Pairwise Alignments
Query, 3949 a.a., peptide synthase from Pseudomonas simiae WCS417
Subject, 4775 a.a., non-ribosomal peptide synthase domain TIGR01720/amino acid adenylation domain-containing protein from Paraburkholderia bryophila 376MFSha3.1
Score = 1337 bits (3461), Expect = 0.0
Identities = 949/2696 (35%), Positives = 1377/2696 (51%), Gaps = 217/2696 (8%)
Query: 50 LPLSYAQERQWFLWQLDPDSATYHIPGALRLQGRLDLAALQRAFDSLLARHESLRTRLVQ 109
+PLS +Q+ WFLW+LDP S YH+ GALR G+LD+ AL+ AF SL RH +LR R +
Sbjct: 1840 MPLSPSQQSLWFLWKLDPHSVAYHVNGALRFDGQLDVDALRAAFVSLGKRHPALRMRFAE 1899
Query: 110 DGERLLQNVAPEARIEIR-------QDVADEQQLLARVEAEIARPFDLQAGPLLRVSLLQ 162
Q + R EIR + E+ L A + A + PFDL A P +R +L++
Sbjct: 1900 IEGVPYQRIDDTCRSEIRLLDLPNTHNDTSEEALAACLGALVRTPFDLSAEPPVRATLVR 1959
Query: 163 LAEDEHVLVMVQHHIISDGWSMQVMVEELVQFYAAH-SQGREVQLPGLP----------- 210
+A+D HVL +V HHI+SD WS+ ++ + + Y + + G + +
Sbjct: 1960 MADDCHVLHLVLHHIVSDDWSLGLLFADFSRLYRDYCAAGPAASVTSVASIADDERIAAT 2019
Query: 211 --IHYADYALWQRSWMEAGEKARQLAYWQDLLGGEQP---VLELPLDHPRPAQQSHCGAS 265
Y + + + + + +QLA+W+ L + L LP D R + GA
Sbjct: 2020 SAAAYRELISARAARLTPERELQQLAWWRAALTNDDESPATLALPYDRTRSGSRCAPGAR 2079
Query: 266 LQVHLPADLVAGIKRLAQQEGVTPFMLLLASFQTLLFRYSGQSDIRIGVPNANRNRVETE 325
+V +PA ++ LA T FM LLA+ LL+RYSGQSDIR+GVP A R+
Sbjct: 2080 HRVRVPAGTAHALRALASARRATLFMTLLAAVDALLYRYSGQSDIRLGVPLAGRDLPGAA 2139
Query: 326 RLIGFFVNTQVLKADLDGQMSFAELLQQAKRRSLEAQAHQDLPFEQLVVALQPERSLSHN 385
+ GFFVNT V++ G+ A+L+ + R L A A+QD+PF +V A+QPER L+
Sbjct: 2140 DVAGFFVNTVVIRTTPRGETRAAQLIDDVRERLLGAYANQDVPFASVVKAVQPERDLAQT 2199
Query: 386 PLFQVMFN----HQTDAQGGRDGQQLPGLRVAQLDWENQTTHFDLSLDTHESAEG-LWAA 440
PLFQV+ N H A G GLRV + +N FDL L+ E+A+G + A
Sbjct: 2200 PLFQVLVNQQQRHDLAASFGE------GLRVTVQEVDNGEAQFDLMLNIAEAADGAIDLA 2253
Query: 441 LTYATDLFESATIERLAQHWQNLLQAAVSAPRSRLCVLSMLDAPEQQRMLKDWNAPATVA 500
TYATD+F+++TIERLA+++ LL +AP +R+ + + +Q P+T A
Sbjct: 2254 FTYATDVFDASTIERLARNFTGLLDQWSAAPDARIASFELPELGDQPSP----RLPSTFA 2309
Query: 501 APHAVHQLFEAQAREHPARQALALDDQTLSYGELNRQANRLAHYLIAQGVGPEVLVGIAV 560
++ AQAR P AL D+ ++Y +L+ + +AH L G E VG+A+
Sbjct: 2310 YEPVTTRI-AAQARARPEAVALVDGDEHVTYAQLDVWSRAIAHELRRLGATAETRVGVAM 2368
Query: 561 ERSFAMVVSLLAVLKAGGAYVPLDPEYPRERLVHMLDDSGVRLVLTQ-SHLRDRLPLPAD 619
+RS A+V SLL VL+AG AYVPLDP YP RL H+LDDS +RL++T S L L
Sbjct: 2369 QRSAALVASLLGVLRAGAAYVPLDPSYPVGRLTHILDDSQLRLIVTDASSLAQHASLFGS 2428
Query: 620 LTALD-IDLADAQLAQCAEHNPPTAFEPRSLAYVIYTSGSTGKPKGVAISHAALSEFAGI 678
+D + L DA A + + P+ LAYVIYTSGSTG PKGV ++H ++
Sbjct: 2429 RPTVDAVALRDAVPADATD-DAGAYPHPQQLAYVIYTSGSTGVPKGVGVTHENVARLFDA 2487
Query: 679 AAEYSRLVADDRVLQFATLNFDGFVEQLYPALTLGATVVL------RGPQLWDGADLYRQ 732
A D F + FD V +++ AL GA +V+ R P + L R+
Sbjct: 2488 TQSRFAFDAQDVWTLFHSYAFDFSVWEMFGALVHGARLVIVPHWSAREPAAFHA--LLRK 2545
Query: 733 IIDQGITLADLPTAYWKLFLQDCLAAGPRPYGALRQVHIGGEAMPLDGPVLW----RRAG 788
+Q L P+A+ +L D +LR V GGE + W RR G
Sbjct: 2546 --EQVTVLNQTPSAFVQLIQTD----DGNTLDSLRAVIFGGERLEPSLLARWAEGARRKG 2599
Query: 789 LGHVRLLNTYGPTEATVVSSVLDCSDDNAVMGATASPIGRALPGRGLYVLDPDLNLLPVG 848
L+N YG TE TV V + D A + S IG L L+VLD DLN +P+G
Sbjct: 2600 TLPA-LVNMYGITETTV--HVTHRTLDEAALRDGRSVIGAPLDDLTLHVLDADLNRVPLG 2656
Query: 849 AVGELYIASAGGLARDYLQRPSLTAERFVADPFSTLGERLYRTGDLARYRADGVIEYVGR 908
AVGELY+ AG LAR YL R +L+A+RFV DP+ G RLYR+GDLAR DG +EY+GR
Sbjct: 2657 AVGELYVGGAG-LARGYLGRAALSAQRFVPDPYGAPGARLYRSGDLARRLPDGDLEYLGR 2715
Query: 909 VDHQVKIRGFRIELGEIEALLLAQEAVREAFLLAA------------DNQLVAYLVPAQP 956
D QVKIRGFRIELGEI+A L A VR+ +LA+ + +L+AY+VP
Sbjct: 2716 NDDQVKIRGFRIELGEIQAALRAHPEVRDVAVLASGHGNGNGNNANDNRRLIAYVVPRGG 2775
Query: 957 LSAAEQAAAGETLKATLREQLPDYMVPAHLIFLDRMPLNPNGKLDRQALPKPDGSAVQQA 1016
+A + AG + L +LP +MVP+ + L+R PL PNGKLDR+ALP P+ A +
Sbjct: 2776 PNAGD---AGRW-QTWLAARLPGHMVPSSYVELERFPLTPNGKLDRRALPAPEAVANAKQ 2831
Query: 1017 WQAPVTPRQQQVAAIWADILGVERVGLTHHFFELGGHSLLAMQVVSRIRQALKLEVPLKL 1076
A TP + + A+W +L + +G+T +FF +GG S+L++Q+V++ R A L V ++
Sbjct: 2832 GVAASTPAEAALLAVWRAVLRRDDIGVTDNFFVIGGDSILSLQIVAKARDA-GLHVTPRM 2890
Query: 1077 LFEQPRLEGFV-----------AALATQDPDAPTAPA----------LLPVGRDQPLPLS 1115
+FE P ++ A+LA +P A T+ + + P + P +
Sbjct: 2891 VFEAPTVQQLARAAGPVPASASASLAGVEPSAVTSASASSDLWRALGITPEHVEDVYPAT 2950
Query: 1116 YAQERQWFLWQLEPQSAAYHIPSALRLKGQLDLGALQRSFDTLLARHESLRTHLRQERDR 1175
Q + E Q AY L G LD+ A+ ++ LARH LRT +
Sbjct: 2951 PLQSGLLYHTLAESQQGAYLNQMRATLSGTLDVAAMHAAWQAALARHAILRTGFAWQHGG 3010
Query: 1176 TV-QIISPQVSLQI-----AHAEVHEAQLKARVEAEIAQPFNLEQGPLLRVSLLRIAADE 1229
+V QI+ ++L + A ++A+L ++A ++ PL+R++L A
Sbjct: 3011 SVMQIVHRSIALPFETHDWSAAPDYDARLADWRARDLADGIAPDEAPLMRIALFIRDAHT 3070
Query: 1230 HVLVLVQHHIVSDGWSMQLMVEELVQLYAAYSQGQVLQWPALPIQYADYAVWQRNWMEAG 1289
LV HH++ DGWS+ L+ E+++ Y + G + P Y Y W R EA
Sbjct: 3071 ADLVWTHHHLLLDGWSVSLLFAEILRDYRLRTSGAAATFEQAP-PYRGYVEWIR---EAA 3126
Query: 1290 EKARQLAYWRDMLG--GEQSVLALPFDHPRPAVQSHRGARLAFELPGALTQGLKALAKQQ 1347
+ A+WR + + L PR A R A L AL L A A++
Sbjct: 3127 DDPATEAWWRAWAARADDPATLTASLGEPRAAEPGAHARRCA--LDEALVARLHATARRH 3184
Query: 1348 DVTLFMLLLASFQTLLHRYSGQEEIRVGVPIANR--NRSETERLIGFFVNTQVLKADLHG 1405
++TL L+ ++ LL RY + ++ G ++ R + ER++G F+NT ++ D+
Sbjct: 3185 EITLNTLMQGAWAVLLARYGHRRQVSYGTTLSGRPAHLPGVERMLGLFINTLPVQVDVDA 3244
Query: 1406 QMSVEQLLQQARQRALDAQAHQDLPFEQLVEALQPERSLSHNPLFQ---VMFNHQTDVGQ 1462
+ L + + ++ + ++ P ++ Q S + LF V N+ D +
Sbjct: 3245 SADLGAWLHKLQGELMELRHYEHTPLARV----QQWSGRSGDALFDSIVVFENYPVDAAR 3300
Query: 1463 AQVQQQLPNLSVEGLEWESKTAHFDLDLDIQESTEGIWATLGYAQDLFEASTVQRMARHW 1522
+L VE ++ T H+ L L I + + + + + TV+R+A +
Sbjct: 3301 ----DGDASLKVESIDSVDPT-HYPLALAIIPRGKTLSLEWAWNGERIDRETVERIALQY 3355
Query: 1523 QNLLQGMVADPRQTLSQLNLLDNTERQQILQRWDQSDAGFSAKRLVHELVADRAGETPEA 1582
+ +L M D + + L L E LQR+ G + +A +A +P+A
Sbjct: 3356 EAILDQMTDDVARRVGSLTLPGRYEAAP-LQRYAFESLGMA--------LAAQAKRSPDA 3406
Query: 1583 VAVKFGEQQLTYGELDRQANRLAHALIARGVGPEVRVAIAMPRSAEIMVAFLAVMKAGGV 1642
+A++ ++ LTY ELD + LA L+ARGVG E RV + + R ++ A L ++++GG
Sbjct: 3407 IALRCEDESLTYAELDAWSAMLAARLVARGVGAERRVGLCVARGPALVAALLGIIRSGGA 3466
Query: 1643 YVPLDIEYPRDRLLYMMQDSR-ARLLLTHSTVQQRLPIPDGLEALAVDQTQ---AWSAND 1698
+VPLD EYP RL M+ D+ ++ ++ +Q + G E + V TQ SA
