Pairwise Alignments

Query, 297 a.a., Porphobilinogen deaminase (EC 2.5.1.61) from Variovorax sp. SCN45

Subject, 304 a.a., hydroxymethylbilane synthase from Methanococcus maripaludis S2

 Score =  144 bits (362), Expect = 3e-39
 Identities = 98/296 (33%), Positives = 147/296 (49%), Gaps = 6/296 (2%)

Query: 2   IATRESRLALWQAEHVQALLQERGHTVSLLGITTTGDQILDRTLSKVGGKGLFVKELELA 61
           I TR S LA+ Q E++  LL +      ++ + TTGD+  ++ L+ +G  G+F KEL+  
Sbjct: 5   IGTRGSTLAMVQTEYIAGLLNDLDIETEIIIVKTTGDKDQNKKLADLG-IGVFTKELDNK 63

Query: 62  LEEGRADIAVHSLKDVPMDLPQGFALPCVLEREDPRDALVSPRFASLDQLPRGAVVGTSS 121
           + E   DIAVHSLKDVP        +    +RE P D ++  +    D       VGTSS
Sbjct: 64  MLENEIDIAVHSLKDVPTLWSDELQITATPKRESPDDIIIWRKDCDFDIEHDELNVGTSS 123

Query: 122 LRRVALLRALRPDLRIEPLRGNLDTRLRKLDEGQYDAIVLAAAGLKRLGLESRIRVAFDP 181
           +RR + L+   P+L  + LRGN+ TR+ KL  G+YD IV+A AGL R G++      +  
Sbjct: 124 IRRTSFLQFTNPNLTPKLLRGNVATRINKLRNGEYDTIVMAKAGLIRQGIDLS-EFNYKK 182

Query: 182 DTMLPAAGQGALGVEVRADRADLIELLASITHRGDWLSTAAERAVSRAMGGSCSMPLAAH 241
             +LPA  QG +GV  R   A + ++L  I  +  ++   AER   +  GG C  P  A 
Sbjct: 183 LDILPAPAQGVIGVASRKADAKINQILEKICDKKTYIEATAERWALKEYGGGCQAPFGAF 242

Query: 242 ARWQA-DGALRIDAAWGDPEGKAPLVKVH---ALAQAGDFTQADALGQHAAALLRE 293
           A +   +G L +     D +G    VK +    +    D   +  LG    A  +E
Sbjct: 243 AIYDTEEGILNLRCELVDEQGTIKRVKSNEGFVICTTDDVELSKELGARVGASFKE 298