Pairwise Alignments

Query, 1230 a.a., 5-methyltetrahydrofolate--homocysteine methyltransferase from Pseudomonas stutzeri RCH2

Subject, 1235 a.a., cobalamin-dependent methionine synthase from Pseudomonas putida KT2440

 Score = 2180 bits (5648), Expect = 0.0
 Identities = 1083/1235 (87%), Positives = 1156/1235 (93%), Gaps = 5/1235 (0%)

Query: 1    MSTRSSRLQALQQALKERILILDGGMGTMIQSYKLEEEDYRGTRFADWPQDVKGNNDLLL 60
            MS RS+RLQALQ ALKERILILDGGMGTMIQSY+LEE DYRGTRFADWP DVKGNNDLLL
Sbjct: 1    MSDRSARLQALQNALKERILILDGGMGTMIQSYRLEEHDYRGTRFADWPSDVKGNNDLLL 60

Query: 61   LSRPDIIQAIEKAYLDAGADILETNTFNATRVSQADYGMEELVYELNVEGARLAREVADA 120
            LSRPD+I AIEKAYLDAGADILETNTFNAT++SQADYGME LVYELNVEGAR+AR+VADA
Sbjct: 61   LSRPDVIAAIEKAYLDAGADILETNTFNATQISQADYGMESLVYELNVEGARIARQVADA 120

Query: 121  KTAETPDRPRFVAGVLGPTSRTCSISPDVNNPGYRNVTFDLLVENYVEATRGLIEGGADL 180
            KT ETPD+PRFVAGVLGPTSRTCSISPDVN+PG+RNVTFD LVENY+EATRGLIEGGADL
Sbjct: 121  KTLETPDKPRFVAGVLGPTSRTCSISPDVNDPGFRNVTFDELVENYIEATRGLIEGGADL 180

Query: 181  ILIETIFDTLNAKAAIFAVQQVFEDEGVELPIMISGTITDASGRTLSGQTTEAFWNSVRH 240
            ILIETIFDTLNAKAAIFAVQQVFED+ VELPIMISGTITDASGRTLSGQTTEAFWNSVRH
Sbjct: 181  ILIETIFDTLNAKAAIFAVQQVFEDDNVELPIMISGTITDASGRTLSGQTTEAFWNSVRH 240

Query: 241  AKPISVGLNCALGAKDLRPYLEELSSKAETFVSAHPNAGLPNAFGEYDESPAEMAAVVEE 300
            AKPISVGLNCALGAKDLRPYLEEL++KA+T VSAHPNAGLPNAFGEYDE+PAEMAAVVEE
Sbjct: 241  AKPISVGLNCALGAKDLRPYLEELATKADTHVSAHPNAGLPNAFGEYDETPAEMAAVVEE 300

Query: 301  FAASGFLNIIGGCCGTTPAHIQAIAEAVSKYPPRAIPDIPKACRLSGLEPFTIDRSSLFV 360
            FAASGFLNIIGGCCGTTP HIQAIAEAV+KY PR IP+I KACRLSGLEPFTIDR SLFV
Sbjct: 301  FAASGFLNIIGGCCGTTPGHIQAIAEAVAKYKPREIPEIAKACRLSGLEPFTIDRQSLFV 360

Query: 361  NVGERTNITGSAKFARLIREENYTEALEVALQQVEAGAQVIDINMDEGMLDSKAAMVTFL 420
            NVGERTNITGSAKFARLIREENYTEALEVALQQVEAGAQVIDINMDEGMLDS+AAMV FL
Sbjct: 361  NVGERTNITGSAKFARLIREENYTEALEVALQQVEAGAQVIDINMDEGMLDSQAAMVRFL 420

Query: 421  NLIAGEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISMKEGVEQFKQQAHLCKRYG 480
            NLIAGEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISMKEGVEQFK  A LCKRYG
Sbjct: 421  NLIAGEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISMKEGVEQFKHHARLCKRYG 480

Query: 481  AAVVVMAFDEAGQADTAARKREICKRSYDILVNEVGFPPEDIIFDPNIFAIATGIEEHNN 540
            AAVVVMAFDE GQADTAARK+EIC+RSYDILVNEVGFPPEDIIFDPNIFA+ATGIEEHNN
Sbjct: 481  AAVVVMAFDEVGQADTAARKKEICQRSYDILVNEVGFPPEDIIFDPNIFAVATGIEEHNN 540

Query: 541  YAVDFIEACAYIRDNLPYALTSGGVSNVSFSFRGNNPVREAIHSVFLFHAIKAGLTMGIV 600
            YAVDFIEACAYIRD+LP+AL+SGGVSNVSFSFRGNNPVREAIHSVFL+HAI+ GLTMGIV
Sbjct: 541  YAVDFIEACAYIRDHLPHALSSGGVSNVSFSFRGNNPVREAIHSVFLYHAIQNGLTMGIV 600

