Pairwise Alignments
Query, 3949 a.a., peptide synthase from Pseudomonas simiae WCS417
Subject, 6676 a.a., Amino acid adenylation from Pseudomonas syringae pv. syringae B728a
Score = 1592 bits (4122), Expect = 0.0
Identities = 1051/2671 (39%), Positives = 1473/2671 (55%), Gaps = 129/2671 (4%)
Query: 50 LPLSYAQERQWFLWQLDPDS-ATYHIPGALRLQGRLDLAALQRAFDSLLARHESLRTRLV 108
LPLS+AQ+R WFL QLD + A YHIP LRL+GRLD ALQ D ++ARHE+LRT
Sbjct: 3204 LPLSWAQQRLWFLDQLDRAAGAAYHIPAGLRLRGRLDSDALQATLDRIVARHEALRTHFA 3263
Query: 109 QDGERLLQNVAPE------ARIEIRQ-DVADEQQLLARVEAEIA-RPFDLQAGPLLRVSL 160
+ +Q +APE A ++R D A + + + R+ E A PFDL +GPL+R L
Sbjct: 3264 LHEGQAIQVIAPETQGFALASHDLRALDSAAQHEAVERLAREEALAPFDLSSGPLIRGRL 3323
Query: 161 LQLAEDEHVLVMVQHHIISDGWSMQVMVEELVQFYAAHSQGREVQLPGLPIHYADYALWQ 220
+QL++ EH+L++ QHHI+SDGWS V++ E+ Y A SQG LP L Y DYA WQ
Sbjct: 3324 VQLSQTEHILLVTQHHIVSDGWSTGVLLHEIGTLYRAFSQGLADPLPALAFQYVDYAAWQ 3383
Query: 221 RSWMEAGEKARQLAYWQDLLGGEQPVLELPLDHPRPAQQSHCGASLQVHLPADLVAGIKR 280
R W++ Q+ +W+ L G +LELP DH RP +S+ G + + L L AG+++
Sbjct: 3384 RQWLQGETLHTQVEFWRQHLSGAPALLELPTDHRRPPLRSYAGGRVSLALSPALTAGLRQ 3443
Query: 281 LAQQEGVTPFMLLLASFQTLLFRYSGQSDIRIGVPNANRNRVETERLIGFFVNTQVLKAD 340
L Q+ G T FM LL + +LL R+SGQ D+ IG P ANR R E E LIGFFVNT L+
Sbjct: 3444 LGQRHGATLFMTLLVGWSSLLSRFSGQDDVVIGTPVANRPRSELESLIGFFVNTLALRIR 3503
Query: 341 LDGQMSFAELLQQAKRRSLEAQAHQDLPFEQLVVALQPERSLSHNPLFQVMFNHQTDAQG 400
G +S A LL+Q K L A AHQDLPFEQ+V ALQP RSL H+P+FQVM G
Sbjct: 3504 PQGGLSVAALLEQVKAVMLAAHAHQDLPFEQVVEALQPPRSLGHSPIFQVMLALNNTPGG 3563
Query: 401 GRDGQQLPGLRVAQLDWENQTTHFDLSLDTHESAEGLWAALTYATDLFESATIERLAQHW 460
G LP L + L + T FDLSL E+ GL +L YA+DLFE ATIER+A H
Sbjct: 3564 GE--LSLPELSLEPLQAPHTTAQFDLSLALVEADGGLIGSLEYASDLFERATIERIAGHL 3621
Query: 461 QNLLQAAVSAPRSRLCVLSMLDAPEQQRMLKDWN-APATVAAPHAVHQLFEAQAREHPAR 519
Q LL+ V+ + + L +L +++++L+ +N A A +HQLFE QA + P
Sbjct: 3622 QVLLEGMVADDQQAVAELPLLSCEQRRQVLESFNDTAAAYPAEKLLHQLFEEQAAQQPDA 3681
Query: 520 QALALDDQTLSYGELNRQANRLAHYLIAQGVGPEVLVGIAVERSFAMVVSLLAVLKAGGA 579
A+ + +L+YGELN +ANRLAHYLI G+ P+ V I +RS MVV LL +LKAGGA
Sbjct: 3682 LAVVDETASLTYGELNARANRLAHYLIGLGIQPDDRVAICAQRSLEMVVGLLGILKAGGA 3741
Query: 580 YVPLDPEYPRERLVHMLDDSGVRLVLTQSHLRDRLP-LPADLTALDIDLADAQLAQCAEH 638
YVPLDP YP ERL +ML+DS VL Q L++ LP + LD + +
Sbjct: 3742 YVPLDPGYPPERLRYMLEDSAPVAVLVQEALQECLPAVNVPQVVLDSVVLSSGTGGLPCG 3801
Query: 639 NPPT---AFEPRSLAYVIYTSGSTGKPKGVAISHAALSEFAGIAAEYSRLVADDRVLQFA 695
NP R AYV+YTSGS+G PKGV I H ++ I Y+R+ +D V A
Sbjct: 3802 NPDLDALGLTSRMPAYVMYTSGSSGVPKGVLIEHRSVLRLV-INNPYARITTEDCVAHGA 3860
Query: 696 TLNFDGFVEQLYPALTLGATV-VLRGPQLWDGADLYRQIIDQGITLADLPTAYWKLFLQD 754
FD +++ AL GA + V+ L + A L +I+ G+T L + ++ D
Sbjct: 3861 NTAFDASTWEIWSALLNGAKLLVVSQATLLNPARLNHVLIEGGVTALWLTAGLFNEYV-D 3919
Query: 755 CLAAGPRPYGALRQVHIGGEAM-PLDGPVLWRRAGLGHVRLLNTYGPTEATVVSSVLDCS 813
LA + LR + +GG+ + P+ + RA L+N YGPTE T +S +
Sbjct: 3920 VLAVA---FSKLRYLLVGGDVLDPVSVAKVLSRAHRPR-HLINGYGPTETTTFASTYEIH 3975
Query: 814 --DDNAVMGATASPIGRALPGRGLYVLDPDLNLLPVGAVGELYIASAGGLARDYLQRPSL 871
DN+ + PIGR + +Y+LD +P+G GE++I AG +AR YL P L
Sbjct: 3976 ALSDNS----RSIPIGRPIGNTRIYLLDAHGQPVPIGVSGEIHIGGAG-VARGYLNLPEL 4030
Query: 872 TAERFVADPFSTL-GERLYRTGDLARYRADGVIEYVGRVDHQVKIRGFRIELGEIEALLL 930
TAERF+ DPFS R+YR+GDL R+ ADG IEY+GR D QVK+RGFRIELGEIE+ L
Sbjct: 4031 TAERFLDDPFSAEPAARMYRSGDLGRWLADGNIEYLGRNDDQVKLRGFRIELGEIESQLA 4090
Query: 931 AQEAVREAFLLA-----ADNQLVAYLVPAQP--LSAAEQAAAGETLKATLREQLPDYMVP 983
A VREA +L D +LVAYL + LSAA+ L+ L + L +YM+P
Sbjct: 4091 ACPGVREAVVLVREHRPGDKRLVAYLTAQEGALLSAAQ-------LREQLSQGLAEYMIP 4143
Query: 984 AHLIFLDRMPLNPNGKLDRQALPKPDGSA-VQQAWQAPVTPRQQQVAAIWADILGVERVG 1042
+ + L R PL PNGKLDR+ALP P+ A + ++AP + +A IW +LG+ERVG
Sbjct: 4144 SAFVTLARFPLTPNGKLDRRALPAPEDDAYASRGYEAPAGEIEHALAEIWQALLGLERVG 4203
Query: 1043 LTHHFFELGGHSLLAMQVVSRIRQALKLEVPLKLLFEQPRLEGFVAALATQDPDAPTA-P 1101
HFFELGGHSLLA+Q+VSR+RQ ++EV L+ +F +P L+G +A A T
Sbjct: 4204 RHDHFFELGGHSLLAVQLVSRLRQRFEVEVALRDVFAEPTLQGLARQVANARLSAQTPLT 4263
Query: 1102 ALLPVGRDQPLPLSYAQERQWFLWQLEPQS-AAYHIPSALRLKGQLDLGALQRSFDTLLA 1160
+L PV RD PLPLS+AQ+R WFL QL+ + AAYHIP+ LRL+G+LD ALQ + + ++A
Sbjct: 4264 SLTPVDRDLPLPLSWAQQRLWFLDQLDRAAGAAYHIPAGLRLRGRLDSEALQATLERIVA 4323
Query: 1161 RHESLRTHLRQERDRTVQIISPQVS---------LQIAHAEVHEAQLKARVEAEIAQPFN 1211
RHE+LRTH + +Q+I+P+ + A HEA + E +A PF+
Sbjct: 4324 RHEALRTHFALHEGQAIQVIAPETQGFALASHDLRALDSAAQHEAVERLAGEEALA-PFD 4382
Query: 1212 LEQGPLLRVSLLRIAADEHVLVLVQHHIVSDGWSMQLMVEELVQLYAAYSQGQVLQWPAL 1271
L GPL+R L++++ EH+L++ QHHIVSDGWS +++ E+ LY A+SQG PAL
Sbjct: 4383 LSSGPLIRGRLVQLSQTEHILLVTQHHIVSDGWSTGVLLHEIGMLYRAFSQGLADPLPAL 4442
Query: 1272 PIQYADYAVWQRNWMEAGEKARQLAYWRDMLGGEQSVLALPFDHPRPAVQSHRGARLAFE 1331
QY DYA WQR W++ Q+ +WR L G ++L LP DH RP ++S+ G R++
Sbjct: 4443 AFQYVDYAAWQRQWLQGETLQTQVDFWRQHLSGAPALLELPTDHRRPPLRSYAGGRVSLA 4502
Query: 1332 LPGALTQGLKALAKQQDVTLFMLLLASFQTLLHRYSGQEEIRVGVPIANRNRSETERLIG 1391
L ALT GL+ L ++ TLFM LL + +LL R+SGQ+++ +G P+ANR RSE E LIG
Sbjct: 4503 LSPALTAGLRQLGQRHGATLFMTLLVGWSSLLSRFSGQDDVVIGTPVANRPRSELESLIG 4562
Query: 1392 FFVNTQVLKADLHGQMSVEQLLQQARQRALDAQAHQDLPFEQLVEALQPERSLSHNPLFQ 1451
FFVNT L+ G +SV LL+Q + L A AHQDLPFEQ+VEALQP RSL+H+P+FQ
Sbjct: 4563 FFVNTLALRIRPEGHLSVAALLEQVKAVMLAAHAHQDLPFEQVVEALQPPRSLAHSPIFQ 4622
Query: 1452 VMFNHQTDVGQAQVQQQLPNLSVEGLEWESKTAHFDLDLDIQESTEGIWATLGYAQDLFE 1511
VM G ++ LP LS+E L+ TA FDL L + E+ G+ +L YA DLFE
Sbjct: 4623 VMLALNNTPGGGEL--SLPELSLEPLQAPHTTAQFDLSLALVEADGGLIGSLEYASDLFE 4680
Query: 1512 ASTVQRMARHWQNLLQGMVADPRQTLSQLNLLDNTERQQILQRWDQSDAGFSAKRLVHEL 1571
+T++RMA H Q LL+GMVAD +Q++++L LL +R+Q+L+ ++ + A + A +L+H+L
Sbjct: 4681 RATIERMAGHLQVLLEGMVADDQQSVAELPLLSCEQRRQVLESFNDTAAAYPADKLIHQL 4740
Query: 1572 VADRAGETPEAVAVKFGEQQLTYGELDRQANRLAHALIARGVGPEVRVAIAMPRSAEIMV 1631
++A + P+A+AV LTYGEL+ +ANRLAH LI G+ P+ RVAI RS E++V
Sbjct: 4741 FEEQAAQQPDALAVVDDAASLTYGELNARANRLAHYLIGLGIQPDDRVAICAQRSLEMVV 4800
Query: 1632 AFLAVMKAGGVYVPLDIEYPRDRLLYMMQDSRARLLLTHSTVQQRLPIPDGLEALAVD-Q 1690
L + KAGG YVPLD YP RL YM++DS +L + ++ L L +D Q
Sbjct: 4801 GLLGIFKAGGAYVPLDPAYPEQRLRYMLEDSAPVAVLVQTETRRLL---GELAVPTLDLQ 4857
Query: 1691 TQAWSANDDSAPEV-VLDGDNLAYVIYTSGSTGMPKGVAVSHGPLVAHIIATGERYETSP 1749
W + P V + +LAYVIYTSGSTG PKGV H +V + +
Sbjct: 4858 EGDWEVEPEHNPVVPAITPQHLAYVIYTSGSTGKPKGVGGPHQAMVNRLYWMHNTFGGQR 4917
Query: 1750 ADCELHFMSFAFDGSHEGWMHPLINGASV-LIRDDSLWLPEYTYQQMHRHHVTMAVFPPV 1808
+ S +F S + PL+ GA + ++ + P +Q + H +T V P
Sbjct: 4918 LEKHAQKTSISFLDSVTETLMPLLFGAQLHIVSPLASRDPLQLWQAVTEHQLTRLVLVPS 4977
Query: 1809 YLQQLAEHAERDGNPPKVRVYCFGGDAVAQASYDLAWRALKPT-YLFNGYGPTETVVTPL 1867
L++L+ R +P K + C G V +S RA P+ + N YG +E
Sbjct: 4978 LLEELSRIENRQVSPEKRLIVCSG--EVFSSSLLARTRAWLPSATILNFYGSSEAAGDST 5035
Query: 1868 LWKARKGDPCGAVYAPIGTLLGNRSGYVLDAQLNLQPIGVAGELYLGGEGVARGYLERPA 1927
+ G PIG + N Y+LDA PIGV+GE+++GG GVARGYL P
Sbjct: 5036 FYLCDSAVQAGH-SLPIGRPIANTRIYLLDAHGQPVPIGVSGEIHIGGAGVARGYLNMPE 5094
Query: 1928 LTAERFVPDPF-GKPGSRVYRSGDLTRGRPDGGVDYLGRVDHQVKIRGFRIELGEIEARL 1986
LTAERF+ DPF +P +R+YRSGDL DG ++YLGR D QVK+RGFRIELGEIE++L
Sbjct: 5095 LTAERFLDDPFSAEPTARMYRSGDLGCWLADGNIEYLGRNDDQVKLRGFRIELGEIESQL 5154
Query: 1987 REQDSVGETVVVAQE-GPSGKQLVAYVVPLDPLLIDDAVAQSTCREALRRALKARLPDYM 2045
V E VVVA+E P K+LVAY+ + ++ A LR L L +YM
Sbjct: 5155 AACPGVREAVVVAREHRPGDKRLVAYLTAQEGAVLSAA--------QLREQLSQGLAEYM 5206
Query: 2046 VPTHLMFLERMPLTPNGKLDRKGLPRP-DVSQMQQVYVAPQSELEQKIAAIWSDVLRLPR 2104
+P+ + L R PLTPNGKLDR+ LP P D + + Y AP E+E +A IW +L L R
Sbjct: 5207 IPSAFVTLARFPLTPNGKLDRRALPTPKDDAYASRGYEAPAGEIEHALAEIWQTLLGLER 5266
Query: 2105 VGLHDNFFELGGDSIISIQVVSRARQA-GVRFTPKDLFQHQTVQSLAAVAREGEGAVVLD 2163
VG HD+FFELGG S++++Q+VSR RQ V +D+F T+Q L AR+ A +
Sbjct: 5267 VGRHDHFFELGGHSLLAVQLVSRLRQRFEVEVALRDVFAEPTLQGL---ARQVANARLSA 5323
Query: 2164 QSALTGDLLLLPV------------QQAFFADDIPRR--HHWNQSVVLQPHQALQAPLLV 2209
Q+ LT L PV Q+ +F D + R ++ L+ L + L
Sbjct: 5324 QTPLTSLTPLTPVDRNLPLPLSWAQQRLWFLDQLDRAAGAAYHIPAGLRLRGRLDSDALQ 5383
Query: 2210 AALQALIVHHDALRIGFVQGAAGWSAAYRGPQQHQAEQVLWQTTLNAVEELEAL----GE 2265
A L + H+ALR F Q A L++ + EA+ GE
Sbjct: 5384 ATLDRTVARHEALRTHFALHEGQTIQVIAPDTQGFALASHDLRALDSAAQHEAVQQLAGE 5443
Query: 2266 EAQRSLDLSEGPLLRAVLVDLADGSQRLLLVIHHLVVDGVSWRILLEDLQTAYRQVAQGA 2325
EA DLS GPL+R LV L++ LL+ HH+V DG S +LL ++ T YR +QG
Sbjct: 5444 EALAPFDLSRGPLIRGRLVQLSETEHILLVTQHHIVSDGWSTGVLLHEIGTLYRAFSQGL 5503
Query: 2326 KVVLPAKTSAIRAWAERLQAYARSAALAQELAWWQTQLQGSPT--GLPGADPQASLSNRH 2383
LPA +A + + + L ++ +W+ L G+P LP + L +
Sbjct: 5504 ADPLPALAFQYVDYAAWQRQWLQGETLHTQVEFWRQHLSGAPALLELPTDHRRPLLRSYA 5563
Query: 2384 ALSVTTHLDQVFTRRLLQDAPSAYRTQINDLLLTALARVVVRWTGDASMLIRLEGHGRED 2443
V+ L T L Q + + LL + ++ R++G ++I R
Sbjct: 5564 GGRVSLALSPALTAGLRQ-LGQRHGATLFMTLLVGWSSLLSRFSGQDDVVIGTPVANR-- 5620
Query: 2444 LFDEIDLTRTVGWFTSLYPVKLVPTDSLAGSLKQIKEQLRAIPDKGLGFGALRYLGNAEA 2503
+L +G+F + +++ P L S+ + EQ++A+ L + EA
Sbjct: 5621 --PRSELESLIGFFVNTLALRIRPQGHL--SVAALLEQVKAVMLAAHAHQDLPFEQVVEA 5676
Query: 2504 QQALSELPRPRITFNYLGQFDGSFDGGEQEGLFVPSGDGSGAEQSGEAPLGNWLEINGQV 2563
