Fitness data for CCNA_00193 in Caulobacter crescentus NA1000

3-isopropylmalate dehydrogenase
SEED: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
KEGG: 3-isopropylmalate dehydrogenase

All 313 fitness values, sorted by group and condition


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group condition fitness t score  
carbon source a-Cyclodextrin (C) -4.4 -13.3 compare
a-Cyclodextrin (C) -4.7 -11.0 compare
a-Cyclodextrin (C) -4.7 -11.4 compare
Beta-Lactose (C) -2.5 -13.1 compare
Beta-Lactose (C) -2.4 -13.3 compare
Beta-Lactose (C) -2.6 -13.9 compare
D-Cellobiose (C) -3.9 -16.5 compare
D-Cellobiose (C) -3.5 -15.5 compare
D-Cellobiose (C) -3.8 -17.0 compare
D-Glucose (C) -3.9 -16.6 compare
D-Glucose (C) -3.8 -16.5 compare
D-Glucose (C) -4.2 -17.6 compare
D-Maltose (C) -3.0 -15.8 compare
D-Maltose (C) -2.9 -15.0 compare
D-Maltose (C) -4.2 -17.9 compare
D-Mannose (C) -3.3 -12.3 compare
D-Mannose (C) -3.0 -13.3 compare
D-Mannose (C) -2.2 -12.7 compare
D-Raffinose (C) -2.2 -12.1 compare
D-Raffinose (C) -1.8 -11.3 compare
D-Raffinose (C) -1.3 -9.2 compare
D-Salicin (C) -1.9 -10.6 compare
D-Salicin (C) -1.4 -9.2 compare
D-Salicin (C) -2.5 -11.9 compare
D-Xylose (C) -3.9 -15.7 compare
D-Xylose (C) -2.7 -14.1 compare
D-Xylose (C) -4.0 -16.1 compare
L-Alanine (C) -3.7 -18.5 compare
L-Alanine (C) -2.7 -14.0 compare
L-Alanine (C) -3.7 -15.6 compare
L-Glutamic (C) -3.8 -16.9 compare
L-Glutamic (C) -2.4 -13.1 compare
L-Glutamic (C) -1.1 -6.9 compare
L-Proline (C) -3.0 -14.9 compare
L-Proline (C) -3.7 -16.6 compare
L-Proline (C) -2.4 -13.7 compare
m-Inositol (C) -2.8 -13.8 compare
m-Inositol (C) -3.0 -14.4 compare
m-Inositol (C) -1.9 -9.9 compare
NAG (C) -3.8 -16.4 compare
NAG (C) -2.4 -13.7 compare
NAG (C) -4.7 -12.5 compare
m5g Growth in M5G -5.7 -20.1 compare
Growth in M5G -5.8 -18.7 compare
Growth in M5G -6.4 -16.7 compare
Growth in M5G -6.4 -17.4 compare
Growth in M5G -6.4 -16.6 compare
Growth in M5G -6.1 -18.8 compare
nitrogen source Adenosine (N) -2.8 -10.2 compare
Adenosine (N) -1.6 -8.8 compare
Ammonium chloride (N) -4.5 -15.6 compare
Ammonium chloride (N) -4.2 -16.0 compare
Casamino Acids (N) -0.2 -1.6 compare
Casamino Acids (N) +0.0 +0.1 compare
Cytidine (N) -2.5 -14.3 compare
Cytidine (N) -0.5 -3.2 compare
D-Glucosamine Hydrochloride (N) -3.7 -16.9 compare
D-Glucosamine Hydrochloride (N) -3.6 -17.2 compare
Glucuronamide (N) -2.5 -12.2 compare
Glucuronamide (N) -1.5 -10.0 compare
Inosine (N) -1.9 -12.4 compare
Inosine (N) -2.1 -11.6 compare
L-Alanine (N) -5.1 -14.1 compare
L-Alanine (N) -4.0 -14.1 compare
L-Arginine (N) -4.9 -15.2 compare
L-Arginine (N) -3.6 -14.7 compare
L-Asparagine (N) -3.2 -14.0 compare
L-Asparagine (N) -2.3 -12.2 compare
L-aspartic (N) -3.8 -15.6 compare
L-aspartic (N) -4.4 -15.7 compare
L-Citrulline (N) -0.5 -2.8 compare
L-Citrulline (N) -0.3 -2.1 compare
L-Glutamic (N) -4.0 -16.5 compare
L-Glutamic (N) -2.9 -16.0 compare
L-Isoleucine (N) -0.1 -0.9 compare
L-Isoleucine (N) -0.7 -4.1 compare
