Fitness data for Rv0050 in Mycobacterium tuberculosis H37Rv

Probable bifunctional penicillin-binding protein 1A/1B PonA1 (murein polymerase) (PBP1): penicillin-insensitive transglycosylase (peptidoglycan TGASE) + penicillin-sensitive transpeptidase (DD-transpeptidase)
SEED: Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 1.0)


Add gene:

Or see all 236 experiments or choose conditions

group condition fitness t score  
stress 7H9 with Pretomanid 0.213 ug/mL -2.2 -4.8 compare
stress 7H9 with Vancomycin Hydrochloride from Streptomyces orientalis 0.012 mM -2.0 -4.2 compare
stress 7H9 with Phenazine methosulfate 0.0054 mM -1.7 -3.0 compare
stress 7H9 with Pretomanid 0.213 ug/mL -1.7 -4.3 compare
stress 7H9 with Ethambutol 0.75 ug/mL -1.7 -2.6 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL -1.6 -2.6 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -1.5 -2.6 compare
stress 7H9 with Ramoplanin 0.009 mM -1.5 -2.7 compare
stress 7H9 with Meropenem 9.6 ug/mL -1.4 -2.8 compare
stress 7H9 with Rifampicin 0.014 ug/mL -1.4 -2.1 compare
carbon source Valeric 10 mM (C) -1.3 -3.4 compare
stress 7H9 with Irgasan 0.065 mM -1.2 -2.0 compare
stress 7H9 with Sulfamethizole 0.026 mM -1.1 -2.6 compare
stress 7H9 with Doxycycline hyclate 0.0035 mM -1.1 -3.0 compare
pH 7H9 pH 5.5 -1.1 -1.9 compare
stress 7H9 with Benzethonium chloride 0.068 mM -1.0 -2.9 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -1.0 -2.0 compare
stress 7H9 with copper (II) chloride 0.08 mM -1.0 -1.8 compare
carbon source Stearic 100 uM (C) -1.0 -2.0 compare
pH pH 4.5 -1.0 -2.1 compare