Q L I F + + + GGE + + + L L
Sbjct: 5677 LQPPRSLGHSPI-FQVMLALNNTPGGGELSLPELSLEPLQAPHTTAQFDLSLALVEADGG 5735
Query: 2564 YAGELKLNWSFSQQMFDEATVQRLADDYAAELKALIEHCGVNQGVTPSDFPLARLSQAQL 2623
G L+ ++ +F+ AT++R+ A L+ L+E + + PL LS Q
Sbjct: 5736 LIGSLE----YASDLFERATIERM----AGHLQVLLEGMVADDQQAVGELPL--LSCEQR 5785
Query: 2624 DSLPVTVADIEDVYPLSPMQQGMLFQSLYGE 2654
+ + D YP G L L+ E
Sbjct: 5786 RQVLESFNDTAATYP-----AGTLLHQLFEE 5811
Score = 1531 bits (3965), Expect = 0.0
Identities = 945/2177 (43%), Positives = 1270/2177 (58%), Gaps = 104/2177 (4%)
Query: 36 AQLPIASIR--EDGQMLPLSYAQERQWFLWQLDPDS-ATYHIPGALRLQGRLDLAALQRA 92
AQ P+ S+ + LPLS+AQ+R WFL QLD + A YHIP LRL+GRLD ALQ
Sbjct: 4258 AQTPLTSLTPVDRDLPLPLSWAQQRLWFLDQLDRAAGAAYHIPAGLRLRGRLDSEALQAT 4317
Query: 93 FDSLLARHESLRTRLVQDGERLLQNVAPE------ARIEIRQ-DVADEQQLLARVEAEIA 145
+ ++ARHE+LRT + +Q +APE A ++R D A + + + R+ E A
Sbjct: 4318 LERIVARHEALRTHFALHEGQAIQVIAPETQGFALASHDLRALDSAAQHEAVERLAGEEA 4377
Query: 146 -RPFDLQAGPLLRVSLLQLAEDEHVLVMVQHHIISDGWSMQVMVEELVQFYAAHSQGREV 204
PFDL +GPL+R L+QL++ EH+L++ QHHI+SDGWS V++ E+ Y A SQG
Sbjct: 4378 LAPFDLSSGPLIRGRLVQLSQTEHILLVTQHHIVSDGWSTGVLLHEIGMLYRAFSQGLAD 4437
Query: 205 QLPGLPIHYADYALWQRSWMEAGEKARQLAYWQDLLGGEQPVLELPLDHPRPAQQSHCGA 264
LP L Y DYA WQR W++ Q+ +W+ L G +LELP DH RP +S+ G
Sbjct: 4438 PLPALAFQYVDYAAWQRQWLQGETLQTQVDFWRQHLSGAPALLELPTDHRRPPLRSYAGG 4497
Query: 265 SLQVHLPADLVAGIKRLAQQEGVTPFMLLLASFQTLLFRYSGQSDIRIGVPNANRNRVET 324
+ + L L AG+++L Q+ G T FM LL + +LL R+SGQ D+ IG P ANR R E
Sbjct: 4498 RVSLALSPALTAGLRQLGQRHGATLFMTLLVGWSSLLSRFSGQDDVVIGTPVANRPRSEL 4557
Query: 325 ERLIGFFVNTQVLKADLDGQMSFAELLQQAKRRSLEAQAHQDLPFEQLVVALQPERSLSH 384
E LIGFFVNT L+ +G +S A LL+Q K L A AHQDLPFEQ+V ALQP RSL+H
Sbjct: 4558 ESLIGFFVNTLALRIRPEGHLSVAALLEQVKAVMLAAHAHQDLPFEQVVEALQPPRSLAH 4617
Query: 385 NPLFQVMFNHQTDAQGGRDGQQLPGLRVAQLDWENQTTHFDLSLDTHESAEGLWAALTYA 444
+P+FQVM GG LP L + L + T FDLSL E+ GL +L YA
Sbjct: 4618 SPIFQVMLALNNTPGGGE--LSLPELSLEPLQAPHTTAQFDLSLALVEADGGLIGSLEYA 4675
Query: 445 TDLFESATIERLAQHWQNLLQAAVSAPRSRLCVLSMLDAPEQQRMLKDWN-APATVAAPH 503
+DLFE ATIER+A H Q LL+ V+ + + L +L +++++L+ +N A A
Sbjct: 4676 SDLFERATIERMAGHLQVLLEGMVADDQQSVAELPLLSCEQRRQVLESFNDTAAAYPADK 4735
Query: 504 AVHQLFEAQAREHPARQALALDDQTLSYGELNRQANRLAHYLIAQGVGPEVLVGIAVERS 563
+HQLFE QA + P A+ D +L+YGELN +ANRLAHYLI G+ P+ V I +RS
Sbjct: 4736 LIHQLFEEQAAQQPDALAVVDDAASLTYGELNARANRLAHYLIGLGIQPDDRVAICAQRS 4795
Query: 564 FAMVVSLLAVLKAGGAYVPLDPEYPRERLVHMLDDSGVRLVLTQSHLRDRLPLPADLTAL 623
MVV LL + KAGGAYVPLDP YP +RL +ML+DS VL Q+ R L +L
Sbjct: 4796 LEMVVGLLGIFKAGGAYVPLDPAYPEQRLRYMLEDSAPVAVLVQTETRRLL---GELAVP 4852
Query: 624 DIDLADAQLAQCAEHNPPT-AFEPRSLAYVIYTSGSTGKPKGVAISHAAL--------SE 674
+DL + EHNP A P+ LAYVIYTSGSTGKPKGV H A+ +
Sbjct: 4853 TLDLQEGDWEVEPEHNPVVPAITPQHLAYVIYTSGSTGKPKGVGGPHQAMVNRLYWMHNT 4912
Query: 675 FAGIAAEYSRLVADDRVLQFATLNF-DGFVEQLYPALTLGATVVLRGPQLW-DGADLYRQ 732
F G E + Q +++F D E L P L GA + + P D L++
Sbjct: 4913 FGGQRLE--------KHAQKTSISFLDSVTETLMPLL-FGAQLHIVSPLASRDPLQLWQA 4963
Query: 733 IIDQGIT-LADLPTAYWKLFLQDCLAAGPRPYGALRQVHIGGEAMPLDGPVLWR-RAGLG 790
+ + +T L +P+ +L + P R + GE +L R RA L
Sbjct: 4964 VTEHQLTRLVLVPSLLEELSRIENRQVSPEK----RLIVCSGEVF--SSSLLARTRAWLP 5017
Query: 791 HVRLLNTYGPTEATVVSSVLDCSDDNAVMGATASPIGRALPGRGLYVLDPDLNLLPVGAV 850
+LN YG +EA S+ C D+AV + PIGR + +Y+LD +P+G
Sbjct: 5018 SATILNFYGSSEAAGDSTFYLC--DSAVQAGHSLPIGRPIANTRIYLLDAHGQPVPIGVS 5075
Query: 851 GELYIASAGGLARDYLQRPSLTAERFVADPFSTLGE-RLYRTGDLARYRADGVIEYVGRV 909
GE++I AG +AR YL P LTAERF+ DPFS R+YR+GDL + ADG IEY+GR
Sbjct: 5076 GEIHIGGAG-VARGYLNMPELTAERFLDDPFSAEPTARMYRSGDLGCWLADGNIEYLGRN 5134
Query: 910 DHQVKIRGFRIELGEIEALLLAQEAVREAFLLA-----ADNQLVAYLVPAQP--LSAAEQ 962
D QVK+RGFRIELGEIE+ L A VREA ++A D +LVAYL + LSAA+
Sbjct: 5135 DDQVKLRGFRIELGEIESQLAACPGVREAVVVAREHRPGDKRLVAYLTAQEGAVLSAAQ- 5193
Query: 963 AAAGETLKATLREQLPDYMVPAHLIFLDRMPLNPNGKLDRQALPKP-DGSAVQQAWQAPV 1021
L+ L + L +YM+P+ + L R PL PNGKLDR+ALP P D + + ++AP
Sbjct: 5194 ------LREQLSQGLAEYMIPSAFVTLARFPLTPNGKLDRRALPTPKDDAYASRGYEAPA 5247
Query: 1022 TPRQQQVAAIWADILGVERVGLTHHFFELGGHSLLAMQVVSRIRQALKLEVPLKLLFEQP 1081
+ +A IW +LG+ERVG HFFELGGHSLLA+Q+VSR+RQ ++EV L+ +F +P
Sbjct: 5248 GEIEHALAEIWQTLLGLERVGRHDHFFELGGHSLLAVQLVSRLRQRFEVEVALRDVFAEP 5307
Query: 1082 RLEGFV-----AALATQDPDAPTAPALLPVGRDQPLPLSYAQERQWFLWQLEPQS-AAYH 1135
L+G A L+ Q P P L PV R+ PLPLS+AQ+R WFL QL+ + AAYH
Sbjct: 5308 TLQGLARQVANARLSAQTPLTSLTP-LTPVDRNLPLPLSWAQQRLWFLDQLDRAAGAAYH 5366
Query: 1136 IPSALRLKGQLDLGALQRSFDTLLARHESLRTHLRQERDRTVQIISPQVS---------L 1186
IP+ LRL+G+LD ALQ + D +ARHE+LRTH +T+Q+I+P
Sbjct: 5367 IPAGLRLRGRLDSDALQATLDRTVARHEALRTHFALHEGQTIQVIAPDTQGFALASHDLR 5426
Query: 1187 QIAHAEVHEAQLKARVEAEIAQPFNLEQGPLLRVSLLRIAADEHVLVLVQHHIVSDGWSM 1246
+ A HEA + E +A PF+L +GPL+R L++++ EH+L++ QHHIVSDGWS
Sbjct: 5427 ALDSAAQHEAVQQLAGEEALA-PFDLSRGPLIRGRLVQLSETEHILLVTQHHIVSDGWST 5485
Query: 1247 QLMVEELVQLYAAYSQGQVLQWPALPIQYADYAVWQRNWMEAGEKARQLAYWRDMLGGEQ 1306
+++ E+ LY A+SQG PAL QY DYA WQR W++ Q+ +WR L G
Sbjct: 5486 GVLLHEIGTLYRAFSQGLADPLPALAFQYVDYAAWQRQWLQGETLHTQVEFWRQHLSGAP 5545
Query: 1307 SVLALPFDHPRPAVQSHRGARLAFELPGALTQGLKALAKQQDVTLFMLLLASFQTLLHRY 1366
++L LP DH RP ++S+ G R++ L ALT GL+ L ++ TLFM LL + +LL R+
Sbjct: 5546 ALLELPTDHRRPLLRSYAGGRVSLALSPALTAGLRQLGQRHGATLFMTLLVGWSSLLSRF 5605
Query: 1367 SGQEEIRVGVPIANRNRSETERLIGFFVNTQVLKADLHGQMSVEQLLQQARQRALDAQAH 1426
SGQ+++ +G P+ANR RSE E LIGFFVNT L+ G +SV LL+Q + L A AH
Sbjct: 5606 SGQDDVVIGTPVANRPRSELESLIGFFVNTLALRIRPQGHLSVAALLEQVKAVMLAAHAH 5665
Query: 1427 QDLPFEQLVEALQPERSLSHNPLFQVMFNHQTDVGQAQVQQQLPNLSVEGLEWESKTAHF 1486
QDLPFEQ+VEALQP RSL H+P+FQVM G ++ LP LS+E L+ TA F
Sbjct: 5666 QDLPFEQVVEALQPPRSLGHSPIFQVMLALNNTPGGGEL--SLPELSLEPLQAPHTTAQF 5723
Query: 1487 DLDLDIQESTEGIWATLGYAQDLFEASTVQRMARHWQNLLQGMVADPRQTLSQLNLLDNT 1546
DL L + E+ G+ +L YA DLFE +T++RMA H Q LL+GMVAD +Q + +L LL
Sbjct: 5724 DLSLALVEADGGLIGSLEYASDLFERATIERMAGHLQVLLEGMVADDQQAVGELPLLSCE 5783
Query: 1547 ERQQILQRWDQSDAGFSAKRLVHELVADRAGETPEAVAVKFGEQQLTYGELDRQANRLAH 1606
+R+Q+L+ ++ + A + A L+H+L ++ + P+A+AV LTYGEL+ +ANRLAH
Sbjct: 5784 QRRQVLESFNDTAATYPAGTLLHQLFEEQVAQQPDALAVVDDAGSLTYGELNARANRLAH 5843
Query: 1607 ALIARGVGPEVRVAIAMPRSAEIMVAFLAVMKAGGVYVPLDIEYPRDRLLYMMQDSRARL 1666
LI G+ P+ RVAI RS E++V L ++KAGG YVPLD YP +RL YM++DS
Sbjct: 5844 YLIGLGIQPDDRVAICAQRSLEMVVGLLGILKAGGAYVPLDPGYPPERLRYMLEDSAPVA 5903
Query: 1667 LLTHSTVQQRLPIPDGLEALAVD-QTQAWSANDDSAPEV-VLDGDNLAYVIYTSGSTGMP 1724
+L + L L +D Q W + P V + +LAYVIYTSGSTG P
Sbjct: 5904 VLVQGETRTLL---GELAVRTLDLQEGDWEVEPEHNPVVPAITPQHLAYVIYTSGSTGKP 5960
Query: 1725 KGVAVSHGPLVAHIIATGERYETSPADCELHFMSFAFDGSHEGWMHPLINGAS-VLIRDD 1783
KGVA H +V + Y D L F FD S PL+ GA V+ R
Sbjct: 5961 KGVANQHDGVVNRLWWAQSEYRIGADDRVLQKTPFGFDVSVWEIFLPLLAGAQLVMARPG 6020
Query: 1784 SLWLPEYTYQQMHRHHVTMAVFPPVYLQQLAEHAERDGNPPKVRVYCFGGDAVAQASYDL 1843
P Y + + R ++M F P LQ RV C G+A+ A
Sbjct: 6021 GHQDPHYLMEVIERRSISMLHFVPSMLQAFVNQTPAGRCSTLKRVLC-SGEALPHALLLQ 6079
Query: 1844 AWRALKPTYLFNGYGPTETVVTPLLWKARKGDPCGAVYAPIGTLLGNRSGYVLDAQLNLQ 1903
+ L N YGPTE + W G V PIG + N Y+LDA
Sbjct: 6080 GQAHFPKSELHNLYGPTEAAIDVTAWHYVAEQDIGIV--PIGRPIANTQIYLLDAHGQPV 6137
Query: 1904 PIGVAGELYLGGEGVARGYLERPALTAERFVPDPFG-KPGSRVYRSGDLTRGRPDGGVDY 1962
PIGV+GE+++GG GVARGYL RP LTAERF+ DPF +P +R+YRSGDL R DG ++Y
Sbjct: 6138 PIGVSGEIHIGGIGVARGYLNRPELTAERFLEDPFSTEPAARMYRSGDLGRWLADGNIEY 6197
Query: 1963 LGRVDHQVKIRGFRIELGEIEARLREQDSVGETVVVAQEG-PSGKQLVAYVVPLDPLLID 2021
LGR D QVK+RG+RIELGEIE++L V E +V+A+E P K+LVAY+ + ++
Sbjct: 6198 LGRNDDQVKLRGYRIELGEIESQLAGCPGVREALVLAREHCPGDKRLVAYLTAQEGAVLS 6257
Query: 2022 DAVAQSTCREALRRALKARLPDYMVPTHLMFLERMPLTPNGKLDRKGLPRP-DVSQMQQV 2080
A LR L L +YM+P+ + L PLTPNGKLDR+ LP P D + +
Sbjct: 6258 AA--------QLREQLSQGLAEYMIPSAFVTLTHFPLTPNGKLDRRALPAPEDDAYASRG 6309
Query: 2081 YVAPQSELEQKIAAIWSDVLRLPRVGLHDNFFELGGDSIISIQVVSRARQA-GVRFTPKD 2139
Y AP E+E +A IW +L L RVG HD+FFELGG S++++Q+VS RQ V D
Sbjct: 6310 YEAPVGEIEHALAEIWQALLGLERVGRHDHFFELGGHSLLAVQLVSCLRQRFEVEVALGD 6369
Query: 2140 LFQHQTVQSLAAVAREG 2156
LF H T+ LAA G
Sbjct: 6370 LFMHPTICELAASCHSG 6386
Score = 1324 bits (3426), Expect = 0.0
Identities = 957/2634 (36%), Positives = 1390/2634 (52%), Gaps = 181/2634 (6%)
Query: 86 LAALQRAFDSLLARHESLRTRLVQDG-ERLLQNVAPEARIEIRQ------DVADEQQLLA 138
L A RA ++ARH+ LRT ++ +G + +Q V EA + + D EQQL
Sbjct: 2189 LKAFVRALQGVIARHDILRTAVLWEGLDEPVQTVWREAPLAVEALALKAADGDIEQQLQE 2248
Query: 139 RVEAEIARPFDLQAGPLLRVSLL-QLAEDEHVLVMVQHHIISDGWSMQVMVEELVQFYAA 197
R + R DL PL++++ A V +++ HH++ D +++V+ E+ A
Sbjct: 2249 RFDPRHFR-LDLTKAPLMKMAYAYDEANSRWVAILLFHHMVLDHMALEVVQHEV----QA 2303
Query: 198 HSQGREVQLPGLPIHYADYALWQRSWMEAGEKARQLAYWQDLLGG-EQPVLELPLDHP-- 254
G+ LP + Y ++ R + +A A++Q++LG +P L L
Sbjct: 2304 DLLGQAAGLPD-SVPYRNHVAQARLGVS---QAAHEAFFQEMLGQVTEPTLPFGLHDVQG 2359
Query: 255 --RPAQQSHCGASLQVHLPADLVAGIKRLAQQEGVTPFMLLLASFQTLLFRYSGQSDIRI 312
R +Q+ S ADL I+R A+ GV+ L ++ +L R SG+ D+
Sbjct: 2360 DGRDIKQARQAVS------ADLAGRIRRQARSLGVSAASLHHLAWAQVLGRTSGREDVVF 2413
