Pairwise Alignments

Query, 701 a.a., (p)ppGpp synthetase from Pseudomonas simiae WCS417

Subject, 738 a.a., GTP diphosphokinase from Vibrio cholerae E7946 ATCC 55056

 Score =  386 bits (992), Expect = e-111
 Identities = 227/681 (33%), Positives = 365/681 (53%), Gaps = 43/681 (6%)

Query: 55  ILADMHMDHQSLMAAMLHDVIEDTGIAKEALSAQFGETVAELVDGVSKLT---QMNFE-- 109
           IL  + MD  +L+AA+L  +     +  E+L   +G  V +L+ GV ++    Q+N    
Sbjct: 64  ILITLSMDRPTLVAALLFPIATSGVLDNESLEEGYGREVVKLIHGVEEMAAIGQLNVTMH 123

Query: 110 -TKAEAQAENFQKMAMAMARDIRVILVKLADRLHNMRTLEVLSGEKRRRIAKETLEIYAP 168
            ++A AQ +N ++M +AM  D R +++KLA+R+ N+R ++    E RR  AKE   IYAP
Sbjct: 124 GSEASAQVDNVRRMLLAMVDDFRCVVIKLAERICNLREVKNEPDEVRRVAAKECANIYAP 183

Query: 169 IANRLGMHAIRIEFEDLGFKAMHPMRSARIYQAVKRARGNRKEIVNKIEESLSHCLAIDE 228
           +ANRLG+  ++ E ED  F+   P    +I + +   R  R++ +      L   +    
Sbjct: 184 LANRLGIGQLKWEIEDYAFRYQQPDTYKQIAKQLSERRIVREQYIRDFVSDLRAEMKQSG 243

Query: 229 IEGEVSGRQKHIYGIYKKMRGKRRAFNEIMDVYAFRIIVDKVDTCYRVLGAVHNLYKPLP 288
           I  EVSGR KHIY I++KM+ K  AF+E+ DV A RII DK+  CY  LG VH  YK LP
Sbjct: 244 INAEVSGRPKHIYSIWRKMQKKSLAFDELFDVRAVRIIADKLQDCYAALGIVHTKYKHLP 303

Query: 289 GRFKDYIAIPKANGYQSLHTTLFGMHGVPIEIQIRTREMEEMANNGIAAHWLYKSSGDEQ 348
             F DY+A PK NGYQS+HT + G  G  IEIQIRT++M E +  G+AAHW YK  G   
Sbjct: 304 NEFDDYVANPKPNGYQSIHTVILGPEGKTIEIQIRTKQMHEESELGVAAHWKYK-EGSSA 362

Query: 349 PKGTHARARQWVKGVLEMQQRAGNSLEFIESVKIDLFPDEVYVFTPKGRIMELPKGSTAV 408
            +  +     W++ +L+ Q+   +S E ++ ++  +F D VY FTPKG +++LP G+T +
Sbjct: 363 ARSGYDEKITWLRKLLDWQEEMSDSGEMLDELRSQVFDDRVYAFTPKGDVVDLPMGATPL 422

Query: 409 DFAYAVHTDVGNSCIACRINRRLAPLSEPLQSGSTVEIVSAPGARPNPAWLN----FVVT 464
           DFAY +H++VG+ CI  ++  R+ P +  LQ G  VEI++A    P+  WLN    FV +
Sbjct: 423 DFAYHIHSEVGHRCIGAKVAGRIVPFTHKLQMGDQVEIITAKEPNPSRDWLNPSLGFVHS 482

Query: 465 GKARTHIRHALKLQRRSESISLGERLLNKVLNGFDSALDKIPTERVQAMLHEYRQETIED 524
           G+AR  I    + Q R +++  G  +L   L    + L           L  +   ++++
Sbjct: 483 GRARAKINAWFRKQSREKNLEAGREILEIELAKIGANLKHAEA----YALKRFNVNSVDE 538

Query: 525 LLEDIGLG--------NRMAYVVARRLLGEGEQLP----------SPEGP----LAIRGT 562
           +   IG G        N +  +V +    E ++L           +P  P    + + G 
Sbjct: 539 MYVGIGSGDLRINQIVNHINALVNKPTAEEEDKLALEKLQENKTLTPNRPHKDAVVVEGV 598

Query: 563 EGLVLSYAKCCTPIPGDPIVGHLSAGKGMVVHLDNCRNITEIR-HNPEKCIQLSWAKDVT 621
           + L+   A+CC PIPGD I G+++ G+G+ VH  +C  + E+  H PE+ I   W     
Sbjct: 599 DNLMTHLARCCQPIPGDEIRGYITQGRGISVHRSDCEQLEELSLHAPERIIDTVWGSGFV 658

Query: 622 GEFNVELRVELEHQRGLIALLASSVNAADGNIEKISMDERDG---RISVVQLVVSVHDRV 678
           G + + +RVE   + GL+  + + +  A+  ++  SM  R     +I ++   + V++  
Sbjct: 659 GSYLLTVRVEAMERSGLLKDITTLL--ANEKVKVASMKSRSDYKRQIIIMDFDLEVNNVE 716

Query: 679 HLARVIKKLRALTGVIRITRM 699
            LARV K++  +  V+ + R+
Sbjct: 717 ALARVSKRIEQIKDVMLVKRL 737