Pairwise Alignments
Query, 3949 a.a., peptide synthase from Pseudomonas simiae WCS417
Subject, 2883 a.a., Non-ribosomal peptide synthase:Amino acid adenylation from Pseudomonas syringae pv. syringae B728a
Score = 2660 bits (6896), Expect = 0.0
Identities = 1468/2881 (50%), Positives = 1890/2881 (65%), Gaps = 107/2881 (3%)
Query: 1112 LPLSYAQERQWFLWQLEPQSAAYHIPSALRLKGQLDLGALQRSFDTLLARHESLRTHLRQ 1171
+PLSYAQ+R FLWQ+EP +AAY++P A+RL G LD AL + D L+ RHE+LRT
Sbjct: 57 IPLSYAQQRMLFLWQMEPGNAAYNVPMAVRLNGALDRQALSAALDRLVQRHETLRTRFVS 116
Query: 1172 ERDRTVQIISPQVSLQIAHAEVHEAQLKARVEAEIAQPFNLEQGPLLRVSLLRIAADEHV 1231
E Q I Q + + A A+++ +V AE+ QPF+L G LLRV L +++ EHV
Sbjct: 117 EDGVFYQEILEQAKVALEFASAAPAEIEQQVRAELQQPFDLLSGTLLRVKLFQLSESEHV 176
Query: 1232 LVLVQHHIVSDGWSMQLMVEELVQLYAAYSQGQVLQWPALPIQYADYAVWQRNWMEAGEK 1291
L + HH+VSDGWS ++++ E VQLY A GQ P L +QYADYA+WQR W+EAGE
Sbjct: 177 LTVCMHHVVSDGWSGEVLIREFVQLYQAQVSGQPAPLPELAVQYADYAIWQRAWLEAGEG 236
Query: 1292 ARQLAYWRDMLGGEQSVLALPFDHPRPAVQSHRGARLAFELPGALTQGLKALAKQQDVTL 1351
RQL YW+ LG E +L+LP DHPRP SHRGA + +LP L+ LK+LA+ TL
Sbjct: 237 ERQLDYWKQQLGSEHPLLSLPLDHPRPLQPSHRGAMVRVDLPQQLSVQLKSLARNNGQTL 296
Query: 1352 FMLLLASFQTLLHRYSGQEEIRVGVPIANRNRSETERLIGFFVNTQVLKADLHGQMSVEQ 1411
FM+ LA+ +L R+SGQ +IR+G P A R RSE E LIGFF+NTQVL+ + + S +
Sbjct: 297 FMVTLAALSVVLSRFSGQSDIRIGAPNAGRTRSELEGLIGFFINTQVLRVQVDERQSFAE 356
Query: 1412 LLQQARQRALDAQAHQDLPFEQLVEALQPERSLSHNPLFQVMFNHQTDVGQAQVQQQLPN 1471
LL Q +Q AQ+HQ+LPFE LV+AL PER+ HNPLFQ N + Q++
Sbjct: 357 LLDQVKQVVTGAQSHQELPFEHLVDALAPERNPGHNPLFQFKINQHVLAADGR-GQRVSG 415
Query: 1472 LSVEGLEWESKTAHFDLDLDIQESTEGIWATLGYAQDLFEASTVQRMARHWQNLLQGMVA 1531
L+V+ +S A FDL D ++ +GI YA DLFEA TV+R+A +++LQ +V+
Sbjct: 416 LTVDEFPMDSSDARFDLAFDFTDTPDGIRGYFTYATDLFEAQTVERIADALRSVLQALVS 475
Query: 1532 DPRQTLSQ---LNLLDNTERQQ------ILQRWDQSDAGFSAKRLVHELVADRAGETPEA 1582
D + L+ L E+ Q L W Q G A R G+T
Sbjct: 476 DTDRRLADHPHAISLPVAEQSQDFACPDFLSLWQQ---GLRAGR----------GKT--- 519
Query: 1583 VAVKFGEQQLTYGELDRQANRLAHALIARGVGPEVRVAIAMPRSAEIMVAFLAVMKAGGV 1642
A++ G+Q L++ EL+ ++NR A L A+ + P + VA+ + RS E +V+ LAV+K G V
Sbjct: 520 -ALRVGQQVLSFDELETRSNRFARYLHAQDIKPGMTVALCLDRSVEWVVSLLAVLKLGAV 578
Query: 1643 YVPLDIEYPRDRLLYMMQDSRARLLLTHSTVQQRLPIPDGLEALAVDQTQAWSANDDSAP 1702
Y+PLD P +RL + +DS A +LL ++ + LA D W+A D A
Sbjct: 579 YLPLDSAQPAERLQQLARDSGA-VLLVYARDDDKAARLGVCPVLAFDAA-LWAAVDSQAL 636
Query: 1703 EVVLDGDNLAYVIYTSGSTGMPKGVAVSHGPLVAHIIATGERYETSPADCELHFMSFAFD 1762