L-Leucine (N) +0.1 +0.7 compare
L-Leucine (N) +0.2 +1.0 compare
L-Phenylalanine (N) -2.0 -9.8 compare
L-Phenylalanine (N) -2.2 -10.1 compare
L-Proline (N) -3.4 -16.1 compare
L-Proline (N) -4.1 -16.4 compare
L-Tryptophan (N) -5.2 -14.1 compare
L-Tryptophan (N) -4.6 -15.0 compare
L-Valine (N) -0.0 -0.1 compare
L-Valine (N) +0.2 +1.1 compare
N-Acetyl-D-glucosamine (N) -0.2 -1.1 compare
N-Acetyl-D-glucosamine (N) -0.3 -1.9 compare
Putrescine (N) -4.5 -14.9 compare
Putrescine (N) -3.8 -15.4 compare
nitrate (N) -2.7 -13.0 compare
nitrate (N) -4.7 -11.5 compare
Urea (N) -0.9 -4.8 compare
Urea (N) -1.0 -6.5 compare
no stress control PYE no stress control +0.0 +0.3 compare
PYE no stress control +0.0 +0.2 compare
PYE no stress control +0.1 +0.5 compare
pH PYE pH6 copy A +0.2 +1.1 compare
PYE pH6 copy B +0.2 +1.4 compare
pye PYE +0.2 +1.8 compare
PYE +0.1 +0.9 compare
PYE +0.2 +1.3 compare
PYE +0.2 +1.7 compare
PYE +0.3 +1.9 compare
PYE -0.1 -0.5 compare
PYE +0.1 +0.8 compare
PYE +0.2 +1.6 compare
PYE +0.0 +0.2 compare
PYE +0.0 +0.2 compare
stress PYE with Aluminum chloride 1.25 mM +0.2 +1.4 compare
PYE with Aluminum chloride 1.25 mM +0.2 +1.5 compare
PYE with Benzalkonium Chloride 0.0001 mg/ml +0.1 +0.8 compare
PYE with Benzalkonium Chloride 0.0001 mg/ml +0.3 +1.8 compare
PYE with Benzethonium chloride 0.001 mM +0.2 +1.3 compare
PYE with Benzethonium chloride 0.001 mM +0.3 +2.0 compare
PYE with benzoic 0.2 mg/ml +0.2 +1.5 compare
PYE with benzoic 0.2 mg/ml +0.7 +4.6 compare
PYE with Carbenicillin 0.1 mg/ml +0.2 +1.6 compare
PYE with Carbenicillin 0.1 mg/ml +0.3 +1.7 compare
PYE with Carbenicillin 0.25 mg/ml +0.4 +2.4 compare
PYE with Carbenicillin 0.25 mg/ml +0.3 +2.3 compare
PYE with CHIR-090 1 ug/mL -0.0 -0.1 compare
PYE with CHIR-090 1 ug/mL +0.0 +0.2 compare
PYE with CHIR-090 1 ug/mL -0.0 -0.3 compare
PYE with CHIR-090 2 ug/mL +0.2 +1.4 compare
PYE with CHIR-090 2 ug/mL +0.1 +0.6 compare
PYE with CHIR-090 2 ug/mL +0.0 +0.4 compare
PYE with CHIR-090 4 ug/mL +0.1 +0.5 compare
PYE with CHIR-090 4 ug/mL -0.1 -0.9 compare
PYE with CHIR-090 4 ug/mL -0.0 -0.1 compare
PYE with Chloramphenicol 0.0001 mg/ml +0.3 +2.0 compare
PYE with Chloramphenicol 0.0001 mg/ml +0.3 +2.0 compare
PYE with Chloramphenicol 0.0005 mg/ml +0.3 +1.7 compare
PYE with Chloramphenicol 0.0005 mg/ml +0.1 +0.7 compare
PYE with Cisplatin 0.0025 mg/ml +0.1 +0.4 compare
PYE with Cisplatin 0.0025 mg/ml +0.2 +1.5 compare
PYE with Cisplatin 0.005 mg/ml +0.2 +1.4 compare
PYE with Cisplatin 0.005 mg/ml +0.1 +0.4 compare
PYE with Cobalt chloride 0.04 mM +0.3 +2.5 compare
PYE with Cobalt chloride 0.04 mM +0.3 +1.7 compare
PYE with Cobalt chloride 0.08 mM +0.1 +0.6 compare
PYE with Cobalt chloride 0.08 mM +0.1 +0.4 compare
PYE with copper (II) chloride 0.25 mM +0.4 +2.6 compare
PYE with copper (II) chloride 0.25 mM +0.3 +1.7 compare
PYE with Dimethyl Sulfoxide 5 vol% +0.3 +2.0 compare
PYE with Dimethyl Sulfoxide 5 vol% +0.4 +2.7 compare
PYE with Dimethyl Sulfoxide 7.5 vol% +0.4 +2.7 compare
