Pairwise Alignments
Query, 767 a.a., mammalian cell entry protein from Pseudomonas simiae WCS417
Subject, 879 a.a., MCE family protein from Vibrio cholerae E7946 ATCC 55056
Score = 331 bits (849), Expect = 9e-95
Identities = 222/702 (31%), Positives = 361/702 (51%), Gaps = 43/702 (6%)
Query: 16 SAIWVLPLIALIIGGWLGWRAYSQQGIDIQVRFESGEGIQVNKTEVVYKGMPVGKVKALA 75
S +W+LP++ +I+ GWL ++A G+ IQ+ FE+ +G+ +T + Y+G+ VG V+ +
Sbjct: 22 SPLWILPIVTMILAGWLVFKAVHDAGVRIQIHFENAQGLIAGRTTIRYQGLEVGMVRDIK 81
Query: 76 LDDEGNNRGVIATIEMNKDVDQYLKTNTRFWLVKPSVSLAGITGLETLVSGNYIAASPG- 134
L + ++ + ++ + + L TRFW+VKP+ SL+G++GL+ LVSGNYIA PG
Sbjct: 82 LSEGLDS--IYVEADIYPEATKLLSNQTRFWMVKPTASLSGVSGLDALVSGNYIAIQPGS 139
Query: 135 ---DGEPTRKFKALSEEPPLSDAKPGLHLTVKADRLGSLNRGSPVFYKQIQVGQVKSYLL 191
+ PT+ ++AL P A+ GL +++KA LG ++ GS + YK+I +G+V SY L
Sbjct: 140 THQEDYPTQ-YQALDSAPSDLLAQRGLTISLKARDLGGISVGSQIVYKKIPIGEVFSYQL 198
Query: 192 SEDQSTVEIKVYIEPTYASLVRKHTRFWNASGISIDANLSGVKVRSESLSSIVAGGIAFA 251
+D +V I+ I+ Y ++ +RFWN SGI GV VR ESLS+++ G IA
Sbjct: 199 DDDAQSVIIQASIKEEYQHIINTESRFWNVSGIGASIGFEGVDVRLESLSALIGGSIAVD 258
Query: 252 TPENRKDSPPTDPSLPFRLYEDFDAAAAGIRVKVKLTDFEGLQAGRTPVMYKGIQVGSLK 311
+P+ K P + + FRLY D A GI V + L D + A P+MY+GI++G +
Sbjct: 259 SPDEGK---PVEQNAQFRLYRDLKTAGRGIAVSITLPDDNNISASGAPIMYRGIEIGQIT 315
Query: 312 TLKVDPDLSSANAELTLDPLAEDYLVQDTQFWVVKPSISLAGITGLEALVKGNYIAIRPG 371
L++ + S A + P D L Q +QF + + +SL G+ L LVKGNY+ + PG
Sbjct: 316 DLQLTENRKSIVASAAIQPAFSDMLNQGSQFVLEEAQVSLTGVENLTNLVKGNYLTLIPG 375
Query: 372 DKGTAPQREFVARAKAPPLDLRSPGLHMVLFTDNLGSLDVGSPILYKQVKVGSVQSYQFS 431
R F A K RS + L DN L+ G+PILY+ V VGSV +
Sbjct: 376 --AGERTRNFQAVRKNEFKYARSNSISFNLVADNSFGLEAGTPILYRGVAVGSVTAVNL- 432
Query: 432 RKNKQLVIGVHIEKEYENLVNGSTRFWNASGVTLTGGLTGGIQVKSESLASLMAGGIAFE 491
K + V I+++Y L+ RF+ +G G+ V L+ G I+F
Sbjct: 433 -KLDYVEFNVLIDEQYGALIRSQNRFY-VTGSAAAELTESGLSVSIPPAKQLLLGSISFA 490
Query: 492 TPEPNVPLKKRIPRFRLFADREAA-----NQHGT-LVTIKVDRADGMRPGTPVRFKGLDV 545