Query: 313 GVPNANRNRVE--TERLIGFFVNTQVLKADLDGQMSFAELLQ--QAKRRSLEAQAHQDLP 368
G R + +R +G F+NT L ++ G+ E ++ A+ +L H L
Sbjct: 2414 GTVLLGRMQGGDGADRSLGMFINTLPLCLNV-GEQGVREGVKATHARLTALLGHEHASLA 2472
Query: 369 FEQLVVALQPERSLSHNPLFQVMFN--HQTDAQGGRDGQQLPGLRVAQLDWENQTTHFDL 426
Q A+ P PLF + N H + Q G + G + L W N+ T++ L
Sbjct: 2473 LAQRCSAIAPPL-----PLFSALLNYRHSAEPQVSEQGDRAWG-GIEVLGW-NERTNYPL 2525
Query: 427 SLDTHESAEGLWAALTYATDLFESATIERLAQHWQNLLQAAVSAPRSRLCVLSMLDAPEQ 486
+L + EG + + + ++L+ A +P S L L ML E+
Sbjct: 2526 TLAVDDLGEGFALTVQATAGIDPQRVCAYMETALESLVDALEHSPESLLRSLEMLPRSER 2585
Query: 487 QRMLKDWNAPATVAAPHA-VHQLFEAQAREHPARQALALDDQTLSYGELNRQANRLAHYL 545
Q +L++WNA A A VHQLFEAQ + P AL + +T +Y +LN +AN+LAH+L
Sbjct: 2586 Q-LLQEWNATAVDYPQGACVHQLFEAQVEKTPEAIALVFEARTFTYAQLNARANQLAHHL 2644
Query: 546 IAQGVGPEVLVGIAVERSFAMVVSLLAVLKAGGAYVPLDPEYPRERLVHMLDDSGVRLVL 605
I G+GP+ V I VERS MVV LL +LKAG AYVPLDP YP +RL +ML+DS VL
Sbjct: 2645 IGLGIGPDDRVAICVERSPEMVVGLLGILKAGAAYVPLDPAYPEQRLRYMLEDSAPAAVL 2704
Query: 606 TQSHLRDRLPLPADLTALDIDLADAQLAQCAEHNP-PTAFEPRSLAYVIYTSGSTGKPKG 664
QS R LP +L +DL A+H+P A +P LAYVIYTSGS+G+PKG
Sbjct: 2705 VQSATR---ALPGELAVPLLDLEGGCCEAEADHDPVARAVKPDHLAYVIYTSGSSGQPKG 2761
Query: 665 VAISHAALSEFAGIAAEYSRLVADDRVLQFATLNFDGFVEQLYPALTLGATVVLRGPQLW 724
V I +L +DD VL ++ +FD + + L +G T+ L + +
Sbjct: 2762 VLIEQRGFLNLMHWYLAELKLASDDAVLLVSSYSFDLTQKNILGPLLVGGTLHL-AREAF 2820
Query: 725 DGADLYRQIIDQGITLADLPTAYWKLFLQDCLAAGPRPYGALRQVHIGGEAMPLDGPVLW 784
L QI + IT +L + + + A R ++R+V +GGE P+
Sbjct: 2821 IPEVLLEQIQRERITHINLSPSAFNTLID---ANDSRQLDSIRRVVLGGE------PIQV 2871
Query: 785 RRAGL---GHVRLLNTYGPTEATVVSSVLDCSDDNAVMGATASPIGRALPGRGLYVLDPD 841
R + +N+YGPTE + V + DD ++ PIGR + +Y+LD
Sbjct: 2872 ARLEMLPEPRPEFINSYGPTECSDVVAWHRLDDDIDCYRSSVFPIGRPIANTRIYLLDAH 2931
Query: 842 LNLLPVGAVGELYIASAGGLARDYLQRPSLTAERFVADPFST-LGERLYRTGDLARYRAD 900
+P+G GE++I A G+AR YL P LTAERF+ DPFS R+YR+GDL R+ AD
Sbjct: 2932 GQPVPIGVSGEIHIGGA-GVARGYLNLPELTAERFLDDPFSAEPAARMYRSGDLGRWLAD 2990
Query: 901 GVIEYVGRVDHQVKIRGFRIELGEIEALLLAQEAVREAFLLA-----ADNQLVAYLVPAQ 955
G IEY+GR D QVKIRGFRIELGEIE+ L A VREA +L D +LVAYL +
Sbjct: 2991 GNIEYLGRNDDQVKIRGFRIELGEIESQLAACPGVREAVVLVREHRPGDKRLVAYLTARE 3050
Query: 956 --PLSAAEQAAAGETLKATLREQLPDYMVPAHLIFLDRMPLNPNGKLDRQALPKPDGSA- 1012
LSAA+ L+ L + L +YM+P+ + L R PL PNGKLDR+ALP P+ A
Sbjct: 3051 GAVLSAAQ-------LREQLSQGLAEYMIPSAFVTLARFPLTPNGKLDRRALPAPEDDAY 3103
Query: 1013 VQQAWQAPVTPRQQQVAAIWADILGVERVGLTHHFFELGGHSLLAMQVVSRIRQALKLEV 1072
+ ++AP + +A IW +LG+ERVG HFFELGGHSLLA+Q+VSR+RQ ++EV
Sbjct: 3104 ASRDYEAPAGAVEHALAQIWQTLLGLERVGRHDHFFELGGHSLLAVQLVSRLRQRFEVEV 3163
Query: 1073 PLKLLFEQPRLEGFVAALATQDPDAPTAPALL-PVGRDQPLPLSYAQERQWFLWQLE-PQ 1130
L+ +F +P L+G +A A T LL PV R+ PLPLS+AQ+R WFL QL+
Sbjct: 3164 ALRDVFAEPTLQGLARQVANARLSAQTPLTLLTPVDRNLPLPLSWAQQRLWFLDQLDRAA 3223
Query: 1131 SAAYHIPSALRLKGQLDLGALQRSFDTLLARHESLRTHLRQERDRTVQIISPQV-SLQIA 1189
AAYHIP+ LRL+G+LD ALQ + D ++ARHE+LRTH + +Q+I+P+ +A
Sbjct: 3224 GAAYHIPAGLRLRGRLDSDALQATLDRIVARHEALRTHFALHEGQAIQVIAPETQGFALA 3283
Query: 1190 HAEVHEAQLKARVEA-------EIAQPFNLEQGPLLRVSLLRIAADEHVLVLVQHHIVSD 1242
++ A+ EA E PF+L GPL+R L++++ EH+L++ QHHIVSD
Sbjct: 3284 SHDLRALDSAAQHEAVERLAREEALAPFDLSSGPLIRGRLVQLSQTEHILLVTQHHIVSD 3343
Query: 1243 GWSMQLMVEELVQLYAAYSQGQVLQWPALPIQYADYAVWQRNWMEAGEKARQLAYWRDML 1302
GWS +++ E+ LY A+SQG PAL QY DYA WQR W++ Q+ +WR L
Sbjct: 3344 GWSTGVLLHEIGTLYRAFSQGLADPLPALAFQYVDYAAWQRQWLQGETLHTQVEFWRQHL 3403
Query: 1303 GGEQSVLALPFDHPRPAVQSHRGARLAFELPGALTQGLKALAKQQDVTLFMLLLASFQTL 1362
G ++L LP DH RP ++S+ G R++ L ALT GL+ L ++ TLFM LL + +L
Sbjct: 3404 SGAPALLELPTDHRRPPLRSYAGGRVSLALSPALTAGLRQLGQRHGATLFMTLLVGWSSL 3463
Query: 1363 LHRYSGQEEIRVGVPIANRNRSETERLIGFFVNTQVLKADLHGQMSVEQLLQQARQRALD 1422
L R+SGQ+++ +G P+ANR RSE E LIGFFVNT L+ G +SV LL+Q + L
Sbjct: 3464 LSRFSGQDDVVIGTPVANRPRSELESLIGFFVNTLALRIRPQGGLSVAALLEQVKAVMLA 3523
Query: 1423 AQAHQDLPFEQLVEALQPERSLSHNPLFQVMFNHQTDVGQAQVQQQLPNLSVEGLEWESK 1482
A AHQDLPFEQ+VEALQP RSL H+P+FQVM G ++ LP LS+E L+
Sbjct: 3524 AHAHQDLPFEQVVEALQPPRSLGHSPIFQVMLALNNTPGGGEL--SLPELSLEPLQAPHT 3581
Query: 1483 TAHFDLDLDIQESTEGIWATLGYAQDLFEASTVQRMARHWQNLLQGMVADPRQTLSQLNL 1542
TA FDL L + E+ G+ +L YA DLFE +T++R+A H Q LL+GMVAD +Q +++L L
Sbjct: 3582 TAQFDLSLALVEADGGLIGSLEYASDLFERATIERIAGHLQVLLEGMVADDQQAVAELPL 3641
Query: 1543 LDNTERQQILQRWDQSDAGFSAKRLVHELVADRAGETPEAVAVKFGEQQLTYGELDRQAN 1602
L +R+Q+L+ ++ + A + A++L+H+L ++A + P+A+AV LTYGEL+ +AN
Sbjct: 3642 LSCEQRRQVLESFNDTAAAYPAEKLLHQLFEEQAAQQPDALAVVDETASLTYGELNARAN 3701
Query: 1603 RLAHALIARGVGPEVRVAIAMPRSAEIMVAFLAVMKAGGVYVPLDIEYPRDRLLYMMQDS 1662
RLAH LI G+ P+ RVAI RS E++V L ++KAGG YVPLD YP +RL YM++DS
Sbjct: 3702 RLAHYLIGLGIQPDDRVAICAQRSLEMVVGLLGILKAGGAYVPLDPGYPPERLRYMLEDS 3761
Query: 1663 RARLLLTHSTVQQRLP---IPD-GLEALAVDQ-TQAWSANDDSAPEVVLDGDNLAYVIYT 1717
+L +Q+ LP +P L+++ + T + + L AYV+YT
Sbjct: 3762 APVAVLVQEALQECLPAVNVPQVVLDSVVLSSGTGGLPCGNPDLDALGLTSRMPAYVMYT 3821
Query: 1718 SGSTGMPKGVAVSHGPLVAHIIATGERYETSPADCELHFMSFAFDGSHEGWMHPLINGAS 1777
SGS+G+PKGV + H V ++ + DC H + AFD S L+NGA
Sbjct: 3822 SGSSGVPKGVLIEHRS-VLRLVINNPYARITTEDCVAHGANTAFDASTWEIWSALLNGAK 3880
Query: 1778 VLIRDDSLWL-PEYTYQQMHRHHVT----MAVFPPVYLQQLAEHAERDGNPPKVRVYCFG 1832
+L+ + L P + VT A Y+ LA K+R G
Sbjct: 3881 LLVVSQATLLNPARLNHVLIEGGVTALWLTAGLFNEYVDVLAVAFS------KLRYLLVG 3934
Query: 1833 GDAVAQASY-DLAWRALKPTYLFNGYGPTETVVTPLLWKARK-GDPCGAVYAPIGTLLGN 1890
GD + S + RA +P +L NGYGPTET ++ D ++ PIG +GN
Sbjct: 3935 GDVLDPVSVAKVLSRAHRPRHLINGYGPTETTTFASTYEIHALSDNSRSI--PIGRPIGN 3992
Query: 1891 RSGYVLDAQLNLQPIGVAGELYLGGEGVARGYLERPALTAERFVPDPF-GKPGSRVYRSG 1949
Y+LDA PIGV+GE+++GG GVARGYL P LTAERF+ DPF +P +R+YRSG
Sbjct: 3993 TRIYLLDAHGQPVPIGVSGEIHIGGAGVARGYLNLPELTAERFLDDPFSAEPAARMYRSG 4052
Query: 1950 DLTRGRPDGGVDYLGRVDHQVKIRGFRIELGEIEARLREQDSVGETVVVAQE-GPSGKQL 2008
DL R DG ++YLGR D QVK+RGFRIELGEIE++L V E VV+ +E P K+L
Sbjct: 4053 DLGRWLADGNIEYLGRNDDQVKLRGFRIELGEIESQLAACPGVREAVVLVREHRPGDKRL 4112
Query: 2009 VAYVVPLDPLLIDDAVAQSTCREALRRALKARLPDYMVPTHLMFLERMPLTPNGKLDRKG 2068
VAY+ + L+ A LR L L +YM+P+ + L R PLTPNGKLDR+
Sbjct: 4113 VAYLTAQEGALLSAA--------QLREQLSQGLAEYMIPSAFVTLARFPLTPNGKLDRRA 4164
Query: 2069 LPRP-DVSQMQQVYVAPQSELEQKIAAIWSDVLRLPRVGLHDNFFELGGDSIISIQVVSR 2127
LP P D + + Y AP E+E +A IW +L L RVG HD+FFELGG S++++Q+VSR
Sbjct: 4165 LPAPEDDAYASRGYEAPAGEIEHALAEIWQALLGLERVGRHDHFFELGGHSLLAVQLVSR 4224
Query: 2128 ARQA-GVRFTPKDLFQHQTVQSLAAVAREGEGAVVLDQSALTGDLLLLPV---------- 2176
RQ V +D+F T+Q L AR+ A + Q+ LT L PV
Sbjct: 4225 LRQRFEVEVALRDVFAEPTLQGL---ARQVANARLSAQTPLTS---LTPVDRDLPLPLSW 4278
Query: 2177 --QQAFFADDIPRR--HHWNQSVVLQPHQALQAPLLVAALQALIVHHDALRIGFV--QGA 2230
Q+ +F D + R ++ L+ L + L A L+ ++ H+ALR F +G
Sbjct: 4279 AQQRLWFLDQLDRAAGAAYHIPAGLRLRGRLDSEALQATLERIVARHEALRTHFALHEGQ 4338
Query: 2231 A---------GWSAAYRGPQQHQAEQVLWQTTLNAVEELEALGEEAQRSLDLSEGPLLRA 2281
A G++ A H + AVE L GEEA DLS GPL+R
Sbjct: 4339 AIQVIAPETQGFALA-----SHDLRALDSAAQHEAVERL--AGEEALAPFDLSSGPLIRG 4391
Query: 2282 VLVDLADGSQRLLLVIHHLVVDGVSWRILLEDLQTAYRQVAQGAKVVLPAKTSAIRAWAE 2341
LV L+ LL+ HH+V DG S +LL ++ YR +QG LPA +A
Sbjct: 4392 RLVQLSQTEHILLVTQHHIVSDGWSTGVLLHEIGMLYRAFSQGLADPLPALAFQYVDYAA 4451
Query: 2342 RLQAYARSAALAQELAWWQTQLQGSPT--GLPGADPQASLSNRHALSVTTHLDQVFTRRL 2399
+ + + L ++ +W+ L G+P LP + L + V+ L T L
Sbjct: 4452 WQRQWLQGETLQTQVDFWRQHLSGAPALLELPTDHRRPPLRSYAGGRVSLALSPALTAGL 4511
Query: 2400 LQDAPSAYRTQINDLLLTALARVVVRWTGDASMLIRLEGHGREDLFDEIDLTRTVGWFTS 2459
Q + + LL + ++ R++G ++I R +L +G+F +
Sbjct: 4512 RQ-LGQRHGATLFMTLLVGWSSLLSRFSGQDDVVIGTPVANR----PRSELESLIGFFVN 4566
Query: 2460 LYPVKLVPTDSLAGSLKQIKEQLRAIPDKGLGFGALRYLGNAEAQQALSELPRPRITFNY 2519
+++ P L S+ + EQ++A+ L + EA Q L I F
Sbjct: 4567 TLALRIRPEGHL--SVAALLEQVKAVMLAAHAHQDLPFEQVVEALQPPRSLAHSPI-FQV 4623
Query: 2520 LGQFDGSFDGGEQEGLFVPSGDGSGAEQSGEAPLGNWLEINGQVYAGELKLNWSFSQQMF 2579
+ + + GGE + + + L L G L+ ++ +F
Sbjct: 4624 MLALNNTPGGGELSLPELSLEPLQAPHTTAQFDLSLALVEADGGLIGSLE----YASDLF 4679
Query: 2580 DEATVQRLADDYAAELKALIEHCGVNQGVTPSDFPLARLSQAQ--LDSLPVTVA 2631
+ AT++R+ A L+ L+E + + ++ PL Q + L+S T A
Sbjct: 4680 ERATIERM----AGHLQVLLEGMVADDQQSVAELPLLSCEQRRQVLESFNDTAA 4729
Score = 1229 bits (3179), Expect = 0.0
Identities = 940/2735 (34%), Positives = 1378/2735 (50%), Gaps = 198/2735 (7%)
Query: 7 IDLVSRFLRLPLEQRQQF-YQRLQSRGMSFAQ-----LPIASIREDGQMLPLSYAQERQW 60
I LV + L + LE F + +L++ AQ LP LPLS+AQ+R W
Sbjct: 1013 ISLVRQRLNVELELAALFAHPQLEALACVVAQAQNNTLPQIVQTSREARLPLSFAQQRLW 1072
Query: 61 FLWQLDPDSATYHIPGALRLQGRLDLAALQRAFDSLLARHESLRTRLVQDGERLL----- 115
FL Q++ SA YHIP LR+ G LD AALQRA + ++ARHE LRT VQ G++ +
Sbjct: 1073 FLAQMEGASAAYHIPAGLRIVGALDEAALQRALNRIVARHEVLRTTFVQTGDQAVELCIH 1132
Query: 116 --QNVAPEARIEIRQDVADEQQLLARVEAEIARPFDLQAGPLLRVSLLQLAEDEHVLVMV 173
+ P + ++ +L ++ E FDLQ GPL+R SL++L + EHVL++
Sbjct: 1133 PEETGCPLRKYDLTTHADSSSELARLMDEEAVGRFDLQQGPLIRGSLVRLGDQEHVLLLT 1192
Query: 174 QHHIISDGWSMQVMVEELVQFYAAHSQGREVQLPGLPIHYADYALWQRSWMEAGEKARQL 233
HHI+SDGWSM V+ EL YA+ Q LP L I YADYA+WQR W+ +Q
Sbjct: 1193 MHHIVSDGWSMGVLTRELGALYASGCQAEADPLPQLSIQYADYAVWQRGWLSGAVLHKQS 1252
