bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE
SEED: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)
KEGG: phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase
Top 20 experiments with the strongest phenotypes (|fitness| ≥ 4.9)
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| group | condition | fitness | t score | |
|---|
| stress | Nickel (II) chloride 40 uM, aerobic | -6.2 | -9.5 | compare |
| stress | Cobalt chloride 10 uM, aerobic | -5.8 | -13.0 | compare |
| stress | Aluminum potassium sulfate dodecahydrate 1 mM, aerobic | -5.7 | -12.3 | compare |
| stress | Nickel (II) chloride 40 uM, aerobic | -5.6 | -13.1 | compare |
| stress | copper (II) chloride 5 uM, aerobic | -5.6 | -14.0 | compare |
| stress | copper (II) chloride 5 uM, aerobic | -5.5 | -13.7 | compare |
| no stress control | Defined media control, aerobic | -5.3 | -12.3 | compare |
| stress | Aluminum potassium sulfate dodecahydrate 1 mM, aerobic | -5.3 | -13.6 | compare |
| stress | Cobalt chloride 10 uM, aerobic | -5.3 | -12.7 | compare |
| stress | Uranyl Acetate Dihydrate 200 uM, aerobic | -5.2 | -12.2 | compare |
| carbon source | Ying_Nucleobase14 rep A; time point 2 | -5.2 | -3.6 | compare |
| no stress control | Defined media control, aerobic | -5.1 | -14.1 | compare |
| stress | dichromate 5 uM, aerobic | -5.1 | -12.4 | compare |
| no stress control | Defined media control, aerobic | -5.1 | -13.9 | compare |
| stress | copper (II) chloride 5 uM, aerobic | -5.1 | -14.6 | compare |
| stress | Aluminum potassium sulfate dodecahydrate 1 mM, aerobic | -5.0 | -14.2 | compare |
| carbon source | Ying_sugar7 rep B; time point 2 | -5.0 | -4.8 | compare |
| carbon source | Ying_Nucleobase14 rep C; time point 2 | -5.0 | -6.8 | compare |
| carbon source | Ying_sugar7 rep A; time point 2 | -4.9 | -5.9 | compare |
| carbon source | Ying_Nucleobase14 rep B; time point 3 | -4.9 | -3.4 | compare |