Pairwise Alignments

Query, 435 a.a., folylpolyglutamate synthase from Pseudomonas simiae WCS417

Subject, 421 a.a., bifunctional tetrahydrofolate synthase/dihydrofolate synthase from Vibrio cholerae E7946 ATCC 55056

 Score =  331 bits (849), Expect = 2e-95
 Identities = 192/421 (45%), Positives = 253/421 (60%), Gaps = 16/421 (3%)

Query: 6   LGEWLAYLEQLHPSAIDMGLERSQQVAARLGLGRPAPRVITVTGTNGKGSTCAFVAALLQ 65
           L  WL YL  +H SAID+GLER Q VA +  L +PAP VITV GTNGKGSTCA + A+L 
Sbjct: 13  LAVWLDYLAHIHTSAIDLGLERVQAVAQKAKLTKPAPTVITVAGTNGKGSTCALMEAILL 72

Query: 66  AQGLKVGVYNSPHLLRYNERVQLNGVEATDEQLCEAFAALDAGRGEISLTYFEMGTLAAF 125
             G  VGVY+SPHL+RYNERV++NG +  DE   +AFA ++  RG+ISL+ FE GTLAA 
Sbjct: 73  QAGYSVGVYSSPHLIRYNERVRINGQDLADEMHTQAFAHIEQERGDISLSLFEFGTLAAL 132

Query: 126 WLFERAQLDVVVLEVGLGGRLDTVNVVDADLALVTSIGVDHADYLGNTRESVAYEKAGIF 185
           +LFE+ ++DV++LEVGLGGRLD  NVVD D++++TS+ +DH D+LGN    + YEKAGIF
Sbjct: 133 YLFEQQKVDVLLLEVGLGGRLDATNVVDHDVSVITSLALDHTDWLGNDIAVIGYEKAGIF 192

Query: 186 RQGKPALCGDLDPPHTLLDKVRELDCPFFLRGRDFNLE-IGAQHWQWR-GRDARGQVVEL 243
           R GKPA+CG   PP T+     ++          F+ E   A  W WR GR       EL
Sbjct: 193 RSGKPAICGQPKPPATVAAHADDIGAKLHQVEIQFSYEKTSATTWNWRSGR------FEL 246

Query: 244 CDLPLLNLPMENAALALQAYLLLDLPWNAEQIAATLLSTRVVGRLDRREFQWQGKRLNLL 303
            DLP+ +LP+ NAA AL A     L  +   I   L + ++ GR+     Q    +  ++
Sbjct: 247 TDLPIPSLPLPNAATALMALGCSGLAISDINIVDGLRNAQLAGRM-----QVISHQPTIV 301

Query: 304 LDVGHNPHAAEYLAQRLSRTPPVGRRLAVFGLLADKDLDGVVAPLLGSVQAWAVAPLDTS 363
           LDV HNPH+A YL Q+L++  P      VFG+L DKD+   V  L  +V  W  A L   
Sbjct: 302 LDVAHNPHSAHYLVQQLTQRYPERTIHLVFGMLHDKDIASTVVELSPAVTHWYPASLSGP 361

Query: 364 RSRPAAELEVALQNLGAPVASYASVTDALEAQCAVATPDDEILLFGSFYCVAEALEWLAR 423
           R+  AA+L    Q L A +  YA+   A EA    A   D I++ GSF+ V E LE   +
Sbjct: 362 RAATAAQL---CQYLPADITQYANPVSAFEAALTQAGAQDVIVVAGSFHTVGEVLEHWQK 418

Query: 424 R 424
           R
Sbjct: 419 R 419