Query: 234 AYWQDLLGGEQPVLELPLDHPRPAQQSHCGASLQVHLPADLVAGIKRLAQQEGVTPFMLL 293
YWQ L +L LP D RPAQQ + G ++ V L A L +K L+++ G T FM L
Sbjct: 1253 TYWQTALLDAPALLMLPSDRVRPAQQDYTGDAVPVVLDATLSHELKALSRRHGTTLFMTL 1312
Query: 294 LASFQTLLFRYSGQSDIRIGVPNANRNRVETERLIGFFVNTQVLKADLDGQMSFAELLQQ 353
LA + T+L R SGQ ++ IG P ANR E E LIGFFVNT L+ ++ + LL +
Sbjct: 1313 LAGWATVLSRLSGQDEVVIGSPVANRMSAEVEGLIGFFVNTLALRVNVSNDPTVETLLSR 1372
Query: 354 AKRRSLEAQAHQDLPFEQLVVALQPERSLSHNPLFQVMFNHQTDAQGGRDGQQLPGLRVA 413
K +L A HQDLPFEQ+V L+P RSLSH+PLFQ M + Q L GL +
Sbjct: 1373 VKACTLAAYEHQDLPFEQVVELLKPVRSLSHSPLFQAMLSWQNTPPA---ELALAGLELT 1429
Query: 414 QLDWENQTTHFDLSLDTHESAEGLWAALTYATDLFESATIERLAQHWQNLLQAAVSAPRS 473
LD +TT +D+SLD E + +L YAT LF+ T +R + + +L+A V R
Sbjct: 1430 LLDSVARTTKYDVSLDLAEVEGRIVGSLEYATALFDRETAQRYVAYLERVLRAMVENERQ 1489
Query: 474 RLCVLSMLDAPEQQRMLKDWNAPATVAAPHA------VHQLFEAQAREHPARQALALDDQ 527
+ + +L E++++L ++N A HA VHQLFE QA++ P AL ++
Sbjct: 1490 VVGAIELLGETERRQVLVEFN-----ATHHAWQQDLLVHQLFEQQAQQQPQALALVCGNE 1544
Query: 528 TLSYGELNRQANRLAHYLIAQGVGPEVLVGIAVERSFAMVVSLLAVLKAGGAYVPLDPEY 587
++Y +LN ++N++A L++ G+ P+ V I VERS MVV LL +LKAGGAYVPLDP Y
Sbjct: 1545 RVTYADLNERSNQVADVLLSLGIAPDDRVAICVERSVEMVVGLLGILKAGGAYVPLDPGY 1604
Query: 588 PRERLVHMLDDSGVRLVLTQSHLRDRLPLPADLTALDIDLADAQLAQCAEHNP--PTAFE 645
P ERL +ML+DS VL Q RD L L +DL A A H+ PT
Sbjct: 1605 PPERLRYMLEDSAPVAVLVQRTTRDLL---GALAMPVLDLQSVNRAAEARHDRVLPTV-T 1660
Query: 646 PRSLAYVIYTSGSTGKPKGVAISHAALSEFAGIAAEYSRLVADDRVLQFATLNFDGFVEQ 705
P+ LAYVIYTSGSTG+PKGV I H A+ A + RL +DRVLQ FD V +
Sbjct: 1661 PQHLAYVIYTSGSTGQPKGVMIEHRAIVNRLLWAQDQYRLSREDRVLQKTPFGFDVSVWE 1720
Query: 706 LYPALTLGATVVLRGP-QLWDGADLYRQIIDQGITLADLPTAYWKLFLQDCLAAGPRPYG 764
+ L GA +V+ P D L I D G+T+ + + FL AGP
Sbjct: 1721 FFLPLLAGAQLVIARPGGHQDPEYLAGLIADSGVTILHFVPSMLQSFLNQ---AGPLACS 1777
Query: 765 ALRQVHIGGEAMPLDGPVLWRRAGLGHVRLLNTYGPTEATVVSSVLDCSDDNAVMGATAS 824
LRQV GEA+P + + HV+L N YGPTEA V + C D + A
Sbjct: 1778 TLRQVFCSGEALPYSLQKHFEQR-FAHVQLHNLYGPTEAAVDVTYWHCVPD---LHAGIV 1833
Query: 825 PIGRALPGRGLYVLDPDLNLLPVGAVGELYIASAGGLARDYLQRPSLTAERFVADPFST- 883
PIGR + +Y+LDP + +PVG GE+YIA LAR YL R +LTAERFV D FS
Sbjct: 1834 PIGRPVANTRMYLLDPHMQPVPVGVCGEIYIAGI-QLARGYLNRAALTAERFVKDRFSND 1892
Query: 884 LGERLYRTGDLARYRADGVIEYVGRVDHQVKIRGFRIELGEIEALLLAQEAVREAFLLA- 942
R+YR+GDL R+ ADG IEY+GR D QVK+RGFRIELGEIEA L V EA ++A
Sbjct: 1893 PTARMYRSGDLGRWLADGNIEYLGRNDDQVKLRGFRIELGEIEAQLAGCPGVGEAVVIAR 1952
Query: 943 ----ADNQLVAYLVPAQPLSAAEQAAAGETLKATLREQLPDYMVPAHLIFLDRMPLNPNG 998
D +L+AY + A++ A +TL+A L+ LP+YMVPA + L PL PNG
Sbjct: 1953 EDTPGDKRLIAYYTTRE----AKETIAVQTLRAALQASLPEYMVPAAYVKLPGWPLTPNG 2008
Query: 999 KLDRQALPKPDGSA-VQQAWQAPVTPRQQQVAAIWADILGVERVGLTHHFFELGGHSLLA 1057
KL+R+ALP P+ A V + ++AP + +A IW ++LGVERVG HFFELGGHSLLA
Sbjct: 2009 KLNRRALPVPEADAYVSRGYEAPCGTVETALAEIWQELLGVERVGRHDHFFELGGHSLLA 2068
Query: 1058 MQVVSRIRQALKLEVPLKLLFEQPRLEGFVAALAT-QDPDAPT----------APALLPV 1106
+ ++ R+RQA L +++LF QP L F L + P P++LP+
Sbjct: 2069 VSLMGRMRQA-GLSADVRMLFAQPTLSAFAEVLGNGHQVEVPANGIVVGCTRITPSMLPL 2127
Query: 1107 G-----------RDQP---------LPLSYAQERQWFLWQLEPQSAAYHIPSALRLKGQL 1146
R P L+ QE F + Y + + L +
Sbjct: 2128 ADLSEDAIERIVRAVPGGTANVQDIYALAPLQEGVLFHHLASVEGDPYLLNTRFALPSED 2187
Query: 1147 DLGALQRSFDTLLARHESLRTHLRQE-RDRTVQIISPQ-------VSLQIAHAEVHEAQL 1198
L A R+ ++ARH+ LRT + E D VQ + + ++L+ A ++ E QL
Sbjct: 2188 HLKAFVRALQGVIARHDILRTAVLWEGLDEPVQTVWREAPLAVEALALKAADGDI-EQQL 2246
Query: 1199 KARVEAEIAQPFNLEQGPLLRVSLLRIAADEH-VLVLVQHHIVSDGWSMQLMVEELVQLY 1257
+ R + + +L + PL++++ A+ V +L+ HH+V D +++++ E+
Sbjct: 2247 QERFDPRHFR-LDLTKAPLMKMAYAYDEANSRWVAILLFHHMVLDHMALEVVQHEV---- 2301
Query: 1258 AAYSQGQVLQWPALPIQYADYAVWQRNWMEAGEKARQLAYWRDMLGGEQSVLALPFDHPR 1317
A GQ P + Y ++ R + +A A++++ML G+ + LPF
Sbjct: 2302 QADLLGQAAGLPD-SVPYRNHVAQARLGV---SQAAHEAFFQEML-GQVTEPTLPFGLHD 2356
Query: 1318 PAVQSHRGARLAFELPGALTQGLKALAKQQDVTLFMLLLASFQTLLHRYSGQEEIRVGVP 1377
+ + L ++ A+ V+ L ++ +L R SG+E++ G
Sbjct: 2357 VQGDGRDIKQARQAVSADLAGRIRRQARSLGVSAASLHHLAWAQVLGRTSGREDVVFGTV 2416
Query: 1378 IANRNR--SETERLIGFFVNTQVLKADLHGQMSVEQLLQ--QARQRALDAQAHQDLPFEQ 1433
+ R + +R +G F+NT L ++ G+ V + ++ AR AL H L Q
Sbjct: 2417 LLGRMQGGDGADRSLGMFINTLPLCLNV-GEQGVREGVKATHARLTALLGHEHASLALAQ 2475
Query: 1434 LVEALQPERSLSHNPLFQVMFNHQTDVGQAQVQQQLPNL--SVEGLEWESKTAHFDLDLD 1491
A+ P PLF + N++ + QV +Q +E L W +T ++ L L
Sbjct: 2476 RCSAIAPPL-----PLFSALLNYRHS-AEPQVSEQGDRAWGGIEVLGWNERT-NYPLTLA 2528
Query: 1492 IQESTEGIWATLGYAQDLFEASTVQRMARHWQNLLQGMVADPRQTLSQLNLLDNTERQQI 1551
+ + EG T+ + M ++L+ + P L L +L +ER Q+
Sbjct: 2529 VDDLGEGFALTVQATAGIDPQRVCAYMETALESLVDALEHSPESLLRSLEMLPRSER-QL 2587
Query: 1552 LQRWDQSDAGFSAKRLVHELVADRAGETPEAVAVKFGEQQLTYGELDRQANRLAHALIAR 1611
LQ W+ + + VH+L + +TPEA+A+ F + TY +L+ +AN+LAH LI
Sbjct: 2588 LQEWNATAVDYPQGACVHQLFEAQVEKTPEAIALVFEARTFTYAQLNARANQLAHHLIGL 2647
Query: 1612 GVGPEVRVAIAMPRSAEIMVAFLAVMKAGGVYVPLDIEYPRDRLLYMMQDSRARLLLTHS 1671
G+GP+ RVAI + RS E++V L ++KAG YVPLD YP RL YM++DS +L S
Sbjct: 2648 GIGPDDRVAICVERSPEMVVGLLGILKAGAAYVPLDPAYPEQRLRYMLEDSAPAAVLVQS 2707
Query: 1672 TVQQRLPIPDGLEALAVDQTQAWSANDDSAPEVVLDGDNLAYVIYTSGSTGMPKGVAVSH 1731
+ LP + L ++ + D + D+LAYVIYTSGS+G PKGV +
Sbjct: 2708 AT-RALPGELAVPLLDLEGGCCEAEADHDPVARAVKPDHLAYVIYTSGSSGQPKGVLIEQ 2766
Query: 1732 GPLVAHIIATGERYETSPADCELHFMSFAFDGSHEGWMHPLINGASVLIRDDSLWLPEYT 1791
+ + + + D L S++FD + + + PL+ G ++ + ++ ++PE
Sbjct: 2767 RGFLNLMHWYLAELKLASDDAVLLVSSYSFDLTQKNILGPLLVGGTLHLAREA-FIPEVL 2825
Query: 1792 YQQMHRHHVTMAVFPPVYLQQLAEHAERDGNPPKVRVYCFGGDAVAQASYDLAWRALKPT 1851
+Q+ R +T P L + A +R GG+ + A ++ +P
Sbjct: 2826 LEQIQRERITHINLSPSAFNTLID-ANDSRQLDSIRRVVLGGEPIQVARLEMLPEP-RPE 2883
Query: 1852 YLFNGYGPTETVVTPLLWKARKGDPC--GAVYAPIGTLLGNRSGYVLDAQLNLQPIGVAG 1909
++ N YGPTE + C +V+ PIG + N Y+LDA PIGV+G
Sbjct: 2884 FI-NSYGPTECSDVVAWHRLDDDIDCYRSSVF-PIGRPIANTRIYLLDAHGQPVPIGVSG 2941
Query: 1910 ELYLGGEGVARGYLERPALTAERFVPDPF-GKPGSRVYRSGDLTRGRPDGGVDYLGRVDH 1968
E+++GG GVARGYL P LTAERF+ DPF +P +R+YRSGDL R DG ++YLGR D
Sbjct: 2942 EIHIGGAGVARGYLNLPELTAERFLDDPFSAEPAARMYRSGDLGRWLADGNIEYLGRNDD 3001
Query: 1969 QVKIRGFRIELGEIEARLREQDSVGETVVVAQE-GPSGKQLVAYVVPLDPLLIDDAVAQS 2027
QVKIRGFRIELGEIE++L V E VV+ +E P K+LVAY+ + ++ A
Sbjct: 3002 QVKIRGFRIELGEIESQLAACPGVREAVVLVREHRPGDKRLVAYLTAREGAVLSAA---- 3057
Query: 2028 TCREALRRALKARLPDYMVPTHLMFLERMPLTPNGKLDRKGLPRP-DVSQMQQVYVAPQS 2086
LR L L +YM+P+ + L R PLTPNGKLDR+ LP P D + + Y AP
Sbjct: 3058 ----QLREQLSQGLAEYMIPSAFVTLARFPLTPNGKLDRRALPAPEDDAYASRDYEAPAG 3113
Query: 2087 ELEQKIAAIWSDVLRLPRVGLHDNFFELGGDSIISIQVVSRARQA-GVRFTPKDLFQHQT 2145
+E +A IW +L L RVG HD+FFELGG S++++Q+VSR RQ V +D+F T
Sbjct: 3114 AVEHALAQIWQTLLGLERVGRHDHFFELGGHSLLAVQLVSRLRQRFEVEVALRDVFAEPT 3173
Query: 2146 VQSLAAVAREGEGAVVLDQSALTGDLLLLPV------------QQAFFADDIPRR--HHW 2191
+Q L AR+ A + Q+ LT LL PV Q+ +F D + R +
Sbjct: 3174 LQGL---ARQVANARLSAQTPLT---LLTPVDRNLPLPLSWAQQRLWFLDQLDRAAGAAY 3227
Query: 2192 NQSVVLQPHQALQAPLLVAALQALIVHHDALRIGFV--QGAA---------GWSAAYRGP 2240
+ L+ L + L A L ++ H+ALR F +G A G++ A
Sbjct: 3228 HIPAGLRLRGRLDSDALQATLDRIVARHEALRTHFALHEGQAIQVIAPETQGFALA---- 3283
Query: 2241 QQHQAEQVLWQTTLNAVEELEALGEEAQRSLDLSEGPLLRAVLVDLADGSQRLLLVIHHL 2300
H + AVE L EEA DLS GPL+R LV L+ LL+ HH+
Sbjct: 3284 -SHDLRALDSAAQHEAVERLAR--EEALAPFDLSSGPLIRGRLVQLSQTEHILLVTQHHI 3340
Query: 2301 VVDGVSWRILLEDLQTAYRQVAQGAKVVLPAKTSAIRAWAERLQAYARSAALAQELAWWQ 2360
V DG S +LL ++ T YR +QG LPA +A + + + L ++ +W+
Sbjct: 3341 VSDGWSTGVLLHEIGTLYRAFSQGLADPLPALAFQYVDYAAWQRQWLQGETLHTQVEFWR 3400
Query: 2361 TQLQGSPT--GLPGADPQASLSNRHALSVTTHLDQVFTRRLLQDAPSAYRTQINDLLLTA 2418
L G+P LP + L + V+ L T L Q + + LL
Sbjct: 3401 QHLSGAPALLELPTDHRRPPLRSYAGGRVSLALSPALTAGLRQ-LGQRHGATLFMTLLVG 3459
Query: 2419 LARVVVRWTGDASMLIRLEGHGREDLFDEIDLTRTVGWFTSLYPVKLVPTDSLAGSLKQI 2478
+ ++ R++G ++I R +L +G+F + +++ P L S+ +
Sbjct: 3460 WSSLLSRFSGQDDVVIGTPVANR----PRSELESLIGFFVNTLALRIRPQGGL--SVAAL 3513
Query: 2479 KEQLRAIPDKGLGFGALRYLGNAEAQQALSELPRPRITFNYLGQFDGSFDGGEQEGLFVP 2538
EQ++A+ L + EA Q L I F + + + GGE +
Sbjct: 3514 LEQVKAVMLAAHAHQDLPFEQVVEALQPPRSLGHSPI-FQVMLALNNTPGGGELSLPELS 3572
Query: 2539 SGDGSGAEQSGEAPLGNWLEINGQVYAGELKLNWSFSQQMFDEATVQRLADDYAAELKAL 2598
+ + L L G L+ ++ +F+ AT++R+ A L+ L
Sbjct: 3573 LEPLQAPHTTAQFDLSLALVEADGGLIGSLE----YASDLFERATIERI----AGHLQVL 3624
Query: 2599 IEHCGVNQGVTPSDFPLARLSQAQ--LDSLPVTVA 2631
+E + ++ PL Q + L+S T A
Sbjct: 3625 LEGMVADDQQAVAELPLLSCEQRRQVLESFNDTAA 3659
Score = 1224 bits (3167), Expect = 0.0
Identities = 845/2377 (35%), Positives = 1242/2377 (52%), Gaps = 159/2377 (6%)
Query: 52 LSYAQERQWFLWQLDPDSATYHIPGALRLQGRLDLAALQRAFDSLLARHESLRTRLVQDG 111
LS Q+ W + D Y+I L ++G LD+ ++A + +++LR L QDG
Sbjct: 18 LSSVQQGVWLGQIANSDIPLYNIGMTLEIKGDLDIPMFEKAIKLVAKHNDALRLALFQDG 77
Query: 112 ERLLQNVAPEARIEIRQ-DVADEQQLLARVEAEI----ARPFDLQAGPLLRVSLLQLAED 166
+ Q V P I + D +D + R + + +RPF+ G L L++ +
Sbjct: 78 DIARQRVLPSVDITLALVDFSDYGDSVERAQEYLQHAFSRPFNPLEGILWEAQLVRCSAS 137