+ + PL+ ++RL++ + A NQ G+ +T+ + G+P+ ++ L V
Sbjct: 491 SEGSSTPLE----QYRLYSSQSLAELAKYNQSGSRSLTLFAHELPSINAGSPLLYRNLKV 546
Query: 546 GKIESVDLSADMQSVLLSARITQVADRIARAGSQFW-----VVKPEL-GL-MKTSNLETL 598
G I L+ + V + A I + + + FW +K + G+ +K + L+TL
Sbjct: 547 GSISGFTLTP--KGVQIEATIEKQYQHLLTPDTVFWNRSGVEIKASMDGVDVKAAPLQTL 604
Query: 599 VTGQY-IEVLPAAKN--AGPQKSFVALDQPPEAVHQEAGLSLTLSAARRGSLKEGVPVTY 655
+ G + LP +N K + D + G +TL+A +K G PV Y
Sbjct: 605 IRGGIAFDNLPGIENKVGSMWKLYSDYDHA-----RRYGEKITLTALGTLGVKVGTPVQY 659
Query: 656 REVTVGKVTGYELGQTADRVLIHILIEPKYAP-LVRSGSRFW 696
+ V +G+V +D V + IEP+YAP + + S+FW
Sbjct: 660 QGVQIGEVFEIIPDFESDFVKLAARIEPQYAPKIAKQNSQFW 701
Score = 305 bits (780), Expect = 9e-87
Identities = 218/755 (28%), Positives = 384/755 (50%), Gaps = 66/755 (8%)
Query: 38 SQQGIDIQVRFESGEGIQVNKTEVVYKGMPVGKVKALALDDEGNNRGVIATIEMNKDVDQ 97
+Q+G+ I ++ GI V +++VYK +P+G+V + LDD+ + VI + ++
Sbjct: 161 AQRGLTISLKARDLGGISVG-SQIVYKKIPIGEVFSYQLDDDAQS--VIIQASIKEEYQH 217
Query: 98 YLKTNTRFWLVKPSVSLAGITG-------LETLVSGNYIAASPGDGEPTRKFKALSEEPP 150
+ T +RFW V + G G L L+ G+ SP +G+P +
Sbjct: 218 IINTESRFWNVSGIGASIGFEGVDVRLESLSALIGGSIAVDSPDEGKPVEQNAQFRLYRD 277
Query: 151 LSDAKPGLHLTVKADRLGSLNR-GSPVFYKQIQVGQVKSYLLSEDQSTVEIKVYIEPTYA 209
L A G+ +++ +++ G+P+ Y+ I++GQ+ L+E++ ++ I+P ++
Sbjct: 278 LKTAGRGIAVSITLPDDNNISASGAPIMYRGIEIGQITDLQLTENRKSIVASAAIQPAFS 337
Query: 210 SLVRKHTRFWNASGISIDANLSGVKVRSESLSSIVAGGIAFATPENRKDSPPTDPSLPFR 269
++ + ++F +L+GV E+L+++V G P + T R
Sbjct: 338 DMLNQGSQFVLEEA---QVSLTGV----ENLTNLVKGNYLTLIPGAGER---TRNFQAVR 387
Query: 270 LYEDFDAAAAGIRVKVKLTDFEGLQAGRTPVMYKGIQVGSLKTLKVDPDLSSANAELTLD 329
E A + I + + GL+AG TP++Y+G+ VGS+ + + D N + +D
Sbjct: 388 KNEFKYARSNSISFNLVADNSFGLEAG-TPILYRGVAVGSVTAVNLKLDYVEFN--VLID 444
Query: 330 PLAEDYLVQDTQFWVVKPSISLAGITGLEALVKGNYIAIRPGDKGTAPQREFVARAKAPP 389
+ +F+V G E G ++I P + F + + P
Sbjct: 445 EQYGALIRSQNRFYVT-------GSAAAELTESGLSVSIPPAKQLLLGSISFASEGSSTP 497