PYE with Dimethyl Sulfoxide 7.5 vol% +0.4 +2.4 compare
PYE with Doxycycline hyclate 0.0001 mg/ml +0.2 +1.4 compare
PYE with Doxycycline hyclate 0.0001 mg/ml +0.2 +1.5 compare
PYE with Gentamicin 0.0005 mg/ml +0.5 +3.0 compare
PYE with Gentamicin 0.0005 mg/ml +0.3 +2.0 compare
PYE with A22 0.005 mg/ml +0.2 +1.4 compare
PYE with A22 0.005 mg/ml +0.2 +1.3 compare
PYE with Nalidixic 0.03 mg/ml +0.3 +2.0 compare
PYE with Nalidixic 0.03 mg/ml +0.3 +2.1 compare
PYE with Nalidixic 0.06 mg/ml +0.2 +0.9 compare
PYE with Nalidixic 0.06 mg/ml +0.3 +1.7 compare
PYE with Nickel (II) chloride 0.15 mM +0.1 +1.1 compare
PYE with Nickel (II) chloride 0.15 mM +0.1 +0.9 compare
PYE with Nickel (II) chloride 0.3 mM +0.1 +0.4 compare
PYE with Nickel (II) chloride 0.3 mM -0.1 -0.7 compare
PYE with Paraquat dichloride 0.015 mg/ml +0.2 +1.0 compare
PYE with Paraquat dichloride 0.015 mg/ml +0.3 +1.7 compare
PYE with Paraquat dichloride 0.03 mg/ml +0.1 +0.7 compare
PYE with Paraquat dichloride 0.03 mg/ml +0.4 +2.6 compare
PYE with Phosphomycin 0.005 mg/ml +0.4 +2.1 compare
PYE with Phosphomycin 0.005 mg/ml +0.1 +0.5 compare
PYE with Polymyxin B sulfate 0.005 mg/ml +0.4 +2.2 compare
PYE with Polymyxin B sulfate 0.005 mg/ml +0.4 +2.6 compare
PYE with Sisomicin 0.004 mg/ml +0.2 +1.2 compare
PYE with Sisomicin 0.004 mg/ml +0.3 +2.4 compare
PYE with Chlorate 40 mM +0.0 +0.0 compare
PYE with Chlorate 40 mM +0.2 +1.8 compare
PYE with Chloride 100 mM +0.3 +1.7 compare
PYE with Chloride 100 mM +0.4 +2.6 compare
PYE with Chlorite 0.5 mM +0.3 +2.1 compare
PYE with Chlorite 0.5 mM +0.2 +1.7 compare
PYE with sodium fluoride 7.5 mM -0.0 -0.0 compare
PYE with sodium fluoride 7.5 mM +0.0 +0.1 compare
PYE with sodium fluoride 15 mM +0.0 +0.1 compare
PYE with sodium fluoride 15 mM -0.0 -0.0 compare
PYE with sodium fluoride 30 mM +0.2 +1.0 compare
PYE with sodium fluoride 30 mM +0.3 +2.1 compare
PYE with nitrate 100 mM +0.3 +1.7 compare
PYE with nitrate 100 mM +0.3 +2.0 compare
PYE with nitrite 1.25 mM +0.2 +1.6 compare
PYE with nitrite 1.25 mM +0.1 +0.9 compare
PYE with nitrite 2.5 mM +0.4 +3.2 compare
PYE with nitrite 2.5 mM +0.1 +0.9 compare
PYE with nitrite 5 mM +0.6 +3.4 compare
PYE with nitrite 5 mM +0.6 +3.6 compare
PYE with perchlorate 25 mM +0.1 +0.5 compare
PYE with perchlorate 25 mM +0.2 +1.6 compare
PYE with perchlorate 50 mM +0.2 +1.5 compare
PYE with perchlorate 50 mM +0.2 +1.2 compare
PYE with Spectinomycin 0.025 mg/ml +0.3 +1.7 compare
PYE with Spectinomycin 0.025 mg/ml +0.3 +2.5 compare
PYE with Spectinomycin 0.08 mg/ml +0.3 +1.9 compare
PYE with Spectinomycin 0.08 mg/ml +0.1 +0.4 compare
24 hours of 100ug/mL streptomycin treatment after 3 hour phosphate starvation in M5G -6.3 -17.8 compare
48 hours of 100ug/mL streptomycin treatment after 3 hour phosphate starvation in M5G -6.9 -14.1 compare
24 hours of 100ug/mL streptomycin treatment after 3 hour phosphate starvation in M5G -6.4 -16.6 compare
48 hours of 100ug/mL streptomycin treatment after 3 hour phosphate starvation in M5G -6.5 -15.8 compare