Sbjct: 3467 FVPLDPEYPPARLAQMIDDAGIVEVVADSASAKQVAAVLAGCEVVEVRTTQHDAVLSAET 3526
Query: 1699 DSAP-----EVVLDGDNLAYVIYTSGSTGMPKGVAVSHGPLVAHIIATGERYETSPADCE 1753
+A + L D LAYV+YTSGSTG PKGV VSHG L H+ Y D
Sbjct: 3527 ATAAAPHFLDAPLHPDQLAYVLYTSGSTGRPKGVGVSHGALWTHLQDFLATYGIDGTDTV 3586
Query: 1754 LHFMSFAFDGSHEGWMHPLINGASVLIRDDSLWLPEYTYQQMHRHHVTMAVFPPVYLQQL 1813
LH + FD + + L+ GA+V +R W + +++ + VT A P QQ
Sbjct: 3587 LHSSTINFDVALHETLPALLRGATVEMRGTQPWDLQSLSERLVKRRVTFARIPTALWQQW 3646
Query: 1814 AEHAERDGNPPK----VRVYCFGGDAVAQASYDLAWRA--LKPTYLFNGYGPTETVVTPL 1867
HA PP+ +R GG+A+ + WR L L N YGPTET V L
Sbjct: 3647 QRHA-----PPRAQLALRQVTVGGEALPGDAL-ARWREGPLADIRLDNLYGPTETTVAAL 3700
Query: 1868 LWKARKGDPCGAVYAPIGTLLGNRSGYVLDAQLNLQPIGVAGELYLGGEGVARGYLERPA 1927
++ D V PIG R+ V DA + P+G GEL +GG VARGY R A
Sbjct: 3701 -YRRTGADDARQVTVPIGHPYPGRTARVFDAFGDEAPVGGLGELCIGGPTVARGYQGRAA 3759
Query: 1928 LTAERFVPDPFGKPGSRVYRSGDLTRGRPDGGVDYLGRVDHQVKIRGFRIELGEIEARLR 1987
LTAERFVPDP+G+PG+RVYRSGDL R R DG ++LGR+D QVK+RG RIELGEIEA LR
Sbjct: 3760 LTAERFVPDPYGEPGARVYRSGDLCRVRADGTAEFLGRLDQQVKLRGQRIELGEIEAVLR 3819
Query: 1988 EQDSVGETVVVAQEGPSGKQ-LVAYVVPLDPLLIDDAVAQSTCREALRRALKARLPDYMV 2046
+ + V E V+ GP+ KQ L AYV D A + + L+R L+ +LP YMV
Sbjct: 3820 QCEGVREAAVIV-VGPAQKQRLAAYVAGQS----DAASLPTVDAQRLQRELERKLPGYMV 3874
Query: 2047 PTHLMFLERMPLTPNGKLDRKGLPRPDVSQMQQVYVAPQSELEQKIAAIWSDVLRLPRVG 2106
P+ + L R+P PNGKLDR LP P +++ VAP +E+E + +IW+ VL +G
Sbjct: 3875 PSSITVLARLPWMPNGKLDRASLPAPQAGAIER--VAPSNEVEAALLSIWAAVLGRDDLG 3932
Query: 2107 LHDNFFELGGDSIISIQVVSRARQAGVRFTPKDLFQHQTVQSLAAVAREGEGAVV--LDQ 2164
+ DNFFE GGDSI S+Q+++RAR+AG R TP+ +F+H TV LA A+ E V +D
Sbjct: 3933 VTDNFFEAGGDSIQSLQIIARAREAGWRLTPRQVFEHPTVAGLAQRAQRLEAGAVQEIDD 3992
Query: 2165 SALTGDLLLLPVQQAFFADDIPRRHHWNQSVVLQPHQALQAPLLVAALQALIVHHDALRI 2224
A L L P+Q+ FF HWNQ+V+L+ L L A+ AL HDALR+
Sbjct: 3993 GAA---LPLTPIQRLFFERYPQGESHWNQAVLLKVKGRLVPAALERAVAALEARHDALRL 4049
Query: 2225 GFVQGAAGW----------SAAYRGPQQHQAEQ--------------------------- 2247
FV+ A W S A R P Q
Sbjct: 4050 RFVKEAGEWKQVAVKAAGTSEAERAPNASQVSNASDASEEAQASRTSEPLQTSQPSQSAS 4109
Query: 2248 --VLWQTTLNAVEELEALGEEAQRSLDLSEGPLLRAVLVDLADGSQRLLLVIHHLVVDGV 2305
V+ L ++ L A + Q SL++ GP+ R + D R+L+ IHHL VDGV
Sbjct: 4110 TTVVHHDHLTSLAGLTAACDRIQSSLNIEHGPVWRIGHFETPD-ETRVLIAIHHLAVDGV 4168
Query: 2306 SWRILLEDLQTAYRQVAQGAKVVLPAKTSAIRAWAERLQAYARSAALAQELAWWQTQLQG 2365
SWR+LLE+LQTAY Q + + LPA + + RAW + YA S+ ELAWWQT L
Sbjct: 4169 SWRVLLEELQTAYEQAERDEPIALPAPSMSWRAWVRAINQYAESSERVSELAWWQTSLDA 4228
Query: 2366 SPTGLPGADPQASLSNRHALSVTTHLDQVFTRRLLQDAPSAYRTQINDLLLTALARVVVR 2425
P S + ++ L T LL++AP AY+ +++++LL AL R +
Sbjct: 4229 PALRAGPLFPPLSSHPQPQKTLLKKLSPDMTAELLREAPRAYKMRVDEVLLAALVRAIGD 4288
Query: 2426 WTGDASMLIRLEGHGREDLFDEIDLTRTVGWFTSLYPVKLVPTDSLAGSLKQIKEQLRAI 2485
+L+ LEGHGRED+ + DL+RTVGWFT+ YP+ L A SL +++E+L A+
Sbjct: 4289 TVARDEVLVELEGHGREDVIEGADLSRTVGWFTTQYPLALPRGVDSADSLLRVRERLAAV 4348
Query: 2486 PDKGLGFGALRYLGNAEAQQALSELPRPRITFNYLGQFDGSFDGGEQEGLFVPSGDGSGA 2545
P +GLG+G L +A +Q AL LP P I FNYLG+FD +FDG + G F P G
Sbjct: 4349 PLRGLGWGLLACCADAASQSALRALPSPEIGFNYLGRFDQTFDGESRFG-FAPESSGDAI 4407
Query: 2546 EQSGEAPLGNWLEINGQVYAGELKLNWSFSQQMFDEATVQRLADDYAAELKALIEH 2601
P L+ING + L NW ++ Q + + L + + L L+ H
Sbjct: 4408 APHARIP-DRALDINGWIAGNSLTFNWGYAPQFLSDELAEELFASFESALGELLAH 4462
Score = 1048 bits (2711), Expect = 0.0
Identities = 917/2789 (32%), Positives = 1319/2789 (47%), Gaps = 316/2789 (11%)
Query: 51 PLSYAQERQWFLWQLDPDSATYHIPGALRLQGRLDLAALQRAFDSLLARHESLRTRLVQD 110
P + Q+ F LD + Y L + L + ++ A+D+++ARH LRTR V
Sbjct: 717 PATPMQQGLLFHGMLDGEPGMYVSQLRLTIDS-LKIDTMRAAWDAVIARHPVLRTRFVWP 775
Query: 111 -GERLLQNVAPEARIEIRQDVAD-----------------EQQLLARVEAE----IARPF 148
G LQ V R+ D E+Q A EA R F
Sbjct: 776 AGGEPLQIVERRVRMPFELHPRDALVVPVPIAALTAAASTEEQYDAAYEAARDAIATRGF 835
Query: 149 DLQAGPLLRVSLLQLAEDEHVLVMVQHHIISDGWSMQVMVEELVQFYAAHSQGREVQL-P 207
+ PL+RV + + + H L+ HH ++DGWS +V E+ + YAA G P
Sbjct: 836 EPDVAPLMRVDVFERPDGAHDLLWTHHHALTDGWSTAQVVSEVARAYAALDAGGVPDTSP 895
Query: 208 GLPIHYADYALWQRS-------WMEAGEKARQLAYWQDLLGGEQPVLELPLDHPRPAQQS 260
P YADY W R W + A D LGG +++S
Sbjct: 896 AAP--YADYVHWLRGQPDTAPFWRARLATRDEPARVADALGGALRA---------SSEKS 944
Query: 261 HCGASLQV---HLPADLVAGIKRLAQQEGVTPFMLLLASFQTLLFRYSGQSDIRIGVPNA 317
G + Q L A + R A++ VT L+ A++ L R+SG++ + G+ +
Sbjct: 945 ADGVAAQALIRELDGPSHARLTRAARRAQVTLNTLVQAAWALALARFSGRTQVTFGMTVS 1004
Query: 318 NR--NRVETERLIGFFVNTQVLKADLDGQMSFAELLQQAKRRSLEAQAHQDLPFEQLVVA 375
R + + ++G F+N+ L D+ + L +R++ E + + P + +
Sbjct: 1005 GRPVDLPNAQSIVGLFINSLPLWVDVKSDATVRSWLAALQRQNAELRDVEHTP----LAS 1060
Query: 376 LQPERSLSHNPLFQ---VMFNHQTDAQGGRDGQQLPGLRVAQLDWENQTTHFDLSLDTHE 432
LQ + + + LF V N+ D G +P R+ +D N++ HF L L
Sbjct: 1061 LQQWANSNVDALFDSLIVFENYPLDDALDALGD-VP--RIRAVDAHNRS-HFPLMLVVAP 1116
Query: 433 SAEGLWAALT-----YATDLFESATIERLAQHWQNLLQAAVSA------PRSRLCVLSML 481
G AL +A + E + R+A++++ +L +A P RL L
Sbjct: 1117 RHVGGGDALRLEWHRHAATVSEEG-VARIAKYFERMLDCLATALVEGDDPHVRLRDLPTD 1175
Query: 482 DAPEQQRMLKDWNAPATVAAPHAVHQLFEAQAREHPARQALALDDQTLSYGELNRQANRL 541
DAP K P+T A ++ AQAR P AL D+ ++Y +L+ + +
Sbjct: 1176 DAPSA----KSPRLPSTFAYEPVTARI-AAQARARPEAIALIDGDEHVTYAQLDVWSRAI 1230
Query: 542 AHYLIAQGVGPEVLVGIAVERSFAMVVSLLAVLKAGGAYVPLDPEYPRERLVHMLDDSGV 601
A L G E VG+A++R A+V SLL VL+AG AYVPLDP YP RL H++DD+ +
Sbjct: 1231 ADELRRLGATAETRVGVAMQRGAALVASLLGVLRAGAAYVPLDPSYPVGRLAHIVDDAQL 1290
Query: 602 RLVLTQ-SHLRDRLPLPADLTALD-IDLADAQLAQCAEHNPPTAF---EPRSLAYVIYTS 656
RL++T S L L +D + L DA A + A P+ LAYVIYTS
Sbjct: 1291 RLIVTDASSLAQHASLFGSRPTVDAVALRDAVPADATGDDTADAGAYPHPQQLAYVIYTS 1350
Query: 657 GSTGKPKGVAISHAALSEFAGIAAEYSRLVADDRVLQFATLNFDGFVEQLYPALTLGATV 716
GSTG PKGV ++H ++ A D F + FD V +++ AL GA +
Sbjct: 1351 GSTGVPKGVGVTHENVARLFDATQSRFAFDAQDVWTLFHSYAFDFSVWEIFGALVHGARL 1410
Query: 717 VLRGPQLWDG---ADLYRQIIDQGIT-LADLPTAYWKLFLQDCLAAGPRPYGALRQVHIG 772
V+ W A + + + +T L P+A+ +L D +LR V G
Sbjct: 1411 VI--VPHWSAREPAAFHALLRKERVTVLNQTPSAFVQLIQAD----DGNTLDSLRAVIFG 1464
Query: 773 GEAMPLDGPVLW----RRAGLGHVRLLNTYGPTEATVVSSVLDCSDDNAVMGATASPIGR 828
GE + W RR G+ L+N YG TE TV V + D A + S IG