Query: 390 LDL----------------RSPGLHMVLFTDNLGSLDVGSPILYKQVKVGSVQSYQFSRK 433
L+ +S + LF L S++ GSP+LY+ +KVGS+ + + K
Sbjct: 498 LEQYRLYSSQSLAELAKYNQSGSRSLTLFAHELPSINAGSPLLYRNLKVGSISGFTLTPK 557
Query: 434 NKQLVIGVHIEKEYENLVNGSTRFWNASGVTLTGGLTGGIQVKSESLASLMAGGIAFETP 493
Q I IEK+Y++L+ T FWN SGV + + G + VK+ L +L+ GGIAF+
Sbjct: 558 GVQ--IEATIEKQYQHLLTPDTVFWNRSGVEIKASMDG-VDVKAAPLQTLIRGGIAFD-- 612
Query: 494 EPNVP-LKKRI-PRFRLFADREAANQHGTLVTIKVDRADGMRPGTPVRFKGLDVGKIESV 551
N+P ++ ++ ++L++D + A ++G +T+ G++ GTPV+++G+ +G++ +
Sbjct: 613 --NLPGIENKVGSMWKLYSDYDHARRYGEKITLTALGTLGVKVGTPVQYQGVQIGEVFEI 670
Query: 552 DLSADMQSVLLSARIT-QVADRIARAGSQFWVVKPELGLMKTSNLETLVTGQYIEVLPAA 610
+ V L+ARI Q A +IA+ SQFW+ + ++GL N++ L+ GQ IEV P
Sbjct: 671 IPDFESDFVKLAARIEPQYAPKIAKQNSQFWLSQAKIGLSGIENVQNLL-GQSIEVQP-- 727
Query: 611 KNAGPQKSFVALDQPPEAVHQEAGLSLTLSAARRGSLKEGVPVTYREVTVGKVTGYELGQ 670
G +S + EA H AG + TL + +RGS+ G P+ YR++ VGKV LG+
Sbjct: 728 ---GNGESRFEFELHKEARHGGAGNTYTLQSEKRGSVSVGTPILYRDIEVGKVIDVRLGE 784
Query: 671 TADRVLIHILIEPKYAPLVRSGSRFWNTSGFGLDFGLFKGATVRTESLETLVAGGIAFAT 730
ADRV+ I I P+Y L+R S FWN SG + G+ GA V+ + ++++ GGI FAT
Sbjct: 785 FADRVITTIRIAPQYTYLLRQNSVFWNVSGLDMSIGI-TGANVKAGTFDSMLRGGITFAT 843
Query: 731 PDGERMGNPARPQ-QTFALFDKFEDEWLTWAPKIP 764
P+ +++ PA P+ TF L+ + ++EW W IP
Sbjct: 844 PEQKQL-TPAAPEGHTFYLYPQAQEEWTKWRTPIP 877
Score = 251 bits (641), Expect = 1e-70
Identities = 151/454 (33%), Positives = 255/454 (56%), Gaps = 10/454 (2%)
Query: 279 AGIRVKVKLTDFEGLQAGRTPVMYKGIQVGSLKTLKVDPDLSSANAELTLDPLAEDYLVQ 338
AG+R+++ + +GL AGRT + Y+G++VG ++ +K+ L S E + P A L
Sbjct: 46 AGVRIQIHFENAQGLIAGRTTIRYQGLEVGMVRDIKLSEGLDSIYVEADIYPEATKLLSN 105
Query: 339 DTQFWVVKPSISLAGITGLEALVKGNYIAIRPGDKGTAP-QREFVARAKAPPLDLRSPGL 397
T+FW+VKP+ SL+G++GL+ALV GNYIAI+PG ++ A AP L GL
Sbjct: 106 QTRFWMVKPTASLSGVSGLDALVSGNYIAIQPGSTHQEDYPTQYQALDSAPSDLLAQRGL 165
Query: 398 HMVLFTDNLGSLDVGSPILYKQVKVGSVQSYQFSRKNKQLVIGVHIEKEYENLVNGSTRF 457
+ L +LG + VGS I+YK++ +G V SYQ + ++I I++EY++++N +RF