Query: 167 EHVLVMVQHHIISDGWSMQVMVEELVQFYAAHSQGREVQLPGLPIHYADYALWQRSWMEA 226
H + HH++ DG + + + + Y G + G Y+D+ ++++ +
Sbjct: 138 RHYWLGRYHHLVMDGAGVTLFCHAVEKAYNNLLVGIDAFEEGPS--YSDFLAKDQAYLNS 195
Query: 227 GEKARQLAYWQDLLGGEQP-VLELPLDHPRPAQQSHCGAS-LQVHLPADLVAGIKRLAQQ 284
R +W++ P +L+ DH A S C + ++ + DL + +A +
Sbjct: 196 PRLERDRLFWRERYAHIPPSLLQWSGDH---AVGSMCKSGHIRSTIKRDLFNAVAAVATE 252
Query: 285 EGVTPFMLLLASFQTLLFRYSGQSDIRIGVPNANRNRVETERLIGFFVNTQVLKADLDGQ 344
G++P + A R G ++ IG+P NR ++ IG F + + +D
Sbjct: 253 HGLSPVTVFFAVVSAYFSRVGGAEEVIIGMPLHNRTTARQKQTIGMFSSVIPVGVRVDPN 312
Query: 345 MSFAELLQQAKRRSLEAQAHQDLPFEQLVVALQPERSLSHNPLFQVMFNHQT-DAQGGRD 403
S EL+ H+ P +L AL S +F + + + DA
Sbjct: 313 RSLLELMGDVAAELRRCYRHEHFPIAELNRALNIGHS-RRKQIFDITLSFEKFDADFVFG 371
Query: 404 GQQLPGLRVAQLDWENQTTHFDLSLDTHESAEGLWAALTYATDLFESATIERLAQHWQNL 463
G +R+ T +++ + S E + + F +ER+ L
Sbjct: 372 GAPSKAIRMYS---GFDQTPLSIAICDYYSDEDVVVDFNFNLACFRPDEVERIRDRITLL 428
Query: 464 LQAAVSAPRSRLCVLSMLDAPEQQRMLKDWNAP-ATVAAPHAVHQLFEAQAREHPARQAL 522
L++ + + + L+++ E++++L ++NA + VHQLFE QA++ P AL
Sbjct: 429 LESVAAHESTPIGQLALMGKAERRQVLVEFNATHQALQQDLLVHQLFEQQAQQQPQALAL 488
Query: 523 ALDDQTLSYGELNRQANRLAHYLIAQGVGPEVLVGIAVERSFAMVVSLLAVLKAGGAYVP 582
D+ ++Y +LN ++N+LA L++ G+ P+ V I VERS MV LL +LKAGGAYVP
Sbjct: 489 VCGDERVTYADLNERSNQLADVLLSLGIAPDDRVAICVERSVEMVAGLLGILKAGGAYVP 548
Query: 583 LDPEYPRERLVHMLDDSGVRLVLTQSHLRDRLPLPADLTALDIDLADAQLAQCAEHNP-- 640
LDP YP ERL +ML+DS VL Q RD L L +DL A AEH+
Sbjct: 549 LDPGYPPERLRYMLEDSAPMAVLVQRTTRDLL---GALAMPVLDLQSVNRAAEAEHDCVL 605
Query: 641 PTAFEPRSLAYVIYTSGSTGKPKGVAISHAALSEFAGIAAEYSRLVADDRVLQFATLNFD 700
PT P+ LAYVIYTSGSTG+PKGV I H L E L RV A + FD
Sbjct: 606 PTV-APQHLAYVIYTSGSTGQPKGVMIEHRNLVNLVAWHCEAFNLTHRKRVSSVAGVGFD 664
Query: 701 GFVEQLYPALTLGATV-VLRGPQLWDGAD-LYRQIIDQGITLADLPTAYWKLFLQDCLAA 758
V +L+PAL +GA++ +L G L + D L Q + ++ LPT ++ A
Sbjct: 665 ACVWELWPALCVGASLSLLPGQALGNDVDALLGWWRRQELDVSFLPTPIAEI----AFAQ 720
Query: 759 GPRPYGALRQVHIGGEAM-PLDGPVLWRRAGLGHVRLLNTYGPTEATVVSSVLDCSDDNA 817
G P +L+ + IGG+ + P V L+N YGPTE TVV++ +
Sbjct: 721 GIEP-ASLQTLLIGGDRLRQFPNPD-------SRVALINNYGPTETTVVAT-------SG 765
Query: 818 VMGATASP--IGRALPGRGLYVLDPDLNLLPVGAVGELYIASAGGLARDYLQRPSLTAER 875
++ AT S IGR + +Y+LD +P+G GE+YI AG +AR YL RP LTAER
Sbjct: 766 LIDATQSVLHIGRPIANTQVYLLDAHGQPVPIGVSGEIYIGGAG-VARGYLNRPELTAER 824
Query: 876 FVADPFSTLGE-RLYRTGDLARYRADGVIEYVGRVDHQVKIRGFRIELGEIEALLLAQEA 934
F+ DPFS E R+YR+GDL R+ ADG IEY+GR D QVK+RG RIELGEIEA L
Sbjct: 825 FLDDPFSAEPEARMYRSGDLGRWLADGNIEYLGRNDDQVKLRGVRIELGEIEAQLRQIAD 884
Query: 935 VREAFLLAADN-----QLVAYLVPAQPLSAAEQAAAGETLKATLREQLPDYMVPAHLIFL 989
+R+A ++A ++ +L AY + A QA +TL+A L+ +LP+YMVPA + L
Sbjct: 885 IRDAVVIAQEDTPGEKRLTAYYT----MQEAAQAITAQTLRAALQARLPEYMVPAAYVKL 940
Query: 990 DRMPLNPNGKLDRQALPKP-DGSAVQQAWQAPVTPRQQQVAAIWADILGVERVGLTHHFF 1048
PL PNGKLDR+ALP P D + + ++AP ++ +A IW ++LGV+R G HFF
Sbjct: 941 SEWPLTPNGKLDRRALPAPGDDAYASRDYEAPAGEVERALADIWQELLGVDRAGRNDHFF 1000
Query: 1049 ELGGHSLLAMQVVSRIRQALKLEVPLKLLFEQPRLEGFVAALATQDPDAPTAPALLPVGR 1108
ELGGHSLLAM+++S +RQ L +E+ L LF P+LE +A + T P ++ R
Sbjct: 1001 ELGGHSLLAMRLISLVRQRLNVELELAALFAHPQLEALACVVAQAQNN--TLPQIVQTSR 1058
Query: 1109 DQPLPLSYAQERQWFLWQLEPQSAAYHIPSALRLKGQLDLGALQRSFDTLLARHESLRTH 1168
+ LPLS+AQ+R WFL Q+E SAAYHIP+ LR+ G LD ALQR+ + ++ARHE LRT
Sbjct: 1059 EARLPLSFAQQRLWFLAQMEGASAAYHIPAGLRIVGALDEAALQRALNRIVARHEVLRTT 1118
Query: 1169 LRQERDRTVQI-ISPQVS---LQIAHAEVH---EAQLKARVEAEIAQPFNLEQGPLLRVS 1221
Q D+ V++ I P+ + L+ H ++L ++ E F+L+QGPL+R S
Sbjct: 1119 FVQTGDQAVELCIHPEETGCPLRKYDLTTHADSSSELARLMDEEAVGRFDLQQGPLIRGS 1178
Query: 1222 LLRIAADEHVLVLVQHHIVSDGWSMQLMVEELVQLYAAYSQGQVLQWPALPIQYADYAVW 1281
L+R+ EHVL+L HHIVSDGWSM ++ EL LYA+ Q + P L IQYADYAVW
Sbjct: 1179 LVRLGDQEHVLLLTMHHIVSDGWSMGVLTRELGALYASGCQAEADPLPQLSIQYADYAVW 1238
Query: 1282 QRNWMEAGEKARQLAYWRDMLGGEQSVLALPFDHPRPAVQSHRGARLAFELPGALTQGLK 1341
QR W+ +Q YW+ L ++L LP D RPA Q + G + L L+ LK
Sbjct: 1239 QRGWLSGAVLHKQSTYWQTALLDAPALLMLPSDRVRPAQQDYTGDAVPVVLDATLSHELK 1298
Query: 1342 ALAKQQDVTLFMLLLASFQTLLHRYSGQEEIRVGVPIANRNRSETERLIGFFVNTQVLKA 1401
AL+++ TLFM LLA + T+L R SGQ+E+ +G P+ANR +E E LIGFFVNT L+
Sbjct: 1299 ALSRRHGTTLFMTLLAGWATVLSRLSGQDEVVIGSPVANRMSAEVEGLIGFFVNTLALRV 1358
Query: 1402 DLHGQMSVEQLLQQARQRALDAQAHQDLPFEQLVEALQPERSLSHNPLFQVMFNHQTDVG 1461
++ +VE LL + + L A HQDLPFEQ+VE L+P RSLSH+PLFQ M + Q
Sbjct: 1359 NVSNDPTVETLLSRVKACTLAAYEHQDLPFEQVVELLKPVRSLSHSPLFQAMLSWQ---N 1415
Query: 1462 QAQVQQQLPNLSVEGLEWESKTAHFDLDLDIQESTEGIWATLGYAQDLFEASTVQRMARH 1521
+ L L + L+ ++T +D+ LD+ E I +L YA LF+ T QR +
Sbjct: 1416 TPPAELALAGLELTLLDSVARTTKYDVSLDLAEVEGRIVGSLEYATALFDRETAQRYVAY 1475
Query: 1522 WQNLLQGMVADPRQTLSQLNLLDNTERQQILQRWDQSDAGFSAKRLVHELVADRAGETPE 1581
+ +L+ MV + RQ + + LL TER+Q+L ++ + + LVH+L +A + P+
Sbjct: 1476 LERVLRAMVENERQVVGAIELLGETERRQVLVEFNATHHAWQQDLLVHQLFEQQAQQQPQ 1535
Query: 1582 AVAVKFGEQQLTYGELDRQANRLAHALIARGVGPEVRVAIAMPRSAEIMVAFLAVMKAGG 1641
A+A+ G +++TY +L+ ++N++A L++ G+ P+ RVAI + RS E++V L ++KAGG
Sbjct: 1536 ALALVCGNERVTYADLNERSNQVADVLLSLGIAPDDRVAICVERSVEMVVGLLGILKAGG 1595
Query: 1642 VYVPLDIEYPRDRLLYMMQDSRARLLLTHSTVQQRLPIPDGLEALAVDQTQAWSANDDSA 1701
YVPLD YP +RL YM++DS +L T + L G A+ V Q+ + ++
Sbjct: 1596 AYVPLDPGYPPERLRYMLEDSAPVAVLVQRTTRDLL----GALAMPVLDLQSVNRAAEAR 1651
Query: 1702 PEVVL---DGDNLAYVIYTSGSTGMPKGVAVSHGPLVAHIIATGERYETSPADCELHFMS 1758
+ VL +LAYVIYTSGSTG PKGV + H +V ++ ++Y S D L
Sbjct: 1652 HDRVLPTVTPQHLAYVIYTSGSTGQPKGVMIEHRAIVNRLLWAQDQYRLSREDRVLQKTP 1711
Query: 1759 FAFDGSHEGWMHPLINGASVLI-RDDSLWLPEYTYQQMHRHHVTMAVFPPVYLQQLAEHA 1817
F FD S + PL+ GA ++I R PEY + VT+ F P LQ A
Sbjct: 1712 FGFDVSVWEFFLPLLAGAQLVIARPGGHQDPEYLAGLIADSGVTILHFVPSMLQSFLNQA 1771
Query: 1818 ERDGNPPKVRVYCFGGDAVAQASYDLAWRALKPTYLFNGYGPTETVVTPLLWKARKGDPC 1877
+V+C G+A+ + + L N YGPTE V W
Sbjct: 1772 GPLACSTLRQVFC-SGEALPYSLQKHFEQRFAHVQLHNLYGPTEAAVDVTYWHCVPDLHA 1830
Query: 1878 GAVYAPIGTLLGNRSGYVLDAQLNLQPIGVAGELYLGGEGVARGYLERPALTAERFVPDP 1937
G V PIG + N Y+LD + P+GV GE+Y+ G +ARGYL R ALTAERFV D
Sbjct: 1831 GIV--PIGRPVANTRMYLLDPHMQPVPVGVCGEIYIAGIQLARGYLNRAALTAERFVKDR 1888
Query: 1938 FGK-PGSRVYRSGDLTRGRPDGGVDYLGRVDHQVKIRGFRIELGEIEARLREQDSVGETV 1996
F P +R+YRSGDL R DG ++YLGR D QVK+RGFRIELGEIEA+L VGE V
Sbjct: 1889 FSNDPTARMYRSGDLGRWLADGNIEYLGRNDDQVKLRGFRIELGEIEAQLAGCPGVGEAV 1948
Query: 1997 VVAQEG-PSGKQLVAYVVPLDPLLIDDAVAQSTCREALRRALKARLPDYMVPTHLMFLER 2055
V+A+E P K+L+AY + ++ + LR AL+A LP+YMVP + L
Sbjct: 1949 VIAREDTPGDKRLIAYYTTRE-------AKETIAVQTLRAALQASLPEYMVPAAYVKLPG 2001
Query: 2056 MPLTPNGKLDRKGLPRPDV-SQMQQVYVAPQSELEQKIAAIWSDVLRLPRVGLHDNFFEL 2114
PLTPNGKL+R+ LP P+ + + + Y AP +E +A IW ++L + RVG HD+FFEL
Sbjct: 2002 WPLTPNGKLNRRALPVPEADAYVSRGYEAPCGTVETALAEIWQELLGVERVGRHDHFFEL 2061
Query: 2115 GGDSIISIQVVSRARQAGVRFTPKDLFQHQTVQSLAAVAREGEGAVVLDQSALTGDLLLL 2174
GG S++++ ++ R RQAG+ + LF T+ + A V G V + G +
Sbjct: 2062 GGHSLLAVSLMGRMRQAGLSADVRMLFAQPTLSAFAEVLGNGHQVEVPANGIVVGCTRIT 2121
Query: 2175 P--VQQAFFADDIPRR---------------------------HH----------WNQSV 2195
P + A ++D R HH N
Sbjct: 2122 PSMLPLADLSEDAIERIVRAVPGGTANVQDIYALAPLQEGVLFHHLASVEGDPYLLNTRF 2181
Query: 2196 VLQPHQALQAPLLVAALQALIVHHDALRIGFVQGAAGWSAAYRGPQQHQAEQVLWQTTLN 2255
L L+A V ALQ +I HD LR A W + Q +W+
Sbjct: 2182 ALPSEDHLKA--FVRALQGVIARHDILRT-----AVLWEGL------DEPVQTVWREAPL 2228
Query: 2256 AVEEL---EALGEEAQR----------SLDLSEGPLLR-AVLVDLADGSQRLLLVIHHLV 2301
AVE L A G+ Q+ LDL++ PL++ A D A+ +L+ HH+V
Sbjct: 2229 AVEALALKAADGDIEQQLQERFDPRHFRLDLTKAPLMKMAYAYDEANSRWVAILLFHHMV 2288
Query: 2302 VDGVSWRILLEDLQTAYRQVAQGAKVVLPAKTSAIRA 2338
+D ++ ++ ++Q A G +P + +A
Sbjct: 2289 LDHMALEVVQHEVQADLLGQAAGLPDSVPYRNHVAQA 2325
Score = 749 bits (1933), Expect = 0.0
Identities = 488/1204 (40%), Positives = 655/1204 (54%), Gaps = 59/1204 (4%)
Query: 2616 ARLS-QAQLDSL-PVTVADIEDVYPLSPMQQGMLFQSLYGEGSGD-YINQMRIDVEG-LD 2671
ARLS Q L SL P+T D PLS QQ + F +G Y + + G LD
Sbjct: 5319 ARLSAQTPLTSLTPLTPVDRNLPLPLSWAQQRLWFLDQLDRAAGAAYHIPAGLRLRGRLD 5378
Query: 2672 VPRFRQAWQAAVDSHEILRSGFLWQTEFEQPLQVVYKQMR-MPFAELDWQGRPDSSA--- 2727
+ V HE LR+ F Q +QV+ + A D + DS+A
Sbjct: 5379 SDALQATLDRTVARHEALRTHFALHEG--QTIQVIAPDTQGFALASHDLRAL-DSAAQHE 5435
Query: 2728 ALDSLAESARAQGFVLEQAPLLSLTVVRTGASRYHLIYTNHHILMDGWSGSQLFGEVLQH 2787
A+ LA F L + PL+ +V+ + + L+ T HHI+ DGWS L E+
Sbjct: 5436 AVQQLAGEEALAPFDLSRGPLIRGRLVQLSETEHILLVTQHHIVSDGWSTGVLLHEIGTL 5495
Query: 2788 YAG------EPLRAPIGRYRDYIAW----LQAQDKSVSEAFWKAQLLN----LQEPTRLA 2833
Y +PL A +Y DY AW LQ + FW+ L L+ PT
Sbjct: 5496 YRAFSQGLADPLPALAFQYVDYAAWQRQWLQGETLHTQVEFWRQHLSGAPALLELPTDHR 5555
Query: 2834 RGLQAAQSEALAVNGEHRLNLDASQTAQLKAFAQRHKVTLNTLVQSAWLLLLQHHTGQAT 2893
R L + + G L L + TA L+ QRH TL + W LL +GQ
Sbjct: 5556 RPLLRSYA-----GGRVSLALSPALTAGLRQLGQRHGATLFMTLLVGWSSLLSRFSGQDD 5610
Query: 2894 VAFGATVAGRPAQLRGIEQQVGLFINTLPVVATPDAQMTVSQWLQQIQAQNVRLREQEHT 2953
V G VA RP +E +G F+NTL + P ++V+ L+Q++A + +
Sbjct: 5611 VVIGTPVANRPRS--ELESLIGFFVNTLALRIRPQGHLSVAALLEQVKAVMLAAHAHQDL 5668
Query: 2954 PLFEI----QRWAGLGGEALFDSILVFENYPVSEALEQGAPSGLTFGAVHSLEQTHYPLT 3009
