2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
SEED: Small primase-like proteins (Toprim domain) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
KEGG: 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.5)
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| group | condition | fitness | t score | |
|---|
| stress | McCas_formate_complete sodium nitrite 0.416666666666667 mM | -1.1 | -2.9 | compare |
| no stress control | McCas_formate_complete no stress control | -0.9 | -3.1 | compare |
| nitrogen source | Formate N-free with 2mM Adenosine | -0.9 | -3.2 | compare |
| stress | Formate 100 mM hypophosphite | -0.8 | -3.5 | compare |
| stress | McCas_formate_complete Ticarcillin 12.5 mM | -0.8 | -1.7 | compare |
| nutrient t2 | Formate McCas, 2.5g/L bicarb, 200 mM MOPs, 20 psi N2CO2, SO4 & Vitamin FREE | -0.7 | -2.0 | compare |
| stress | McCas_formate_complete Irgasan 0.0125 mM | -0.7 | -2.5 | compare |
| stress | McCas_formate_complete 2,2-dibromo-2-cyanoacetamide 0.00833333333333333 mM | -0.7 | -1.5 | compare |
| nutrient t2 | Formate McCas, 2.5g/L bicarb, 200 mM MOPs, 20 psi N2CO2, SO4 Vitamin & Casamino Acid FREE | -0.7 | -2.9 | compare |
| nutrient t2 | Formate McCas, 2.5g/L bicarb, 200 mM MOPs, 20 psi N2CO2, SO4 & Vitamin FREE | -0.6 | -1.7 | compare |
| stress | McCas_formate_complete Sulfaquinoxaline 0.1 mM | -0.6 | -1.9 | compare |
| stress | McCas_formate_complete sodium bromide 125 mM | -0.5 | -1.3 | compare |
| stress | McCas_formate_complete Polymyxin B sulfate 0.05 mM | -0.5 | -1.5 | compare |
| nutrient t2 | H2 McCas, 2.5g/L bicarb, 200 mM MOPs, 40 psi H2CO2, SO4 Vitamin & Casamino Acid FREE | -0.5 | -1.4 | compare |
| stress | McCas_formate_complete 3-nitroxypropanol 0.00208333333333333 mM | -0.5 | -1.9 | compare |
| stress | McCas_formate_complete hypophosphite 62.5 mM | -0.5 | -1.4 | compare |
| stress | McCas_formate_complete Fluorophosphate 31.25 mM | -0.5 | -1.7 | compare |
| stress | McCas_formate_complete Chlorite 0.3125 mM | -0.5 | -2.0 | compare |
| nitrogen source | H2 N-free with 2mM Adenosine | +0.9 | +1.5 | compare |
| nitrogen source | N2 fixation, H2 media | +1.0 | +1.5 | compare |