+V + AY+IYTSGSTG PKGV +SHG L ++ ER S + A D
Sbjct: 637 DVRVLPGQAAYIIYTSGSTGQPKGVVISHGALANYVQGVLERLALSDGASMAMVSTVAAD 696
Query: 1763 GSHEGWMHPLINGASV-LIRDDSLWLPEYTYQQMHRHHVTMAVFPPVYLQQLAEHAERDG 1821
H L +G ++ L+ + + P+ + M H V + P +LQ L + A
Sbjct: 697 LGHTLLFGALASGRALHLLSHEQAFDPDGFARYMAEHQVDVLKIVPSHLQGLLQAA---- 752
Query: 1822 NPPKV---RVYCFGGDAVAQASYDLAWRALKP-TYLFNGYGPTETVVTPLLWKARKGDPC 1877
NP V +V GG+A A A + RALKP + N YGPTET V L + G
Sbjct: 753 NPADVLPGQVLILGGEASAWALVEQV-RALKPGCRVINHYGPTETTVGILTHEVA-GPLS 810
Query: 1878 GAVYAPIGTLLGNRSGYVLDAQLNLQPIGVAGELYLGGEGVARGYLERPALTAERFVPDP 1937
P+G L N VLDA LN VAGELYLGG G+A+GYL R A+TAERFVPDP
Sbjct: 811 ACRSVPVGQPLANGKARVLDAYLNPVAERVAGELYLGGRGLAQGYLGRAAMTAERFVPDP 870
Query: 1938 FGKPGSRVYRSGDLTRGRPDGGVDYLGRVDHQVKIRGFRIELGEIEARLREQDSVGETVV 1997
G R+YR+GD R DG ++YLGR D QVKIRG+R+E GE+ L+ ++V + VV
Sbjct: 871 DAN-GQRLYRAGDRARW-VDGVLEYLGRADDQVKIRGYRVEPGEVGQLLQTLENVADAVV 928
Query: 1998 VAQEGPSGK---QLVAYVVPLDPLLIDDAVAQSTCREALRRALKARLPDYMVPTHLMFLE 2054
+AQ S + QLVAY V A S E+LR L ARLP+Y+VP +M LE
Sbjct: 929 LAQPLESDETRLQLVAYCVA--------AAGASLNVESLRGQLAARLPEYLVPAQIMLLE 980
Query: 2055 RMPLTPNGKLDRKGLPRPDVSQMQQVYVAPQSELEQKIAAIWSDVLRLPRVGLHDNFFEL 2114
R+P+T NGKLD++ LP P V ++Q Y AP E+E+K+AA+W+DVL+L +VG DNFFEL
Sbjct: 981 RLPVTANGKLDKRALPMPGV--VKQRYTAPVGEIEEKLAAVWADVLKLEQVGSTDNFFEL 1038
Query: 2115 GGDSIISIQVVSRARQAGVRFTPKDLFQHQTVQSLAAVAR--EGEGAVVLDQSALTGDLL 2172
GGDSI+S+Q+++RA++ G++ +PK LF+ QT+ LA+VA+ + + A V +Q ++G L
Sbjct: 1039 GGDSILSLQIIARAKRQGIKLSPKQLFEKQTIGQLASVAKLIQKKPAAVAEQ--ISGSLP 1096
Query: 2173 LLPVQQAFFADDIPRRHHWNQSVVLQPHQALQAPLLVAALQALIVHHDALRIGFVQGAAG 2232
LLP+Q FF DIP R HWNQ+++L+P Q L+A L +AL AL+ HDALR+GF + +
Sbjct: 1097 LLPIQARFFELDIPERQHWNQALMLKPLQTLEAAHLQSALTALVEQHDALRLGFTRQSGQ 1156
Query: 2233 WSAAYRGPQQHQAEQVLWQTTLNAVEELEALGEEAQRSLDLSEGPLLRAVLVDLADGSQR 2292
W A + P ++LW L+++E L L EAQRSLDL GPLLRAVL++L G QR
Sbjct: 1157 WQATFGAPN---TRELLWAHELDSIERLPELAAEAQRSLDLKNGPLLRAVLINLPQGEQR 1213
Query: 2293 LLLVIHHLVVDGVSWRILLEDLQTAYRQVAQGAKVVLPAKTSAIRAWAERLQAYARSAAL 2352
LLLVIHHLVVDGVSWR+LLEDLQ AY +A G +LPAKTS+++AWAE LQAYA S AL
Sbjct: 1214 LLLVIHHLVVDGVSWRVLLEDLQQAYIALAAGQPALLPAKTSSLQAWAEHLQAYAHSPAL 1273
Query: 2353 AQELAWWQTQLQGSPTGLPGADPQASLSNRHALSVTTHLDQVFTRRLLQDAPSAYRTQIN 2412
QEL +WQTQLQ LP P +HALSV T L+ TR+LLQDAP+AYRTQIN
Sbjct: 1274 EQELGYWQTQLQDVSDALPCDHPHGGQQQQHALSVVTQLNSELTRQLLQDAPAAYRTQIN 1333
