Pairwise Alignments
Query, 559 a.a., FIGfam138462: Acyl-CoA synthetase, AMP-(fatty) acid ligase / (3R)-hydroxymyristoyl-[ACP] dehydratase (EC 4.2.1.-) from Pseudomonas fluorescens GW456-L13
Subject, 4161 a.a., non-ribosomal peptide synthetase from Pseudomonas fluorescens FW300-N2C3
Score = 75.1 bits (183), Expect = 5e-17
Identities = 107/407 (26%), Positives = 173/407 (42%), Gaps = 72/407 (17%)
Query: 89 GDVDLWLSDQPDDAHLGDLQQPPLSAAALDLDNCRLSLCTSGSSGEPKRIEKNLRQLANE 148
GD D WLSD D PP A A N + TSGS+G+PK + L N
Sbjct: 1740 GDDD-WLSDHSTD-------NPPARAVA---QNLAYVIYTSGSTGKPKGAGNSHGALTNR 1788
Query: 149 VEALEQLWGADLGPACIIGSVATQHIYGLLFRVLWPLCAGRPFLRRQLAFPEDLQRASR- 207
+ ++Q +G + G + + + + + ++ WPL G +R +A P D + +
Sbjct: 1789 LCWMQQAYGLEAGDSVLQKTPFSFDVS--VWEFFWPLMTG---VRLVVAAPGDHRDPQKL 1843
Query: 208 ----EYPAFTWVAS-PALLKRMGDNLDWPALSAVRRVFSSGGALPVEAAQSLHERLGQWP 262
E + T + P++L+ + + + + R+ SG ALPV+A Q + +L
Sbjct: 1844 VSLIERESITTLHFVPSMLQAFVLDANVSRCTCLTRIVCSGEALPVDAQQQVFAKLPNAR 1903
Query: 263 T-EIFGSSETG--GIAW------RQGAELWRPFADV-TLTQDSE---------GAL---- 299
++G +E W R + P A++ T D E G L
Sbjct: 1904 LYNLYGPTEAAIDVTHWTCRDEGRDAVPIGEPIANLMTYILDDELNPVPSGVNGELYLSG 1963
Query: 300 -----------------LIASPYLPVGQIEHTADSARIAIDGRFELLGRLDRIVKLEEKR 342
+ASP++ ++ T D AR DG + +GR+D VK+ R
Sbjct: 1964 QGLARGYHRRPELTAERFVASPFVAGERLYRTGDLARYRPDGVIDYVGRIDHQVKVRGFR 2023
Query: 343 ISLPMLEQALTTHEWVIEARLGVVQENRASLGALL---VLSEAGLHVLRNHGRRSLTEQL 399
I L +E L H V EA + V Q++R+ G +L V+++AG R +L L
Sbjct: 2024 IELGEIEARLLEHAAVREA-VVVAQDSRS--GKVLSGYVVAQAGEASDWPLLREALLAHL 2080
Query: 400 RQHLSQHCEALALPRRWRLLRQLPLNAQGKLPQADVDALLLAPRPKA 446
R +L +H +P L +PL+ GKL + + A LA R +A
Sbjct: 2081 RLNLPEH----MVPTHLTRLEHMPLSPNGKLDRKALPAPDLAERQEA 2123
Score = 51.6 bits (122), Expect = 6e-10
Identities = 93/381 (24%), Positives = 145/381 (38%), Gaps = 61/381 (16%)
Query: 114 AAALDLDNCRLSLCTSGSSGEPKRIEKNLRQLANEVEALEQLWGADLGPACIIGSVATQH 173
A LD ++ ++ TSGS+G+PK + L N V ++ Q G + + +
Sbjct: 677 APRLDAEHLAYAIYTSGSTGKPKGVMVRHGALTNFVASMAQAPGMTAQDRALSLTTFSFD 736
Query: 174 IYGLLFRVLWPLCAGRPFLRRQLAFPED----LQRASREYPAFTWVASPALLKRMGDNLD 229
I+GL V PL G + +D L + E A+P+ + + DN
Sbjct: 737 IFGLEIYV--PLMVGACIVLTGQHVAQDPYAVLALIAAEQVNVVQ-ATPSTWRMLLDNEH 793
Query: 230 WPALSAVRRVFSSGGALPVEAAQSLHERLGQWPTEIFGSSETGGIAWR-------QGAEL 282
L + G ALP E A + LG ++G +ET W Q A+
Sbjct: 794 AQGLRGCK-CLCGGEALPQELAVRMLA-LGGEVWNLYGPTET--TIWSALHPLQTQAAQP 849
Query: 283 WR--PFADVTL----------TQDSEGALLIAS---------------------PYLPVG 309
W P + L G LLI P++
Sbjct: 850 WLGGPIDNTALYIVGADLMPVPYGVAGELLIGGQGLARGYFQRPALTAERFVPHPFVAGE 909
Query: 310 QIEHTADSARIAIDGRFELLGRLDRIVKLEEKRISLPMLEQALTTHEWVIEARLGVVQEN 369
++ T D AR DG E LGR+D VK+ RI L +E L + V EA V+ +
Sbjct: 910 RLYRTGDLARQRADGILEYLGRIDHQVKIRGFRIELGEIEARLLEQDSVREA--AVLAQE 967
Query: 370 RASLGALL--VLSEAGLHVLRNHGRRSLTEQLRQHLSQHCEALALPRRWRLLRQLPLNAQ 427
A AL+ ++ A L+ L + +L + L L + +P +L + PL
Sbjct: 968 AAGGQALVAYIVPTAELNDLDAGAQGALRDSLTARLKVNLPDYMVPAHMVVLPRFPLTPN 1027
Query: 428 GKLPQADVDALLLAPRPKAPE 448
GKL + + P+P A +
Sbjct: 1028 GKLDRKQL------PKPDASQ 1042
Score = 36.2 bits (82), Expect = 3e-05
Identities = 46/191 (24%), Positives = 78/191 (40%), Gaps = 23/191 (12%)
Query: 243 GGALPVEAAQSLHERLGQWPTEIFGSSETGGIAWRQGAELWRPFADVTLTQDSEGALLIA 302
G A+ A L + L P I G GG +G RP D +
Sbjct: 3443 GRAVGERALYVLDDNLNPLPPGIAGELYIGGAGIARGYHR-RP--------DLSAERFVP 3493
Query: 303 SPY-LPVGQIEHTADSARIAIDGRFELLGRLDRIVKLEEKRISLPMLEQALTTHEWVIEA 361
P+ P ++ + D R +DG + +GR+D +K+ RI L +E +L + V +A
Sbjct: 3494 DPFGQPGDRLYRSGDLVRQRVDGVLDYVGRIDHQIKVRGFRIELGEVEASLRQLDDVSDA 3553
Query: 362 RLGVVQENRASLGALL--VLSEAGLHVLRNHGRRSLTEQLRQHLSQHCEALALPRRWRLL 419
V+ + AS L+ V++ G+ ++ ++L+ L +P + L
Sbjct: 3554 L--VIARDSASGKQLIGYVVTPDGV---------AIGDRLKAELRAQLPDYMVPAQVICL 3602
Query: 420 RQLPLNAQGKL 430
LP+ GKL
Sbjct: 3603 EALPVTPNGKL 3613