P ++ Q LG +F +L N P L S A H+ Q L
Sbjct: 5669 PFEQVVEALQPPRSLGHSPIFQVMLALNNTPGGGELSLPELSLEPLQAPHTTAQFDLSLA 5728
Query: 3010 VLLGIGDTLGMEFNYDRHAFSAAHIEQLAEHFQQLLQALAVDGAQRLATLPSLASTERET 3069
++ G +G Y F A IE++A H Q LL+ + D Q + LP L+ +R
Sbjct: 5729 LVEADGGLIG-SLEYASDLFERATIERMAGHLQVLLEGMVADDQQAVGELPLLSCEQRRQ 5787
Query: 3070 VLHAWNATAADYPLHLAVHQLIEAQVVRTPDAPALVFAGQVLSYAALNRRANRLAHRLIA 3129
VL ++N TAA YP +HQL E QV + PDA A+V L+Y LN RANRLAH LI
Sbjct: 5788 VLESFNDTAATYPAGTLLHQLFEEQVAQQPDALAVVDDAGSLTYGELNARANRLAHYLIG 5847
Query: 3130 AGVGPDVLVGLAVERSIEMVVGLLAVLKAGGAYVPLDPEYPRDRLAYMLQDSDVKLLLTQ 3189
G+ PD V + +RS+EMVVGLL +LKAGGAYVPLDP YP +RL YML+DS +L Q
Sbjct: 5848 LGIQPDDRVAICAQRSLEMVVGLLGILKAGGAYVPLDPGYPPERLRYMLEDSAPVAVLVQ 5907
Query: 3190 AH---LLEQLPIPTGLHSLVLEQGDEWLQAYAEQNPLV-TVDGENLAYVIYTSGSTGQPK 3245
LL +L + T L L++GD W + E NP+V + ++LAYVIYTSGSTG+PK
Sbjct: 5908 GETRTLLGELAVRT----LDLQEGD-W-EVEPEHNPVVPAITPQHLAYVIYTSGSTGKPK 5961
Query: 3246 GAGNRHSALTNRLCWMQHAYGLEGSDTVLQKTPFSFDVSVWEFFWPLMTGARLVVAAPGD 3305
G N+H + NRL W Q Y + D VLQKTPF FDVSVWE F PL+ GA+LV+A PG
Sbjct: 5962 GVANQHDGVVNRLWWAQSEYRIGADDRVLQKTPFGFDVSVWEIFLPLLAGAQLVMARPGG 6021
Query: 3306 HRDPARLVSLINAEHVTTLHFVPSMLQAFLQDAGVGACHSLQRIVCSGEALPVDAQQQVF 3365
H+DP L+ +I ++ LHFVPSMLQAF+ G C +L+R++CSGEALP Q
Sbjct: 6022 HQDPHYLMEVIERRSISMLHFVPSMLQAFVNQTPAGRCSTLKRVLCSGEALPHALLLQGQ 6081
Query: 3366 AKLPHAGLYNLYGPTEAAIDVTHWTCV-DEGRDAVPIGRPIANLGCYVLDGNLEPAPVGV 3424
A P + L+NLYGPTEAAIDVT W V ++ VPIGRPIAN Y+LD + +P P+GV
Sbjct: 6082 AHFPKSELHNLYGPTEAAIDVTAWHYVAEQDIGIVPIGRPIANTQIYLLDAHGQPVPIGV 6141
Query: 3425 LGELYLGGVGLARGYHRRPALTAERFVTDPFGS--GSRLYRTGDLARYRDDGVIEYAGRI 3482
GE+++GG+G+ARGY RP LTAERF+ DPF + +R+YR+GDL R+ DG IEY GR
Sbjct: 6142 SGEIHIGGIGVARGYLNRPELTAERFLEDPFSTEPAARMYRSGDLGRWLADGNIEYLGRN 6201
Query: 3483 DHQVKLRGLRIELGEIEARLLEHACVREAAVLAVD----GTHLVGYLVLQAPSEDWKAQV 3538
D QVKLRG RIELGEIE++L VREA VLA + LV YL Q + AQ+
Sbjct: 6202 DDQVKLRGYRIELGEIESQLAGCPGVREALVLAREHCPGDKRLVAYLTAQEGAVLSAAQL 6261
Query: 3539 AMHLAAQLPDYMVPAQWVVLTQMPLSPNGKLDRKALPKPE--AQGAGAYQAPQSAIEQQV 3596
L+ L +YM+P+ +V LT PL+PNGKLDR+ALP PE A + Y+AP IE +
Sbjct: 6262 REQLSQGLAEYMIPSAFVTLTHFPLTPNGKLDRRALPAPEDDAYASRGYEAPVGEIEHAL 6321
Query: 3597 AAIWRDVLGVERVGLNDNFFELGGHSLLVLMLKERIRKVSGVGLSVSQLMLNPTV-RGQV 3655
A IW+ +LG+ERVG +D+FFELGGHSLL + L +R+ V +++ L ++PT+
Sbjct: 6322 AEIWQALLGLERVGRHDHFFELGGHSLLAVQLVSCLRQRFEVEVALGDLFMHPTICELAA 6381
Query: 3656 NCLQG--DARSSLIVKLNSQTEGTPLFMFHPSFGSVHCYTAIALALREQRPVFGVICRAL 3713
+C G A + L + PLF+ H G + +A + PV+G L
Sbjct: 6382 SCHSGLNKALHPNLTTLRKEGAQHPLFLIHEGSGDIGYAQQLAKQIPSDIPVYGFSASGL 6441
Query: 3714 AEAGAEVPEWQAMVEDYAEQLLLAQPQGAFRLAGWSLGGNLAMEVAYVLEQAGRDVEFVG 3773
+ +AM Y E + QPQG +R+AGWS GG +A E+A+ L AG VEF+G
Sbjct: 6442 QSGEEHLTTIEAMASRYIEGIRHIQPQGPYRVAGWSAGGTIAYEIAHQLTGAGATVEFLG 6501
Query: 3774 WIDS 3777
+D+
Sbjct: 6502 LVDT 6505
Score = 664 bits (1714), Expect = 0.0
Identities = 458/1165 (39%), Positives = 626/1165 (53%), Gaps = 84/1165 (7%)
Query: 2540 GDGSGAEQSGEAPLGN--------WLEINGQVYAGELKLNWSFSQQMFDEATVQRLAD-- 2589
GD + A + EAP G W E+ G AG N F + RL
Sbjct: 960 GDDAYASRDYEAPAGEVERALADIWQELLGVDRAGR---NDHFFELGGHSLLAMRLISLV 1016
Query: 2590 ----DYAAELKALIEHCGVNQGVTPSDFPLARL-SQAQLDSLPVTVADIEDV-YPLSPMQ 2643
+ EL AL H P LA + +QAQ ++LP V + PLS Q
Sbjct: 1017 RQRLNVELELAALFAH--------PQLEALACVVAQAQNNTLPQIVQTSREARLPLSFAQ 1068
Query: 2644 QGMLFQSLYGEGSGDYINQMRIDVEG-LDVPRFRQAWQAAVDSHEILRSGFLWQTEFEQP 2702
Q + F + S Y + + G LD ++A V HE+LR+ F+ +
Sbjct: 1069 QRLWFLAQMEGASAAYHIPAGLRIVGALDEAALQRALNRIVARHEVLRTTFVQTGDQAVE 1128
Query: 2703 LQVVYKQMRMPFAELDWQGRPDSSAALDSLAESARAQGFVLEQAPLLSLTVVRTGASRYH 2762
L + ++ P + D DSS+ L L + F L+Q PL+ ++VR G +
Sbjct: 1129 LCIHPEETGCPLRKYDLTTHADSSSELARLMDEEAVGRFDLQQGPLIRGSLVRLGDQEHV 1188
Query: 2763 LIYTNHHILMDGWSGSQLFGEVLQHYAG------EPLRAPIGRYRDYIAW----LQAQDK 2812
L+ T HHI+ DGWS L E+ YA +PL +Y DY W L
Sbjct: 1189 LLLTMHHIVSDGWSMGVLTRELGALYASGCQAEADPLPQLSIQYADYAVWQRGWLSGAVL 1248
Query: 2813 SVSEAFWKAQLLN----LQEPT-RLARGLQAAQSEALAVNGEHRLNLDASQTAQLKAFAQ 2867
+W+ LL+ L P+ R+ Q +A+ V LDA+ + +LKA ++
Sbjct: 1249 HKQSTYWQTALLDAPALLMLPSDRVRPAQQDYTGDAVPVV------LDATLSHELKALSR 1302
Query: 2868 RHKVTLNTLVQSAWLLLLQHHTGQATVAFGATVAGR-PAQLRGIEQQVGLFINTLPVVAT 2926
RH TL + + W +L +GQ V G+ VA R A++ G+ +G F+NTL +
Sbjct: 1303 RHGTTLFMTLLAGWATVLSRLSGQDEVVIGSPVANRMSAEVEGL---IGFFVNTLALRVN 1359
Query: 2927 PDAQMTVSQWLQQIQAQNVRLREQEHTPLFEIQRWA----GLGGEALFDSILVFENYPVS 2982
TV L +++A + E + P ++ L LF ++L ++N P +
Sbjct: 1360 VSNDPTVETLLSRVKACTLAAYEHQDLPFEQVVELLKPVRSLSHSPLFQAMLSWQNTPPA 1419
Query: 2983 EALEQGAPSGLTFGAVHSLEQTHYPLTVLLGIGDTLGM---EFNYDRHAFSAAHIEQLAE 3039
E A +GL + S+ +T V L + + G Y F ++
Sbjct: 1420 EL----ALAGLELTLLDSVARTT-KYDVSLDLAEVEGRIVGSLEYATALFDRETAQRYVA 1474
Query: 3040 HFQQLLQALAVDGAQRLATLPSLASTERETVLHAWNATAADYPLHLAVHQLIEAQVVRTP 3099
+ +++L+A+ + Q + + L TER VL +NAT + L VHQL E Q + P
Sbjct: 1475 YLERVLRAMVENERQVVGAIELLGETERRQVLVEFNATHHAWQQDLLVHQLFEQQAQQQP 1534
Query: 3100 DAPALVFAGQVLSYAALNRRANRLAHRLIAAGVGPDVLVGLAVERSIEMVVGLLAVLKAG 3159
A ALV + ++YA LN R+N++A L++ G+ PD V + VERS+EMVVGLL +LKAG
Sbjct: 1535 QALALVCGNERVTYADLNERSNQVADVLLSLGIAPDDRVAICVERSVEMVVGLLGILKAG 1594
Query: 3160 GAYVPLDPEYPRDRLAYMLQDSDVKLLLTQA---HLLEQLPIPTGLHSLVLEQGDEWLQA 3216
GAYVPLDP YP +RL YML+DS +L Q LL L +P L L+ + +A
Sbjct: 1595 GAYVPLDPGYPPERLRYMLEDSAPVAVLVQRTTRDLLGALAMPV----LDLQSVNRAAEA 1650
Query: 3217 YAEQNPLVTVDGENLAYVIYTSGSTGQPKGAGNRHSALTNRLCWMQHAYGLEGSDTVLQK 3276
++ L TV ++LAYVIYTSGSTGQPKG H A+ NRL W Q Y L D VLQK
Sbjct: 1651 RHDR-VLPTVTPQHLAYVIYTSGSTGQPKGVMIEHRAIVNRLLWAQDQYRLSREDRVLQK 1709
Query: 3277 TPFSFDVSVWEFFWPLMTGARLVVAAPGDHRDPARLVSLINAEHVTTLHFVPSMLQAFLQ 3336
TPF FDVSVWEFF PL+ GA+LV+A PG H+DP L LI VT LHFVPSMLQ+FL
Sbjct: 1710 TPFGFDVSVWEFFLPLLAGAQLVIARPGGHQDPEYLAGLIADSGVTILHFVPSMLQSFLN 1769
Query: 3337 DAGVGACHSLQRIVCSGEALPVDAQQQVFAKLPHAGLYNLYGPTEAAIDVTHWTCV-DEG 3395
AG AC +L+++ CSGEALP Q+ + H L+NLYGPTEAA+DVT+W CV D
Sbjct: 1770 QAGPLACSTLRQVFCSGEALPYSLQKHFEQRFAHVQLHNLYGPTEAAVDVTYWHCVPDLH 1829
Query: 3396 RDAVPIGRPIANLGCYVLDGNLEPAPVGVLGELYLGGVGLARGYHRRPALTAERFVTDPF 3455
VPIGRP+AN Y+LD +++P PVGV GE+Y+ G+ LARGY R ALTAERFV D F
Sbjct: 1830 AGIVPIGRPVANTRMYLLDPHMQPVPVGVCGEIYIAGIQLARGYLNRAALTAERFVKDRF 1889
Query: 3456 GSG--SRLYRTGDLARYRDDGVIEYAGRIDHQVKLRGLRIELGEIEARLLEHACVREAAV 3513
+ +R+YR+GDL R+ DG IEY GR D QVKLRG RIELGEIEA+L V EA V
Sbjct: 1890 SNDPTARMYRSGDLGRWLADGNIEYLGRNDDQVKLRGFRIELGEIEAQLAGCPGVGEAVV 1949
Query: 3514 LAVDGT----HLVGYLVLQAPSEDWKAQ-VAMHLAAQLPDYMVPAQWVVLTQMPLSPNGK 3568
+A + T L+ Y + E Q + L A LP+YMVPA +V L PL+PNGK
Sbjct: 1950 IAREDTPGDKRLIAYYTTREAKETIAVQTLRAALQASLPEYMVPAAYVKLPGWPLTPNGK 2009
Query: 3569 LDRKALPKPEAQG--AGAYQAPQSAIEQQVAAIWRDVLGVERVGLNDNFFELGGHSLLVL 3626
L+R+ALP PEA + Y+AP +E +A IW+++LGVERVG +D+FFELGGHSLL +
Sbjct: 2010 LNRRALPVPEADAYVSRGYEAPCGTVETALAEIWQELLGVERVGRHDHFFELGGHSLLAV 2069
Query: 3627 MLKERIRKVSGVGLSVSQLMLNPTV 3651
L R+R+ +G+ V L PT+
Sbjct: 2070 SLMGRMRQ-AGLSADVRMLFAQPTL 2093
Score = 608 bits (1569), Expect = e-176
Identities = 417/1098 (37%), Positives = 575/1098 (52%), Gaps = 49/1098 (4%)
Query: 2616 ARLSQAQLDSLPVTVADIEDVYPLSPMQQGMLFQSLYGEGSGD-YINQMRIDVEG-LDVP 2673
ARLS AQ +T D + PLS QQ + F +G Y + + G LD
Sbjct: 4254 ARLS-AQTPLTSLTPVDRDLPLPLSWAQQRLWFLDQLDRAAGAAYHIPAGLRLRGRLDSE 4312
Query: 2674 RFRQAWQAAVDSHEILRSGFLWQTEFEQPLQVVYKQMR-MPFAELDWQGRPDSSA---AL 2729
+ + V HE LR+ F Q +QV+ + + A D + DS+A A+
Sbjct: 4313 ALQATLERIVARHEALRTHFALHEG--QAIQVIAPETQGFALASHDLRAL-DSAAQHEAV 4369
Query: 2730 DSLAESARAQGFVLEQAPLLSLTVVRTGASRYHLIYTNHHILMDGWSGSQLFGEVLQHYA 2789
+ LA F L PL+ +V+ + + L+ T HHI+ DGWS L E+ Y
Sbjct: 4370 ERLAGEEALAPFDLSSGPLIRGRLVQLSQTEHILLVTQHHIVSDGWSTGVLLHEIGMLYR 4429
Query: 2790 G------EPLRAPIGRYRDYIAW----LQAQDKSVSEAFWKAQLLNLQEPTRLARGLQAA 2839
+PL A +Y DY AW LQ + FW+ L L +
Sbjct: 4430 AFSQGLADPLPALAFQYVDYAAWQRQWLQGETLQTQVDFWRQHLSGAPALLELPTDHRRP 4489
Query: 2840 QSEALAVNGEHRLNLDASQTAQLKAFAQRHKVTLNTLVQSAWLLLLQHHTGQATVAFGAT 2899
+ A G L L + TA L+ QRH TL + W LL +GQ V G
Sbjct: 4490 PLRSYA-GGRVSLALSPALTAGLRQLGQRHGATLFMTLLVGWSSLLSRFSGQDDVVIGTP 4548
Query: 2900 VAGRPAQLRGIEQQVGLFINTLPVVATPDAQMTVSQWLQQIQAQNVRLREQEHTPLFEI- 2958
VA RP +E +G F+NTL + P+ ++V+ L+Q++A + + P ++
Sbjct: 4549 VANRPRS--ELESLIGFFVNTLALRIRPEGHLSVAALLEQVKAVMLAAHAHQDLPFEQVV 4606
Query: 2959 ---QRWAGLGGEALFDSILVFENYPVSEALEQGAPSGLTFGAVHSLEQTHYPLTVLLGIG 3015
Q L +F +L N P L S A H+ Q L ++ G
Sbjct: 4607 EALQPPRSLAHSPIFQVMLALNNTPGGGELSLPELSLEPLQAPHTTAQFDLSLALVEADG 4666
Query: 3016 DTLGMEFNYDRHAFSAAHIEQLAEHFQQLLQALAVDGAQRLATLPSLASTERETVLHAWN 3075
+G Y F A IE++A H Q LL+ + D Q +A LP L+ +R VL ++N
Sbjct: 4667 GLIG-SLEYASDLFERATIERMAGHLQVLLEGMVADDQQSVAELPLLSCEQRRQVLESFN 4725
Query: 3076 ATAADYPLHLAVHQLIEAQVVRTPDAPALVFAGQVLSYAALNRRANRLAHRLIAAGVGPD 3135
TAA YP +HQL E Q + PDA A+V L+Y LN RANRLAH LI G+ PD
Sbjct: 4726 DTAAAYPADKLIHQLFEEQAAQQPDALAVVDDAASLTYGELNARANRLAHYLIGLGIQPD 4785
Query: 3136 VLVGLAVERSIEMVVGLLAVLKAGGAYVPLDPEYPRDRLAYMLQDSDVKLLLTQA---HL 3192