24 hours of 100ug/mL streptomycin treatment after 3 hour phosphate starvation in M5G -6.8 -14.5 compare
48 hours of 100ug/mL streptomycin treatment after 3 hour phosphate starvation in M5G -7.0 -14.3 compare
24 hours of 100ug/mL streptomycin treatment after 3 hour phosphate starvation in M5G -6.3 -17.6 compare
48 hours of 100ug/mL streptomycin treatment after 3 hour phosphate starvation in M5G -6.9 -15.5 compare
24 hours of 100ug/mL streptomycin treatment after 3 hour phosphate starvation in M5G -6.6 -16.6 compare
48 hours of 100ug/mL streptomycin treatment after 3 hour phosphate starvation in M5G -7.6 -7.4 compare
24 hours of 100ug/mL streptomycin treatment after 3 hour phosphate starvation in M5G -6.8 -14.5 compare
48 hours of 100ug/mL streptomycin treatment after 3 hour phosphate starvation in M5G -7.0 -12.6 compare
PYE with Tetracycline 0.00005 mg/ml +0.2 +1.1 compare
PYE with Tetracycline 0.00005 mg/ml +0.1 +0.4 compare
PYE with Tetracycline 0.0001 mg/ml +0.3 +2.4 compare
PYE with Tetracycline 0.0001 mg/ml +0.2 +1.4 compare
PYE with Thallium(I) acetate 0.002 mg/ml +0.1 +1.0 compare
PYE with Thallium(I) acetate 0.002 mg/ml +0.1 +0.9 compare
PYE with Thallium(I) acetate 0.004 mg/ml +0.3 +1.6 compare
PYE with Thallium(I) acetate 0.004 mg/ml +0.1 +0.7 compare
PYE with Vancomycin 0.007 mg/ml +0.1 +0.7 compare
PYE with Vancomycin 0.007 mg/ml +0.1 +0.7 compare
survival PYE 0.5x 25C survival rep1 12 days -1.2 -8.7 compare
PYE 0.5x 25C survival rep1 28 days -1.2 -7.0 compare
PYE 0.5x 25C survival rep2 12 days -1.0 -7.1 compare
PYE 0.5x 25C survival rep2 28 days -0.7 -3.9 compare
PYE 0.5x 25C survival rep3 12 days -1.0 -6.7 compare
PYE 0.5x 25C survival rep3 28 days -0.8 -4.7 compare
PYE 0.5x 30C survival rep1 12 days -1.1 -7.4 compare
PYE 0.5x 30C survival rep1 28 days +0.4 +2.5 compare
PYE 0.5x 30C survival rep2 12 days -1.1 -7.7 compare
PYE 0.5x 30C survival rep2 28 days +0.2 +1.6 compare
PYE 0.5x 30C survival rep3 12 days -1.0 -6.6 compare
PYE 0.5x 30C survival rep3 28 days -0.5 -2.7 compare
PYE 0.5x 4C survival rep1 12 days -0.0 -0.3 compare
PYE 0.5x 4C survival rep1 28 days +0.1 +0.6 compare
PYE 0.5x 4C survival rep1 58 days +0.3 +1.6 compare
PYE 0.5x 4C survival rep2 12 days -0.1 -0.5 compare
PYE 0.5x 4C survival rep2 28 days +0.4 +2.5 compare
PYE 0.5x 4C survival rep2 58 days +0.6 +4.2 compare
PYE 0.5x 4C survival rep3 12 days +0.1 +1.0 compare
PYE 0.5x 4C survival rep3 28 days +0.3 +1.9 compare
PYE 0.5x 4C survival rep3 58 days +0.4 +2.3 compare
PYE 25C survival rep1 12 days -1.9 -11.7 compare
PYE 25C survival rep1 28 days -0.4 -2.4 compare
PYE 25C survival rep2 12 days -2.4 -14.2 compare
PYE 25C survival rep2 28 days -0.3 -1.3 compare
PYE 25C survival rep3 28 days -0.6 -3.4 compare
PYE 30C survival rep1 12 days -2.0 -11.2 compare
PYE 30C survival rep2 12 days -1.8 -10.2 compare
PYE 30C survival rep2 28 days -1.1 -5.9 compare
PYE 30C survival rep3 12 days -2.1 -13.3 compare
PYE 30C survival rep3 28 days +0.2 +1.9 compare
