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  • Fitness data for Rv0071 in Mycobacterium tuberculosis H37Rv

    Possible maturase
    SEED: Retron-type RNA-directed DNA polymerase (EC 2.7.7.49)

    Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.3)


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    group condition fitness t score  
    stress 7H9 with Levofloxacin 0.3 ug/mL -0.7 -1.9 compare
    pH pH 4.5 -0.6 -2.3 compare
    pH pH 5.5 -0.6 -1.9 compare
    no stress control no stress control -0.5 -2.1 compare
    stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.5 -1.8 compare
    stress 7H9 with Menadione 0.005 mM -0.5 -2.1 compare
    stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -0.4 -1.7 compare
    carbon source L-Asparagine (C) -0.4 -2.0 compare
    stress 7H9 with Ofloxacin 0.8 ug/mL -0.4 -1.6 compare
    stress 7H9 with Moxifloxacin 0.121 ug/mL -0.4 -2.0 compare
    carbon source Stearic 100 uM (C) -0.4 -1.1 compare
    stress 7H9 with Zinc Pyrithione 0.00072 mM -0.4 -2.0 compare
    pH pH 4.5 -0.3 -1.5 compare
    stress 7H9 with Ethionamide 0.1 ug/mL -0.3 -1.5 compare
    pH 7H9 pH 5.5 +0.3 +1.3 compare
    stress 7H9 with Cumene hydroperoxide 0.05 mM +0.3 +1.5 compare
    stress 7H9 with Doxycycline hyclate 0.0035 mM +0.3 +1.1 compare
    stress 7H9 with Cumene hydroperoxide 0.05 mM +0.4 +1.5 compare
    stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 +0.4 +1.5 compare
    stress 7H9 with Norfloxacin 0.125 mM +0.5 +1.6 compare