V + +RS+EMVVGLL + KAGGAYVPLDP YP RL YML+DS +L Q L
Sbjct: 4786 DRVAICAQRSLEMVVGLLGIFKAGGAYVPLDPAYPEQRLRYMLEDSAPVAVLVQTETRRL 4845
Query: 3193 LEQLPIPTGLHSLVLEQGDEWLQAYAEQNPLV-TVDGENLAYVIYTSGSTGQPKGAGNRH 3251
L +L +PT L L++GD W + E NP+V + ++LAYVIYTSGSTG+PKG G H
Sbjct: 4846 LGELAVPT----LDLQEGD-W-EVEPEHNPVVPAITPQHLAYVIYTSGSTGKPKGVGGPH 4899
Query: 3252 SALTNRLCWMQHAYGLEGSDTVLQKTPFSFDVSVWEFFWPLMTGARLVVAAPGDHRDPAR 3311
A+ NRL WM + +G + + QKT SF SV E PL+ GA+L + +P RDP +
Sbjct: 4900 QAMVNRLYWMHNTFGGQRLEKHAQKTSISFLDSVTETLMPLLFGAQLHIVSPLASRDPLQ 4959
Query: 3312 LVSLINAEHVTTLHFVPSMLQAFLQDAGVGACHSLQRIVCSGEALPVDAQQQVFAKLPHA 3371
L + +T L VPS+L+ + + IVCSGE + A LP A
Sbjct: 4960 LWQAVTEHQLTRLVLVPSLLEELSRIENRQVSPEKRLIVCSGEVFSSSLLARTRAWLPSA 5019
Query: 3372 GLYNLYGPTEAAIDVTHWTC--VDEGRDAVPIGRPIANLGCYVLDGNLEPAPVGVLGELY 3429
+ N YG +EAA D T + C + ++PIGRPIAN Y+LD + +P P+GV GE++
Sbjct: 5020 TILNFYGSSEAAGDSTFYLCDSAVQAGHSLPIGRPIANTRIYLLDAHGQPVPIGVSGEIH 5079
Query: 3430 LGGVGLARGYHRRPALTAERFVTDPFGS--GSRLYRTGDLARYRDDGVIEYAGRIDHQVK 3487
+GG G+ARGY P LTAERF+ DPF + +R+YR+GDL + DG IEY GR D QVK
Sbjct: 5080 IGGAGVARGYLNMPELTAERFLDDPFSAEPTARMYRSGDLGCWLADGNIEYLGRNDDQVK 5139
Query: 3488 LRGLRIELGEIEARLLEHACVREAAVLAVD----GTHLVGYLVLQAPSEDWKAQVAMHLA 3543
LRG RIELGEIE++L VREA V+A + LV YL Q + AQ+ L+
Sbjct: 5140 LRGFRIELGEIESQLAACPGVREAVVVAREHRPGDKRLVAYLTAQEGAVLSAAQLREQLS 5199
Query: 3544 AQLPDYMVPAQWVVLTQMPLSPNGKLDRKALPKP--EAQGAGAYQAPQSAIEQQVAAIWR 3601
L +YM+P+ +V L + PL+PNGKLDR+ALP P +A + Y+AP IE +A IW+
Sbjct: 5200 QGLAEYMIPSAFVTLARFPLTPNGKLDRRALPTPKDDAYASRGYEAPAGEIEHALAEIWQ 5259
Query: 3602 DVLGVERVGLNDNFFELGGHSLLVLMLKERIRKVSGVGLSVSQLMLNPTVRGQVNCLQGD 3661
+LG+ERVG +D+FFELGGHSLL + L R+R+ V +++ + PT++G + +
Sbjct: 5260 TLLGLERVGRHDHFFELGGHSLLAVQLVSRLRQRFEVEVALRDVFAEPTLQGLARQV-AN 5318
Query: 3662 ARSSLIVKLNSQTEGTPL 3679
AR S L S T TP+
Sbjct: 5319 ARLSAQTPLTSLTPLTPV 5336
Score = 573 bits (1476), Expect = e-166
Identities = 404/1113 (36%), Positives = 596/1113 (53%), Gaps = 71/1113 (6%)
Query: 2608 VTPSDFPLARLSQAQLD----SLPVTVADIEDVYPLSPMQQGMLFQSLYGEGSGDYINQM 2663
+TPS PLA LS+ ++ ++P A+++D+Y L+P+Q+G+LF L Y+
Sbjct: 2120 ITPSMLPLADLSEDAIERIVRAVPGGTANVQDIYALAPLQEGVLFHHLASVEGDPYLLNT 2179
Query: 2664 RIDVEGLD-VPRFRQAWQAAVDSHEILRSGFLWQTEFEQPLQVVYKQMRMPFAELDWQGR 2722
R + D + F +A Q + H+ILR+ LW+ ++P+Q V+++ + L +
Sbjct: 2180 RFALPSEDHLKAFVRALQGVIARHDILRTAVLWEG-LDEPVQTVWREAPLAVEALALKAA 2238
Query: 2723 PDSSAALDSLAESARAQGFVLE--QAPLLSLTVVRTGA-SRYHLIYTNHHILMDGWS--- 2776
L E + F L+ +APL+ + A SR+ I HH+++D +
Sbjct: 2239 DGDIE--QQLQERFDPRHFRLDLTKAPLMKMAYAYDEANSRWVAILLFHHMVLDHMALEV 2296
Query: 2777 -GSQLFGEVLQHYAGEPLRAPIGRYRDYIAWLQ-AQDKSVSEAFWKAQLLNLQEPTRLAR 2834
++ ++L AG P P YR+++A + ++ EAF++ L + EPT L
Sbjct: 2297 VQHEVQADLLGQAAGLPDSVP---YRNHVAQARLGVSQAAHEAFFQEMLGQVTEPT-LPF 2352
Query: 2835 GLQAAQSEALAVNGEHRLNLDASQTAQLKAFAQRHKVTLNTLVQSAWLLLLQHHTGQATV 2894
GL Q + + + R + A +++ A+ V+ +L AW +L +G+ V
Sbjct: 2353 GLHDVQGDGRDIK-QARQAVSADLAGRIRRQARSLGVSAASLHHLAWAQVLGRTSGREDV 2411
Query: 2895 AFGATVAGRPAQLRGIEQQVGLFINTLPVVATPDAQMTVSQWLQQIQAQNVRLREQEHTP 2954
FG + GR G ++ +G+FINTLP+ Q V + ++ A+ L EH
Sbjct: 2412 VFGTVLLGRMQGGDGADRSLGMFINTLPLCLNVGEQ-GVREGVKATHARLTALLGHEHAS 2470
Query: 2955 LFEIQRWAGLGGEA-LFDSILVFENYPVSEALEQGAPSGLTFGAVHSL---EQTHYPLTV 3010
L QR + + LF ++L + + + EQG + +G + L E+T+YPLT+
Sbjct: 2471 LALAQRCSAIAPPLPLFSALLNYRHSAEPQVSEQGDRA---WGGIEVLGWNERTNYPLTL 2527
Query: 3011 LLGIGDTLGMEFNYDRHAFSAAHIEQLAEHFQQLLQALAVDGAQR-----LATLPSLAST 3065
+ D LG F A + +++ + + L++L VD + L +L L +
Sbjct: 2528 AV---DDLGEGFALTVQATAGIDPQRVCAYMETALESL-VDALEHSPESLLRSLEMLPRS 2583
Query: 3066 ERETVLHAWNATAADYPLHLAVHQLIEAQVVRTPDAPALVFAGQVLSYAALNRRANRLAH 3125
ER+ +L WNATA DYP VHQL EAQV +TP+A ALVF + +YA LN RAN+LAH
Sbjct: 2584 ERQ-LLQEWNATAVDYPQGACVHQLFEAQVEKTPEAIALVFEARTFTYAQLNARANQLAH 2642
Query: 3126 RLIAAGVGPDVLVGLAVERSIEMVVGLLAVLKAGGAYVPLDPEYPRDRLAYMLQDSDVKL 3185
LI G+GPD V + VERS EMVVGLL +LKAG AYVPLDP YP RL YML+DS
Sbjct: 2643 HLIGLGIGPDDRVAICVERSPEMVVGLLGILKAGAAYVPLDPAYPEQRLRYMLEDSAPAA 2702
Query: 3186 LLTQAHLLEQLPIPTGLHSLVLEQGDEWLQAYAEQNPLV-TVDGENLAYVIYTSGSTGQP 3244
+L Q+ LP + L LE G +A A+ +P+ V ++LAYVIYTSGS+GQP
Sbjct: 2703 VLVQS-ATRALPGELAVPLLDLEGG--CCEAEADHDPVARAVKPDHLAYVIYTSGSSGQP 2759
Query: 3245 KGAGNRHSALTNRLCWMQHAYGLEGSDTVLQKTPFSFDVSVWEFFWPLMTGARLVVAAPG 3304
KG N + W L D VL + +SFD++ PL+ G L +A
Sbjct: 2760 KGVLIEQRGFLNLMHWYLAELKLASDDAVLLVSSYSFDLTQKNILGPLLVGGTLHLAR-- 2817
Query: 3305 DHRDPARLVSLINAEHVTTLHFVPSMLQAFLQDAGVGACHSLQRIVCSGEALPVDAQQQV 3364
+ P L+ I E +T ++ PS + S++R+V GE P+ +
Sbjct: 2818 EAFIPEVLLEQIQRERITHINLSPSAFNTLIDANDSRQLDSIRRVVLGGE--PIQVARLE 2875
Query: 3365 FAKLPHAGLYNLYGPTEAAIDVTHWTCVDEGRD-----AVPIGRPIANLGCYVLDGNLEP 3419
P N YGPTE + DV W +D+ D PIGRPIAN Y+LD + +P
Sbjct: 2876 MLPEPRPEFINSYGPTECS-DVVAWHRLDDDIDCYRSSVFPIGRPIANTRIYLLDAHGQP 2934
Query: 3420 APVGVLGELYLGGVGLARGYHRRPALTAERFVTDPFGS--GSRLYRTGDLARYRDDGVIE 3477
P+GV GE+++GG G+ARGY P LTAERF+ DPF + +R+YR+GDL R+ DG IE
Sbjct: 2935 VPIGVSGEIHIGGAGVARGYLNLPELTAERFLDDPFSAEPAARMYRSGDLGRWLADGNIE 2994
Query: 3478 YAGRIDHQVKLRGLRIELGEIEARLLEHACVREAAVLAVD----GTHLVGYLVLQAPSED 3533
Y GR D QVK+RG RIELGEIE++L VREA VL + LV YL + +
Sbjct: 2995 YLGRNDDQVKIRGFRIELGEIESQLAACPGVREAVVLVREHRPGDKRLVAYLTAREGAVL 3054
Query: 3534 WKAQVAMHLAAQLPDYMVPAQWVVLTQMPLSPNGKLDRKALPKPE--AQGAGAYQAPQSA 3591
AQ+ L+ L +YM+P+ +V L + PL+PNGKLDR+ALP PE A + Y+AP A
Sbjct: 3055 SAAQLREQLSQGLAEYMIPSAFVTLARFPLTPNGKLDRRALPAPEDDAYASRDYEAPAGA 3114
Query: 3592 IEQQVAAIWRDVLGVERVGLNDNFFELGGHSLLVLMLKERIRKVSGVGLSVSQLMLNPTV 3651
+E +A IW+ +LG+ERVG +D+FFELGGHSLL + L R+R+ V +++ + PT
Sbjct: 3115 VEHALAQIWQTLLGLERVGRHDHFFELGGHSLLAVQLVSRLRQRFEVEVALRDVFAEPT- 3173
Query: 3652 RGQVNCLQGDARSSLIVKLNSQTEGTPLFMFHP 3684
LQG AR +L++Q TPL + P
Sbjct: 3174 ------LQGLARQVANARLSAQ---TPLTLLTP 3197
Score = 547 bits (1410), Expect = e-158
Identities = 399/1099 (36%), Positives = 551/1099 (50%), Gaps = 52/1099 (4%)
Query: 2616 ARLSQAQLDSLPVTVADIEDVYPLSPMQQGMLFQSLYGEGSGD-YINQMRIDVEG-LDVP 2673
ARLS AQ +T D PLS QQ + F +G Y + + G LD
Sbjct: 3184 ARLS-AQTPLTLLTPVDRNLPLPLSWAQQRLWFLDQLDRAAGAAYHIPAGLRLRGRLDSD 3242
Query: 2674 RFRQAWQAAVDSHEILRSGFLWQTEFEQPLQVVYKQMR-MPFAELDWQGRPDSSA---AL 2729
+ V HE LR+ F Q +QV+ + + A D + DS+A A+
Sbjct: 3243 ALQATLDRIVARHEALRTHFALHEG--QAIQVIAPETQGFALASHDLRAL-DSAAQHEAV 3299
Query: 2730 DSLAESARAQGFVLEQAPLLSLTVVRTGASRYHLIYTNHHILMDGWSGSQLFGEVLQHYA 2789
+ LA F L PL+ +V+ + + L+ T HHI+ DGWS L E+ Y
Sbjct: 3300 ERLAREEALAPFDLSSGPLIRGRLVQLSQTEHILLVTQHHIVSDGWSTGVLLHEIGTLYR 3359
Query: 2790 G------EPLRAPIGRYRDYIAW----LQAQDKSVSEAFWKAQLLNLQEPTRLARGLQAA 2839
+PL A +Y DY AW LQ + FW+ L L +
Sbjct: 3360 AFSQGLADPLPALAFQYVDYAAWQRQWLQGETLHTQVEFWRQHLSGAPALLELPTDHRRP 3419
Query: 2840 QSEALAVNGEHRLNLDASQTAQLKAFAQRHKVTLNTLVQSAWLLLLQHHTGQATVAFGAT 2899
+ A G L L + TA L+ QRH TL + W LL +GQ V G
Sbjct: 3420 PLRSYA-GGRVSLALSPALTAGLRQLGQRHGATLFMTLLVGWSSLLSRFSGQDDVVIGTP 3478
Query: 2900 VAGRPAQLRGIEQQVGLFINTLPVVATPDAQMTVSQWLQQIQAQNVRLREQEHTPLFEI- 2958
VA RP +E +G F+NTL + P ++V+ L+Q++A + + P ++
Sbjct: 3479 VANRPRS--ELESLIGFFVNTLALRIRPQGGLSVAALLEQVKAVMLAAHAHQDLPFEQVV 3536
Query: 2959 ---QRWAGLGGEALFDSILVFENYPVSEALEQGAPSGLTFGAVHSLEQTHYPLTVLLGIG 3015
Q LG +F +L N P L S A H+ Q L ++ G
Sbjct: 3537 EALQPPRSLGHSPIFQVMLALNNTPGGGELSLPELSLEPLQAPHTTAQFDLSLALVEADG 3596
Query: 3016 DTLGMEFNYDRHAFSAAHIEQLAEHFQQLLQALAVDGAQRLATLPSLASTERETVLHAWN 3075
+G Y F A IE++A H Q LL+ + D Q +A LP L+ +R VL ++N
Sbjct: 3597 GLIG-SLEYASDLFERATIERIAGHLQVLLEGMVADDQQAVAELPLLSCEQRRQVLESFN 3655
Query: 3076 ATAADYPLHLAVHQLIEAQVVRTPDAPALVFAGQVLSYAALNRRANRLAHRLIAAGVGPD 3135
TAA YP +HQL E Q + PDA A+V L+Y LN RANRLAH LI G+ PD
Sbjct: 3656 DTAAAYPAEKLLHQLFEEQAAQQPDALAVVDETASLTYGELNARANRLAHYLIGLGIQPD 3715
Query: 3136 VLVGLAVERSIEMVVGLLAVLKAGGAYVPLDPEYPRDRLAYMLQDSDVKLLLTQAHLLEQ 3195
V + +RS+EMVVGLL +LKAGGAYVPLDP YP +RL YML+DS +L Q L E
Sbjct: 3716 DRVAICAQRSLEMVVGLLGILKAGGAYVPLDPGYPPERLRYMLEDSAPVAVLVQEALQEC 3775
Query: 3196 LP---IP-TGLHSLVLEQGDEWLQAYAEQNPLVTVDGENLAYVIYTSGSTGQPKGAGNRH 3251
LP +P L S+VL G L + + AYV+YTSGS+G PKG H
Sbjct: 3776 LPAVNVPQVVLDSVVLSSGTGGLPCGNPDLDALGLTSRMPAYVMYTSGSSGVPKGVLIEH 3835
Query: 3252 SALTNRLCWMQHAYGLEGSDTVLQKTPFSFDVSVWEFFWPLMTGARLVVAAPGDHRDPAR 3311
++ RL + D V +FD S WE + L+ GA+L+V + +PAR
Sbjct: 3836 RSVL-RLVINNPYARITTEDCVAHGANTAFDASTWEIWSALLNGAKLLVVSQATLLNPAR 3894
Query: 3312 LVSLINAEHVTTLHFVPSMLQAFLQDAGVGACHSLQRIVCSGEAL-PVDAQQQVFAKLPH 3370
L ++ VT L + ++ V A L+ ++ G+ L PV + +
Sbjct: 3895 LNHVLIEGGVTALWLTAGLFNEYVDVLAV-AFSKLRYLLVGGDVLDPVSVAKVLSRAHRP 3953
Query: 3371 AGLYNLYGPTEAAIDVTHWT--CVDEGRDAVPIGRPIANLGCYVLDGNLEPAPVGVLGEL 3428
L N YGPTE + + + + ++PIGRPI N Y+LD + +P P+GV GE+
Sbjct: 3954 RHLINGYGPTETTTFASTYEIHALSDNSRSIPIGRPIGNTRIYLLDAHGQPVPIGVSGEI 4013
Query: 3429 YLGGVGLARGYHRRPALTAERFVTDPFGS--GSRLYRTGDLARYRDDGVIEYAGRIDHQV 3486
++GG G+ARGY P LTAERF+ DPF + +R+YR+GDL R+ DG IEY GR D QV
Sbjct: 4014 HIGGAGVARGYLNLPELTAERFLDDPFSAEPAARMYRSGDLGRWLADGNIEYLGRNDDQV 4073
Query: 3487 KLRGLRIELGEIEARLLEHACVREAAVLAVD----GTHLVGYLVLQAPSEDWKAQVAMHL 3542