Sbjct: 1465 GERLEPSSLARWAEGARRKGVLPA-LVNMYGITETTV--HVTHRTLDEAALRDGRSVIGA 1521
Query: 829 ALPGRGLYVLDPDLNLLPVGAVGELYIASAGGLARDYLQRPSLTAERFVADPFSTLGERL 888
L L+VLD DLN +P+GAVGELY+ AG LAR YL R +L+A+RFV DP+ G RL
Sbjct: 1522 PLDDLTLHVLDADLNRVPLGAVGELYVGGAG-LARGYLGRAALSAQRFVPDPYGAPGARL 1580
Query: 889 YRTGDLARYRADGVIEYVGRVDHQVKIRGFRIELGEIEALLLAQEAVREAFLL------- 941
Y +GDLAR DG +EY+GR D QVKIRGFRIELGEI+A L A VR+ +L
Sbjct: 1581 YSSGDLARRLPDGDLEYLGRNDDQVKIRGFRIELGEIQAALRAHPEVRDVAVLVSGHGNG 1640
Query: 942 --AADN-QLVAYLVPAQPLSAAEQAAAGETLKATLREQLPDYMVPAHLIFLDRMPLNPNG 998
A DN +L+AY+VP +A + AG + L +LP +MVP+ + L+R PL NG
Sbjct: 1641 NNANDNRRLIAYVVPRGGPNAGD---AGR-WQTWLAARLPGHMVPSSYVELERFPLTLNG 1696
Query: 999 KLDRQALPKPD-GSAVQQAWQAPVTPRQQQVAAIWADILGVERVGLTHHFFELGGHSLLA 1057
KLDR+ALP P+ ++ + + AP Q ++AAIW +LGVERVG FF LGGHSLLA
Sbjct: 1697 KLDRRALPAPEVANSSRATYVAPHGETQTKLAAIWQQVLGVERVGAHDDFFLLGGHSLLA 1756
Query: 1058 MQVVSRIRQALKLEVPLKLLFEQPRLEGFVAAL-----ATQDPDAPTAPALLPVGRD--- 1109
++V+S +R L+ +FE PRLE F L A D A T+ + + V D
Sbjct: 1757 VRVLSAVRTVFGDAPGLRAVFEHPRLEDFATLLSAAQSAGADDGALTSASGVAVAADGDA 1816
Query: 1110 ---------------------QPLPLSYAQERQWFLWQLEPQSAAYHIPSALRLKGQLDL 1148
P+PLS +Q+ WFLW+L+P S AYH+ ALR GQLD+
Sbjct: 1817 AALSVTAAVTAADVARQADVTAPMPLSPSQQSLWFLWKLDPHSVAYHVNGALRFDGQLDV 1876
Query: 1149 GALQRSFDTLLARHESLRTHLR-------QERDRTVQIISPQVSLQIAHAEVHEAQLKAR 1201
AL+ +F +L RH +LR Q D T + + L H + E L A
Sbjct: 1877 DALRAAFVSLGKRHPALRMRFAEIEGVPYQRIDDTCRSEIRLLDLPNTHNDTSEEALAAC 1936
Query: 1202 VEAEIAQPFNLEQGPLLRVSLLRIAADEHVLVLVQHHIVSDGWSMQLMVEELVQLYAAYS 1261
+ A + PF+L P +R +L+R+A D HVL LV HHIVSD WS+ L+ + +LY Y
Sbjct: 1937 LGALVRTPFDLSAEPPVRATLVRMADDCHVLHLVLHHIVSDDWSLGLLFADFSRLYRDYC 1996
Query: 1262 QGQVLQWPALPIQYAD-------YAVWQRNWMEA-------GEKARQLAYWRDMLGGEQ- 1306
AD A R + A + +QLA+WR L +
Sbjct: 1997 AAGPAASVTSVASIADDERIAATSAAAYRELISARAARLTPERELQQLAWWRAALTNDDE 2056
Query: 1307 --SVLALPFDHPRPAVQSHRGARLAFELPGALTQGLKALAKQQDVTLFMLLLASFQTLLH 1364
+ LALP+D R + GAR +P L+ALA + TLFM LLA+ LL+
Sbjct: 2057 SPATLALPYDRTRSGSRCAPGARHRVRVPAGTAHALRALASARRATLFMTLLAAVDALLY 2116
Query: 1365 RYSGQEEIRVGVPIANRNRSETERLIGFFVNTQVLKADLHGQMSVEQLLQQARQRALDAQ 1424
RYSGQ +IR+GVP+A R+ + GFFVNT V++ G+ QL+ R+R L A
Sbjct: 2117 RYSGQSDIRLGVPLAGRDLPGAADVAGFFVNTVVIRTTPRGETRAAQLIDDVRERLLGAY 2176
Query: 1425 AHQDLPFEQLVEALQPERSLSHNPLFQVMFNHQTDVGQAQVQQQLPNLSVEGLEWESKTA 1484
A+QD+PF +V+A+QPER L+ PLFQV+ N Q A + L V E ++ A
Sbjct: 2177 ANQDVPFASVVKAVQPERDLAQTPLFQVLVNQQQRHDLAASFGE--GLRVTVQEVDNGEA 2234
Query: 1485 HFDLDLDIQESTEG-IWATLGYAQDLFEASTVQRMARHWQNLLQGMVADPRQTLSQLNLL 1543
FDL L+I E+ +G I YA D+F+AST++R+AR++ LL A P ++ L
Sbjct: 2235 QFDLMLNIAEAADGAIDLAFTYATDVFDASTIERLARNFTGLLDQWSAAPDARIASFELP 2294
Query: 1544 DNTERQQILQRWDQSDAGFSAKRLVHELVADRAGETPEAVAVKFGEQQLTYGELDRQANR 1603
+ + Q + + F A V +A +A PEAVA+ G++ +TY +LD +
Sbjct: 2295 ELGD-----QPSPRLPSTF-AYEPVTTRIAAQARARPEAVALVDGDEHVTYAQLDVWSRA 2348
Query: 1604 LAHALIARGVGPEVRVAIAMPRSAEIMVAFLAVMKAGGVYVPLDIEYPRDRLLYMMQDSR 1663
+AH L G E RV +AM RSA ++ + L V++AG YVPLD YP RL +++ DS+
Sbjct: 2349 IAHELRRLGATAETRVGVAMQRSAALVASLLGVLRAGAAYVPLDPSYPVGRLTHILDDSQ 2408
Query: 1664 ARLLLTH-STVQQRLPI---PDGLEALAVDQTQAWSANDDSAPEVVLDGDNLAYVIYTSG 1719
RL++T S++ Q + ++A+A+ A DD+ LAYVIYTSG
Sbjct: 2409 LRLIVTDASSLAQHASLFGSRPTVDAVALRDAVPADATDDAG--AYPHPQQLAYVIYTSG 2466
Query: 1720 STGMPKGVAVSHGPLVAHIIATGERYETSPADCELHFMSFAFDGSHEGWMHPLINGAS-V 1778
STG+PKGV V+H + AT R+ D F S+AFD S L++GA V
Sbjct: 2467 STGVPKGVGVTHENVARLFDATQSRFAFDAQDVWTLFHSYAFDFSVWEMFGALVHGARLV 2526
Query: 1779 LIRDDSLWLPEYTYQQMHRHHVTMAVFPPVYLQQLAEHAERDGNP-PKVRVYCFGGDAVA 1837
++ S P + + + VT+ P QL + DGN +R FGG+ +
Sbjct: 2527 IVPHWSAREPAAFHALLRKEQVTVLNQTPSAFVQLIQ--TDDGNTLDSLRAVIFGGERL- 2583
Query: 1838 QASYDLAW-----RALKPTYLFNGYGPTET---VVTPLLWKARKGDPCGAVYAPIGTLLG 1889
+ S W R L N YG TET V L +A D + AP+ L
Sbjct: 2584 EPSLLARWAEGARRKGTLPALVNMYGITETTVHVTHRTLDEAALRDGRSVIGAPLDDL-- 2641
Query: 1890 NRSGYVLDAQLNLQPIGVAGELYLGGEGVARGYLERPALTAERFVPDPFGKPGSRVYRSG 1949
+ +VLDA LN P+G GELY+GG G+ARGYL R AL+A+RFVPDP+G PG+R+YRSG
Sbjct: 2642 --TLHVLDADLNRVPLGAVGELYVGGAGLARGYLGRAALSAQRFVPDPYGAPGARLYRSG 2699
Query: 1950 DLTRGRPDGGVDYLGRVDHQVKIRGFRIELGEIEARLREQDSVGETVVVAQEGPSG---- 2005
DL R PDG ++YLGR D QVKIRGFRIELGEI+A LR V + V+A +G
Sbjct: 2700 DLARRLPDGDLEYLGRNDDQVKIRGFRIELGEIQAALRAHPEVRDVAVLASGHGNGNGNN 2759
Query: 2006 ----KQLVAYVVPLDPLLIDDAVAQSTCREALRRALKARLPDYMVPTHLMFLERMPLTPN 2061
++L+AYVVP DA T L ARLP +MVP+ + LER PLTPN
Sbjct: 2760 ANDNRRLIAYVVPRGGPNAGDAGRWQTW-------LAARLPGHMVPSSYVELERFPLTPN 2812
Query: 2062 GKLDRKGLPRPDVSQMQQVYVAPQSELEQKIAAIWSDVLRLPRVGLHDNFFELGGDSIIS 2121
GKLDR+ LP P+ + VA + E + A+W VLR +G+ DNFF +GGDSI+S
Sbjct: 2813 GKLDRRALPAPEAVANAKQGVAASTPAEAALLAVWRAVLRRDDIGVTDNFFVIGGDSILS 2872
Query: 2122 IQVVSRARQAGVRFTPKDLFQHQTVQSLAAVAREGEGAVVLDQSALTGDLLLLPVQQAFF 2181
+Q+V++AR AG+ TP+ +F+ TVQ LA A G V SA + V A
Sbjct: 2873 LQIVAKARDAGLHVTPRMVFEAPTVQQLARAA----GPVPASASASLAGVEPSAVTSASA 2928
Query: 2182 ADDIPRRHHWNQSVV--LQPHQALQAPLLV-----------------------------A 2210
+ D+ R V + P LQ+ LL A
Sbjct: 2929 SSDLWRALGITPEHVEDVYPATPLQSGLLYHTLAESQQGAYLNQMRATLSGTLDVAAMHA 2988
Query: 2211 ALQALIVHHDALRIGFVQGAAGWSAAYRGPQQHQAEQVLWQT-TLNAVEELEALGEEAQR 2269
A QA + H LR GF G H++ + ++T +A + +A + R
Sbjct: 2989 AWQAALARHAILRTGFAWQHGGSVMQI----VHRSIALPFETHDWSAAPDYDARLAD-WR 3043
Query: 2270 SLDLSEG------PLLRAVLVDLADGSQRLLLVIHHLVVDGVSWRILLEDLQTAYRQVAQ 2323
+ DL++G PL+R L + L+ HHL++DG S +L ++ YR
Sbjct: 3044 ARDLADGIAPDEAPLMRIALFIRDAHTADLVWTHHHLLLDGWSVSLLFAEILRDYRLRTS 3103
Query: 2324 GAKVVLPAKTSAIRAWAERLQAYARSAALAQELAWWQ--TQLQGSPTGLPGA--DPQASL 2379
GA + R + E ++ A A AWW+ P L + +P+A+
Sbjct: 3104 GAAATF-EQAPPYRGYVEWIREAADDPATE---AWWRAWAARADDPATLTASLGEPRAAE 3159
Query: 2380 SNRHALSVTTHLDQVFTRRLLQDAPSAYRTQINDLLLTALARVVVRWTGDASMLIRLEGH 2439
HA LD+ RL A + +N L+ A A ++ R+ +
Sbjct: 3160 PGAHARRCA--LDEALVARLHATA-RRHEITLNTLMQGAWAVLLARYGHRRQVSYGTTLS 3216
Query: 2440 GREDLFDEIDLTRTVGWFTSLYPVKLVPTDSLAGSLKQIKEQLRAIPDKGLGFGALRYLG 2499
GR ++ R +G F + PV+ V D+ A LG + G
Sbjct: 3217 GRPAHLPGVE--RMLGLFINTLPVQ-VDVDASA----------------DLGAWLHKLQG 3257
