compare
stress 7H9 with EDTA (disodium salt) 0.2 mM -0.5 -1.5 compare
carbon source oleate 200uM (C) +0.5 +1.2 compare
stress 7H9 with nitrate 4 mM +0.5 +1.3 compare
stress 7H9 with 8-hydroxy-nitroquinoline 0.03 mM +0.5 +1.9 compare
stress 7H9 with Econazole nitrate salt 0.0082 mM +0.5 +1.7 compare
stress 7H9 with Meropenem 9.6 ug/mL +0.5 +2.5 compare
carbon source pyruvate (C) +0.6 +2.2 compare
stress 7H9 with Streptomycin 0.178 ug/mL +0.8 +1.5 compare
stress 7H9 with Sisomicin 0.07 mM +0.8 +1.8 compare