Fitness data for Rv0016c in Mycobacterium tuberculosis H37Rv

Probable penicillin-binding protein PbpA
SEED: Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129)
KEGG: peptidoglycan glycosyltransferase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 1.3)


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group condition fitness t score  
pH pH 4.5 -2.6 -6.0 compare
pH pH 4.5 -2.3 -3.9 compare
stress 7H9 with methylglyoxal 1.2 mM -1.9 -4.8 compare
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM -1.8 -4.6 compare
stress 7H9 with Hydrogen peroxide 3.97 mM -1.8 -5.3 compare
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -1.8 -2.8 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -1.6 -5.1 compare
stress 7H9 with Ethambutol 0.75 ug/mL -1.5 -4.1 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -1.5 -5.6 compare
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM -1.5 -5.5 compare
stress 7H9 with Zinc Pyrithione 0.00072 mM -1.4 -4.2 compare
stress 7H9 with Zinc Pyrithione 0.00072 mM -1.4 -4.1 compare
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM -1.4 -3.7 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -1.4 -4.6 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -1.4 -4.6 compare
stress 7H9 with Hydrogen peroxide 3.97 mM -1.4 -4.1 compare
stress 7H9 with Ethambutol 0.75 ug/mL -1.4 -5.7 compare
carbon source Glycerol (C) -1.4 -3.5 compare
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM -1.3 -4.2 compare
no stress control no stress control -1.3 -3.9 compare