Query: 2500 NAEAQQALSELPRPRITFNYLGQFDGSFDGGEQEGLFVPSGDGSGAEQSGEA-------- 2551
+ P R+ Q+ G + + V A + G+A
Sbjct: 3258 ELMELRHYEHTPLARVQ-----QWSGRSGDALFDSIVVFENYPVDAARDGDASLKVESID 3312
Query: 2552 -------PLGNWLEINGQVYAGELKLNWSFSQQMFDEATVQRLADDYAAELKALIEHCGV 2604
PL + G+ L L W+++ + D TV+R+A Y A L + +
Sbjct: 3313 SVDPTHYPLALAIIPRGKT----LSLEWAWNGERIDRETVERIALQYEAILDQMTDDVAR 3368
Query: 2605 NQG--VTPSDFPLARLSQAQLDSLPVTVA 2631
G P + A L + +SL + +A
Sbjct: 3369 RVGSLTLPGRYEAAPLQRYAFESLGMALA 3397
Score = 709 bits (1831), Expect = 0.0
Identities = 718/2461 (29%), Positives = 1079/2461 (43%), Gaps = 379/2461 (15%)
Query: 513 AREHPARQALALDDQTLSYGELNRQANRLAHYLIAQGVGPEVLVGIAVERSFAMVVSLLA 572
A E P AL L + +L + + RLA L+A+GV P V +A+ R A V ++LA
Sbjct: 19 AIERPDAVALVDSTGALVWRDLWQWSGRLAAALVAEGVRPGDRVVLALPRCTAFVAAILA 78
Query: 573 VLKAGGAYVPLDPEYPRERLVHMLDDSGVRLVLTQSHLRDR------------------- 613
V + YVPLDP P RL +D G R+V+T + L
Sbjct: 79 VWRVRACYVPLDPALPEARLRWQAEDCGARVVMTGAALTSGALDAVVEGVAADAVHATNA 138
Query: 614 ---------LP------------LPADLTALDIDLADAQLAQCAEHNPPTAFEPRSL--- 649
LP +P D A +D +A ++ H S+
Sbjct: 139 AMRTDGPRWLPEGVTTLDPQAFRVPDDAAAKALDTTNAASSEIFHHAMSGPSSDDSVLIW 198
Query: 650 -AYVIYTSGSTGKPKGVAISHAALSEFA-GIAAEYSRLVADDRVLQFATLNFDGFVEQLY 707
AYVIYTSGSTG+PKGV +SHAAL+ + G++ +A L
Sbjct: 199 PAYVIYTSGSTGRPKGVVLSHAALAAYLQGLSERLPEGIASAAYLSTT------------ 246
Query: 708 PALTLGATVVLRGPQLWDGADLYRQIIDQGITL-ADLPTAYWKLFLQDCLAAGPRPYGAL 766
A LG T + LW G L+ +ID + D AY D L P AL
Sbjct: 247 -AADLGHTSLFGA--LWHGWTLH--LIDADVAADPDAFAAYMHTHSVDLLKIVPSHLDAL 301
Query: 767 RQVH------------IGGEAMPLDGPVLWRRAGLG-HVRLLNTYGPTEATVVSSVLDCS 813
Q +GGE P + R A L +L+N YGPTE V VL +
Sbjct: 302 LQAQSAEWVLPRRCLVLGGEPAPTR--LAARIATLRPECQLINHYGPTETAV--GVLTRA 357
Query: 814 DDNAVMGATASPIGRALPGRGLYVLDPDLNLLPVGAVGELYIASAGGLARDYLQRPSLTA 873
A A P+G+ L ++D D N +P GA GEL I A +A YL RPSLTA
Sbjct: 358 --GAQTSAGTLPLGKPLAHVKARIVDADGNAVPKGAAGELCIGGAS-VAHGYLNRPSLTA 414
Query: 874 ERFVADPFSTLGERLYRTGDLARYRADGVIEYVGRVDHQVKIRGFRIELGEIEALLLAQE 933
ERFV DP G RLYRTGD +R DG ++GR+D Q+KIRGFR+E E+ A L +
Sbjct: 415 ERFVPDPDGN-GARLYRTGDRSRRLPDGEYAFLGRLDDQLKIRGFRVEPEEVAARLRNEH 473
Query: 934 AVREAFLLA------ADNQLVAYLVPAQPLSAAEQAAAGETLKATLREQLPDYMVPAHLI 987
VR+A ++A A +LVAYL A+ L E +++ L +LPDYMVP+ L
Sbjct: 474 GVRDAVVIAYADSDGAAPRLVAYLSAAESLDV-------EAIRSRLAAELPDYMVPSSLQ 526
Query: 988 FLDRMPLNPNGKLDRQALPKPDGSAVQQAWQAPVTPR---QQQVAAIWADILGVERVGLT 1044
L +PL PNGK+DR ALP P A A V PR ++ + IW +L + +G+T
Sbjct: 527 VLAALPLTPNGKIDRAALPAP--LQENTAGAARVEPRNDAERTLIGIWKLVLKRDDIGVT 584
Query: 1045 HHFFELGGHSLLAMQVVSRIR------------------QALKLEVPLKLLFE------- 1079
++FE+GG S+L++Q++++ R A ++ VP+K+ +
Sbjct: 585 DNYFEIGGDSILSLQIIAKARGAGLKLTPKQMFDHPTIEAAARVAVPMKVASDHRSAGEK 644
Query: 1080 -----QPRLEGFVAALATQDP---------DAPTAPALLPVGRDQPLPLSYAQERQWF-- 1123
Q G +T P DA + A P A + +WF
Sbjct: 645 GGGAKQRTSAGSTEQASTTTPIKTGERTRADASASHATAHAAATPPHTTQPADDDRWFAE 704
Query: 1124 ----------LWQLEP--QSAAYH---------IPSALRLK-GQLDLGALQRSFDTLLAR 1161
++ P Q +H S LRL L + ++ ++D ++AR
Sbjct: 705 AGVSRDAVDAVYPATPMQQGLLFHGMLDGEPGMYVSQLRLTIDSLKIDTMRAAWDAVIAR 764
Query: 1162 HESLRTH-----------LRQERDRTVQIISPQVSLQI-----------AHAEVHEAQLK 1199
H LRT + + R R + P+ +L + + E ++A +
Sbjct: 765 HPVLRTRFVWPAGGEPLQIVERRVRMPFELHPRDALVVPVPIAALTAAASTEEQYDAAYE 824
Query: 1200 ARVEAEIAQPFNLEQGPLLRVSLLRIAADEHVLVLVQHHIVSDGWSMQLMVEELVQLYAA 1259
A +A + F + PL+RV + H L+ HH ++DGWS +V E+ + YAA
Sbjct: 825 AARDAIATRGFEPDVAPLMRVDVFERPDGAHDLLWTHHHALTDGWSTAQVVSEVARAYAA 884
Query: 1260 YSQGQVLQW-PALPIQYADYAVWQRN-------WMEAGEKARQLAYWRDMLGGEQSVLAL 1311
G V PA P YADY W R W + A D LGG AL
Sbjct: 885 LDAGGVPDTSPAAP--YADYVHWLRGQPDTAPFWRARLATRDEPARVADALGG-----AL 937
Query: 1312 PFDHPRPAVQSHRGARLAFELPGALTQGLKALAKQQDVTLFMLLLASFQTLLHRYSGQEE 1371
+ A L EL G L A++ VTL L+ A++ L R+SG+ +
Sbjct: 938 RASSEKSA-DGVAAQALIRELDGPSHARLTRAARRAQVTLNTLVQAAWALALARFSGRTQ 996
Query: 1372 IRVGVPIANR--NRSETERLIGFFVNTQVLKADLHGQMSVEQLLQQARQRALDAQAHQDL 1429
+ G+ ++ R + + ++G F+N+ L D+ +V L +++ + + +
Sbjct: 997 VTFGMTVSGRPVDLPNAQSIVGLFINSLPLWVDVKSDATVRSWLAALQRQNAELRDVEHT 1056
Query: 1430 PFEQLVEALQPERSLSHNPLFQ--VMFNHQTDVGQAQVQQQLPNLSVEGLEWESKTAHFD 1487
P + +LQ + + + LF ++F + +P + S HF
Sbjct: 1057 P----LASLQQWANSNVDALFDSLIVFENYPLDDALDALGDVPRIRAVDAHNRS---HFP 1109
Query: 1488 LDLDIQESTEGIWATLGYAQDLFEAST----VQRMARHWQNLLQGMVA------DPRQTL 1537
L L + G L A+ V R+A++++ +L + DP L
Sbjct: 1110 LMLVVAPRHVGGGDALRLEWHRHAATVSEEGVARIAKYFERMLDCLATALVEGDDPHVRL 1169
Query: 1538 SQLNLLDNTERQQILQRWDQSDAGFSAKRLVHELVADRAGETPEAVAVKFGEQQLTYGEL 1597
L D + + + F+ + + + A +A PEA+A+ G++ +TY +L
Sbjct: 1170 RDLPTDDAPSAKS-----PRLPSTFAYEPVTARIAA-QARARPEAIALIDGDEHVTYAQL 1223
Query: 1598 DRQANRLAHALIARGVGPEVRVAIAMPRSAEIMVAFLAVMKAGGVYVPLDIEYPRDRLLY 1657
D + +A L G E RV +AM R A ++ + L V++AG YVPLD YP RL +
Sbjct: 1224 DVWSRAIADELRRLGATAETRVGVAMQRGAALVASLLGVLRAGAAYVPLDPSYPVGRLAH 1283
Query: 1658 MMQDSRARLLLT-------HSTVQQRLPIPDGL---EALAVDQTQAWSANDDSAPEVVLD 1707
++ D++ RL++T H+++ P D + +A+ D T +A+ + P
Sbjct: 1284 IVDDAQLRLIVTDASSLAQHASLFGSRPTVDAVALRDAVPADATGDDTADAGAYPHP--- 1340
Query: 1708 GDNLAYVIYTSGSTGMPKGVAVSHGPLVAHIIATGERYETSPADCELHFMSFAFDGSHEG 1767
LAYVIYTSGSTG+PKGV V+H + AT R+ D F S+AFD S
Sbjct: 1341 -QQLAYVIYTSGSTGVPKGVGVTHENVARLFDATQSRFAFDAQDVWTLFHSYAFDFSVWE 1399
Query: 1768 WMHPLINGAS-VLIRDDSLWLPEYTYQQMHRHHVTMAVFPPVYLQQLAEHAERDGNP-PK 1825
L++GA V++ S P + + + VT+ P QL + DGN
Sbjct: 1400 IFGALVHGARLVIVPHWSAREPAAFHALLRKERVTVLNQTPSAFVQLIQ--ADDGNTLDS 1457
Query: 1826 VRVYCFGGDAVAQASYDLAW------RALKPTYLFNGYGPTETVVTPL---LWKARKGDP 1876
+R FGG+ + +S W + + P L N YG TET V L +A D
Sbjct: 1458 LRAVIFGGERLEPSSL-ARWAEGARRKGVLPA-LVNMYGITETTVHVTHRTLDEAALRDG 1515
Query: 1877 CGAVYAPIGTLLGNRSGYVLDAQLNLQPIGVAGELYLGGEGVARGYLERPALTAERFVPD 1936
+ AP+ L + +VLDA LN P+G GELY+GG G+ARGYL R AL+A+RFVPD
Sbjct: 1516 RSVIGAPLDDL----TLHVLDADLNRVPLGAVGELYVGGAGLARGYLGRAALSAQRFVPD 1571
Query: 1937 PFGKPGSRVYRSGDLTRGRPDGGVDYLGRVDHQVKIRGFRIELGEIEARLREQDSVGETV 1996
P+G PG+R+Y SGDL R PDG ++YLGR D QVKIRGFRIELGEI+A LR V +
Sbjct: 1572 PYGAPGARLYSSGDLARRLPDGDLEYLGRNDDQVKIRGFRIELGEIQAALRAHPEVRDVA 1631
