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  • Fitness data for Rv0216 in Mycobacterium tuberculosis H37Rv

    Double hotdog hydratase
    SEED: Mesaconyl-CoA hydratase

    Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.4)


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    group condition fitness t score  
    stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM -0.7 -1.6 compare
    stress 7H9 with Novobiocin 0.004 mM -0.6 -1.9 compare
    stress 7H9 with Levofloxacin 0.3 ug/mL -0.5 -1.1 compare
    stress 7H9 with Isoniazid 0.025 ug/mL -0.5 -0.9 compare
    stress 7H9 with Menadione 0.005 mM -0.5 -1.2 compare
    stress 7H9 with Linezolid 0.3 ug/mL -0.5 -1.2 compare
    stress 7H9 with Clofazimine 0.45 ug/mL -0.5 -1.2 compare
    stress 7H9 with Erythromycin 0.016 mM -0.4 -1.1 compare
    stress 7H9 with Novobiocin 0.004 mM -0.4 -1.4 compare
    stress 7H9 with Ethionamide 0.1 ug/mL -0.4 -0.9 compare
    nitrogen source Ammonium chloride 10mM (N) +0.4 +1.3 compare
    stress 7H9 with Clofazimine 0.45 ug/mL +0.4 +1.6 compare
    no stress control no stress control +0.5 +1.4 compare
    stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM +0.5 +1.4 compare
    nitrogen source Ammonium chloride 10mM (N) +0.5 +1.6 compare
    stress 7H9 with methylglyoxal 1.2 mM +0.6 +1.6 compare
    stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM +0.6 +1.8 compare
    stress 7H9 with Sisomicin 0.07 mM +0.6 +1.4 compare
    stress 7H9 with Meropenem 9.6 ug/mL +0.7 +2.4 compare
    stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 +1.0 +3.3 compare