Query: 2413 DLLLTALARVVVRWTGDASMLIRLEGHGREDLFDEIDLTRTVGWFTSLYPVKLVPTDSLA 2472
DLLLTAL+RVV RWT LIRLEGHGREDLFD +DL+RTVGWF+++YPV+L P SLA
Sbjct: 1334 DLLLTALSRVVSRWTARPHALIRLEGHGREDLFDALDLSRTVGWFSNVYPVRLTPQASLA 1393
Query: 2473 GSLKQIKEQLRAIPDKGLGFGALRYLGNAEAQQALSELPRPRITFNYLGQFDGSFDGGEQ 2532
S+ IKEQLRA+PDKG+G+GALRYLG A+Q L LP I FNYLGQFDGSFD
Sbjct: 1394 DSIMTIKEQLRAVPDKGVGYGALRYLGRESARQTLQALPLGSIVFNYLGQFDGSFDA--P 1451
Query: 2533 EGLFVPSGDGSGAEQSGEAPLGNWLEINGQVYAGELKLNWSFSQQMFDEATVQRLADDYA 2592
E LF PS D SGA QS +APL + INGQVYAGEL+L+W+FS +F+ TV RLAD+YA
Sbjct: 1452 EALFTPSADSSGASQSADAPLAAPISINGQVYAGELRLSWTFSGAVFERETVHRLADEYA 1511
Query: 2593 AELKALIEHCGVNQGV---TPSDFPLARLSQAQLDSLPVTVADIEDVYPLSPMQQGMLFQ 2649
AEL+ LI HC N+GV TPSDFPLARLSQ+QL LP+ IED+YPL+PMQQGMLF
Sbjct: 1512 AELQQLIAHC-TNEGVAGATPSDFPLARLSQSQLSRLPIAAGQIEDLYPLAPMQQGMLFH 1570
Query: 2650 SLYGEGSGDYINQMRIDVEGLDVPRFRQAWQAAVDSHEILRSGFLWQTEFEQPLQVVYKQ 2709
+L+ + SG+YINQMRI+V GLDVPRFR AWQA +D+HE+LRS F+ + + LQVV +
Sbjct: 1571 TLFEQESGNYINQMRIEVSGLDVPRFRAAWQATLDAHEVLRSAFI--SHLQPALQVVLRD 1628
Query: 2710 MRMPFAELDWQGRPDSSAALDSLAESARAQGFVLEQAPLLSLTVVRTGASRYHLIYTNHH 2769
+RMPF ELD +G+ SS +D A++ R QGF L Q PLL L VVRTG + LIYT+HH
Sbjct: 1629 VRMPFVELDARGQ--SSDWIDQWADADRQQGFDLAQGPLLRLAVVRTGEQSHQLIYTSHH 1686
Query: 2770 ILMDGWSGSQLFGEVLQHYAGEPLRAPIGRYRDYIAWLQAQDKSVSEAFWKAQLLNLQEP 2829
ILMDGWS S+L GEVLQ Y+G+ L + RYRDYI WLQ QD +SE FW QL L EP
Sbjct: 1687 ILMDGWSSSRLLGEVLQRYSGQTLPRQVSRYRDYIEWLQRQDAGLSERFWTGQLARLDEP 1746
Query: 2830 TRLARGLQAAQSEALAVNGEHRLNLDASQTAQLKAFAQRHKVTLNTLVQSAWLLLLQHHT 2889
TRL + +A S +G++ +DA T QL FA+ +VTLNTLVQSAWLL+LQ +T
Sbjct: 1747 TRLVQAFKAPDSGQ--GHGDYLHLIDAENTRQLSEFAREQRVTLNTLVQSAWLLVLQRYT 1804
Query: 2890 GQATVAFGATVAGRPAQLRGIEQQVGLFINTLPVVATPDAQMTVSQWLQQIQAQNVRLRE 2949
GQ++V FGATVAGRPA L G+E+Q+GLFINTLPV+A+P A+ V++W+QQ+QAQN+ LRE
Sbjct: 1805 GQSSVTFGATVAGRPADLPGVEEQLGLFINTLPVIASPRAEQRVAEWVQQVQAQNIALRE 1864
Query: 2950 QEHTPLFEIQRWAGLGGEALFDSILVFENYPVSEALEQGAPSGLTFGAVHSLEQTHYPLT 3009
EHTPL+EIQRWA GEALFD+ILVFENYPVSEAL+Q AP GL FG +H+ EQTHYPLT
Sbjct: 1865 HEHTPLYEIQRWARSAGEALFDTILVFENYPVSEALQQAAPPGLVFGGLHTQEQTHYPLT 1924
Query: 3010 VLLGIGDTLGMEFNYDRHAFSAAHIEQLAEHFQQLLQALAVDGAQRLATLPSLASTERET 3069
+++ +G+TL + F+Y R AFS H+ QL+ HFQQ+LQAL D L L L E++
Sbjct: 1925 LVVNLGETLSLRFSYAREAFSEQHMAQLSAHFQQVLQALTHDAQAALGELALLNDNEQQQ 1984
Query: 3070 VLHAWNATAADYPLHLAVHQLIEAQVVRTPDAPALVFAGQVLSYAALNRRANRLAHRLIA 3129