KLRG RIELGEIE++L VREA VL + LV YL Q + AQ+ L
Sbjct: 4074 KLRGFRIELGEIESQLAACPGVREAVVLVREHRPGDKRLVAYLTAQEGALLSAAQLREQL 4133
Query: 3543 AAQLPDYMVPAQWVVLTQMPLSPNGKLDRKALPKPE--AQGAGAYQAPQSAIEQQVAAIW 3600
+ L +YM+P+ +V L + PL+PNGKLDR+ALP PE A + Y+AP IE +A IW
Sbjct: 4134 SQGLAEYMIPSAFVTLARFPLTPNGKLDRRALPAPEDDAYASRGYEAPAGEIEHALAEIW 4193
Query: 3601 RDVLGVERVGLNDNFFELGGHSLLVLMLKERIRKVSGVGLSVSQLMLNPTVRGQVNCLQG 3660
+ +LG+ERVG +D+FFELGGHSLL + L R+R+ V +++ + PT LQG
Sbjct: 4194 QALLGLERVGRHDHFFELGGHSLLAVQLVSRLRQRFEVEVALRDVFAEPT-------LQG 4246
Query: 3661 DARSSLIVKLNSQTEGTPL 3679
AR +L++QT T L
Sbjct: 4247 LARQVANARLSAQTPLTSL 4265
Score = 500 bits (1288), Expect = e-144
Identities = 405/1358 (29%), Positives = 629/1358 (46%), Gaps = 81/1358 (5%)
Query: 1114 LSYAQERQWFLWQLEPQSAAYHIPSALRLKGQLDLGALQRSFDTLLARHESLRTHLRQER 1173
LS Q+ W Y+I L +KG LD+ +++ + +++LR L Q+
Sbjct: 18 LSSVQQGVWLGQIANSDIPLYNIGMTLEIKGDLDIPMFEKAIKLVAKHNDALRLALFQDG 77
Query: 1174 DRTVQIISPQVSLQIAHAEVHE-----AQLKARVEAEIAQPFNLEQGPLLRVSLLRIAAD 1228
D Q + P V + +A + + + + ++ ++PFN +G L L+R +A
Sbjct: 78 DIARQRVLPSVDITLALVDFSDYGDSVERAQEYLQHAFSRPFNPLEGILWEAQLVRCSAS 137
Query: 1229 EHVLVLVQHHIVSDGWSMQLMVEELVQLYA-------AYSQGQVLQWPALPIQYADYAVW 1281
H + HH+V DG + L + + Y A+ +G Y+D+
Sbjct: 138 RHYWLGRYHHLVMDGAGVTLFCHAVEKAYNNLLVGIDAFEEGP---------SYSDFLAK 188
Query: 1282 QRNWMEAGEKARQLAYWRDMLGG-EQSVLALPFDHPRPAVQSH-RGARLAFELPGALTQG 1339
+ ++ + R +WR+ S+L DH AV S + + + L
Sbjct: 189 DQAYLNSPRLERDRLFWRERYAHIPPSLLQWSGDH---AVGSMCKSGHIRSTIKRDLFNA 245
Query: 1340 LKALAKQQDVTLFMLLLASFQTLLHRYSGQEEIRVGVPIANRNRSETERLIGFFVNTQVL 1399
+ A+A + ++ + A R G EE+ +G+P+ NR + ++ IG F + +
Sbjct: 246 VAAVATEHGLSPVTVFFAVVSAYFSRVGGAEEVIIGMPLHNRTTARQKQTIGMFSSVIPV 305
Query: 1400 KADLHGQMSVEQLLQQARQRALDAQAHQDLPFEQLVEALQPERSLSHNPLFQVMFNHQTD 1459
+ S+ +L+ H+ P +L AL ++ H+ Q+ F+
Sbjct: 306 GVRVDPNRSLLELMGDVAAELRRCYRHEHFPIAELNRAL----NIGHSRRKQI-FDITLS 360
Query: 1460 VGQAQVQQQLPNLSVEGLEWESKTAHFDLDLDIQE--STEGIWATLGYAQDLFEASTVQR 1517
+ + + S L + I + S E + + F V+R
Sbjct: 361 FEKFDADFVFGGAPSKAIRMYSGFDQTPLSIAICDYYSDEDVVVDFNFNLACFRPDEVER 420
Query: 1518 MARHWQNLLQGMVADPRQTLSQLNLLDNTERQQILQRWDQSDAGFSAKRLVHELVADRAG 1577
+ LL+ + A + QL L+ ER+Q+L ++ + LVH+L +A
Sbjct: 421 IRDRITLLLESVAAHESTPIGQLALMGKAERRQVLVEFNATHQALQQDLLVHQLFEQQAQ 480
Query: 1578 ETPEAVAVKFGEQQLTYGELDRQANRLAHALIARGVGPEVRVAIAMPRSAEIMVAFLAVM 1637
+ P+A+A+ G++++TY +L+ ++N+LA L++ G+ P+ RVAI + RS E++ L ++
Sbjct: 481 QQPQALALVCGDERVTYADLNERSNQLADVLLSLGIAPDDRVAICVERSVEMVAGLLGIL 540
Query: 1638 KAGGVYVPLDIEYPRDRLLYMMQDSRARLLLTHSTVQQRLPIPDGLEALAVDQTQAWSAN 1697
KAGG YVPLD YP +RL YM++DS +L T + L G A+ V Q+ +
Sbjct: 541 KAGGAYVPLDPGYPPERLRYMLEDSAPMAVLVQRTTRDLL----GALAMPVLDLQSVNRA 596
Query: 1698 DDSAPEVVLDG---DNLAYVIYTSGSTGMPKGVAVSHGPLVAHIIATGERYETSPADCEL 1754
++ + VL +LAYVIYTSGSTG PKGV + H LV + E + +
Sbjct: 597 AEAEHDCVLPTVAPQHLAYVIYTSGSTGQPKGVMIEHRNLVNLVAWHCEAFNLTHRKRVS 656
Query: 1755 HFMSFAFDGS-HEGWMHPLINGASVLIRDDSLWLPEYTYQQMHRHHVTMAVFPPVYLQQL 1813
FD E W + + L+ +L R F P +
Sbjct: 657 SVAGVGFDACVWELWPALCVGASLSLLPGQALGNDVDALLGWWRRQELDVSFLPT---PI 713
Query: 1814 AEHAERDG-NPPKVRVYCFGGDAVAQASYDLAWRALKPTYLFNGYGPTETVVTPLLWKAR 1872
AE A G P ++ GGD + Q + AL N YGPTET V A
Sbjct: 714 AEIAFAQGIEPASLQTLLIGGDRLRQFPNPDSRVAL-----INNYGPTETTVV-----AT 763
Query: 1873 KG--DPCGAVYAPIGTLLGNRSGYVLDAQLNLQPIGVAGELYLGGEGVARGYLERPALTA 1930
G D +V IG + N Y+LDA PIGV+GE+Y+GG GVARGYL RP LTA
Sbjct: 764 SGLIDATQSVLH-IGRPIANTQVYLLDAHGQPVPIGVSGEIYIGGAGVARGYLNRPELTA 822
Query: 1931 ERFVPDPFG-KPGSRVYRSGDLTRGRPDGGVDYLGRVDHQVKIRGFRIELGEIEARLREQ 1989
ERF+ DPF +P +R+YRSGDL R DG ++YLGR D QVK+RG RIELGEIEA+LR+
Sbjct: 823 ERFLDDPFSAEPEARMYRSGDLGRWLADGNIEYLGRNDDQVKLRGVRIELGEIEAQLRQI 882
Query: 1990 DSVGETVVVAQEG-PSGKQLVAYVVPLDPLLIDDAVAQSTCREALRRALKARLPDYMVPT 2048
+ + VV+AQE P K+L AY + AQ+ + LR AL+ARLP+YMVP
Sbjct: 883 ADIRDAVVIAQEDTPGEKRLTAYYTMQE-------AAQAITAQTLRAALQARLPEYMVPA 935
Query: 2049 HLMFLERMPLTPNGKLDRKGLPRP-DVSQMQQVYVAPQSELEQKIAAIWSDVLRLPRVGL 2107
+ L PLTPNGKLDR+ LP P D + + Y AP E+E+ +A IW ++L + R G
Sbjct: 936 AYVKLSEWPLTPNGKLDRRALPAPGDDAYASRDYEAPAGEVERALADIWQELLGVDRAGR 995
Query: 2108 HDNFFELGGDSIISIQVVSRARQA-GVRFTPKDLFQHQTVQSLAAVAREGEGAVVLDQSA 2166
+D+FFELGG S+++++++S RQ V LF H +++LA V + + L Q
Sbjct: 996 NDHFFELGGHSLLAMRLISLVRQRLNVELELAALFAHPQLEALACVVAQAQNNT-LPQIV 1054
Query: 2167 LTGDLLLLPVQQA-----FFADDIPRRHHWNQSVVLQPHQALQAPLLVAALQALIVHHDA 2221
T LP+ A F A ++ L+ AL L AL ++ H+
Sbjct: 1055 QTSREARLPLSFAQQRLWFLAQMEGASAAYHIPAGLRIVGALDEAALQRALNRIVARHEV 1114
Query: 2222 LRIGFVQGAAGWSAAYRGPQQHQAEQVLWQTTLNAVEELEA---LGEEAQRSLDLSEGPL 2278
LR FVQ P++ + T +A E + EEA DL +GPL
Sbjct: 1115 LRTTFVQTGDQAVELCIHPEETGCPLRKYDLTTHADSSSELARLMDEEAVGRFDLQQGPL 1174
Query: 2279 LRAVLVDLADGSQRLLLVIHHLVVDGVSWRILLEDLQTAYRQVAQGAKVVLPAKTSAIRA 2338
+R LV L D LLL +HH+V DG S +L +L Y Q LP +
Sbjct: 1175 IRGSLVRLGDQEHVLLLTMHHIVSDGWSMGVLTRELGALYASGCQAEADPLPQLSIQYAD 1234
Query: 2339 WAERLQAYARSAALAQELAWWQTQLQGSPT--GLPGADPQASLSNRHALSVTTHLDQVFT 2396
+A + + A L ++ +WQT L +P LP + + + +V LD +
Sbjct: 1235 YAVWQRGWLSGAVLHKQSTYWQTALLDAPALLMLPSDRVRPAQQDYTGDAVPVVLDATLS 1294
Query: 2397 RRLLQDAPSAYRTQINDLLLTALARVVVRWTGDASMLI 2434
L+ + T + LL A V+ R +G ++I
Sbjct: 1295 HE-LKALSRRHGTTLFMTLLAGWATVLSRLSGQDEVVI 1331
Score = 489 bits (1259), Expect = e-140
Identities = 360/1066 (33%), Positives = 544/1066 (51%), Gaps = 60/1066 (5%)
Query: 2637 YPLSPMQQGMLFQSLYGEGSGDYINQMRIDVEG-LDVPRFRQAWQAAVDSHEILRSGFLW 2695
Y LS +QQG+ + Y M ++++G LD+P F +A + ++ LR
Sbjct: 16 YELSSVQQGVWLGQIANSDIPLYNIGMTLEIKGDLDIPMFEKAIKLVAKHNDALRLALFQ 75
Query: 2696 QTEFEQPLQVVYKQMRMPFAELDWQGRPDSSAALDSLAESARAQGFVLEQAPLLSLTVVR 2755
+ + Q V + + A +D+ DS + A ++ F + L +VR
Sbjct: 76 DGDIAR--QRVLPSVDITLALVDFSDYGDSVERAQEYLQHAFSRPFNPLEGILWEAQLVR 133
Query: 2756 TGASRYHLIYTNHHILMDGWSGSQLFGEVLQHYAGEPLRAPIG--------RYRDYIAWL 2807
ASR++ + HH++MDG +G LF ++ L +G Y D++A
Sbjct: 134 CSASRHYWLGRYHHLVMDG-AGVTLFCHAVEKAYNNLL---VGIDAFEEGPSYSDFLAKD 189
Query: 2808 QAQDKSV----SEAFWKAQLLNLQEPTRLARGLQAAQSEALAVNGEHRLNLDASQTAQLK 2863
QA S FW+ + ++ G A S + +G R + +
Sbjct: 190 QAYLNSPRLERDRLFWRERYAHIPPSLLQWSGDHAVGS--MCKSGHIRSTIKRDLFNAVA 247
Query: 2864 AFAQRHKVTLNTLVQSAWLLLLQHHTGQATVAFGATVAGRPAQLRGIEQQVGLFINTLPV 2923
A A H ++ T+ + G V G + R + +Q +G+F + +PV
Sbjct: 248 AVATEHGLSPVTVFFAVVSAYFSRVGGAEEVIIGMPLHNRTTARQ--KQTIGMFSSVIPV 305
Query: 2924 VATPDAQMTVSQWLQQIQAQNVRLREQEHTPLFEIQRWAGLGG---EALFDSILVFENYP 2980
D ++ + + + A+ R EH P+ E+ R +G + +FD L FE +
Sbjct: 306 GVRVDPNRSLLELMGDVAAELRRCYRHEHFPIAELNRALNIGHSRRKQIFDITLSFEKFD 365
Query: 2981 VSEALEQGAPSGLTFGAVHSLEQTHYPLTVLLGIGDT-LGMEFNYDRHAFSAAHIEQLAE 3039
++ + GAPS +QT + + D + ++FN++ F +E++ +
Sbjct: 366 -ADFVFGGAPSK-AIRMYSGFDQTPLSIAICDYYSDEDVVVDFNFNLACFRPDEVERIRD 423
Query: 3040 HFQQLLQALAVDGAQRLATLPSLASTERETVLHAWNATAADYPLHLAVHQLIEAQVVRTP 3099
LL+++A + + L + ER VL +NAT L VHQL E Q + P
Sbjct: 424 RITLLLESVAAHESTPIGQLALMGKAERRQVLVEFNATHQALQQDLLVHQLFEQQAQQQP 483
Query: 3100 DAPALVFAGQVLSYAALNRRANRLAHRLIAAGVGPDVLVGLAVERSIEMVVGLLAVLKAG 3159
A ALV + ++YA LN R+N+LA L++ G+ PD V + VERS+EMV GLL +LKAG
Sbjct: 484 QALALVCGDERVTYADLNERSNQLADVLLSLGIAPDDRVAICVERSVEMVAGLLGILKAG 543
Query: 3160 GAYVPLDPEYPRDRLAYMLQDSDVKLLLTQ---AHLLEQLPIPTGLHSLVLEQGDEWLQA 3216
GAYVPLDP YP +RL YML+DS +L Q LL L +P VL+ A
Sbjct: 544 GAYVPLDPGYPPERLRYMLEDSAPMAVLVQRTTRDLLGALAMP------VLDLQSVNRAA 597
Query: 3217 YAEQN-PLVTVDGENLAYVIYTSGSTGQPKGAGNRHSALTNRLCWMQHAYGLEGSDTVLQ 3275
AE + L TV ++LAYVIYTSGSTGQPKG H L N + W A+ L V
Sbjct: 598 EAEHDCVLPTVAPQHLAYVIYTSGSTGQPKGVMIEHRNLVNLVAWHCEAFNLTHRKRVSS 657
Query: 3276 KTPFSFDVSVWEFFWPLMTGARLVVAAPGD--HRDPARLVSLINAEHVTTLHFVPSMLQA 3333
FD VWE + L GA L + PG D L+ + + + F+P+ +
Sbjct: 658 VAGVGFDACVWELWPALCVGASLSL-LPGQALGNDVDALLGWWRRQEL-DVSFLPTPIAE 715
Query: 3334 FLQDAGVGACHSLQRIVCSGEALPVDAQQQVFAKLPHAGLYNLYGPTEAAIDVTHWTCVD 3393
G+ SLQ ++ G+ L +Q L N YGPTE + T +D
Sbjct: 716 IAFAQGIEPA-SLQTLLIGGDRL-----RQFPNPDSRVALINNYGPTETTVVATS-GLID 768
Query: 3394 EGRDAVPIGRPIANLGCYVLDGNLEPAPVGVLGELYLGGVGLARGYHRRPALTAERFVTD 3453
+ + IGRPIAN Y+LD + +P P+GV GE+Y+GG G+ARGY RP LTAERF+ D
Sbjct: 769 ATQSVLHIGRPIANTQVYLLDAHGQPVPIGVSGEIYIGGAGVARGYLNRPELTAERFLDD 828
Query: 3454 PFGS--GSRLYRTGDLARYRDDGVIEYAGRIDHQVKLRGLRIELGEIEARLLEHACVREA 3511
PF + +R+YR+GDL R+ DG IEY GR D QVKLRG+RIELGEIEA+L + A +R+A
Sbjct: 829 PFSAEPEARMYRSGDLGRWLADGNIEYLGRNDDQVKLRGVRIELGEIEAQLRQIADIRDA 888
Query: 3512 AVLAVDGT----HLVGYLVLQAPSEDWKAQ-VAMHLAAQLPDYMVPAQWVVLTQMPLSPN 3566
V+A + T L Y +Q ++ AQ + L A+LP+YMVPA +V L++ PL+PN
Sbjct: 889 VVIAQEDTPGEKRLTAYYTMQEAAQAITAQTLRAALQARLPEYMVPAAYVKLSEWPLTPN 948
Query: 3567 GKLDRKALPKP--EAQGAGAYQAPQSAIEQQVAAIWRDVLGVERVGLNDNFFELGGHSLL 3624
GKLDR+ALP P +A + Y+AP +E+ +A IW+++LGV+R G ND+FFELGGHSLL
Sbjct: 949 GKLDRRALPAPGDDAYASRDYEAPAGEVERALADIWQELLGVDRAGRNDHFFELGGHSLL 1008
Query: 3625 VLMLKERIRKVSGVGLSVSQLMLNPTVRGQVNCLQGDARSSLIVKL 3670
+ L +R+ V L ++ L +P + + C+ A+++ + ++
Sbjct: 1009 AMRLISLVRQRLNVELELAALFAHPQLEA-LACVVAQAQNNTLPQI 1053