Pairwise Alignments

Query, 987 a.a., DNA topoisomerase III, Burkholderia type (EC 5.99.1.2) from Variovorax sp. SCN45

Subject, 647 a.a., DNA topoisomerase III from Vibrio cholerae E7946 ATCC 55056

 Score =  303 bits (777), Expect = 2e-86
 Identities = 206/639 (32%), Positives = 335/639 (52%), Gaps = 35/639 (5%)

Query: 5   LVIAEKPSVAQDIVRALTPVAGKFDKHDEHFENDSYVVTSAVGHLVEIQAPEEFDVKRGK 64
           L IAEKPS+A+ I  AL P   K ++      N   +VT  +GHL+E   P+ +D +  K
Sbjct: 4   LFIAEKPSLARAIADAL-PKPHKKEQGCIRCANGD-IVTWCIGHLLEQVEPDAYDERYKK 61

Query: 65  WSFANLPVIPPHFDLKPVDKTKTRLNAVVKQAKRKDVTQLINACDAGREGELIFRLIEQY 124
           W+ A+LP+IP  + L+P   +  +L  V K  K  + TQ+I+A D  REG+L+   +  Y
Sbjct: 62  WNMADLPIIPEQWQLRPRKSSSQQLTVVRKLLK--EATQIIHAGDPDREGQLLVDEVIDY 119

Query: 125 AGGKSGLNKPVKRLWLQSMTPQAIRDGFDALRTEKQMQGLADAARSRSEADWLVGINGTR 184
                   + V+RL +  +   A++     LR+ ++   L+ +A +RS ADWL G+N +R
Sbjct: 120 CKVPKSKKETVQRLLISDLNLSAVKRALQGLRSNREFIPLSVSALARSRADWLYGMNMSR 179

Query: 185 AMTAFNSRDGGFFLTTVGRVQTPTLSVVVEREEQIRKFVSRDYWEIHGTFAAEAG-EYPG 243
           A T    + G   + +VGRVQTP L +VV R+E+I  F+  DY+ +      + G EY  
Sbjct: 180 AYTLLGKKAGYQGVLSVGRVQTPVLGLVVRRDEEIEHFIPHDYFTLDALIPYQNGTEYFD 239

Query: 244 KWFNPDWKKANAPLLANGEPDPEQRADRVWNEQEARAIADAARGKPATVTE-ESKPTTQA 302
                 WK + A L    E        RV N +    +A     +PATVTE E   T QA
Sbjct: 240 --IRARWKPSEACLPWQDE------EGRVTNRKLVDNVASRIANQPATVTESEQDQTKQA 291

Query: 303 SPMLFDLTSLQREANGRFGFSAKTTLALAQSLYERHKALTYPRTDSRALPEDYLPVVKDT 362
           +P+ + L++LQ +A  R+ FSA+  L L QSLYE+HK +TYPR+D R LP+++L    D 
Sbjct: 292 APLPYSLSALQIDAAKRYNFSAQQVLDLCQSLYEKHKLITYPRSDCRYLPKEHLAQAPDV 351

Query: 363 MGMLANSGMKHLAPFAKQAVDGNYVRPNKRIFDNAKVSDHFAIIPTLQAPS--GLSEAEQ 420
           +  +AN+  + +      AV+   +    + ++++KV  H AIIPT +  S   LS  E 
Sbjct: 352 VAAIANNAQEMVT-----AVNDADLSLRSKAWNDSKVDAHHAIIPTPKKASVNALSGHEM 406

Query: 421 KLYDFVVRRFLSVFFPSAEYQVTTRISTVEQGGKKYPFRTDGKVLVKPGWLAIYGKEAQD 480
           K+Y  + R++L  F+P+A Y     +  +  G     F   G+ L+  GW  + G   Q 
Sbjct: 407 KVYQLIARQYLMQFYPAAIYAEAKLVFNIAGG----IFIAKGRQLLSAGWKVLTG---QQ 459

Query: 481 DEKEDDKDGKRLVPVKPGEIVKTESADTKGLKTRPPARYSEATLLGAMEGAGKTIDDDEL 540
           DE+E+  D  ++ P+  G +++    + K  +T PP  ++EATLL AM G  + + D EL
Sbjct: 460 DEQEECVD--KVPPLPVGIVLQCREGEIKQRQTEPPRHFTEATLLQAMTGIARFVADKEL 517

Query: 541 REAMQE-KGLGTPATRAATIEGLITEKYMLREGRELIPTAKAFQLMTLLRGLGVEELSKA 599
           ++ ++E  GLGT ATRA  ++ L     + R+ + +  T     L+  L      E +  
Sbjct: 518 KKILRETDGLGTEATRAGILDTLFKRGLLQRDNKLIKSTPAGRGLIHAL----PSEATYP 573

Query: 600 ELTGEWEYKLAQMEKGALSRDAFMREIAQMTEHIVKKAK 638
           ++T  WE++L  + +   +   FM+ +    E ++++ +
Sbjct: 574 DMTAHWEHQLQAIAEKGQAYQPFMQTLQGRLEQLIEQVQ 612