methionine--tRNA ligase
SEED: Methionyl-tRNA synthetase (EC 6.1.1.10)
KEGG: methionyl-tRNA synthetase
Top 20 experiments with the strongest phenotypes (|fitness| ≥ 1.7)
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| group | condition | fitness | t score | |
|---|
| nutrient t1 | formate McAA thiamine dropout | -2.6 | -4.0 | compare |
| nutrient t2 | Formate McCas, 2.5g/L bicarb, 200 mM MOPs, 20 psi N2CO2, SO4 & Vitamin FREE | -2.6 | -3.9 | compare |
| stress | McCas_formate_complete Phenazine methosulfate 0.0166666666666667 mM | -2.5 | -2.3 | compare |
| nutrient t2 | Formate McCas, 2.5g/L bicarb, 200 mM MOPs, 20 psi N2CO2, SO4 & Vitamin FREE | -2.4 | -3.7 | compare |
| nutrient t1 | formate McAA riboflavin dropout | -2.3 | -4.5 | compare |
| stress | McCas_formate_complete Nitrofurantoin 0.025 mM | -2.3 | -1.2 | compare |
| nutrient t2 | Formate McCas, 2.5g/L bicarb, 200 mM MOPs, 20 psi N2CO2, SO4 & Vitamin FREE | -2.1 | -3.7 | compare |
| iron | Iron limitation (0.2x), formate media | -1.9 | -2.6 | compare |
| nutrient t1 | formate McAA biotin dropout | -1.8 | -2.5 | compare |
| iron | Iron limitation (0.2x), formate media | -1.8 | -2.6 | compare |
| nutrient t1 | formate vitamin complete | -1.8 | -3.6 | compare |
| stress | McCas_formate_complete 2,2-dibromo-2-cyanoacetamide 0.00833333333333333 mM | -1.7 | -1.6 | compare |
| rich t2 | H2 McCas, 5g/L bicarb, 40 psi H2CO2 | -1.7 | -2.6 | compare |
| iron | Iron limitation (0.2x), formate media | -1.7 | -2.4 | compare |
| iron | control, 1x iron with casaminos and vitamins, formate media | -1.7 | -3.1 | compare |
| nutrient t1 | formate McAA pyroxidine HCl dropout | -1.7 | -3.0 | compare |
| nutrient t2 | Formate McCas, 2.5g/L bicarb, 200 mM MOPs, 20 psi N2CO2, SO4 & Casamino Acid FREE | -1.7 | -3.8 | compare |
| stress | McCas_formate_complete Chlorpromazine 0.0166666666666667 mM | -1.7 | -1.9 | compare |
| stress | McCas_formate_complete sodium nitrite 0.416666666666667 mM | -1.7 | -1.2 | compare |
| nitrogen source | H2 N-free with 2mM Adenosine | +2.5 | +2.1 | compare |