Query: 1997 VVAQEGPSG------KQLVAYVVPLDPLLIDDAVAQSTCREALRRALKARLPDYMVPTHL 2050
V+ +G ++L+AYVVP DA T L ARLP +MVP+
Sbjct: 1632 VLVSGHGNGNNANDNRRLIAYVVPRGGPNAGDAGRWQTW-------LAARLPGHMVPSSY 1684
Query: 2051 MFLERMPLTPNGKLDRKGLPRPDVSQMQQ-VYVAPQSELEQKIAAIWSDVLRLPRVGLHD 2109
+ LER PLT NGKLDR+ LP P+V+ + YVAP E + K+AAIW VL + RVG HD
Sbjct: 1685 VELERFPLTLNGKLDRRALPAPEVANSSRATYVAPHGETQTKLAAIWQQVLGVERVGAHD 1744
Query: 2110 NFFELGGDSIISIQVVSRARQA-GVRFTPKDLFQHQTVQSLAAVAREGEGAVVLDQSALT 2168
+FF LGG S+++++V+S R G + +F+H ++ A + + A D ALT
Sbjct: 1745 DFFLLGGHSLLAVRVLSAVRTVFGDAPGLRAVFEHPRLEDFATLLSAAQSAGA-DDGALT 1803
Query: 2169 ----------GDLLLLPVQQAFFADDIPRRHHWNQSVVLQPHQ----------------- 2201
GD L V A A D+ R+ + L P Q
Sbjct: 1804 SASGVAVAADGDAAALSVTAAVTAADVARQADVTAPMPLSPSQQSLWFLWKLDPHSVAYH 1863
Query: 2202 ---------ALQAPLLVAALQALIVHHDALRIGFVQGAAGWSAAYRGPQQHQAEQVLWQT 2252
L L AA +L H ALR+ F + + + +
Sbjct: 1864 VNGALRFDGQLDVDALRAAFVSLGKRHPALRMRFAEIEGVPYQRIDDTCRSEIRLLDLPN 1923
Query: 2253 TLNAVEE---LEALGEEAQRSLDLSEGPLLRAVLVDLADGSQRLLLVIHHLVVDGVSWRI 2309
T N E LG + DLS P +RA LV +AD L LV+HH+V D S +
Sbjct: 1924 THNDTSEEALAACLGALVRTPFDLSAEPPVRATLVRMADDCHVLHLVLHHIVSDDWSLGL 1983
Query: 2310 LLEDLQTAYR---------QVAQGAKVVLPAKTSAIRAWAERLQAYARSAALA-----QE 2355
L D YR V A + + +A A A R AR+A L Q+
Sbjct: 1984 LFADFSRLYRDYCAAGPAASVTSVASIADDERIAATSAAAYRELISARAARLTPERELQQ 2043
Query: 2356 LAWWQTQLQGS---------PTGLPGADPQASLSNRHALSVTTHLDQVFTRRLLQDAPSA 2406
LAWW+ L P + + + RH + V T L+ SA
Sbjct: 2044 LAWWRAALTNDDESPATLALPYDRTRSGSRCAPGARHRVRVPAG-----TAHALRALASA 2098
Query: 2407 YRTQINDLLLTALARVVVRWTGDASMLIRLEGHGREDLFDEIDLTRTVGWFTSLYPVKLV 2466
R + LL A+ ++ R++G + + + + GR DL D+ G+F + ++
Sbjct: 2099 RRATLFMTLLAAVDALLYRYSGQSDIRLGVPLAGR-DLPGAADV---AGFFVNTVVIRTT 2154
Query: 2467 PTDS--LAGSLKQIKEQ-LRAIPDKGLGFGALRYLGNAEAQQALSELPRPRITFNYLGQF 2523
P A + ++E+ L A ++ + F ++ + + ++ L++ P ++ N +
Sbjct: 2155 PRGETRAAQLIDDVRERLLGAYANQDVPFASV--VKAVQPERDLAQTPLFQVLVNQQQRH 2212
Query: 2524 DGSFDGGEQEGLFVPSGDGSGAEQSGEAPLGNWLEINGQVYAGELKLNWSFSQQMFDEAT 2583
D + GE + V D +GEA L I + G + L ++++ +FD +T
Sbjct: 2213 DLAASFGEGLRVTVQEVD------NGEAQFDLMLNI-AEAADGAIDLAFTYATDVFDAST 2265
Query: 2584 VQRLADDYAAELKALIEHCGVNQGVTPSDFPLARLSQAQLDSLPVTVADIEDVYPLSPMQ 2643
++RLA ++ L++ + F L L LP T A E V Q
Sbjct: 2266 IERLARNFT----GLLDQWSAAPDARIASFELPELGDQPSPRLPSTFA-YEPVTTRIAAQ 2320
Query: 2644 QGMLFQSLYGEGSGDYINQMRIDVEGLDVPRFRQAWQAAVDSHEILRSGFLWQTEFEQPL 2703
+++ +++ ++DV W A+ +HE+ R G +T +
Sbjct: 2321 ARARPEAVALVDGDEHVTYAQLDV-----------WSRAI-AHELRRLGATAETRVGVAM 2368
Query: 2704 Q 2704
Q
Sbjct: 2369 Q 2369
Score = 647 bits (1669), Expect = 0.0
Identities = 426/1115 (38%), Positives = 609/1115 (54%), Gaps = 66/1115 (5%)
Query: 2576 QQMFDEATVQRLA---DDYAAELKALIEHCGVNQGVTPSDFPLARLSQAQLDSLPVTVAD 2632
+ +F+ TVQ+LA A A + GV PS A S +L +T
Sbjct: 2889 RMVFEAPTVQQLARAAGPVPASASASLA------GVEPSAVTSASASSDLWRALGITPEH 2942
Query: 2633 IEDVYPLSPMQQGMLFQSLYGEGSGDYINQMRIDVEG-LDVPRFRQAWQAAVDSHEILRS 2691
+EDVYP +P+Q G+L+ +L G Y+NQMR + G LDV AWQAA+ H ILR+
Sbjct: 2943 VEDVYPATPLQSGLLYHTLAESQQGAYLNQMRATLSGTLDVAAMHAAWQAALARHAILRT 3002
Query: 2692 GFLWQTEFEQPLQVVYKQMRMPFAELDWQGRPDSSAALDSLAESARAQGFVLEQAPLLSL 2751
GF WQ +Q+V++ + +PF DW PD A L A G ++APL+ +
Sbjct: 3003 GFAWQ-HGGSVMQIVHRSIALPFETHDWSAAPDYDARLADWRARDLADGIAPDEAPLMRI 3061
Query: 2752 TVVRTGASRYHLIYTNHHILMDGWSGSQLFGEVLQHY-------AGEPLRAPIGRYRDYI 2804
+ A L++T+HH+L+DGWS S LF E+L+ Y A +AP YR Y+
Sbjct: 3062 ALFIRDAHTADLVWTHHHLLLDGWSVSLLFAEILRDYRLRTSGAAATFEQAP--PYRGYV 3119
Query: 2805 AWL-QAQDKSVSEAFWKAQLLNLQEPTRLARGLQAAQSEALAVNGEH--RLNLDASQTAQ 2861
W+ +A D +EA+W+A +P L L ++ A G H R LD + A+
Sbjct: 3120 EWIREAADDPATEAWWRAWAARADDPATLTASLGEPRA---AEPGAHARRCALDEALVAR 3176
Query: 2862 LKAFAQRHKVTLNTLVQSAWLLLLQHHTGQATVAFGATVAGRPAQLRGIEQQVGLFINTL 2921
L A A+RH++TLNTL+Q AW +LL + + V++G T++GRPA L G+E+ +GLFINTL
Sbjct: 3177 LHATARRHEITLNTLMQGAWAVLLARYGHRRQVSYGTTLSGRPAHLPGVERMLGLFINTL 3236
Query: 2922 PVVATPDAQMTVSQWLQQIQAQNVRLREQEHTPLFEIQRWAGLGGEALFDSILVFENYPV 2981
PV DA + WL ++Q + + LR EHTPL +Q+W+G G+ALFDSI+VFENYPV
Sbjct: 3237 PVQVDVDASADLGAWLHKLQGELMELRHYEHTPLARVQQWSGRSGDALFDSIVVFENYPV 3296
Query: 2982 SEALEQGAPSGLTFGAVHSLEQTHYPLTV-LLGIGDTLGMEFNYDRHAFSAAHIEQLAEH 3040
A + A L ++ S++ THYPL + ++ G TL +E+ ++ +E++A
Sbjct: 3297 DAARDGDA--SLKVESIDSVDPTHYPLALAIIPRGKTLSLEWAWNGERIDRETVERIALQ 3354
Query: 3041 FQQLLQALAVDGAQRLATLPSLASTERETVLHAWNATAADYPLHLAVHQLIEAQVVRTPD 3100
++ +L + D A+R+ +L T+ + A ++ + AQ R+PD
Sbjct: 3355 YEAILDQMTDDVARRVGSL---------TLPGRYEAAPLQRYAFESLGMALAAQAKRSPD 3405
Query: 3101 APALVFAGQVLSYAALNRRANRLAHRLIAAGVGPDVLVGLAVERSIEMVVGLLAVLKAGG 3160
A AL + L+YA L+ + LA RL+A GVG + VGL V R +V LL ++++GG
Sbjct: 3406 AIALRCEDESLTYAELDAWSAMLAARLVARGVGAERRVGLCVARGPALVAALLGIIRSGG 3465
Query: 3161 AYVPLDPEYPRDRLAYMLQDSDVKLLLTQAHLLEQ----------LPIPTGLHSLVLEQG 3210
A+VPLDPEYP RLA M+ D+ + ++ + +Q + + T H VL
Sbjct: 3466 AFVPLDPEYPPARLAQMIDDAGIVEVVADSASAKQVAAVLAGCEVVEVRTTQHDAVLSA- 3524
Query: 3211 DEWLQAYAEQNPLVTVDGENLAYVIYTSGSTGQPKGAGNRHSALTNRLCWMQHAYGLEGS 3270
E A A + + LAYV+YTSGSTG+PKG G H AL L YG++G+
Sbjct: 3525 -ETATAAAPHFLDAPLHPDQLAYVLYTSGSTGRPKGVGVSHGALWTHLQDFLATYGIDGT 3583
Query: 3271 DTVLQKTPFSFDVSVWEFFWPLMTGARLVVAAPGDHRDPARLVSLINAEHVTTLHFVPSM 3330
DTVL + +FDV++ E L+ GA + + D L + VT ++
Sbjct: 3584 DTVLHSSTINFDVALHETLPALLRGATVEMRGT-QPWDLQSLSERLVKRRVTFARIPTAL 3642
Query: 3331 LQAFLQDAGVGACHSLQRIVCSGEALPVDA-QQQVFAKLPHAGLYNLYGPTEAAIDVTH- 3388
Q + + A A +L+++ GEALP DA + L L NLYGPTE + +
Sbjct: 3643 WQQWQRHAPPRAQLALRQVTVGGEALPGDALARWREGPLADIRLDNLYGPTETTVAALYR 3702
Query: 3389 WTCVDEGRD-AVPIGRPIANLGCYVLDGNLEPAPVGVLGELYLGGVGLARGYHRRPALTA 3447
T D+ R VPIG P V D + APVG LGEL +GG +ARGY R ALTA
Sbjct: 3703 RTGADDARQVTVPIGHPYPGRTARVFDAFGDEAPVGGLGELCIGGPTVARGYQGRAALTA 3762
Query: 3448 ERFVTDPFGS-GSRLYRTGDLARYRDDGVIEYAGRIDHQVKLRGLRIELGEIEARLLEHA 3506
ERFV DP+G G+R+YR+GDL R R DG E+ GR+D QVKLRG RIELGEIEA L +
Sbjct: 3763 ERFVPDPYGEPGARVYRSGDLCRVRADGTAEFLGRLDQQVKLRGQRIELGEIEAVLRQCE 3822
Query: 3507 CVREAAVLAV---DGTHLVGYLVLQA-----PSEDWKAQVAMHLAAQLPDYMVPAQWVVL 3558
VREAAV+ V L Y+ Q+ P+ D ++ L +LP YMVP+ VL
