Pairwise Alignments

Query, 926 a.a., Isoleucyl-tRNA synthetase (EC 6.1.1.5) from Variovorax sp. SCN45

Subject, 886 a.a., valine--tRNA ligase from Methanococcus maripaludis S2

 Score =  239 bits (609), Expect = 7e-67
 Identities = 191/768 (24%), Positives = 333/768 (43%), Gaps = 94/768 (12%)

Query: 25  EPELVKRWAEQRVYERMRAAAAGRPPFILHDGPPYANGDIHIGHAVNKVLKDMVFKSRFF 84
           E ++ ++W +++ ++ +      RPP+I+   PPY  G +H+GH +N    D++ + +  
Sbjct: 12  EKKVQEKWEDEKTFKFLDDEK--RPPYIIDTPPPYPTGRMHLGHGLNWTYMDIIARFKRM 69

Query: 85  DGFDSQWIPGWDCHGMPIEHRIEQTNG---RGLPTEQVQQLCRDYALQQTQSQKKDFLRL 141
           +G+D  +  GWDCHG+P E ++E+ N      +   + ++LC +   +  +  +     L
Sbjct: 70  NGYDVLFPQGWDCHGLPTEVKVEELNNITKSDIDRHEFRRLCVELTDENVEKMRGQVRSL 129

Query: 142 GLLGDWDRAFRTMDFE-TEANEIRFLDRIRQRGLLFRGQKPVNWCVDCQSALAEAELEYA 200
           G+  DWDR + TM+ +    ++  FL ++ ++GL++RG+ PVNWC  C++A+A AE+EY 
Sbjct: 130 GISIDWDREYITMNPDYVRKSQTAFL-KMYEKGLIYRGKHPVNWCPRCETAIAFAEVEYQ 188

Query: 201 PKRSTTAYVGLLALDAVDFASRFKCQPMPGKQARLTIWTTTPWTLPGNVAVGLDPRASYG 260
            + S   Y+            +F      GK   L I T+ P  +   V + + P     
Sbjct: 189 GRTSKLNYI------------KFPYAENSGKY--LEIATSRPELMAACVGIVVHPE---- 230

Query: 261 LYDTPNGMLVMAAETGGKLLAGLGIDHELCAVAPGLDLVGLRLKHPLLDTEVPLVAADFV 320
                                    D          D+VG  +K PL D EV +     V
Sbjct: 231 -------------------------DERYS------DVVGKTVKVPLFDQEVNVYPDSDV 259

Query: 321 SLDTGTGLVHLAPAHGAEDFELCRSLGIGGENVIDGAGRFVAGLPMVGGMGLEEGSKLIL 380
             + GTG+V +       D        +  +  I+  G+         G   ++  K I+
Sbjct: 260 EKEFGTGVVMVCTFGDKTDVTWVNRHKLEVKKAINEKGQLTEICGKYAGKKSDDARKEII 319

Query: 381 DMLQADGSLLKQERIEHSYPHCWRHKTPILFRSTTQWFIGMDRRATGDTRTLRETAREAI 440
             L ++  ++KQE +E +   CWR KTPI      QWF+ +       T+ L E    A 
Sbjct: 320 SDLISENYMIKQEPLEQNVGSCWRCKTPIEIIVGDQWFVNV-------TKLLTE-VENAA 371

Query: 441 RDVPFYPASGRSRMEAMIDGRP-DWCVSRQRTWGVPLPFFVRRSDKSLHPQTARLVEEVA 499
            ++ + P   ++R+   I+    DWC+SRQR +  P+P +  +             E + 
Sbjct: 372 NEISWVPEHMKARLMKWIEDMGWDWCISRQRLFATPIPVWYCKD----------CGEIIV 421

Query: 500 LRIEREGISAWTRLKPADLGVDEAEYEKLSDTLDVWFDSG---SIHATVYRDARRPDAHG 556
            + E   I   T+  P       +     +D LD W DS     + A    D      H 
Sbjct: 422 AKPEDLPIDP-TKESPYTCKCGNSNLVAETDVLDTWMDSSITPLVIAGWLEDEEFFKKH- 479

Query: 557 YPADLYLEGSDQHRGWFGSSLMTGCAADARAPFKAVLTHGFAVDGDGKKMSKSLGNTVSP 616
           YP  L  +G D  R W   +++   A     P+  ++ +G     DG KMSKS GN V P
Sbjct: 480 YPVQLRPQGHDIIRTWAFYTMVRSLAITGEKPWDEIVINGMVFGEDGFKMSKSRGNVVEP 539

Query: 617 QQVASTRGADIIRLWIASTDYSTDISVSEEILDRVVEMYRRIRNTIRFLLLNVSDFD-AT 675
            ++  T GAD +RLW +++    D+  + + ++      R+I N  +F  +N+SD   + 
Sbjct: 540 GEITKTYGADALRLWASNSTIGKDVPFAWKEVEYGGRFLRKIWNACKFAKMNISDETISE 599

Query: 676 ADCMRAQDLES-VDQYAMLRCRELAEQCRKSYREYDFVAVTR----LLHGYCADELGGFY 730
              + +  +E+ VD + + +   L  +       Y    V      L H +C +     Y
Sbjct: 600 LKSLNSISIENPVDLWILSKLNNLISKVSDDLGNYKINTVVEIQKFLWHEFCDN-----Y 654

Query: 731 LDVLKDRLY---ASARDSRERRSAQTALHAILKNLLLLTAPILSFTAE 775
           ++++K RLY    S    +E+  AQ  L+ ++   + L  P     AE
Sbjct: 655 IEMVKHRLYNKEESESAQQEKLMAQYTLYKVITESVKLLTPFTPHFAE 702