Pairwise Alignments

Query, 508 a.a., Inosine-5'-monophosphate dehydrogenase from Xanthobacter sp. DMC5

Subject, 500 a.a., IMP dehydrogenase from Methanococcus maripaludis S2

 Score =  466 bits (1198), Expect = e-135
 Identities = 253/492 (51%), Positives = 340/492 (69%), Gaps = 16/492 (3%)

Query: 20  REALTFDDVLLTPGASEVMPGQVEITTQLTKTISLNMPIISAAMDTVTESRLAIAMAQAG 79
           + A TFDDVLL P  S V P   +++  +   + LN+PIISAAMDTV+E  LAIA+A+ G
Sbjct: 14  QRAYTFDDVLLVPNKSFVDPKTTDVSVDIAG-LKLNIPIISAAMDTVSEKDLAIALARRG 72

Query: 80  GIGVIHRNLSPEMQAEHVRQVKKYESGMVVNPVTIHPDQTLSDALDLMKRYSISGIPVVE 139
           GI VIHRN++ E Q +HV+ VK  E+ ++ + VT+ P  ++ DA  +M  Y++SG+PVV 
Sbjct: 73  GIAVIHRNMTVEEQLKHVKAVKMAENLVIRDVVTVEPSSSVLDAERIMYEYNVSGLPVVS 132

Query: 140 RGTGGIAGRLVGILTNRDVRFARDPAQRVAELMTKDRLVTVREGQVNQDEAKRLLHQYRI 199
                    LVGILT RD++F  D    V  +MTK+ ++ V E    ++   RL ++ +I
Sbjct: 133 ENK-----TLVGILTTRDLKFVPDKNVAVETVMTKE-VLHVHEDTPYEEILNRL-YENKI 185

Query: 200 EKLLVVDSDDR-CVGLITVKDIEKAVAYPSAAKDEQGRLRVAAATTVGEDGFERTERLID 258
           E+L ++D + +  +G++T++DI K   YP AA+D  G+L VAAA   G   FER E L+ 
Sbjct: 186 ERLPILDKNTKELLGMVTLRDILKRKKYPDAARDSDGKLVVAAAC--GPSDFERAEALVL 243

Query: 259 AGVDLVVVDTAHGHSRKVLDQVERIKKL--SNRTQILAGNIATSDGAKALIDAGADAVKV 316
           AGVD V +D AH H+ +V++ V+++K++    +T++  GNIAT + A+ LI AGADA+KV
Sbjct: 244 AGVDAVAIDCAHAHNMQVVENVKKLKEILKGTKTKLFVGNIATGEAAEDLIKAGADALKV 303

Query: 317 GIGPGSICTTRIVAGVGVPQLTAVMDAVEAALATGTPVVADGGIKFSGDLAKALAAGASA 376
           GIGPGSICTTR+VAGVGVPQLTAV +  E A   G PV+ADGGIK+SGD+AKA+AAGA+A
Sbjct: 304 GIGPGSICTTRVVAGVGVPQLTAVAEVAEVAKKYGVPVIADGGIKYSGDIAKAIAAGANA 363

Query: 377 AMVGSLLAGTDESPGEVFLFQGRSYKSYRGMGSVGAMARGS---ADRYFQAEVRDTLKLV 433
            MVGSLLAGT+E+PG +    GR YK YRGMGS+GAM   S   ADRYFQ+      KLV
Sbjct: 364 VMVGSLLAGTEEAPGSLMTINGRKYKQYRGMGSLGAMCGSSGNVADRYFQSGHMKHSKLV 423

Query: 434 PEGIEGQVAYKGPVGAVLHQLAGGLRAAMGYVGGSNLKEFRERARFVRISSAGLRESHVH 493
           PEGIEG V YKGP   +++QL GGLR++MGY G  NL E  E+ARFV I+ +G +ESH H
Sbjct: 424 PEGIEGAVPYKGPTSDIVYQLIGGLRSSMGYCGAQNLSEMHEKARFVIITQSGQKESHPH 483

Query: 494 DVTITRESPNYP 505
           DV IT E+PNYP
Sbjct: 484 DVLITNEAPNYP 495