Pairwise Alignments

Query, 701 a.a., (p)ppGpp synthetase from Pseudomonas simiae WCS417

Subject, 705 a.a., bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase from Vibrio cholerae E7946 ATCC 55056

 Score =  759 bits (1959), Expect = 0.0
 Identities = 365/702 (51%), Positives = 508/702 (72%), Gaps = 8/702 (1%)

Query: 5   DALADRLSAYLGPDQVNLVRRAYFYAEQAHDGQRRRSGEAYVTHPLAVANILADMHMDHQ 64
           D+L D    YL   Q+  +R++Y  A  AH+GQ R SGE Y+ HP+AVA ILA+M +D +
Sbjct: 5   DSLKDVAQEYLTEPQIEALRQSYVVARDAHEGQTRSSGEPYIIHPVAVARILAEMRLDLE 64

Query: 65  SLMAAMLHDVIEDTGIAKEALSAQFGETVAELVDGVSKLTQMNFETKAEAQAENFQKMAM 124
           +L AA+LHDVIED  + KE L A FG +VAELVDGVSKL ++ F  + EAQAENF+KM +
Sbjct: 65  TLQAALLHDVIEDCDVTKEDLDAHFGSSVAELVDGVSKLDKLKFRDRKEAQAENFRKMVL 124

Query: 125 AMARDIRVILVKLADRLHNMRTLEVLSGEKRRRIAKETLEIYAPIANRLGMHAIRIEFED 184
           AM +DIRVIL+KLADR HNMRTL  L  +K+RRIA+ETLEIYAP+A+RLG+H I+ E E+
Sbjct: 125 AMVQDIRVILIKLADRTHNMRTLGALRPDKKRRIARETLEIYAPLAHRLGIHNIKTELEE 184

Query: 185 LGFKAMHPMRSARIYQAVKRARGNRKEIVNKIEESLSHCLAIDEIEGEVSGRQKHIYGIY 244
           LGF+A++P R   + + VK ARGNRKE++ +I   +   L    +   V GR+K+++ IY
Sbjct: 185 LGFEALYPNRYRVLKEVVKAARGNRKEMIQRIHSEIEGRLQEVGLPARVVGREKNLFSIY 244

Query: 245 KKMRGKRRAFNEIMDVYAFRIIVDKVDTCYRVLGAVHNLYKPLPGRFKDYIAIPKANGYQ 304
            KM+ K + F+ IMD+YAFRI+VD  DTCYRVLG VH+LYKP P R KDYIA+PKANGYQ
Sbjct: 245 NKMKTKEQRFHTIMDIYAFRIVVDTADTCYRVLGQVHSLYKPRPARMKDYIAVPKANGYQ 304

Query: 305 SLHTTLFGMHGVPIEIQIRTREMEEMANNGIAAHWLYKSSGDEQPKGTHARARQWVKGVL 364
           SLHT++ G HGVP+E+QIRT +M++MA+ G+AAHW YK++ +        +A++W++ +L
Sbjct: 305 SLHTSMVGPHGVPVEVQIRTEDMDQMADKGVAAHWSYKANSERGGTTAQIKAQRWMQSLL 364

Query: 365 EMQQRAGNSLEFIESVKIDLFPDEVYVFTPKGRIMELPKGSTAVDFAYAVHTDVGNSCIA 424
           E+QQ AGNS EFIE+VK DLFPDE+YVFTPKGRI+ELP G+TAVDFAYAVHTD+GN+C+ 
Sbjct: 365 ELQQSAGNSFEFIENVKSDLFPDEIYVFTPKGRIVELPMGATAVDFAYAVHTDIGNTCVG 424

Query: 425 CRINRRLAPLSEPLQSGSTVEIVSAPGARPNPAWLNFVVTGKARTHIRHALKLQRRSESI 484
            R++R   PLS+ L+SG TVEI+SAPGARPN AWLN+VVT +ART IR  LK  RR +SI
Sbjct: 425 ARVDRTPYPLSQSLKSGQTVEIISAPGARPNAAWLNYVVTSRARTKIRQVLKTMRREDSI 484

Query: 485 SLGERLLNKVLNGFDSALDKIPTERVQAMLHEYRQETIEDLLEDIGLGNRMAYVVARRLL 544
           +LG RLLN  L   + ++++I  E +  +L + +  +++DLL  IGLG  M+ V+ARRLL
Sbjct: 485 TLGRRLLNHALG--EHSVNEIAPENISKVLSDLKIASMDDLLAAIGLGELMSIVIARRLL 542

Query: 545 GEGEQLPSP------EGPLAIRGTEGLVLSYAKCCTPIPGDPIVGHLSAGKGMVVHLDNC 598
           G  ++L  P      +  L IRG EG++L++A CC PIP D I+ H+S G+G+VVH + C
Sbjct: 543 GNADELTEPSKSGGNKNKLPIRGAEGILLTFANCCHPIPDDHIIAHVSPGRGLVVHRETC 602

Query: 599 RNITEIRHNPEKCIQLSWAKDVTGEFNVELRVELEHQRGLIALLASSVNAADGNIEKISM 658
            N+   +  P+K + + W KD   EF  EL+V++ +++G +A L + ++    NI  +S 
Sbjct: 603 PNVRGYQKEPDKYMAVEWTKDYDQEFITELKVDMHNRQGALAELTNVISKTGSNIHGLST 662

Query: 659 DERDGRISVVQLVVSVHDRVHLARVIKKLRALTGVIRITRMR 700
           +ERDGR+  V ++++  DRVHLA +++K+R +   +++ R +
Sbjct: 663 EERDGRLYTVTVLLTTKDRVHLAGIMRKIRTMPHALKVRRRK 704