Query: 601  NAGQLEIYDEIPKELRDAVEDVVLNRSANGTEGLLELADKYKGDGSVKEAETEEWRSLPV 660
            NAGQLEIYDEIP +LR+ VEDVVLNR+ +GT+ LL +AD YKG G+ KE E EEWRSLPV
Sbjct: 601  NAGQLEIYDEIPAQLREKVEDVVLNRTPHGTDALLAIADDYKGGGATKEVENEEWRSLPV 660

Query: 661  DKRLEHALVKGITAFIVEDTEECRQQCKRPIEVIEGPLMSGMNVVGDLFGAGKMFLPQVV 720
            +KRLEHALVKGITAFIVEDTE CRQQC RPIEVIEGPLM+GMNVVGDLFGAGKMFLPQVV
Sbjct: 661  EKRLEHALVKGITAFIVEDTEACRQQCARPIEVIEGPLMNGMNVVGDLFGAGKMFLPQVV 720

Query: 721  KSARVMKQAVAHLIPFIEAEKGDKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNGYDVV 780
            KSARVMKQAVAHLIPFIEAEKGDKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNGYD+V
Sbjct: 721  KSARVMKQAVAHLIPFIEAEKGDKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNGYDIV 780

Query: 781  DMGVMVPAEKILQTAIAEKCDIIGLSGLITPSLDEMVHVAKEMQRQGFSLPLMIGGATTS 840
            D+GVMVPAEKILQTA  +KCDIIGLSGLITPSLDEMVHVA+EMQRQGF LPLMIGGATTS
Sbjct: 781  DLGVMVPAEKILQTAREQKCDIIGLSGLITPSLDEMVHVAREMQRQGFELPLMIGGATTS 840

Query: 841  KAHTAVKIDPQYHNDAVVYVTDASRAVGVATTLLSKELKPAFVEKTREEYAMIRERTANR 900
            KAHTAVKI+P+Y NDAV+YVTDASRAVGVAT LLSKELKP FVEKTR EY  +RERTANR
Sbjct: 841  KAHTAVKIEPKYSNDAVIYVTDASRAVGVATQLLSKELKPGFVEKTRLEYVDVRERTANR 900

Query: 901  SARTERLSYAQAVANKPQFDWASYTPVKPSFTGRQLLEDIDLRTLAEYIDWTPFFIAWDL 960
            SARTERLSYAQA+A KPQ+DWA Y P  PSFTG ++LEDIDLRTLAEYIDWTPFFI+WDL
Sbjct: 901  SARTERLSYAQAIAAKPQYDWAGYQPTAPSFTGVKVLEDIDLRTLAEYIDWTPFFISWDL 960

Query: 961  AGKYPRILEDEVVGEAATALFSDAQAMLNKLIDEKLIRARAVFGFWPANQVQDDDLEVYG 1020
            AGK+PRIL DEVVGEAATAL+ DA+ ML+KLIDEKLI ARAVFGFWPANQV DDD+EVYG
Sbjct: 961  AGKFPRILTDEVVGEAATALYKDAREMLDKLIDEKLISARAVFGFWPANQVDDDDIEVYG 1020

Query: 1021 DGGEKLATLHHLRQQIIKPDAKPNLSLADFVAPKDSGITDYVGGFICTAGIGAEELAKAY 1080
            + G+ LATLHHLRQQ IKPD KPN SLADFVAPKDSG+TDYVGGFI TAGIGAEE+AKAY
Sbjct: 1021 EDGQALATLHHLRQQTIKPDGKPNWSLADFVAPKDSGVTDYVGGFITTAGIGAEEVAKAY 1080

Query: 1081 QDKGDDYNSIMVKALADRLAEACAEWLHQQVRKQYWGYAKDEQLSNEELIREQYKGIRPA 1140
            QDKGDDY+SIMVKALADRLAEACAEWLH+QVRK++WGYA+DE L NE LI+EQY GIRPA
Sbjct: 1081 QDKGDDYSSIMVKALADRLAEACAEWLHEQVRKEHWGYARDEHLDNEALIKEQYSGIRPA 1140

Query: 1141 PGYPACPDHTEKGTLFQLLDADGI-----SQVTLTEHYAMLPTAAVSGWYFAHPEAQYFA 1195
            PGYPACPDHTEK TLF+LLD   I     S V LTEH+AM P AAVSGWYFAHP+A+YFA
Sbjct: 1141 PGYPACPDHTEKETLFRLLDGTAIGETGPSGVYLTEHFAMFPAAAVSGWYFAHPQAKYFA 1200

Query: 1196 VGKIDKDQVESYSQRKGEDIAVSERWLMPNLGYDN 1230
            VGK+DKDQ+E YS RKG+DI+VSERWL PNLGYD+
Sbjct: 1201 VGKVDKDQIERYSARKGQDISVSERWLAPNLGYDS 1235