Sbjct: 3823 GVREAAVIVVGPAQKQRLAAYVAGQSDAASLPTVD-AQRLQRELERKLPGYMVPSSITVL 3881
Query: 3559 TQMPLSPNGKLDRKALPKPEAQGAGAYQAPQSAIEQQVAAIWRDVLGVERVGLNDNFFEL 3618
++P PNGKLDR +LP P+A GA AP + +E + +IW VLG + +G+ DNFFE
Sbjct: 3882 ARLPWMPNGKLDRASLPAPQA-GAIERVAPSNEVEAALLSIWAAVLGRDDLGVTDNFFEA 3940
Query: 3619 GGHSLLVLMLKERIRKVSGVGLSVSQLMLNPTVRG 3653
GG S+ L + R R+ +G L+ Q+ +PTV G
Sbjct: 3941 GGDSIQSLQIIARARE-AGWRLTPRQVFEHPTVAG 3974
Score = 625 bits (1613), Expect = 0.0
Identities = 409/1076 (38%), Positives = 584/1076 (54%), Gaps = 90/1076 (8%)
Query: 2633 IEDVYPLSPMQQGMLFQSLYGEGSGDYINQMRIDVEGLDVPRFRQAWQAAVDSHEILRSG 2692
++ VYP +PMQQG+LF + G Y++Q+R+ ++ L + R AW A + H +LR+
Sbjct: 712 VDAVYPATPMQQGLLFHGMLDGEPGMYVSQLRLTIDSLKIDTMRAAWDAVIARHPVLRTR 771
Query: 2693 FLWQTEFEQPLQVVYKQMRMPFA--ELDWQGRPDSSAAL----------DSLAESAR--- 2737
F+W E PLQ+V +++RMPF D P AAL D+ E+AR
Sbjct: 772 FVWPAGGE-PLQIVERRVRMPFELHPRDALVVPVPIAALTAAASTEEQYDAAYEAARDAI 830
Query: 2738 -AQGFVLEQAPLLSLTVVRTGASRYHLIYTNHHILMDGWSGSQLFGEVLQHYA-----GE 2791
+GF + APL+ + V + L++T+HH L DGWS +Q+ EV + YA G
Sbjct: 831 ATRGFEPDVAPLMRVDVFERPDGAHDLLWTHHHALTDGWSTAQVVSEVARAYAALDAGGV 890
Query: 2792 PLRAPIGRYRDYIAWLQAQDKSVSEAFWKAQLLNLQEPTRLARGLQAA-------QSEAL 2844
P +P Y DY+ WL+ Q + FW+A+L EP R+A L A ++ +
Sbjct: 891 PDTSPAAPYADYVHWLRGQPDTAP--FWRARLATRDEPARVADALGGALRASSEKSADGV 948
Query: 2845 AVNGEHRLNLDASQTAQLKAFAQRHKVTLNTLVQSAWLLLLQHHTGQATVAFGATVAGRP 2904
A R LD A+L A+R +VTLNTLVQ+AW L L +G+ V FG TV+GRP
Sbjct: 949 AAQALIR-ELDGPSHARLTRAARRAQVTLNTLVQAAWALALARFSGRTQVTFGMTVSGRP 1007
Query: 2905 AQLRGIEQQVGLFINTLPVVATPDAQMTVSQWLQQIQAQNVRLREQEHTPLFEIQRWAGL 2964
L + VGLFIN+LP+ + TV WL +Q QN LR+ EHTPL +Q+WA
Sbjct: 1008 VDLPNAQSIVGLFINSLPLWVDVKSDATVRSWLAALQRQNAELRDVEHTPLASLQQWANS 1067
Query: 2965 GGEALFDSILVFENYPVSEALEQGAPSGLTFGAVHSLEQTHYPLTVL-----LGIGDTLG 3019
+ALFDS++VFENYP+ +AL+ AV + ++H+PL ++ +G GD L
Sbjct: 1068 NVDALFDSLIVFENYPLDDALD-ALGDVPRIRAVDAHNRSHFPLMLVVAPRHVGGGDALR 1126
Query: 3020 MEFNYDRHAFSAAHIEQLAEHFQQLLQALA---VDGAQRLATLPSLASTERETVLHAWNA 3076
+E++ S + ++A++F+++L LA V+G L L + + A +A
Sbjct: 1127 LEWHRHAATVSEEGVARIAKYFERMLDCLATALVEGDDPHVRLRDLPTDD------APSA 1180
Query: 3077 TAADYPLHLA---VHQLIEAQVVRTPDAPALVFAGQVLSYAALNRRANRLAHRLIAAGVG 3133
+ P A V I AQ P+A AL+ + ++YA L+ + +A L G
Sbjct: 1181 KSPRLPSTFAYEPVTARIAAQARARPEAIALIDGDEHVTYAQLDVWSRAIADELRRLGAT 1240
Query: 3134 PDVLVGLAVERSIEMVVGLLAVLKAGGAYVPLDPEYPRDRLAYMLQDSDVKLLLTQAHLL 3193
+ VG+A++R +V LL VL+AG AYVPLDP YP RLA+++ D+ ++L++T A L
Sbjct: 1241 AETRVGVAMQRGAALVASLLGVLRAGAAYVPLDPSYPVGRLAHIVDDAQLRLIVTDASSL 1300
Query: 3194 EQLPIPTG----LHSLVLEQ-------GDEWLQAYAEQNPLVTVDGENLAYVIYTSGSTG 3242
Q G + ++ L GD+ A A +P + LAYVIYTSGSTG
Sbjct: 1301 AQHASLFGSRPTVDAVALRDAVPADATGDDTADAGAYPHP------QQLAYVIYTSGSTG 1354
Query: 3243 QPKGAGNRHSALTNRLCWMQHAYGLEGSDTVLQKTPFSFDVSVWEFFWPLMTGARLVVAA 3302
PKG G H + Q + + D ++FD SVWE F L+ GARLV+
Sbjct: 1355 VPKGVGVTHENVARLFDATQSRFAFDAQDVWTLFHSYAFDFSVWEIFGALVHGARLVIVP 1414
Query: 3303 PGDHRDPARLVSLINAEHVTTLHFVPSMLQAFLQDAGVGACHSLQRIVCSGEALPVDAQQ 3362
R+PA +L+ E VT L+ PS +Q SL+ ++ GE L +
Sbjct: 1415 HWSAREPAAFHALLRKERVTVLNQTPSAFVQLIQADDGNTLDSLRAVIFGGERLEPSSLA 1474
Query: 3363 QVFAKLPHAG----LYNLYGPTEAAIDVTHWT----CVDEGRDAVPIGRPIANLGCYVLD 3414
+ G L N+YG TE + VTH T + +GR IG P+ +L +VLD
Sbjct: 1475 RWAEGARRKGVLPALVNMYGITETTVHVTHRTLDEAALRDGRSV--IGAPLDDLTLHVLD 1532
Query: 3415 GNLEPAPVGVLGELYLGGVGLARGYHRRPALTAERFVTDPFGS-GSRLYRTGDLARYRDD 3473
+L P+G +GELY+GG GLARGY R AL+A+RFV DP+G+ G+RLY +GDLAR D
Sbjct: 1533 ADLNRVPLGAVGELYVGGAGLARGYLGRAALSAQRFVPDPYGAPGARLYSSGDLARRLPD 1592
Query: 3474 GVIEYAGRIDHQVKLRGLRIELGEIEARLLEHACVREAAVL---------AVDGTHLVGY 3524
G +EY GR D QVK+RG RIELGEI+A L H VR+ AVL A D L+ Y
Sbjct: 1593 GDLEYLGRNDDQVKIRGFRIELGEIQAALRAHPEVRDVAVLVSGHGNGNNANDNRRLIAY 1652
Query: 3525 LVLQ-APSEDWKAQVAMHLAAQLPDYMVPAQWVVLTQMPLSPNGKLDRKALPKPEAQGA- 3582
+V + P+ + LAA+LP +MVP+ +V L + PL+ NGKLDR+ALP PE +
Sbjct: 1653 VVPRGGPNAGDAGRWQTWLAARLPGHMVPSSYVELERFPLTLNGKLDRRALPAPEVANSS 1712
Query: 3583 -GAYQAPQSAIEQQVAAIWRDVLGVERVGLNDNFFELGGHSLLVLMLKERIRKVSG 3637
Y AP + ++AAIW+ VLGVERVG +D+FF LGGHSLL + + +R V G
Sbjct: 1713 RATYVAPHGETQTKLAAIWQQVLGVERVGAHDDFFLLGGHSLLAVRVLSAVRTVFG 1768
Score = 533 bits (1373), Expect = e-154
Identities = 467/1585 (29%), Positives = 728/1585 (45%), Gaps = 152/1585 (9%)
Query: 80 LQGRLDLAALQRAFDSLLARHESLRTRLV-QDGERLLQNVAPEARIEIRQD----VADEQ 134
L G LD+AA+ A+ + LARH LRT Q G ++Q V + D
Sbjct: 2977 LSGTLDVAAMHAAWQAALARHAILRTGFAWQHGGSVMQIVHRSIALPFETHDWSAAPDYD 3036
Query: 135 QLLARVEA-EIARPFDLQAGPLLRVSLLQLAEDEHV--LVMVQHHIISDGWSMQVMVEEL 191
LA A ++A PL+R++L D H LV HH++ DGWS+ ++ E+
Sbjct: 3037 ARLADWRARDLADGIAPDEAPLMRIALF--IRDAHTADLVWTHHHLLLDGWSVSLLFAEI 3094
Query: 192 VQFYAAHSQGREVQLPGLPIHYADYALWQRSWMEAGEKARQLAYWQDLLG--GEQPVLEL 249
++ Y + G P Y Y W R EA + A+W+ + L
Sbjct: 3095 LRDYRLRTSGAAATFEQAP-PYRGYVEWIR---EAADDPATEAWWRAWAARADDPATLTA 3150
Query: 250 PLDHPRPAQQSHCGASLQVHLPADLVAGIKRLAQQEGVTPFMLLLASFQTLLFRYSGQSD 309
L PR A+ + + L LVA + A++ +T L+ ++ LL RY +
Sbjct: 3151 SLGEPRAAEPG--AHARRCALDEALVARLHATARRHEITLNTLMQGAWAVLLARYGHRRQ 3208
Query: 310 IRIGVPNANR--NRVETERLIGFFVNTQVLKADLDGQMSFAELLQQAKRRSLEAQAHQDL 367
+ G + R + ER++G F+NT ++ D+D L + + +E + ++
Sbjct: 3209 VSYGTTLSGRPAHLPGVERMLGLFINTLPVQVDVDASADLGAWLHKLQGELMELRHYEHT 3268
Query: 368 PFEQLVVALQPERSLSHNPLFQ---VMFNHQTDAQGGRDGQQLPGLRVAQLDWENQTTHF 424
P ++ Q S + LF V N+ DA RDG L+V +D TH+
Sbjct: 3269 PLARV----QQWSGRSGDALFDSIVVFENYPVDA--ARDGDA--SLKVESID-SVDPTHY 3319
Query: 425 DLSLDTHESAEGLWAALTYATDLFESATIERLAQHWQNLLQAAVSAPRSRLCVLSMLDAP 484
L+L + L + + + T+ER+A ++ +L R+ L++
Sbjct: 3320 PLALAIIPRGKTLSLEWAWNGERIDRETVERIALQYEAILDQMTDDVARRVGSLTLPGRY 3379
Query: 485 EQQRMLKDWNAPATVAAPHAVHQLFEAQAREHPARQALALDDQTLSYGELNRQANRLAHY 544
E AP A ++ AQA+ P AL +D++L+Y EL+ + LA
Sbjct: 3380 EA--------APLQRYAFESLGMALAAQAKRSPDAIALRCEDESLTYAELDAWSAMLAAR 3431
Query: 545 LIAQGVGPEVLVGIAVERSFAMVVSLLAVLKAGGAYVPLDPEYPRERLVHMLDDSGVRLV 604
L+A+GVG E VG+ V R A+V +LL ++++GGA+VPLDPEYP RL M+DD+G+ V
Sbjct: 3432 LVARGVGAERRVGLCVARGPALVAALLGIIRSGGAFVPLDPEYPPARLAQMIDDAGIVEV 3491
Query: 605 LTQSHLRDRLP--------LPADLTALDIDLADAQLAQCAEHNPPTAFEPRSLAYVIYTS 656