PYE 4C survival rep1 12 days -0.1 -0.7 compare
PYE 4C survival rep1 28 days +0.3 +1.5 compare
PYE 4C survival rep1 58 days +0.4 +2.8 compare
PYE 4C survival rep2 12 days +0.1 +0.8 compare
PYE 4C survival rep2 28 days +0.3 +1.8 compare
PYE 4C survival rep2 58 days +0.7 +4.9 compare
PYE 4C survival rep3 12 days +0.0 +0.3 compare
PYE 4C survival rep3 28 days +0.2 +1.5 compare
PYE 4C survival rep3 58 days +0.3 +2.0 compare
PYE recovery after M5G phosphate starvation and 48hr streptomycin treatment in 2L flask -5.8 -20.1 compare
PYE recovery after M5G phosphate starvation and 48hr streptomycin treatment in 2L flask -5.7 -12.8 compare
PYE recovery after M5G phosphate starvation and 48hr streptomycin treatment in 96 well block -5.8 -20.0 compare
PYE recovery after M5G phosphate starvation and 48hr streptomycin treatment in 96 well block -6.0 -19.3 compare
PYE recovery after M5G phosphate starvation and 48hr streptomycin treatment in 96 well block -6.1 -17.1 compare
PYE recovery after M5G phosphate starvation and 48hr streptomycin treatment in 96 well block -4.8 -9.3 compare
PYE_noCalcium 25C survival rep1 12 days -3.4 -17.6 compare
PYE_noCalcium 25C survival rep1 28 days -0.8 -4.5 compare
PYE_noCalcium 25C survival rep2 12 days -3.0 -15.4 compare
PYE_noCalcium 25C survival rep2 28 days -0.2 -1.3 compare
PYE_noCalcium 25C survival rep3 12 days -3.4 -16.4 compare
PYE_noCalcium 25C survival rep3 28 days -0.7 -4.2 compare
PYE_noCalcium 30C survival rep2 12 days -2.6 -14.5 compare
PYE_noCalcium 30C survival rep2 28 days -1.4 -6.3 compare
PYE_noCalcium 30C survival rep3 12 days -2.1 -13.5 compare
PYE_noCalcium 4C survival rep1 12 days -0.0 -0.1 compare
PYE_noCalcium 4C survival rep1 28 days +0.2 +1.2 compare
PYE_noCalcium 4C survival rep1 58 days +0.1 +0.5 compare
PYE_noCalcium 4C survival rep2 12 days -0.0 -0.3 compare
PYE_noCalcium 4C survival rep2 28 days +0.1 +0.5 compare
PYE_noCalcium 4C survival rep2 58 days +0.0 +0.2 compare
PYE_noCalcium 4C survival rep3 12 days -0.0 -0.1 compare
PYE_noCalcium 4C survival rep3 28 days -0.1 -0.4 compare
PYE_noCalcium 4C survival rep3 58 days -0.1 -0.8 compare
temperature PYE 0.5x 25C +0.1 +1.1 compare
PYE 0.5x 25C +0.1 +0.4 compare
PYE 0.5x 25C +0.0 +0.1 compare
PYE 0.5x 30C +0.1 +1.1 compare
PYE 0.5x 30C +0.1 +0.5 compare
PYE 0.5x 30C +0.0 +0.0 compare
PYE 0.5x 4C +0.5 +3.1 compare
PYE 0.5x 4C +0.4 +2.1 compare
PYE 0.5x 4C +0.4 +2.6 compare
PYE 25C -0.0 -0.3 compare
PYE 25C +0.2 +1.3 compare
PYE 25C +0.1 +0.4 compare
PYE 30C +0.2 +1.7 compare
PYE 30C +0.1 +0.9 compare
PYE 30C +0.1 +0.7 compare
PYE 4C +0.6 +4.2 compare
PYE 4C +0.4 +2.3 compare
PYE 4C +0.4 +2.8 compare
PYE_noCalcium 25C +0.2 +1.3 compare
PYE_noCalcium 25C +0.3 +2.2 compare
PYE_noCalcium 25C +0.2 +1.3 compare
PYE_noCalcium 30C +0.1 +0.7 compare
PYE_noCalcium 30C +0.1 +1.1 compare
PYE_noCalcium 30C +0.1 +1.0 compare
PYE_noCalcium 4C +0.3 +2.2 compare
PYE_noCalcium 4C +0.1 +0.4 compare
PYE_noCalcium 4C +0.4 +2.3 compare