Pairwise Alignments

Query, 649 a.a., DNA topoisomerase III from Pseudomonas simiae WCS417

Subject, 670 a.a., DNA topoisomerase III (RefSeq) from Shewanella loihica PV-4

 Score =  435 bits (1118), Expect = e-126
 Identities = 260/660 (39%), Positives = 377/660 (57%), Gaps = 28/660 (4%)

Query: 1   MRLYLCEKPSQAKDIAAVLGAS-RRGDG-CWLGNGVTVTWCIGHLLETAPPDAYDEKYKR 58
           M LY+ EKPS  + IA VL    ++G+G     NG TV+WCIGHLLE A PD+YD  +K 
Sbjct: 1   MILYIAEKPSLGRAIADVLPKPHKKGEGYITAANGDTVSWCIGHLLEQAEPDSYDPAFKS 60

Query: 59  WVLADLPIVPEKWKMRVKPKTASQFKAVKRLLGEAQELVIATDADREGEMIARELVEHCR 118
           W    LPIVP++WKM  K KT  Q   +++L+ +A +LV A D DREG+++  E++ +  
Sbjct: 61  WSFDHLPIVPQQWKMTPKSKTRGQLSVLRKLVKQASQLVNAGDPDREGQLLVDEVIAYLG 120

Query: 119 YRGP----IQRLWLSALDDASIRKALAALKPGAETFSLYHSALGRSRADWLIGMNMSRLF 174
            +G      QRL +S L+  ++++AL  L+   E   L  SAL RSRADWL GMNM+R +
Sbjct: 121 VKGDKLEQTQRLLVSDLNPQAVKRALGQLRSNREFIPLSTSALARSRADWLYGMNMTRAY 180

Query: 175 TLLGRQSGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVAYWAIDVDLQ-HERITFTAQW 233
           TL GR+ GYQGVL VGRVQTP L LVV RD +I  FV   ++ +  +L   E+  F A+W
Sbjct: 181 TLQGRKVGYQGVLSVGRVQTPLLGLVVRRDEAIEHFVSKPFYEVLANLYTQEQAHFKAKW 240

Query: 234 RAAEDAC----DDQGRCLDPQLARDAADAMRNAATARLVKLRTERMREVAPLPFDLGTLQ 289
           + +E AC    D++GR L  +LA +    +     A++  L+ +  ++  PLP++L +LQ
Sbjct: 241 QPSE-ACQPYMDEEGRVLSRRLAENVVGRITEQP-AKVTDLQAKDKQQGQPLPYNLSSLQ 298

Query: 290 EICSKKLGLGAQETLDIAQSLYETHKVITYPRSDCGYLPLSQHSEAPKILAALARADAAV 349
              +K+ G+ A+  LD  QSLYE HK+ITYPRSD  YLP  Q + AP ++ A+ +    +
Sbjct: 299 IDAAKRFGMSAKTVLDTCQSLYEKHKLITYPRSDSRYLPKEQLALAPSVIGAVLKGAGEL 358

Query: 350 NELMPHIETQRRSRAWNDAKVSAHHGIIPTGAGKDVGQLTGKHRAVYTLIRARYLAQFLP 409
                  + +  S+AWNDAKV AHH I+PT    ++  LT   + +Y  +  +YLAQF P
Sbjct: 359 TAQCAAPDLKIVSKAWNDAKVDAHHAIVPTEKVANLSALTQAEKQIYLQLARQYLAQFYP 418

Query: 410 NHEYDRTQADFDCAGQALRAVGKVVIEPGWKRALPEAL---APAKGREAPAPQALPALVQ 466
            + Y  TQ + + AG       K  I  GWK+  P+        +G EA A   LP L +
Sbjct: 419 VYRYHETQVEVEIAGGHFHTKAKQEIALGWKQLFPKRSDDKTDGEGDEALAQ--LPPLHK 476

Query: 467 GQDYAVAKVNLKDLWTQPPKPFTEGDLIKAMKNVAKLVEDPLLKQKLKDTTGIGTEATRA 526
           GQ     +  L +  TQPPK FT+  L+ AM  +++ V +P +++ LK+T G+GTEATRA
Sbjct: 477 GQMLHSGQGELIEKQTQPPKAFTDATLLSAMTGISRYVTNPEIRKILKETDGLGTEATRA 536

Query: 527 GIIQGLLDRGYLVKNGKALSATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMSLE 586
           GII+ L  RG+L + GK++ +TP    LI+++P +   P  TA+WE  LD +   E    
Sbjct: 537 GIIELLFKRGFLARQGKSIVSTPVGRGLINSLPESATTPDMTALWESHLDAISRKE---- 592

Query: 587 EFVAKQAAWMSKQVARCNGMRMTITGPASPAGRGATPWK---KKRKSAPRKTAASPKRAK 643
              AK  ++M+  V   NG+ M        A +G    K   KKR    R+  A+  + K
Sbjct: 593 ---AKYLSFMAPLVESLNGLIMQAGAQLPKALQGVEAPKRSFKKRGYGNRRGTATGAKGK 649