+ S ++ + T D L+ A H P LAYV+YTS
Sbjct: 3492 VADSASAKQVAAVLAGCEVVEVRTTQHDAVLSAETATAAAPHFLDAPLHPDQLAYVLYTS 3551
Query: 657 GSTGKPKGVAISHAAL-SEFAGIAAEYSRLVADDRVLQFATLNFDGFVEQLYPALTLGAT 715
GSTG+PKGV +SH AL + A Y + D VL +T+NFD + + PAL GAT
Sbjct: 3552 GSTGRPKGVGVSHGALWTHLQDFLATYG-IDGTDTVLHSSTINFDVALHETLPALLRGAT 3610
Query: 716 VVLRGPQLWDGADLYRQIIDQGITLADLPTAYWKLFLQDCLAAGPRPYGALRQVHIGGEA 775
V +RG Q WD L +++ + +T A +PTA W+ + + A PR ALRQV +GGEA
Sbjct: 3611 VEMRGTQPWDLQSLSERLVKRRVTFARIPTALWQQWQRH---APPRAQLALRQVTVGGEA 3667
Query: 776 MPLDGPVLWRRAGLGHVRLLNTYGPTEATVVSSVLDCSDDNAVMGATASPIGRALPGRGL 835
+P D WR L +RL N YGPTE TV + D+A PIG PGR
Sbjct: 3668 LPGDALARWREGPLADIRLDNLYGPTETTVAALYRRTGADDARQ--VTVPIGHPYPGRTA 3725
Query: 836 YVLDPDLNLLPVGAVGELYIASAGGLARDYLQRPSLTAERFVADPFSTLGERLYRTGDLA 895
V D + PVG +GEL I +AR Y R +LTAERFV DP+ G R+YR+GDL
Sbjct: 3726 RVFDAFGDEAPVGGLGELCIGGPT-VARGYQGRAALTAERFVPDPYGEPGARVYRSGDLC 3784
Query: 896 RYRADGVIEYVGRVDHQVKIRGFRIELGEIEALLLAQEAVREAFLLA---ADNQLVAYLV 952
R RADG E++GR+D QVK+RG RIELGEIEA+L E VREA ++ A Q +A V
Sbjct: 3785 RVRADGTAEFLGRLDQQVKLRGQRIELGEIEAVLRQCEGVREAAVIVVGPAQKQRLAAYV 3844
Query: 953 PAQPLSAAEQAAAGETLKATLREQLPDYMVPAHLIFLDRMPLNPNGKLDRQALPKPDGSA 1012
Q +A+ + L+ L +LP YMVP+ + L R+P PNGKLDR +LP P A
Sbjct: 3845 AGQSDAASLPTVDAQRLQRELERKLPGYMVPSSITVLARLPWMPNGKLDRASLPAPQAGA 3904
Query: 1013 VQQAWQAPVTPRQQQVAAIWADILGVERVGLTHHFFELGGHSLLAMQVVSRIRQALKLEV 1072
+++ AP + + +IWA +LG + +G+T +FFE GG S+ ++Q+++R R+A
Sbjct: 3905 IERV--APSNEVEAALLSIWAAVLGRDDLGVTDNFFEAGGDSIQSLQIIARAREAGWRLT 3962
Query: 1073 PLKLLFEQPRLEGFVAALATQDPDAPTAPALLPVGRDQPLPLSYAQERQWFLWQLEPQSA 1132
P + +FE P + G Q A A+ + LPL+ Q ++ PQ
Sbjct: 3963 P-RQVFEHPTVAGLA-----QRAQRLEAGAVQEIDDGAALPLTPIQR---LFFERYPQGE 4013
Query: 1133 AYHIPSAL-RLKGQLDLGALQRSFDTLLARHESLRTHLRQERDRTVQII----------- 1180
++ + L ++KG+L AL+R+ L ARH++LR +E Q+
Sbjct: 4014 SHWNQAVLLKVKGRLVPAALERAVAALEARHDALRLRFVKEAGEWKQVAVKAAGTSEAER 4073
Query: 1181 SPQVSLQIAHAEVHEAQLKARVEAE---------------------------------IA 1207
+P S Q+++A + +A +E I
Sbjct: 4074 APNAS-QVSNASDASEEAQASRTSEPLQTSQPSQSASTTVVHHDHLTSLAGLTAACDRIQ 4132
Query: 1208 QPFNLEQGPLLRVSLLRIAADEHVLVLVQHHIVSDGWSMQLMVEELVQLYAAYSQGQVLQ 1267
N+E GP+ R+ + VL+ + HH+ DG S ++++EEL AY Q + +
Sbjct: 4133 SSLNIEHGPVWRIGHFETPDETRVLIAI-HHLAVDGVSWRVLLEEL---QTAYEQAERDE 4188
Query: 1268 WPALPIQYADYAVWQR---NWMEAGEKARQLAYWRDMLGGEQSVLALPFDHPRPAVQSHR 1324
ALP + W R + E+ E+ +LA+W+ L ++ A P P + +
Sbjct: 4189 PIALPAPSMSWRAWVRAINQYAESSERVSELAWWQTSLDA-PALRAGPLFPPLSSHPQPQ 4247
Query: 1325 GARLAFELPGALTQGLKALAKQQDVTLFMLLLASFQTLLHRYSGQEEIRVGVPIANR--- 1381
L P + L+ + + + +LLA+ + ++E+ V + R
Sbjct: 4248 KTLLKKLSPDMTAELLREAPRAYKMRVDEVLLAALVRAIGDTVARDEVLVELEGHGREDV 4307
Query: 1382 -NRSETERLIGFFVNTQVLKADLHGQMSVEQLLQQARQRALDAQAH----------QDLP 1430
++ R +G+F TQ A G S + LL + R+R D
Sbjct: 4308 IEGADLSRTVGWF-TTQYPLALPRGVDSADSLL-RVRERLAAVPLRGLGWGLLACCADAA 4365
Query: 1431 FEQLVEAL-QPERSLSHNPLFQVMFNHQTDVGQAQVQQQLPNLSVEGLEWESKTAHFDLD 1489
+ + AL PE ++ F F+ ++ G A P S + + ++ LD
Sbjct: 4366 SQSALRALPSPEIGFNYLGRFDQTFDGESRFGFA------PESSGDAIAPHARIPDRALD 4419
Query: 1490 LDIQESTEGIWATLGYAQDLFEASTVQRMARHWQNLLQGMVADPRQTLSQ----LNLLDN 1545
++ + + GYA + + +++ L ++A R SQ +L
Sbjct: 4420 INGWIAGNSLTFNWGYAPQFLSDELAEELFASFESALGELLAHLRTATSQPQMSASLKAV 4479
Query: 1546 TERQQILQRWDQSDAGFSAKRLVHE 1570
E + L R D A ++A R V+E
Sbjct: 4480 PESLEALARRDAVAASWAA-RAVYE 4503
Score = 439 bits (1129), Expect = e-126
Identities = 374/1137 (32%), Positives = 527/1137 (46%), Gaps = 94/1137 (8%)
Query: 2589 DDYAAELKALIEHCGVNQGVTPSDFPLARLSQAQLDSLPVTVA----------DIEDVYP 2638
+D+A L A + G + G S +A + +L VT A D+ P
Sbjct: 1783 EDFATLLSAA-QSAGADDGALTSASGVAVAADGDAAALSVTAAVTAADVARQADVTAPMP 1841
Query: 2639 LSPMQQGMLFQSLYGEGSGDYINQMRIDVEG-LDVPRFRQAWQAAVDSHEILRSGFLWQT 2697
LSP QQ + F S Y + +G LDV R A+ + H LR F
Sbjct: 1842 LSPSQQSLWFLWKLDPHSVAYHVNGALRFDGQLDVDALRAAFVSLGKRHPALRMRF---A 1898
Query: 2698 EFEQ-PLQVVYKQMRMPFAELDWQGRPD--SSAALDSLAESARAQGFVLEQAPLLSLTVV 2754
E E P Q + R LD + S AL + + F L P + T+V
Sbjct: 1899 EIEGVPYQRIDDTCRSEIRLLDLPNTHNDTSEEALAACLGALVRTPFDLSAEPPVRATLV 1958
Query: 2755 RTGASRYHLIYTNHHILMDGWSGSQLFGEVLQHYAGEPLRAPIGR--------------- 2799
R + L HHI+ D WS LF + + Y P
Sbjct: 1959 RMADDCHVLHLVLHHIVSDDWSLGLLFADFSRLYRDYCAAGPAASVTSVASIADDERIAA 2018
Query: 2800 -----YRDYI----AWLQAQDKSVSEAFWKAQLLNLQE-PTRLARGLQAAQSEALAVNG- 2848
YR+ I A L + + A+W+A L N E P LA +S + G
Sbjct: 2019 TSAAAYRELISARAARLTPERELQQLAWWRAALTNDDESPATLALPYDRTRSGSRCAPGA 2078
Query: 2849 EHRLNLDASQTAQLKAFAQRHKVTLNTLVQSAWLLLLQHHTGQATVAFGATVAGRPAQLR 2908
HR+ + A L+A A + TL + +A LL ++GQ+ + G +AGR L
Sbjct: 2079 RHRVRVPAGTAHALRALASARRATLFMTLLAAVDALLYRYSGQSDIRLGVPLAGR--DLP 2136
Query: 2909 GIEQQVGLFINTLPVVATPDAQMTVSQWLQQIQAQNVRLREQEHTPLFEI----QRWAGL 2964
G G F+NT+ + TP + +Q + ++ + + + P + Q L
Sbjct: 2137 GAADVAGFFVNTVVIRTTPRGETRAAQLIDDVRERLLGAYANQDVPFASVVKAVQPERDL 2196
Query: 2965 GGEALFDSILVFENYPVSEALEQGAPSGLTFGAVHSLE-QTHYPLTVLLGIGDTLGMEFN 3023
LF +LV + A G +T V + E Q L + + + F
Sbjct: 2197 AQTPLFQ-VLVNQQQRHDLAASFGEGLRVTVQEVDNGEAQFDLMLNIAEAADGAIDLAFT 2255
Query: 3024 YDRHAFSAAHIEQLAEHFQQLLQALAVDGAQRLAT--LPSLASTERETVLHAWNATAADY 3081
Y F A+ IE+LA +F LL + R+A+ LP L + +T A
Sbjct: 2256 YATDVFDASTIERLARNFTGLLDQWSAAPDARIASFELPELGDQPSPRL----PSTFAYE 2311
Query: 3082 PLHLAVHQLIEAQVVRTPDAPALVFAGQVLSYAALNRRANRLAHRLIAAGVGPDVLVGLA 3141
P V I AQ P+A ALV + ++YA L+ + +AH L G + VG+A
Sbjct: 2312 P----VTTRIAAQARARPEAVALVDGDEHVTYAQLDVWSRAIAHELRRLGATAETRVGVA 2367
Query: 3142 VERSIEMVVGLLAVLKAGGAYVPLDPEYPRDRLAYMLQDSDVKLLLTQAHLLEQLPIPTG 3201
++RS +V LL VL+AG AYVPLDP YP RL ++L DS ++L++T A L Q G
Sbjct: 2368 MQRSAALVASLLGVLRAGAAYVPLDPSYPVGRLTHILDDSQLRLIVTDASSLAQHASLFG 2427
Query: 3202 LHSLVLEQG-DEWLQAYAEQNPLVTVDGENLAYVIYTSGSTGQPKGAGNRHSALTNRLCW 3260
V + + A A + + LAYVIYTSGSTG PKG G H +
Sbjct: 2428 SRPTVDAVALRDAVPADATDDAGAYPHPQQLAYVIYTSGSTGVPKGVGVTHENVARLFDA 2487
Query: 3261 MQHAYGLEGSDTVLQKTPFSFDVSVWEFFWPLMTGARLVVAAPGDHRDPARLVSLINAEH 3320
Q + + D ++FD SVWE F L+ GARLV+ R+PA +L+ E
Sbjct: 2488 TQSRFAFDAQDVWTLFHSYAFDFSVWEMFGALVHGARLVIVPHWSAREPAAFHALLRKEQ 2547