+LH WNATAAD+P +H LIEAQV TPDA AL+FA + LSYA LN RAN+LAHRL
Sbjct: 1985 ILHDWNATAADFPSEDCLHSLIEAQVRATPDASALIFAAEQLSYAQLNARANQLAHRLRE 2044
Query: 3130 AGVGPDVLVGLAVERSIEMVVGLLAVLKAGGAYVPLDPEYPRDRLAYMLQDSDVKLLLTQ 3189
+GVGPDVLVG+ VERS+E+V+GLLA++KAGGAYVPLDP+YP DRLAYM+QDS + LLLTQ
Sbjct: 2045 SGVGPDVLVGICVERSLELVIGLLAIIKAGGAYVPLDPDYPEDRLAYMMQDSGIGLLLTQ 2104
Query: 3190 AHLLEQLPIPTGLHSLVLEQGDEWLQAYAEQNPLVTVDGENLAYVIYTSGSTGQPKGAGN 3249
LLE+LP+P L SL L+Q +WL+ Y+ NP+ NLAYVIYTSGSTG+PKGAGN
Sbjct: 2105 TALLERLPVPPQLQSLCLDQHGDWLEGYSTANPVNLSHPLNLAYVIYTSGSTGKPKGAGN 2164
Query: 3250 RHSALTNRLCWMQHAYGLEGSDTVLQKTPFSFDVSVWEFFWPLMTGARLVVAAPGDHRDP 3309
H AL NRL WMQ AY L+GSDTVLQKTPFSFDVSVWEFFWPLMTGARL VA PGDHRDP
Sbjct: 2165 SHRALVNRLHWMQKAYALDGSDTVLQKTPFSFDVSVWEFFWPLMTGARLAVALPGDHRDP 2224
Query: 3310 ARLVSLINAEHVTTLHFVPSMLQAFLQDAGVGACHSLQRIVCSGEALPVDAQQQVFAKLP 3369
RLV I VTTLHFVPSMLQAF+ V +C++L+R+VCSGEALP + QV +LP
Sbjct: 2225 ERLVQTIREHQVTTLHFVPSMLQAFMTHPQVESCNTLRRVVCSGEALPAELAAQVLKRLP 2284
Query: 3370 HAGLYNLYGPTEAAIDVTHWTCVDEGRDAVPIGRPIANLGCYVLDGNLEPAPVGVLGELY 3429
AGLYNLYGPTEAAIDVTHWTC + +VPIGRPI NL ++LD L PA GV ELY
Sbjct: 2285 LAGLYNLYGPTEAAIDVTHWTCSTDDILSVPIGRPIDNLKTHILDDGLLPAAQGVAAELY 2344
Query: 3430 LGGVGLARGYHRRPALTAERFVTDPFG--SGSRLYRTGDLARYRDDGVIEYAGRIDHQVK 3487
LGGVGLARGYH R ALTAERFV DPF G RLYRTGDLARYRD GVI+YAGRIDHQVK
Sbjct: 2345 LGGVGLARGYHNRAALTAERFVPDPFDEQGGGRLYRTGDLARYRDAGVIDYAGRIDHQVK 2404
Query: 3488 LRGLRIELGEIEARLLEHACVREAAVLAVD---GTHLVGYLV----LQAPSEDWKAQVAM 3540
+RGLRIELGEIEARL EHA VREA V+ +D G L YLV +AP + + ++
Sbjct: 2405 IRGLRIELGEIEARLHEHAAVREATVIDIDGPSGKQLAAYLVPTDATEAP-DVLRERLQA 2463
Query: 3541 HLAAQLPDYMVPAQWVVLTQMPLSPNGKLDRKALPKPE-AQGAGAYQAPQSAIEQQVAAI 3599
HL A +PDYMVP +V + MPL+ NGKLDR+ALPKP+ A+ Y AP+SA EQ++A +
Sbjct: 2464 HLKAHVPDYMVPGYFVFIDSMPLTANGKLDRRALPKPDVARSQQGYVAPRSAFEQRLAVL 2523
Query: 3600 WRDVLGVERVGLNDNFFELGGHSLLVLMLKERIRKVSGVGLSVSQLMLNPTVRGQVNCLQ 3659
W VL VERVGLNDNFF LGGHSLL + L RIR+ + + + L+L T+ + ++
Sbjct: 2524 WEQVLHVERVGLNDNFFALGGHSLLAVSLAGRIRETFDISIKLHDLLLLQTLGELADFMR 2583
Query: 3660 GD---ARSSLIVKLNSQTEGTPLFMFHPSFGSVHCYTAIALALREQRPVFGVICRALAEA 3716
D +S++I + + PLF P G + Y +A L + R V+G++ +A
Sbjct: 2584 ADEARVKSAVIAMNANSSTHAPLFCLPPGGGGTYSYYPLAGRLSDSRRVYGLVNKAYVVP 2643
Query: 3717 GAEVPEWQAMVEDYAEQLLLAQPQGAFRLAGWSLGGNLAMEVAYVLEQAGRDVEFVGWID 3776
G WQ MV+ Y EQ+ + QP G + L GWS+GG LA+EVA+VLE+AG V F+G +D
