Fitness data for Rv0234c in Mycobacterium tuberculosis H37Rv

Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1
SEED: Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16)
KEGG: succinate-semialdehyde dehydrogenase (NADP+)

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.6)


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group condition fitness t score  
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -1.4 -2.9 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -1.2 -2.8 compare
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -1.1 -2.9 compare
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -1.0 -1.7 compare
pH pH 4.5 -0.8 -2.0 compare
pH 7H9 pH 5.5 -0.7 -2.0 compare
stress 7H9 with copper (II) chloride 0.08 mM -0.7 -1.3 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM -0.6 -1.5 compare
nitrogen source L-Glutamine 10 mM (N) +0.6 +1.1 compare
no stress control no stress control +0.7 +1.2 compare
stress 7H9 with Chloramphenicol 0.01 mM +0.7 +2.6 compare
stress 7H9 with Chlorpromazine 0.054 mM +0.7 +2.0 compare
stress 7H9 with Isoniazid 0.025 ug/mL +0.7 +2.1 compare
stress 7H9 with Ethionamide 0.1 ug/mL +0.7 +1.6 compare
stress 7H9 with Rifampicin 0.014 ug/mL +0.7 +2.6 compare
stress 7H9 with Geneticin G418 0.35 mM +0.7 +1.7 compare
stress 7H9 with methylglyoxal 1.2 mM +0.8 +3.1 compare
stress 7H9 with Isoniazid 0.025 ug/mL +0.8 +2.7 compare
stress 7H9 with Rifampicin 0.014 ug/mL +0.9 +2.6 compare
stress 7H9 with Dimethyl Sulfoxide 1 vol% +1.0 +2.5 compare