Pairwise Alignments

Query, 946 a.a., adenylate cyclase from Pseudomonas simiae WCS417

Subject, 843 a.a., class I adenylate cyclase from Vibrio cholerae E7946 ATCC 55056

 Score =  407 bits (1045), Expect = e-117
 Identities = 274/828 (33%), Positives = 408/828 (49%), Gaps = 38/828 (4%)

Query: 26  RFMALNEGRMARAIEGLTPRQQSVLNLLPLFFHVNHPLLPGYVSGSTPAGLSNYE--PDA 83
           R   LN  R+ RA+  +  + Q V +L+P  F  NHPL+PGY S  TP G+  +E  P  
Sbjct: 11  RLDKLNRQRIERALALMDLQSQRVFHLIPALFQFNHPLIPGYFSADTPFGIHLFEANPIQ 70

Query: 84  QALTEAQRLTRSFSYKPRHGNPPRPILGLFLMGSLGTLAQADQSDMDVWVCHAADLSETE 143
           Q   +  +LT      P   NP   ILGL+ MGS  ++ Q+  SD+D+WVC +A +S   
Sbjct: 71  QQFIDDAQLTLGEPLTPAD-NPA--ILGLYTMGSTSSIGQSTSSDLDIWVCVSAQMSCEA 127

Query: 144 LAELRKKCQLLEAWALTMGAEAHFFLIEPTRFVLGERDTQLSSDDCGTTQHYLLLDEFYR 203
              L  KC L+  WA + G EA+FF++   RF     +  LS ++CG++QH LLLDEFYR
Sbjct: 128 RDNLSSKCLLITDWAKSQGVEANFFIMNEERFRHNHSEA-LSGENCGSSQHLLLLDEFYR 186

Query: 204 TAIWLAGRTPIWWLVPVYEETRYAEFTHTLISKRFIRADETLDLGHLARIPPGEFIGAGL 263
           +A+ LAG+  +W +VP   E  Y E+ H L S  ++  +E +D G L RIP  E+ GA L
Sbjct: 187 SAVRLAGKRLLWQIVPPEMEECYDEYVHELCSNGYLNCNEWIDFGKLNRIPAEEYFGANL 246

Query: 264 WQLFKGIESPYKSVLKLLLTEVYASEHPNVHCLSLRFKRAVFANQMDLDELDPYIVVYRR 323
           WQL+K I+SPYKSVLK +L E Y+ E+P+   LS+  KR  FA++ DL  +D Y  +  +
Sbjct: 247 WQLYKSIDSPYKSVLKAILLEAYSWEYPHTQLLSIDSKRRFFADEPDLYGMDSYYQMLEK 306

Query: 324 IEEYLKARNEPERLELVRRALYLKVNRKLSASQRTTS--WQRLLLERLAHEWGWDQRQLA 381
           +  YL    +  RL+LVRR  YLK + KLS      S  W+R  L  L  EW W    +A
Sbjct: 307 VTRYLVRIGDSTRLDLVRRCFYLKTHEKLSREPGVGSMPWRREALRELTSEWQWSADLIA 366

Query: 382 LLDSRSQWKVRQVASERRALVSELNYSYRFLTQFARTEQTVSLINKRDLNVLGRRLYAAF 441
            LD+R  WKV QV     AL+  L  SYR L QFAR     S I+ +D+++L R+LYAAF
Sbjct: 367 ELDNRRHWKVEQVKVVHHALLDALMLSYRNLIQFARRNDITSAISPQDISILARKLYAAF 426

Query: 442 ERKAGKVEFINPGIAPDLAEDTLTLVQ--SPNRKEPGQHHWGLYNGNLTALEWEHFAPIK 499
           E   GKV  +NP I+PDL E  L+ ++  +    +PG   W LY   L A        ++
Sbjct: 427 EVLPGKVTLLNPQISPDLHEPDLSFIEVCAGRTNKPG---WYLYKQPLQAQRLIGQPYLE 483

Query: 500 RSRDLLEMLTWCHRNGVIDSSTRLALHPGTSDMTEFELFNLLGSLQQTIDLPLTSVDEQR 559
            +  L +++ W   NG+I  STRL      + +   + + ++  L+ T  L       Q 
Sbjct: 484 HNEYLSKLVAWAFFNGLITESTRLHAVVREAQLDIDKFYQMVSDLRNTFSLRKRRPTMQA 543

Query: 560 LLRSAVPEEVLLLINVGVDPLKHHRDLNILMTTERTDSLSYAGVRDNLVLTLDQVTLNSW 619
           L       ++ + IN   DP        + +  +  D  S+   +  LV ++D V  NSW
Sbjct: 544 LANPCEISQLAMFINFEHDPTSELSGKALKVDLKNIDIFSFGAEQKCLVGSVDLVYRNSW 603

Query: 620 NEVMVSRYDGPHALLDCLRDYLNQLPPDHLPRLRVRCFCHNR------AQFIARRVEEIF 673
            EV    ++G  A+LD L+  L ++  D LP   V  FC+++         + + + E  
Sbjct: 604 QEVRTLHFEGQTAMLDALKTVLGKMHQDALPPESVDVFCYSKNLRGVMRNLVYQLLAECI 663

Query: 674 DTAQNLLLSQGNHRY--VLQVQQHYHVMELMPGQANHVSLATQDALVAYLSEELASYSPL 731
           D     +  +   R+  +    Q Y +     G +      + D   +  + +L     L
Sbjct: 664 DLRLKPMEQEKRRRFKALRMGDQMYGLFFERRGVSVQKLENSVDFYRSISTNKLKGSPLL 723

Query: 732 HLDAMALEDHDL-AVLLPMGMADCVQVFYRVNEGFAELYVLDEFNALWQQRLPFHDEQSL 790
            LD    +D+ L AV+        VQ F+   E    +YVLDE N +        ++  +
Sbjct: 724 MLDRD--QDYPLPAVVDSFASEGLVQFFFEDTEKGFNIYVLDEANRVEVYHQFNGEKDEM 781

Query: 791 LAPLQRFLQSIIYRRDALSPLDPQEPLGAVQV-----LYYQLLPSVSG 833
           +A +  F  S+         LD    LGA  +      YYQ++    G
Sbjct: 782 IASVNSFYTSM---------LDDSNKLGAKSINFNLPQYYQIIHPEEG 820