Sbjct: 2644 GWFDTSWQDMVDYYVEQIRMTQPHGPYNLLGWSMGGALAVEVAHVLERAGEVVSFLGLVD 2703
Query: 3777 SAPPQWLTPYWQAVVTEDDREISANER------------RAALLGVMFPAFAERIQAAWQ 3824
+ P + W E+D +++ ++ +A + G+ + I+ A Q
Sbjct: 2704 TQLPASVGMQW----VEEDPQVTTQQQGENYYRSLIKSLQAFVPGLQEQTIVDLIEKARQ 2759
Query: 3825 QCQRDAQDEAGQWQGFIAWAEQTLGEAFTGIKDELLRGNEAQISWEVDRALSERLSAADF 3884
++ + Q IA ++ + ++ +E + +++ A ++ A
Sbjct: 2760 SVSGES-EVIDQVIEQIALQHAMNVDSLRSMFQDIAVQDEIETGYKLLEANAKLSQAFTL 2818
Query: 3885 KPIKAPVSCWWASMSR-AGQFKDLIEQHMASTLVQGRIERSVVIETDHDGIIDSAEFIRS 3943
K + V CWWA SR GQ + V G + S I+ HD ++ + F++
Sbjct: 2819 KTLNVQVDCWWAGQSRKPGQIAKAEAVLLEQCSVNG-LRSSTTIDQRHDNLVIAEAFLQG 2877
Query: 3944 L 3944
L
Sbjct: 2878 L 2878
Score = 825 bits (2132), Expect = 0.0
Identities = 575/1557 (36%), Positives = 830/1557 (53%), Gaps = 87/1557 (5%)
Query: 9 LVSRFLRLPLEQRQQFYQRLQSRGMSFAQLPIASIREDGQMLPLSYAQERQWFLWQLDPD 68
+ RF+ LP+EQR+Q ++ G SF LPIA R ++PLSYAQ+R FLWQ++P
Sbjct: 16 IAQRFVGLPVEQRRQILAKMHETGQSFKLLPIAVTRHAAALIPLSYAQQRMLFLWQMEPG 75
Query: 69 SATYHIPGALRLQGRLDLAALQRAFDSLLARHESLRTRLVQDGERLLQNVAPEARIEIRQ 128
+A Y++P A+RL G LD AL A D L+ RHE+LRTR V + Q + +A++ +
Sbjct: 76 NAAYNVPMAVRLNGALDRQALSAALDRLVQRHETLRTRFVSEDGVFYQEILEQAKVALEF 135
Query: 129 DVADEQQLLARVEAEIARPFDLQAGPLLRVSLLQLAEDEHVLVMVQHHIISDGWSMQVMV 188
A ++ +V AE+ +PFDL +G LLRV L QL+E EHVL + HH++SDGWS +V++
Sbjct: 136 ASAAPAEIEQQVRAELQQPFDLLSGTLLRVKLFQLSESEHVLTVCMHHVVSDGWSGEVLI 195
Query: 189 EELVQFYAAHSQGREVQLPGLPIHYADYALWQRSWMEAGEKARQLAYWQDLLGGEQPVLE 248
E VQ Y A G+ LP L + YADYA+WQR+W+EAGE RQL YW+ LG E P+L
Sbjct: 196 REFVQLYQAQVSGQPAPLPELAVQYADYAIWQRAWLEAGEGERQLDYWKQQLGSEHPLLS 255
Query: 249 LPLDHPRPAQQSHCGASLQVHLPADLVAGIKRLAQQEGVTPFMLLLASFQTLLFRYSGQS 308
LPLDHPRP Q SH GA ++V LP L +K LA+ G T FM+ LA+ +L R+SGQS
Sbjct: 256 LPLDHPRPLQPSHRGAMVRVDLPQQLSVQLKSLARNNGQTLFMVTLAALSVVLSRFSGQS 315
Query: 309 DIRIGVPNANRNRVETERLIGFFVNTQVLKADLDGQMSFAELLQQAKRRSLEAQAHQDLP 368
DIRIG PNA R R E E LIGFF+NTQVL+ +D + SFAELL Q K+ AQ+HQ+LP
Sbjct: 316 DIRIGAPNAGRTRSELEGLIGFFINTQVLRVQVDERQSFAELLDQVKQVVTGAQSHQELP 375
Query: 369 FEQLVVALQPERSLSHNPLFQVMFNHQTDAQGGRDGQQLPGLRVAQLDWENQTTHFDLSL 428
FE LV AL PER+ HNPLFQ N A GR GQ++ GL V + ++ FDL+
Sbjct: 376 FEHLVDALAPERNPGHNPLFQFKINQHVLAADGR-GQRVSGLTVDEFPMDSSDARFDLAF 434
Query: 429 DTHESAEGLWAALTYATDLFESATIERLAQHWQNLLQAAVSAPRSRLC----VLSMLDAP 484
D ++ +G+ TYATDLFE+ T+ER+A +++LQA VS RL +S+ A
Sbjct: 435 DFTDTPDGIRGYFTYATDLFEAQTVERIADALRSVLQALVSDTDRRLADHPHAISLPVAE 494