Sbjct: 166 TISLKARDLGGISVGSQIVYKKIPIGEVFSYQLDDDAQSVIIQASIKEEYQHIINTESRF 225
Query: 458 WNASGVTLTGGLTGGIQVKSESLASLMAGGIAFETPEPNVPLKKRIPRFRLFADREAANQ 517
WN SG+ + G G+ V+ ESL++L+ G IA ++P+ P+++ +FRL+ D + A +
Sbjct: 226 WNVSGIGASIGFE-GVDVRLESLSALIGGSIAVDSPDEGKPVEQN-AQFRLYRDLKTAGR 283
Query: 518 HGTLVTIKV-DRADGMRPGTPVRFKGLDVGKIESVDLSADMQSVLLSARITQVADRIARA 576
G V+I + D + G P+ ++G+++G+I + L+ + +S++ SA I +
Sbjct: 284 -GIAVSITLPDDNNISASGAPIMYRGIEIGQITDLQLTENRKSIVASAAIQPAFSDMLNQ 342
Query: 577 GSQFWVVKPELGLMKTSNLETLVTGQYIEVLPAAKNAGPQKSFVALDQPPEAVHQEAGLS 636
GSQF + + ++ L NL LV G Y+ ++P A ++F A+ + + +S
Sbjct: 343 GSQFVLEEAQVSLTGVENLTNLVKGNYLTLIPGAGER--TRNFQAVRKNEFKYARSNSIS 400
Query: 637 LTLSAARRGSLKEGVPVTYREVTVGKVTGYELGQTADRVLIHILIEPKYAPLVRSGSRFW 696
L A L+ G P+ YR V VG VT L D V ++LI+ +Y L+RS +RF+
Sbjct: 401 FNLVADNSFGLEAGTPILYRGVAVGSVTAVNL--KLDYVEFNVLIDEQYGALIRSQNRFY 458
Query: 697 NTSGFGLDFGLFKGATVRTESLETLVAGGIAFAT 730
T + G +V + L+ G I+FA+
Sbjct: 459 VTGSAAAEL-TESGLSVSIPPAKQLLLGSISFAS 491
Score = 115 bits (287), Expect = 1e-29
Identities = 74/244 (30%), Positives = 127/244 (52%), Gaps = 12/244 (4%)
Query: 34 WRAYS------QQGIDIQVRFESGEGIQVNKTEVVYKGMPVGKVKALALDDEGNNRGVIA 87
W+ YS + G I + G++V T V Y+G+ +G+V + D E + + A
Sbjct: 625 WKLYSDYDHARRYGEKITLTALGTLGVKVG-TPVQYQGVQIGEVFEIIPDFESDFVKLAA 683
Query: 88 TIEMNKDVDQYLKTNTRFWLVKPSVSLAGITGLETLVSGNYIAASPGDGEPTRKFKALSE 147
IE + K N++FWL + + L+GI ++ L+ G I PG+GE +F+ E
Sbjct: 684 RIEPQY-APKIAKQNSQFWLSQAKIGLSGIENVQNLL-GQSIEVQPGNGESRFEFELHKE 741
Query: 148 EPPLSDAKPGLHLTVKADRLGSLNRGSPVFYKQIQVGQVKSYLLSEDQSTVEIKVYIEPT 207
G T+++++ GS++ G+P+ Y+ I+VG+V L E V + I P
Sbjct: 742 A---RHGGAGNTYTLQSEKRGSVSVGTPILYRDIEVGKVIDVRLGEFADRVITTIRIAPQ 798
Query: 208 YASLVRKHTRFWNASGISIDANLSGVKVRSESLSSIVAGGIAFATPENRKDSPPTDPSLP 267
Y L+R+++ FWN SG+ + ++G V++ + S++ GGI FATPE ++ +P
Sbjct: 799 YTYLLRQNSVFWNVSGLDMSIGITGANVKAGTFDSMLRGGITFATPEQKQLTPAAPEGHT 858
Query: 268 FRLY 271
F LY
Sbjct: 859 FYLY 862