Pairwise Alignments

Query, 473 a.a., 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) from Variovorax sp. SCN45

Subject, 424 a.a., 3-isopropylmalate dehydratase large subunit from Methanococcus maripaludis S2

 Score =  218 bits (556), Expect = 2e-61
 Identities = 154/475 (32%), Positives = 235/475 (49%), Gaps = 58/475 (12%)

Query: 1   MARTLYDKIWDEHVVHTEEDGTAILY--IDRHLVHEVTSPQAFEGLREAG-RKLWRISSV 57
           MA TL +KI  +   ++E     I+   ++  +VH++T P +   L++ G  K+W    +
Sbjct: 1   MAMTLAEKILAKASGNSEVSPGDIVMAKVETAMVHDITGPLSVNTLKKEGISKVWDNEKI 60

Query: 58  VATADHNTPTTGWERGYEGIADPTSKEQVTTLDHN-IAEFGAAAFFPFLSKRQGIVHVIG 116
           V   DH  P           AD  +  +   L  N + E     F+     R+G+ H + 
Sbjct: 61  VIPFDHQIP-----------ADSINAAENHILMRNFVKEQNIKHFYDI---REGVCHQVL 106

Query: 117 PESGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVMATQTLLGKKAKNMLVKVDG 176
           PE G  +PG  VV  DSHT T+GAFGA A GIG++++    AT  L  K  + +   + G
Sbjct: 107 PEKGHIVPGTVVVGADSHTCTYGAFGAFATGIGSTDMAAAFATGELWFKVPETLYFNITG 166

Query: 177 KLPLGCTAKDIVLAIIGKIGTAGGTGYTIEFAGSAIRDLSMEGRMTVCNMAIEAGARAGL 236
           +L     +KD++L+IIG +G  G T    +FAG+ + ++++  RMT+ NMAIE G +AGL
Sbjct: 167 ELKPEVMSKDVILSIIGMVGADGATYKAAQFAGNTVDNMTIASRMTMSNMAIEMGGKAGL 226

Query: 237 VAVDEKTISYVKGRPLAPTGVEWDQAVSYWRTLQSDPGAKFDAVVELDAATIPPQVTWGT 296
           +A D+KTI+YVK        +E +     +  +  D  A+F+   E+D + + P +    
Sbjct: 227 IAPDDKTINYVK------NAMEANNTAKPFELVLGDKNAEFEEKFEIDVSNLEPVMACPH 280

Query: 297 SPEMVVEINGRVPDPDKEKDANKRGAIERALVYMGLEPNKAMNDIFIDKVFIGSCTNSRI 356
           + + V  +      P                               ID+VFIGSCTN R+
Sbjct: 281 NVDNVKAVREVAGTP-------------------------------IDQVFIGSCTNGRL 309

Query: 357 EDMREAAAVVKKLGQKVAKNVKLAMVVPGSGVVKEQAEREGLDVIFKAAGFEWREPGCSM 416
           ED+R A  V++K G  ++K++++ +V P S  +  +A  EGL   F   G     P CS 
Sbjct: 310 EDLRAALNVIEKHG-GISKDIRV-VVTPASRSIMLEAIDEGLIKKFYQYGCVVTNPSCSA 367

Query: 417 CLAMNADRLEPGERCASTSNRNFEGRQGA-GGRTHLVSPAMAAAAAVHGHFVDVR 470
           C+      L PGE   +TSNRNF GR+G+     +L SP  AAA AV G  VD R
Sbjct: 368 CMGALYGLLGPGEVGIATSNRNFRGREGSLESDVYLASPITAAACAVKGEIVDPR 422