pyruvate dehydrogenase (acetyl-transferring), homodimeric type
SEED: Pyruvate dehydrogenase E1 component (EC 1.2.4.1)
KEGG: pyruvate dehydrogenase E1 component
Top 20 experiments with the strongest phenotypes (|fitness| ≥ 3.1)
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| group | condition | fitness | t score | |
|---|
| stress | Nickel (II) chloride 40 uM, aerobic | -4.3 | -2.9 | compare |
| stress | copper (II) chloride 5 uM, aerobic | -4.2 | -2.9 | compare |
| stress | Cadmium acetate 8 uM, aerobic | -4.0 | -2.8 | compare |
| stress | Nickel (II) chloride 40 uM, aerobic | -4.0 | -3.9 | compare |
| stress | Cobalt chloride 10 uM, aerobic | -4.0 | -2.8 | compare |
| stress | Cobalt chloride 10 uM, aerobic | -4.0 | -3.9 | compare |
| no stress control | Defined media control, aerobic | -3.9 | -3.8 | compare |
| stress | dichromate 5 uM, aerobic | -3.9 | -2.7 | compare |
| stress | copper (II) chloride 5 uM, aerobic | -3.8 | -3.7 | compare |
| no stress control | Defined media control, aerobic | -3.7 | -3.6 | compare |
| stress | dichromate 5 uM, aerobic | -3.7 | -3.6 | compare |
| stress | Cadmium acetate 8 uM, aerobic | -3.6 | -3.5 | compare |
| no stress control | Defined media control, aerobic | -3.6 | -4.2 | compare |
| stress | Nickel (II) chloride 40 uM, aerobic | -3.3 | -5.0 | compare |
| stress | Aluminum potassium sulfate dodecahydrate 1 mM, aerobic | -3.3 | -2.3 | compare |
| no stress control | Defined media control, aerobic | -3.1 | -2.2 | compare |
| stress | Cobalt chloride 10 uM, aerobic | -3.1 | -4.8 | compare |
| stress | Nickel (II) chloride 20 uM, anaerobic | -3.1 | -4.8 | compare |
| stress | dichromate 5 uM, aerobic | -3.1 | -4.2 | compare |
| survival | Survival; Treatment=FW300 (pH7.4) with 1.0 mM Glucose; TreatmentDuration=48hrs; Outgrowth=LBkan50 | +3.1 | +15.8 | compare |