Pairwise Alignments

Query, 360 a.a., D-malate dehydrogenase [decarboxylating] (EC 1.1.1.83) from Variovorax sp. SCN45

Subject, 363 a.a., 3-isopropylmalate dehydrogenase from Vibrio cholerae E7946 ATCC 55056

 Score =  201 bits (511), Expect = 3e-56
 Identities = 143/367 (38%), Positives = 204/367 (55%), Gaps = 21/367 (5%)

Query: 3   KKHRIAVIPGDGIGVEVMPEGLRVLDAVGRRFGIDFSYDHFDWGSDHYVRTGLMMPADWA 62
           + ++IAV+PGDGIG EVM +  +VLDA+ ++ GI FS +  D G       G  +P    
Sbjct: 4   RDYKIAVLPGDGIGPEVMAQAHKVLDAIEQKHGIRFSREEHDVGGIAIDNHGCPLPESTL 63

Query: 63  DKIQGHDAIYFGAVGAPD---KVPDHIAVWGLLIKIRRDFDQYVNLRPVRLMPGVPG--P 117
              +  DA+ FG+VG P      P+     G L+ +R+ F  + NLRP ++  G+    P
Sbjct: 64  RACEEADAVLFGSVGGPKWEHLPPNEQPERGALLPLRKHFQLFCNLRPAQIHQGLEAFSP 123

Query: 118 L-AHRKPGDIDFLVVRENTEGEYTSVG-GRLFEGTPREMAIQEAVFTRTGVDRIIDYAFT 175
           L A       D +VVRE T G Y     GR  EG   E A    V+ R  ++RI   AF 
Sbjct: 124 LRADISARGFDIVVVRELTGGIYFGQPKGREGEGA-HEKAFDTEVYHRFEIERIARIAFE 182

Query: 176 LANRRKRKSLTAATKSNGISITMPYWDERLAEIAKRYPDVATNKFHIDILCAHFVQHPDW 235
            A R +RK + +  K+N +  ++  W E ++EIAK YPDV+ +  +ID      ++ P  
Sbjct: 183 SA-RLRRKKVCSIDKANVLQSSI-LWREVVSEIAKEYPDVSLSHMYIDNATMQLIKDPAQ 240

Query: 236 FDVVVASNLFGDILSDLGPACTGTIGIAPSANLNPERKFPSLFEPVHGSAPDIAGKGIAN 295
           FDV++ SN+FGDILSD     TG++G+ PSA++N E KF  L+EP  GSAPDIAGK IAN
Sbjct: 241 FDVMLCSNIFGDILSDECAMITGSMGMLPSASMN-ESKF-GLYEPAGGSAPDIAGKNIAN 298

Query: 296 PIGQIWSAALMLDH-LGNDDPVYAQASAAVVSAIETVLSEGPRTRDMGGT---ANTVDVG 351
           P+ QI SAALML + LG +      A+  + +A+   L+ G  T D+ G+    +T  +G
Sbjct: 299 PVAQILSAALMLRYSLGEE-----AAARDIENAVSQALAAGELTADLAGSKPALSTSAMG 353

Query: 352 RAIADCI 358
             IA  I
Sbjct: 354 DKIASYI 360