Query: 485 EQQRMLKDWNAPATVAAPHAVHQLFEAQAREHPARQALALDDQTLSYGELNRQANRLAHY 544
+ Q D+ P ++ L++ R + AL + Q LS+ EL ++NR A Y
Sbjct: 495 QSQ----DFACPDFLS-------LWQQGLRAGRGKTALRVGQQVLSFDELETRSNRFARY 543
Query: 545 LIAQGVGPEVLVGIAVERSFAMVVSLLAVLKAGGAYVPLDPEYPRERLVHMLDDSGVRLV 604
L AQ + P + V + ++RS VVSLLAVLK G Y+PLD P ERL + DSG L+
Sbjct: 544 LHAQDIKPGMTVALCLDRSVEWVVSLLAVLKLGAVYLPLDSAQPAERLQQLARDSGAVLL 603
Query: 605 LTQSHLRDRLPLPADLTALDIDLADAQLAQCAEHNP-PTAFEPRSLAYVIYTSGSTGKPK 663
+ + RD A L + DA L + P AY+IYTSGSTG+PK
Sbjct: 604 V---YARDD-DKAARLGVCPVLAFDAALWAAVDSQALDVRVLPGQAAYIIYTSGSTGQPK 659
Query: 664 GVAISHAALSEFAGIAAEYSRLVADDRVLQFATLNFDGFVEQLYPALTLG-ATVVLRGPQ 722
GV ISH AL+ + E L + +T+ D L+ AL G A +L Q
Sbjct: 660 GVVISHGALANYVQGVLERLALSDGASMAMVSTVAADLGHTLLFGALASGRALHLLSHEQ 719
Query: 723 LWDGADLYRQIIDQGITLADLPTAYWKLFLQDCLAAGPRPYGALRQVHIGGEAMPLDGPV 782
+D R + + + + + ++ + LQ AA P + + +GGEA V
Sbjct: 720 AFDPDGFARYMAEHQVDVLKIVPSHLQGLLQ---AANPADVLPGQVLILGGEASAW-ALV 775
Query: 783 LWRRAGLGHVRLLNTYGPTEATVVSSVLDCSDDNAVMGATASPIGRALPGRGLYVLDPDL 842
RA R++N YGPTE TV +L + + P+G+ L VLD L
Sbjct: 776 EQVRALKPGCRVINHYGPTETTV--GILTHEVAGPLSACRSVPVGQPLANGKARVLDAYL 833
Query: 843 NLLPVGAVGELYIASAGGLARDYLQRPSLTAERFVADPFSTLGERLYRTGDLARYRADGV 902
N + GELY+ GLA+ YL R ++TAERFV DP + G+RLYR GD AR+ DGV
Sbjct: 834 NPVAERVAGELYLGGR-GLAQGYLGRAAMTAERFVPDPDAN-GQRLYRAGDRARW-VDGV 890
Query: 903 IEYVGRVDHQVKIRGFRIELGEIEALLLAQEAVREAFLLA----ADN---QLVAYLVPAQ 955
+EY+GR D QVKIRG+R+E GE+ LL E V +A +LA +D QLVAY V
Sbjct: 891 LEYLGRADDQVKIRGYRVEPGEVGQLLQTLENVADAVVLAQPLESDETRLQLVAYCV--- 947
Query: 956 PLSAAEQAAAGETLKATLREQLPDYMVPAHLIFLDRMPLNPNGKLDRQALPKPDGSAVQQ 1015
+AA + E+L+ L +LP+Y+VPA ++ L+R+P+ NGKLD++ALP P V+Q
Sbjct: 948 --AAAGASLNVESLRGQLAARLPEYLVPAQIMLLERLPVTANGKLDKRALPMP--GVVKQ 1003
Query: 1016 AWQAPVTPRQQQVAAIWADILGVERVGLTHHFFELGGHSLLAMQVVSRI-RQALKLEVPL 1074
+ APV ++++AA+WAD+L +E+VG T +FFELGG S+L++Q+++R RQ +KL
Sbjct: 1004 RYTAPVGEIEEKLAAVWADVLKLEQVGSTDNFFELGGDSILSLQIIARAKRQGIKLSP-- 1061
Query: 1075 KLLFEQPRLEGFVAALATQDPDAPTAPALLPVGRDQPLPLSYAQERQWFLWQLEPQSAAY 1134
K LFE+ + G +A++A P A A G LPL Q R + L E Q
Sbjct: 1062 KQLFEKQTI-GQLASVAKLIQKKPAAVAEQISG---SLPLLPIQARFFELDIPERQ---- 1113
Query: 1135 HIPSALRLK--GQLDLGALQRSFDTLLARHESLRT-HLRQERDRTVQIISPQVSLQIAHA 1191
H AL LK L+ LQ + L+ +H++LR RQ +P +
Sbjct: 1114 HWNQALMLKPLQTLEAAHLQSALTALVEQHDALRLGFTRQSGQWQATFGAPNTRELLWAH 1173
