DNA topoisomerase I
SEED: DNA topoisomerase I (EC 5.99.1.2)
KEGG: DNA topoisomerase I
Top 20 experiments with the strongest phenotypes (|fitness| ≥ 2.6)
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| group | condition | fitness | t score | |
|---|
| nitrogen source | H2 N-free with 10mM L-Glutamic | -3.6 | -9.3 | compare |
| nitrogen source | H2 N-free with 10mM L-Glutamic | -3.4 | -9.0 | compare |
| stress | McCas_H2_complete Hydroxylamine 2.08333333333333 mM | -3.2 | -6.7 | compare |
| stress | McCas_H2_complete Lithium chloride 250 mM | -3.0 | -7.0 | compare |
| rich t2 | H2 McCas, 2.5g/L bicarb, 200 mM MOPs, 40 psi H2CO2, SO4 FREE | -2.8 | -5.8 | compare |
| stress | H2 McCas with 40 minute oxygen exposure | -2.7 | -8.0 | compare |
| mixed community | Mixed culture; Syntrophotalea carbinolica 1:1 starting OD to methanogen; Ethanol_timecourse1; 20 generations | -2.7 | -4.7 | compare |
| rich t2 | H2 McCas, 2.5g/L bicarb, 200 mM MOPs, 40 psi H2CO2, SO4 FREE | -2.7 | -6.3 | compare |
| nitrogen source | H2 N-free with 10mM L-Proline | -2.7 | -6.8 | compare |
| nitrogen source | H2 N-free with 10mM L-Lysine | -2.7 | -6.6 | compare |
| nitrogen source | H2 N-free with 10mM Cytidine | -2.7 | -9.6 | compare |
| stress | H2 McCas with 1 mM polysulfide | -2.7 | -6.1 | compare |
| stress | McCas_H2_complete sodium bromide 250 mM | -2.7 | -4.9 | compare |
| nitrogen source | H2 N-free with 10mM L-Citrulline | -2.7 | -8.1 | compare |
| stress | H2 McCas with 1 mM Na2S | -2.6 | -6.6 | compare |
| nitrogen source | H2 N-free with 10mM L-Lysine | -2.6 | -6.5 | compare |
| rich t2 | H2 McCas, 2.5g/L bicarb, 200 mM MOPs, 40 psi H2CO2, SO4 FREE | -2.6 | -6.2 | compare |
| nutrient t2 | H2 deepwell vitamin FREE | -2.6 | -5.0 | compare |
| nitrogen source | H2 N-free with 10mM L-Tryptophan | -2.6 | -8.4 | compare |
| nutrient t2 | H2 McCas, 2.5g/L bicarb, 200 mM MOPs, 40 psi H2CO2, SO4 & Casamino Acid FREE | -2.6 | -6.8 | compare |