Query: 3321 VTTLHFVPSMLQAFLQDAGVGACHSLQRIVCSGEALPVDAQQQVFAKLPHAG----LYNL 3376
VT L+ PS +Q SL+ ++ GE L + G L N+
Sbjct: 2548 VTVLNQTPSAFVQLIQTDDGNTLDSLRAVIFGGERLEPSLLARWAEGARRKGTLPALVNM 2607
Query: 3377 YGPTEAAIDVTHWT----CVDEGRDAVPIGRPIANLGCYVLDGNLEPAPVGVLGELYLGG 3432
YG TE + VTH T + +GR IG P+ +L +VLD +L P+G +GELY+GG
Sbjct: 2608 YGITETTVHVTHRTLDEAALRDGRSV--IGAPLDDLTLHVLDADLNRVPLGAVGELYVGG 2665
Query: 3433 VGLARGYHRRPALTAERFVTDPFGS-GSRLYRTGDLARYRDDGVIEYAGRIDHQVKLRGL 3491
GLARGY R AL+A+RFV DP+G+ G+RLYR+GDLAR DG +EY GR D QVK+RG
Sbjct: 2666 AGLARGYLGRAALSAQRFVPDPYGAPGARLYRSGDLARRLPDGDLEYLGRNDDQVKIRGF 2725
Query: 3492 RIELGEIEARLLEHACVREAAVLAV-----------DGTHLVGYLVLQ-APSEDWKAQVA 3539
RIELGEI+A L H VR+ AVLA D L+ Y+V + P+ +
Sbjct: 2726 RIELGEIQAALRAHPEVRDVAVLASGHGNGNGNNANDNRRLIAYVVPRGGPNAGDAGRWQ 2785
Query: 3540 MHLAAQLPDYMVPAQWVVLTQMPLSPNGKLDRKALPKPEAQGAGAYQ--APQSAIEQQVA 3597
LAA+LP +MVP+ +V L + PL+PNGKLDR+ALP PEA A A Q A + E +
Sbjct: 2786 TWLAARLPGHMVPSSYVELERFPLTPNGKLDRRALPAPEAV-ANAKQGVAASTPAEAALL 2844
Query: 3598 AIWRDVLGVERVGLNDNFFELGGHSLLVLMLKERIRKVSGVGLSVSQLML--NPTVR 3652
A+WR VL + +G+ DNFF +GG S+L L + + K GL V+ M+ PTV+
Sbjct: 2845 AVWRAVLRRDDIGVTDNFFVIGGDSILSLQI---VAKARDAGLHVTPRMVFEAPTVQ 2898
Score = 343 bits (879), Expect = 9e-97
Identities = 239/634 (37%), Positives = 330/634 (52%), Gaps = 71/634 (11%)
Query: 1572 VADRAGETPEAVAVKFGEQQLTYGELDRQANRLAHALIARGVGPEVRVAIAMPRSAEIMV 1631
VA A E P+AVA+ L + +L + + RLA AL+A GV P RV +A+PR +
Sbjct: 15 VARFAIERPDAVALVDSTGALVWRDLWQWSGRLAAALVAEGVRPGDRVVLALPRCTAFVA 74
Query: 1632 AFLAVMKAGGVYVPLDIEYPRDRLLYMMQDSRARLLLT---------------------H 1670
A LAV + YVPLD P RL + +D AR+++T H
Sbjct: 75 AILAVWRVRACYVPLDPALPEARLRWQAEDCGARVVMTGAALTSGALDAVVEGVAADAVH 134
Query: 1671 ST-------------------VQQRLPIPDGLEALAVDQTQAWSA-------NDDSAPEV 1704
+T Q +PD A A+D T A S+ + S+ +
Sbjct: 135 ATNAAMRTDGPRWLPEGVTTLDPQAFRVPDDAAAKALDTTNAASSEIFHHAMSGPSSDDS 194
Query: 1705 VLDGDNLAYVIYTSGSTGMPKGVAVSHGPLVAHIIATGERYETSPADCELHFMSFAFDGS 1764
VL AYVIYTSGSTG PKGV +SH L A++ ER A + + A D
Sbjct: 195 VLIWP--AYVIYTSGSTGRPKGVVLSHAALAAYLQGLSERLPEGIASA-AYLSTTAADLG 251
Query: 1765 HEGWMHPLINGASV-LIRDDSLWLPEYTYQQMHRHHVTMAVFPPVYLQQLAEHAERDGNP 1823
H L +G ++ LI D P+ MH H V + P +L L + +
Sbjct: 252 HTSLFGALWHGWTLHLIDADVAADPDAFAAYMHTHSVDLLKIVPSHLDALLQAQSAEWVL 311
Query: 1824 PKVRVYCFGGDAVAQASYDLAWRALKP-TYLFNGYGPTETVVTPLLWKARKGDPCGAVYA 1882
P+ + G A + + +A L+P L N YGPTET V L R G A
Sbjct: 312 PRRCLVLGGEPAPTRLAARIA--TLRPECQLINHYGPTETAVGVL---TRAGAQTSAGTL 366
Query: 1883 PIGTLLGNRSGYVLDAQLNLQPIGVAGELYLGGEGVARGYLERPALTAERFVPDPFGKPG 1942
P+G L + ++DA N P G AGEL +GG VA GYL RP+LTAERFVPDP G G
Sbjct: 367 PLGKPLAHVKARIVDADGNAVPKGAAGELCIGGASVAHGYLNRPSLTAERFVPDPDGN-G 425
Query: 1943 SRVYRSGDLTRGRPDGGVDYLGRVDHQVKIRGFRIELGEIEARLREQDSVGETVVVAQEG 2002
+R+YR+GD +R PDG +LGR+D Q+KIRGFR+E E+ ARLR + V + VV+A
Sbjct: 426 ARLYRTGDRSRRLPDGEYAFLGRLDDQLKIRGFRVEPEEVAARLRNEHGVRDAVVIAYAD 485
Query: 2003 PSG--KQLVAYVVPLDPLLIDDAVAQSTCREALRRALKARLPDYMVPTHLMFLERMPLTP 2060
G +LVAY+ + A+S EA+R L A LPDYMVP+ L L +PLTP
Sbjct: 486 SDGAAPRLVAYL----------SAAESLDVEAIRSRLAAELPDYMVPSSLQVLAALPLTP 535
Query: 2061 NGKLDRKGLPRP-DVSQMQQVYVAPQSELEQKIAAIWSDVLRLPRVGLHDNFFELGGDSI 2119
NGK+DR LP P + V P+++ E+ + IW VL+ +G+ DN+FE+GGDSI
Sbjct: 536 NGKIDRAALPAPLQENTAGAARVEPRNDAERTLIGIWKLVLKRDDIGVTDNYFEIGGDSI 595
Query: 2120 ISIQVVSRARQAGVRFTPKDLFQHQTVQSLAAVA 2153
+S+Q++++AR AG++ TPK +F H T+++ A VA
Sbjct: 596 LSLQIIAKARGAGLKLTPKQMFDHPTIEAAARVA 629
Score = 289 bits (739), Expect = 2e-80
Identities = 212/609 (34%), Positives = 298/609 (48%), Gaps = 59/609 (9%)
Query: 3096 VRTPDAPALVFAGQVLSYAALNRRANRLAHRLIAAGVGPDVLVGLAVERSIEMVVGLLAV 3155
+ PDA ALV + L + L + + RLA L+A GV P V LA+ R V +LAV
Sbjct: 20 IERPDAVALVDSTGALVWRDLWQWSGRLAAALVAEGVRPGDRVVLALPRCTAFVAAILAV 79
Query: 3156 LKAGGAYVPLDPEYPRDRLAYMLQDSDVKLLLTQAHLLEQL--PIPTGL--------HSL 3205
+ YVPLDP P RL + +D ++++T A L + G+ ++
Sbjct: 80 WRVRACYVPLDPALPEARLRWQAEDCGARVVMTGAALTSGALDAVVEGVAADAVHATNAA 139
Query: 3206 VLEQGDEWL---------QAY-----AEQNPLVTVDGENL-------------------- 3231
+ G WL QA+ A L T + +
Sbjct: 140 MRTDGPRWLPEGVTTLDPQAFRVPDDAAAKALDTTNAASSEIFHHAMSGPSSDDSVLIWP 199
Query: 3232 AYVIYTSGSTGQPKGAGNRHSALTNRLCWMQHAYGLEGSDTVLQKTPFSFDVSVWEFFWP 3291
AYVIYTSGSTG+PKG H+AL L + EG + + + D+ F
Sbjct: 200 AYVIYTSGSTGRPKGVVLSHAALAAYLQGLSERLP-EGIASAAYLSTTAADLGHTSLFGA 258
Query: 3292 LMTGARLVVAAPGDHRDPARLVSLINAEHVTTLHFVPSMLQAFLQDAGVGACHSLQRIVC 3351
L G L + DP + ++ V L VPS L A LQ + +V
Sbjct: 259 LWHGWTLHLIDADVAADPDAFAAYMHTHSVDLLKIVPSHLDALLQAQSAEWVLPRRCLVL 318
Query: 3352 SGEALPVDAQQQVFAKLPHAGLYNLYGPTEAAIDVTHWTCVDEGRDAVPIGRPIANLGCY 3411
GE P ++ P L N YGPTE A+ V +P+G+P+A++
Sbjct: 319 GGEPAPTRLAARIATLRPECQLINHYGPTETAVGVLTRAGAQTSAGTLPLGKPLAHVKAR 378
Query: 3412 VLDGNLEPAPVGVLGELYLGGVGLARGYHRRPALTAERFVTDPFGSGSRLYRTGDLARYR 3471
++D + P G GEL +GG +A GY RP+LTAERFV DP G+G+RLYRTGD +R
Sbjct: 379 IVDADGNAVPKGAAGELCIGGASVAHGYLNRPSLTAERFVPDPDGNGARLYRTGDRSRRL 438
Query: 3472 DDGVIEYAGRIDHQVKLRGLRIELGEIEARLLEHACVREAAVLAV---DGT--HLVGYLV 3526
DG + GR+D Q+K+RG R+E E+ ARL VR+A V+A DG LV YL
Sbjct: 439 PDGEYAFLGRLDDQLKIRGFRVEPEEVAARLRNEHGVRDAVVIAYADSDGAAPRLVAYL- 497
Query: 3527 LQAPSEDWKAQVAMHLAAQLPDYMVPAQWVVLTQMPLSPNGKLDRKALPKP--EAQGAGA 3584
A S D +A + LAA+LPDYMVP+ VL +PL+PNGK+DR ALP P E A
Sbjct: 498 SAAESLDVEA-IRSRLAAELPDYMVPSSLQVLAALPLTPNGKIDRAALPAPLQENTAGAA 556
Query: 3585 YQAPQSAIEQQVAAIWRDVLGVERVGLNDNFFELGGHSLLVLMLKERIRKVSGVGLSVS- 3643
P++ E+ + IW+ VL + +G+ DN+FE+GG S+L L + I K G GL ++
Sbjct: 557 RVEPRNDAERTLIGIWKLVLKRDDIGVTDNYFEIGGDSILSLQI---IAKARGAGLKLTP 613
Query: 3644 -QLMLNPTV 3651
Q+ +PT+
Sbjct: 614 KQMFDHPTI 622
Score = 70.9 bits (172), Expect = 9e-15
Identities = 42/117 (35%), Positives = 60/117 (51%)
Query: 3662 ARSSLIVKLNSQTEGTPLFMFHPSFGSVHCYTAIALALREQRPVFGVICRALAEAGAEVP 3721
A SS V LN+ LF HP +G V Y +A AL + + + AL E
Sbjct: 4532 AVSSPAVPLNALGSPATLFCLHPGYGMVGEYRTLAQALNGRVTLIAMQAPALRGEPWEGD 4591
Query: 3722 EWQAMVEDYAEQLLLAQPQGAFRLAGWSLGGNLAMEVAYVLEQAGRDVEFVGWIDSA 3778
++A+ YA+++ QP G + L GWS GG LA+ +A E+ G V FVG +D+A
Sbjct: 4592 SFEALAAHYAQRIETLQPHGDYALLGWSFGGRLAIAIADHFERRGARVSFVGIVDTA 4648