Query: 1192 EVHEAQLKARVEAEIAQPFNLEQGPLLRVSLLRIAADEHVLVLVQHHIVSDGWSMQLMVE 1251
E+ + + AE + +L+ GPLLR L+ + E L+LV HH+V DG S ++++E
Sbjct: 1174 ELDSIERLPELAAEAQRSLDLKNGPLLRAVLINLPQGEQRLLLVIHHLVVDGVSWRVLLE 1233
Query: 1252 ELVQLYAAYSQGQVLQWPALPIQYADYAVWQRNWMEAGEKARQLAYWRDMLGGEQSVLAL 1311
+L Q Y A + GQ PA +A + + + ++L YW+ L AL
Sbjct: 1234 DLQQAYIALAAGQPALLPAKTSSLQAWAEHLQAYAHSPALEQELGYWQTQLQDVSD--AL 1291
Query: 1312 PFDHPRPAVQSHRGARLAFELPGALT-QGLKALAKQQDVTLFMLLLASFQTLLHRYSGQE 1370
P DHP Q + +L LT Q L+ + LLL + ++ R++ +
Sbjct: 1292 PCDHPHGGQQQQHALSVVTQLNSELTRQLLQDAPAAYRTQINDLLLTALSRVVSRWTARP 1351
Query: 1371 EIRVGVPIANR----NRSETERLIGFFVNTQVLKADLHGQ-----MSVEQLLQQARQRAL 1421
+ + R + + R +G+F N ++ M++++ L+ + +
Sbjct: 1352 HALIRLEGHGREDLFDALDLSRTVGWFSNVYPVRLTPQASLADSIMTIKEQLRAVPDKGV 1411
Query: 1422 DAQAHQDLPFEQLVEALQPERSLSHNPLFQVMFNHQTDVGQAQVQQQLPN-LSVEGLEWE 1480
A + L E + LQ PL ++FN+ +GQ P L +
Sbjct: 1412 GYGALRYLGRESARQTLQA------LPLGSIVFNY---LGQFDGSFDAPEALFTPSADSS 1462
Query: 1481 SKTAHFDLDLDIQESTEG------IWATLGYAQDLFEASTVQRMARHWQNLLQGMVA 1531
+ D L S G + + ++ +FE TV R+A + LQ ++A
Sbjct: 1463 GASQSADAPLAAPISINGQVYAGELRLSWTFSGAVFERETVHRLADEYAAELQQLIA 1519
Score = 560 bits (1442), Expect = e-162
Identities = 388/1054 (36%), Positives = 554/1054 (52%), Gaps = 47/1054 (4%)
Query: 36 AQLPIASIREDGQMLPLSYAQERQWFLWQLDPDSATYHIPGALRLQGRLDLAALQRAFDS 95
++LPIA+ + + + PL+ Q+ F + +S Y + + G LD+ + A+ +
Sbjct: 1545 SRLPIAAGQIE-DLYPLAPMQQGMLFHTLFEQESGNYINQMRIEVSG-LDVPRFRAAWQA 1602
Query: 96 LLARHESLRTRLVQDGERLLQNVAPEAR---IEIRQDVADEQQLLARVEAEIARPFDLQA 152
L HE LR+ + + LQ V + R +E+ + +A+ + FDL
Sbjct: 1603 TLDAHEVLRSAFISHLQPALQVVLRDVRMPFVELDARGQSSDWIDQWADADRQQGFDLAQ 1662
Query: 153 GPLLRVSLLQLAEDEHVLVMVQHHIISDGWSMQVMVEELVQFYAAHSQGREVQLPGLPIH 212
GPLLR+++++ E H L+ HHI+ DGWS ++ E++Q Y+ + R+V
Sbjct: 1663 GPLLRLAVVRTGEQSHQLIYTSHHILMDGWSSSRLLGEVLQRYSGQTLPRQVS------R 1716
Query: 213 YADYALWQRSWMEAGEKARQLAYWQDLLGGEQPVLELPLDHPRPAQQSHCGASLQVHLPA 272
Y DY W + +AG R +W L L P G L + + A
Sbjct: 1717 YRDYIEWLQR-QDAGLSER---FWTGQLARLDEPTRLVQAFKAPDSGQGHGDYLHL-IDA 1771
Query: 273 DLVAGIKRLAQQEGVTPFMLLLASFQTLLFRYSGQSDIRIGVPNANR--NRVETERLIGF 330
+ + A+++ VT L+ +++ +L RY+GQS + G A R + E +G
Sbjct: 1772 ENTRQLSEFAREQRVTLNTLVQSAWLLVLQRYTGQSSVTFGATVAGRPADLPGVEEQLGL 1831
Query: 331 FVNTQVLKADLDGQMSFAELLQQAKRRSLEAQAHQDLPFEQLVVALQPERSLSHNPLFQV 390
F+NT + A + AE +QQ + +++ + H+ P ++ + RS +
Sbjct: 1832 FINTLPVIASPRAEQRVAEWVQQVQAQNIALREHEHTPLYEIQ---RWARSAGEALFDTI 1888
Query: 391 MFNHQTDAQGGRDGQQLPGLRVAQLDWENQTTHFDLSLDTHESAEGLWAALTYATDLFES 450
+ PGL L + QT H+ L+L + E L +YA + F
Sbjct: 1889 LVFENYPVSEALQQAAPPGLVFGGLHTQEQT-HYPLTLVVN-LGETLSLRFSYAREAFSE 1946
Query: 451 ATIERLAQHWQNLLQAAVSAPRSRLCVLSMLDAPEQQRMLKDWNAPAT-VAAPHAVHQLF 509
+ +L+ H+Q +LQA ++ L L++L+ EQQ++L DWNA A + +H L
Sbjct: 1947 QHMAQLSAHFQQVLQALTHDAQAALGELALLNDNEQQQILHDWNATAADFPSEDCLHSLI 2006
Query: 510 EAQAREHPARQALALDDQTLSYGELNRQANRLAHYLIAQGVGPEVLVGIAVERSFAMVVS 569
EAQ R P AL + LSY +LN +AN+LAH L GVGP+VLVGI VERS +V+
Sbjct: 2007 EAQVRATPDASALIFAAEQLSYAQLNARANQLAHRLRESGVGPDVLVGICVERSLELVIG 2066
Query: 570 LLAVLKAGGAYVPLDPEYPRERLVHMLDDSGVRLVLTQSHLRDRLPLPADLTALDIDLAD 629
LLA++KAGGAYVPLDP+YP +RL +M+ DSG+ L+LTQ+ L +RLP+P L +L +D
Sbjct: 2067 LLAIIKAGGAYVPLDPDYPEDRLAYMMQDSGIGLLLTQTALLERLPVPPQLQSLCLDQHG 2126
Query: 630 AQLAQCAEHNPPTAFEPRSLAYVIYTSGSTGKPKGVAISHAALSEFAGIAAEYSRLVADD 689
L + NP P +LAYVIYTSGSTGKPKG SH AL + L D
Sbjct: 2127 DWLEGYSTANPVNLSHPLNLAYVIYTSGSTGKPKGAGNSHRALVNRLHWMQKAYALDGSD 2186
Query: 690 RVLQFATLNFDGFVEQLYPALTLGATVVLRGPQLWDGADLYRQIIDQGITLADLPTAYWK 749
VLQ +FD V + + L GA + + P D D R + Q I + T ++
Sbjct: 2187 TVLQKTPFSFDVSVWEFFWPLMTGARLAVALP--GDHRDPERLV--QTIREHQVTTLHFV 2242
Query: 750 LFLQDCLAAGPR--PYGALRQVHIGGEAMP--LDGPVLWRRAGLGHVRLLNTYGPTEATV 805
+ P+ LR+V GEA+P L VL R G L N YGPTEA +
Sbjct: 2243 PSMLQAFMTHPQVESCNTLRRVVCSGEALPAELAAQVLKRLPLAG---LYNLYGPTEAAI 2299
Query: 806 VSSVLDCSDDNAVMGATASPIGRALPGRGLYVLDPDLNLLPVGAVGELYIASAGGLARDY 865
+ CS D+ + + PIGR + ++LD L G ELY+ GLAR Y
Sbjct: 2300 DVTHWTCSTDDIL----SVPIGRPIDNLKTHILDDGLLPAAQGVAAELYLGGV-GLARGY 2354
Query: 866 LQRPSLTAERFVADPFSTL-GERLYRTGDLARYRADGVIEYVGRVDHQVKIRGFRIELGE 924
R +LTAERFV DPF G RLYRTGDLARYR GVI+Y GR+DHQVKIRG RIELGE
Sbjct: 2355 HNRAALTAERFVPDPFDEQGGGRLYRTGDLARYRDAGVIDYAGRIDHQVKIRGLRIELGE 2414
Query: 925 IEALLLAQEAVREAFLLAAD----NQLVAYLVPAQPLSAAEQAAAGETLKATLREQLPDY 980
IEA L AVREA ++ D QL AYLVP A + E L+A L+ +PDY
Sbjct: 2415 IEARLHEHAAVREATVIDIDGPSGKQLAAYLVPTDATEAPD--VLRERLQAHLKAHVPDY 2472
Query: 981 MVPAHLIFLDRMPLNPNGKLDRQALPKPDGSAVQQAWQAPVTPRQQQVAAIWADILGVER 1040
MVP + +F+D MPL NGKLDR+ALPKPD + QQ + AP + +Q++A +W +L VER
Sbjct: 2473 MVPGYFVFIDSMPLTANGKLDRRALPKPDVARSQQGYVAPRSAFEQRLAVLWEQVLHVER 2532
Query: 1041 VGLTHHFFELGGHSLLAMQVVSRIRQALKLEVPL 1074
VGL +FF LGGHSLLA+ + RIR+ + + L
Sbjct: 2533 VGLNDNFFALGGHSLLAVSLAGRIRETFDISIKL 2566